DK0928787T3 - Fremgangsmåde til fremstillingen af 3-amino-pyrrolidinderivater - Google Patents

Fremgangsmåde til fremstillingen af 3-amino-pyrrolidinderivater

Info

Publication number
DK0928787T3
DK0928787T3 DK99100213T DK99100213T DK0928787T3 DK 0928787 T3 DK0928787 T3 DK 0928787T3 DK 99100213 T DK99100213 T DK 99100213T DK 99100213 T DK99100213 T DK 99100213T DK 0928787 T3 DK0928787 T3 DK 0928787T3
Authority
DK
Denmark
Prior art keywords
alkyl
formula
amino
chem
preparation
Prior art date
Application number
DK99100213T
Other languages
Danish (da)
English (en)
Inventor
Uwe Klinkhammer
Paul Spurr
Shaoning Wang
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Application granted granted Critical
Publication of DK0928787T3 publication Critical patent/DK0928787T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14Nitrogen atoms not forming part of a nitro radical
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99100213T 1998-01-12 1999-01-08 Fremgangsmåde til fremstillingen af 3-amino-pyrrolidinderivater DK0928787T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98100381 1998-01-12

Publications (1)

Publication Number Publication Date
DK0928787T3 true DK0928787T3 (da) 2002-09-23

Family

ID=8231254

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99100213T DK0928787T3 (da) 1998-01-12 1999-01-08 Fremgangsmåde til fremstillingen af 3-amino-pyrrolidinderivater

Country Status (10)

Country Link
US (1) US5977381A (fr)
EP (1) EP0928787B1 (fr)
JP (1) JP3639449B2 (fr)
KR (1) KR19990067824A (fr)
CN (1) CN1229077A (fr)
AT (1) ATE218546T1 (fr)
CA (1) CA2258166A1 (fr)
DE (1) DE69901627T2 (fr)
DK (1) DK0928787T3 (fr)
ES (1) ES2177139T3 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100295740B1 (ko) * 1998-09-17 2001-11-05 박영구 N-치환된-하이드록시고리화알킬아민유도체의제조방법
DK1148140T3 (da) * 2000-04-19 2007-01-08 Basilea Pharmaceutica Ag Fremgangsmåde til fremstilling af D-asparaginderivater
FR2817550B1 (fr) * 2000-12-01 2005-04-29 Ppg Sipsy Procede de preparation de derives de pyrrolidine substituee
US6348600B1 (en) * 2001-02-20 2002-02-19 Toray Industries, Inc. Methods for making optically active 3-aminopyrrolidine-2,5-dione derivative and optically active 3-aminopyrrolidine derivative
EP1491530B1 (fr) * 2002-03-29 2010-08-11 Kaneka Corporation Procede d'amelioration de la purete optique de 1-benzyl-3-aminopyrrolidine et sel utilise dans ce procede
CN1331852C (zh) * 2005-08-25 2007-08-15 浙江大学 N-取代基-3-氨基吡咯烷及其二盐酸盐的合成方法
CN101253143A (zh) * 2005-08-31 2008-08-27 辉瑞产品公司 直接氨基分解
WO2008013130A1 (fr) * 2006-07-28 2008-01-31 Kaneka Corporation Méthode de production d'un composé 3-amino-azoté optiquement actif
CN101759620B (zh) * 2010-01-19 2013-08-28 苏州天马精细化学品股份有限公司 3-氨基吡咯烷盐酸盐的合成方法
CN101955457A (zh) * 2010-09-21 2011-01-26 海门慧聚药业有限公司 光学活性3-氨基吡咯烷、3-氨基哌啶烷及其衍生物的一种通用制备方法
CN103570601B (zh) * 2012-07-20 2016-03-30 重庆博腾制药科技股份有限公司 一种光学活性药物中间体的制备方法
CN111592480B (zh) * 2020-06-18 2023-06-23 山西千岫制药有限公司 一种头孢吡普酯中间体(r)-1-叔丁氧基羰基-3-氨基吡咯烷的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1392194A (en) * 1971-09-23 1975-04-30 Wyeth John & Brother Ltd Pyrrolidine derivatives
US4785119A (en) * 1985-10-11 1988-11-15 Tokyo Kasei Kogyo Co., Ltd. 3-aminopyrrolidine compound and process for preparation thereof
US4916141A (en) * 1989-03-28 1990-04-10 Warner-Lambert Company (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
DE3910920A1 (de) * 1989-04-05 1990-10-11 Bayer Ag Enantiomerenreine 7-(3-amino-1-pyrrolidinyl)-chinolon- und -naphthyridoncarbonsaeuren
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines
JPH07233146A (ja) * 1994-02-23 1995-09-05 Dai Ichi Seiyaku Co Ltd ラセミ化法
JPH0853412A (ja) * 1994-08-11 1996-02-27 Sankyo Co Ltd 光学活性な3−アミノピロリジン誘導体
JP3716376B2 (ja) * 1995-10-26 2005-11-16 東レ・ファインケミカル株式会社 光学分割剤およびそれを用いた光学活性3−アミノピロリジン誘導体の製造法
US5703244A (en) * 1996-11-21 1997-12-30 Abbott Laboratories Process for preparation of chiral 3-amino-pyrrolidine and analogous bicyclic compounds
TW415949B (en) * 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents

Also Published As

Publication number Publication date
DE69901627D1 (de) 2002-07-11
DE69901627T2 (de) 2003-02-20
JP2000053642A (ja) 2000-02-22
US5977381A (en) 1999-11-02
CA2258166A1 (fr) 1999-07-12
ES2177139T3 (es) 2002-12-01
CN1229077A (zh) 1999-09-22
JP3639449B2 (ja) 2005-04-20
ATE218546T1 (de) 2002-06-15
EP0928787B1 (fr) 2002-06-05
EP0928787A1 (fr) 1999-07-14
KR19990067824A (ko) 1999-08-25

Similar Documents

Publication Publication Date Title
MY141255A (en) Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
DE69840296D1 (de) Phenylethylenamin-derivate
YU57603A (sh) Inhibitori fosfodiesteraze 4
ATE244227T1 (de) 4,4'-diaminostilben-2,2'-disulfonsäurederivate
DK0928787T3 (da) Fremgangsmåde til fremstillingen af 3-amino-pyrrolidinderivater
DE60135862D1 (de) Aliphatische stickstoffhaltige fünfgliedrige ringverbindungen
CY1106237T1 (el) Ετepοκυκλικα παραγωγα με 5 μελη στο δακτυλιο και εφαρμογη αυτων ως παρεμποδιστων της μονοαμινο οξυδασης
IS6257A (is) Frumuviðloðunartálmar
AU3599701A (en) Fluorescent probes for the quantitation of zinc
ES2182061T3 (es) 1 - (2 - desoxi - 2 - fluor-4- tio-beta-d arabinofuranosil)citosina.
HK1039316A1 (zh) 具有一氧化氮合成酶抑制作用的苯胺衍生物
ATE201195T1 (de) Tricyclische verbindungen
AU4491301A (en) Method of producing 6-substituted (s)-nicotine derivatives and intermediate compounds
HK1080472A1 (en) Process for the preparation of amino-pyrrolidine derivatives
ATE216415T1 (de) Pigmentszusammensetzungen
CA2221946A1 (fr) Procedes de preparation de composes cycliques
BRPI0415459A (pt) preparação de derivados de 3-azabiciclo[3.1.0]hexano
ATE222588T1 (de) Ein 1-methylcarbapenem-derivat
MXPA03012073A (es) Amidoderivados heterociclicos.
TW200719921A (en) Hair treating agent
ATE338057T1 (de) Peptidderivat, pharmazeutisch unbedenkliches salz davon, verfahren zu dessen herstellung und dessen verwendung
TW200510300A (en) Amino alcohol compounds
EP1340499A4 (fr) Nootropes
FR2794122B1 (fr) Nouveaux antioxydants, procedes de preparation et utilisations