DK0787135T3 - Vandopløslige derivater af epipodophyllotoxin, fremgangsmåde til fremstilling deraf og anvendelse som et lægemiddel til beh - Google Patents

Vandopløslige derivater af epipodophyllotoxin, fremgangsmåde til fremstilling deraf og anvendelse som et lægemiddel til beh

Info

Publication number
DK0787135T3
DK0787135T3 DK95935993T DK95935993T DK0787135T3 DK 0787135 T3 DK0787135 T3 DK 0787135T3 DK 95935993 T DK95935993 T DK 95935993T DK 95935993 T DK95935993 T DK 95935993T DK 0787135 T3 DK0787135 T3 DK 0787135T3
Authority
DK
Denmark
Prior art keywords
epipodophyllotoxin
preparation
treatment
pct
soluble derivatives
Prior art date
Application number
DK95935993T
Other languages
English (en)
Inventor
Thierry Imbert
Yves Guminski
Barbara Monse
Bridget Hill
Jean-Pierre Robin
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Application granted granted Critical
Publication of DK0787135T3 publication Critical patent/DK0787135T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK95935993T 1994-10-21 1995-10-20 Vandopløslige derivater af epipodophyllotoxin, fremgangsmåde til fremstilling deraf og anvendelse som et lægemiddel til beh DK0787135T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9412597A FR2725990B1 (fr) 1994-10-21 1994-10-21 Derives hydrosolubles d'epipodophyllotoxine, leur procede de preparation, leur utilisation a titre de medicament, et leur utilisation destinee aux traitements anticancereux
PCT/FR1995/001388 WO1996012727A1 (fr) 1994-10-21 1995-10-20 Derives hydrosolubles d'epipodophyllotoxine, leur procede de preparation, leur utilisation a titre de medicament, et leur utilisation destinee aux traitements anticancereux

Publications (1)

Publication Number Publication Date
DK0787135T3 true DK0787135T3 (da) 2000-10-23

Family

ID=9468081

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95935993T DK0787135T3 (da) 1994-10-21 1995-10-20 Vandopløslige derivater af epipodophyllotoxin, fremgangsmåde til fremstilling deraf og anvendelse som et lægemiddel til beh

Country Status (13)

Country Link
US (1) US6107284A (da)
EP (1) EP0787135B1 (da)
JP (1) JPH10507462A (da)
AT (1) ATE193297T1 (da)
AU (1) AU705248B2 (da)
DE (1) DE69517191T2 (da)
DK (1) DK0787135T3 (da)
ES (1) ES2148572T3 (da)
FR (1) FR2725990B1 (da)
GR (1) GR3034155T3 (da)
NZ (1) NZ294878A (da)
PT (1) PT787135E (da)
WO (1) WO1996012727A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2791682B1 (fr) * 1999-03-29 2001-06-22 Pf Medicament Procede de preparation du 4'-demethyl-4'-phosphate-2", 3"-bis pentafluorophenoxyacetyl-4",6"-ethyldidene-beta-d- glucoside d'epipodophyllotoxine, et de ses sels
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
DE60135732D1 (de) * 2000-02-28 2008-10-23 Univ British Columbia Topoisomerasehemmern zur behandlung von chirurgischen verklebungen
SE0002045D0 (sv) * 2000-05-31 2000-05-31 Sahltech Ab New use
FR2830760B1 (fr) * 2001-10-12 2004-06-04 Pf Medicament Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique
FR2854079B1 (fr) 2003-04-25 2007-11-30 Pf Medicament Procede de preparation de complexes moleculaires
FR2859724B1 (fr) * 2003-09-16 2005-12-30 Pf Medicament Compose cristallin sous forme libre ou hemiethanolate de 4'-demethyl-4'-phosphate-2",3"-bispentafluorophenoxyacetyl- 4",6"-ethylidene-beta-d-glucoside d'epipodophyllotoxine
FR2869035B1 (fr) * 2004-04-16 2006-07-14 Pierre Fabre Medicament Sa Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux
AU2011274229A1 (en) 2010-07-02 2013-01-10 Angiochem Inc. Short and D-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
CN102070645B (zh) * 2011-01-07 2015-04-22 兰州大学 一种脱氧鬼臼毒素类化合物及其制备与应用
WO2023092188A1 (en) * 2021-11-26 2023-06-01 DemAgtech Pty Ltd "compounds and methods"

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US5066645A (en) * 1989-09-01 1991-11-19 Bristol-Myers Company Epipodophyllotoxin altroside derivatives
FR2658824B1 (fr) * 1990-02-27 1992-07-03 Pf Medicament Tris acetyl-2",3",4' ethylidene-4",6" beta-d-glucopyranosides, leur preparation et leur utilisation pour la preparation d'ethylidene beta-d-glucopyranoside de demethyl-4' epipodophyllotoxine.
FR2699535B1 (fr) * 1992-12-22 1995-03-17 Pf Medicament Dérivés de l'étoposide, leur procédé de préparation, leur utilisation à titre de médicament et leur utilisation pour la préparation d'un médicament destiné au traitement anticancéreux.

Also Published As

Publication number Publication date
NZ294878A (en) 1998-10-28
EP0787135B1 (fr) 2000-05-24
WO1996012727A1 (fr) 1996-05-02
FR2725990B1 (fr) 1997-01-10
AU705248B2 (en) 1999-05-20
ATE193297T1 (de) 2000-06-15
PT787135E (pt) 2000-11-30
FR2725990A1 (fr) 1996-04-26
JPH10507462A (ja) 1998-07-21
ES2148572T3 (es) 2000-10-16
DE69517191D1 (de) 2000-06-29
EP0787135A1 (fr) 1997-08-06
US6107284A (en) 2000-08-22
DE69517191T2 (de) 2001-02-15
GR3034155T3 (en) 2000-11-30
AU3808795A (en) 1996-05-15

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