DK0845005T3 - TRAF-inhibitorer - Google Patents

TRAF-inhibitorer

Info

Publication number
DK0845005T3
DK0845005T3 DK96927409T DK96927409T DK0845005T3 DK 0845005 T3 DK0845005 T3 DK 0845005T3 DK 96927409 T DK96927409 T DK 96927409T DK 96927409 T DK96927409 T DK 96927409T DK 0845005 T3 DK0845005 T3 DK 0845005T3
Authority
DK
Denmark
Prior art keywords
traf
inhibitors
trafs
pharmaceuticals
nucleic acid
Prior art date
Application number
DK96927409T
Other languages
English (en)
Inventor
Mike Rothe
David V Goeddel
Original Assignee
Genentech Inc
Tularik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Tularik Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK0845005T3 publication Critical patent/DK0845005T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK96927409T 1995-08-17 1996-08-14 TRAF-inhibitorer DK0845005T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US238295P 1995-08-17 1995-08-17
PCT/US1996/013129 WO1997007134A1 (en) 1995-08-17 1996-08-14 Traf inhibitors

Publications (1)

Publication Number Publication Date
DK0845005T3 true DK0845005T3 (da) 2005-08-01

Family

ID=21700513

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96927409T DK0845005T3 (da) 1995-08-17 1996-08-14 TRAF-inhibitorer

Country Status (13)

Country Link
US (6) US5789550A (da)
EP (2) EP0845005B1 (da)
JP (2) JP4382878B2 (da)
AT (1) ATE291585T1 (da)
AU (1) AU709535B2 (da)
CA (1) CA2227174A1 (da)
DE (1) DE69634512T2 (da)
DK (1) DK0845005T3 (da)
ES (1) ES2239334T3 (da)
IL (1) IL122980A0 (da)
NZ (1) NZ315514A (da)
WO (1) WO1997007134A1 (da)
ZA (1) ZA966663B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA966663B (en) * 1995-08-17 1998-02-06 Genentech Inc Traf Inhibitors.
EP0951551B9 (en) * 1996-12-23 2012-12-26 Immunex Corporation Ligand for receptor activator of nf-kappa b, ligand is member of tnf superfamily
US6271349B1 (en) 1996-12-23 2001-08-07 Immunex Corporation Receptor activator of NF-κB
US6723517B1 (en) * 1998-06-02 2004-04-20 Minerva Biotechnologies Corporation Use of self-assembled monolayers to probe the structure of a target molecule
AU4567299A (en) * 1998-06-22 2000-01-10 Feshchenko, Elena A. C-cbl suppression of neoplastic transformation
CA2385879A1 (en) * 1999-09-23 2001-03-29 Rigel Pharmaceuticals, Inc. Traf4 associated cell cycle proteins, compositions and methods of use
WO2002064786A1 (fr) * 2001-02-15 2002-08-22 Mochida Pharmaceutical Co., Ltd. Nouveau gene tcif
JP2005502598A (ja) * 2001-06-07 2005-01-27 メドベット・サイエンス・プロプライエタリー・リミテッド サイトカインを介する細胞活性を調節することによる治療方法およびそのために有用な物質
PT2087908T (pt) 2001-06-26 2018-07-16 Amgen Inc Anticorpos contra opgl
US20030083304A1 (en) * 2001-10-09 2003-05-01 Smart Robert C. CCAAT/enhancer binding protein-beta (C/EBPbeta) is a molecular target for cancer treatment
IL145918A0 (en) * 2001-10-14 2002-07-25 Ares Trading Sa Method and kit for monitoring recruitment of proteins to the intracellular domain of a receptor in intact cells
AU2003258036A1 (en) * 2002-08-01 2004-02-23 Wyeth Methods and reagents relating to inflammation and apoptosis
US20090182035A1 (en) * 2007-04-11 2009-07-16 Alcon Research, Ltd. Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
JP2010523695A (ja) * 2007-04-11 2010-07-15 アルコン リサーチ， リミテッド アレルギー性鼻炎およびアレルギー性結膜炎を処置するためのＴＮＦαのインヒビターおよび抗ヒスタミン薬の使用
US9486498B2 (en) * 2008-05-19 2016-11-08 Case Western Reserve University Method of treating CD40-mediated diseases
US10669345B2 (en) * 2008-05-19 2020-06-02 Case Western Reserve University Method for treating CD40-mediated diseases
KR20120101278A (ko) 2009-01-21 2012-09-13 버텍스 파마슈티칼스 인코포레이티드 Ｃ형 간염 바이러스 핵산을 증폭시키는 방법
MX2012003693A (es) * 2009-10-01 2012-04-19 Alcon Res Ltd Composiciones de olopatadine y usos de las mismas.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3613167A1 (de) * 1986-04-18 1987-10-29 Basf Ag Verwendung von tnf zur herstellung von arzneimitteln
US5108901A (en) 1988-09-02 1992-04-28 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
EP1132471A3 (de) * 1989-09-12 2001-11-28 F. Hoffmann-La Roche Ag TNF-bindende Proteine
US5318890A (en) 1991-05-06 1994-06-07 The Regents Of The University Of California Assays for inhibitors of leukocyte adhesion
JPH10512443A (ja) * 1994-12-30 1998-12-02 ブリガム アンド ウイメンズ ホスピタル Ｔｒａｆ−媒介シグナルの制御
ZA966663B (en) * 1995-08-17 1998-02-06 Genentech Inc Traf Inhibitors.

Also Published As

Publication number Publication date
US6060303A (en) 2000-05-09
EP1568708A2 (en) 2005-08-31
US6294348B1 (en) 2001-09-25
AU6723796A (en) 1997-03-12
JP2009065981A (ja) 2009-04-02
NZ315514A (en) 1998-12-23
ZA966663B (en) 1998-02-06
US20040087774A1 (en) 2004-05-06
DE69634512T2 (de) 2006-02-09
ATE291585T1 (de) 2005-04-15
DE69634512D1 (de) 2005-04-28
EP0845005B1 (en) 2005-03-23
AU709535B2 (en) 1999-09-02
US6063585A (en) 2000-05-16
EP0845005A1 (en) 1998-06-03
US6004553A (en) 1999-12-21
ES2239334T3 (es) 2005-09-16
US5789550A (en) 1998-08-04
WO1997007134A1 (en) 1997-02-27
JP4382878B2 (ja) 2009-12-16
MX9800995A (es) 1998-10-31
JPH11511967A (ja) 1999-10-19
EP1568708A3 (en) 2005-10-12
IL122980A0 (en) 1998-08-16
CA2227174A1 (en) 1997-02-27

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