DK0876393T3 - 21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold - Google Patents

21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold

Info

Publication number
DK0876393T3
DK0876393T3 DK96943204T DK96943204T DK0876393T3 DK 0876393 T3 DK0876393 T3 DK 0876393T3 DK 96943204 T DK96943204 T DK 96943204T DK 96943204 T DK96943204 T DK 96943204T DK 0876393 T3 DK0876393 T3 DK 0876393T3
Authority
DK
Denmark
Prior art keywords
pct
pregnant
thio
oxo
tetrahydrofuran
Prior art date
Application number
DK96943204T
Other languages
English (en)
Inventor
Keith Biggadike
Rosanne Mary Farrell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9526630.0A external-priority patent/GB9526630D0/en
Priority claimed from GBGB9613036.4A external-priority patent/GB9613036D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK0876393T3 publication Critical patent/DK0876393T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
DK96943204T 1995-12-29 1996-12-19 21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold DK0876393T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9526630.0A GB9526630D0 (en) 1995-12-29 1995-12-29 Compounds
GBGB9613036.4A GB9613036D0 (en) 1996-06-21 1996-06-21 Compounds
PCT/GB1996/003153 WO1997024367A1 (en) 1995-12-29 1996-12-19 21-(2-oxo-tetrahydrofuran)-thio pregnane derivatives, a process for their production and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DK0876393T3 true DK0876393T3 (da) 2000-11-06

Family

ID=26308399

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96943204T DK0876393T3 (da) 1995-12-29 1996-12-19 21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold

Country Status (12)

Country Link
US (1) US6013244A (da)
EP (1) EP0876393B1 (da)
JP (1) JP2947945B2 (da)
AT (1) ATE194357T1 (da)
AU (1) AU1200097A (da)
DE (1) DE69609201T2 (da)
DK (1) DK0876393T3 (da)
ES (1) ES2150151T3 (da)
GR (1) GR3034563T3 (da)
PT (1) PT876393E (da)
SI (1) SI0876393T1 (da)
WO (1) WO1997024367A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999001467A2 (en) * 1997-06-30 1999-01-14 Glaxo Group Limited Therapeutically active compounds with low systemic activity due to reduce half life
WO2004028545A1 (en) * 2002-09-25 2004-04-08 Astrazeneca Ab A COMBINATION OF A LONG-ACTING β2-AGONIST AND A GLUCOCORTICOSTEROID IN THE TREATMENT OF FIBROTIC DISEASES
WO2008124145A1 (en) * 2007-04-05 2008-10-16 Government Of The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Steroid compounds, compositions, and methods of treatment
CA2710240A1 (en) * 2007-12-21 2009-07-09 Schering Corporation C-21 thioethers as glucocorticoid receptor agonists
MX2011013679A (es) 2009-06-16 2012-01-20 Schering Corp Esteroides de heteroarilo [3.2-c] novedosos como agonistas de receptor de glucocorticoide composiciones y uso de los mismos.
WO2024125639A1 (zh) * 2022-12-16 2024-06-20 津药生物科技（天津）有限公司 新型糖皮质激素、其制备方法及用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420120A (en) * 1993-12-17 1995-05-30 Alcon Laboratories, Inc. Anti-inflammatory glucocorticoid compounds for topical ophthalmic use

Also Published As

Publication number Publication date
SI0876393T1 (en) 2000-12-31
JP2947945B2 (ja) 1999-09-13
GR3034563T3 (en) 2001-01-31
ATE194357T1 (de) 2000-07-15
EP0876393A1 (en) 1998-11-11
DE69609201D1 (de) 2000-08-10
WO1997024367A1 (en) 1997-07-10
ES2150151T3 (es) 2000-11-16
EP0876393B1 (en) 2000-07-05
DE69609201T2 (de) 2001-03-01
PT876393E (pt) 2000-12-29
AU1200097A (en) 1997-07-28
US6013244A (en) 2000-01-11
JPH11501676A (ja) 1999-02-09

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