DK0776325T3 - Ny anvendelse af og nye imidazolderivater, fremgangsmåde til deres fremstilling, nye mellemprodukter deraf, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf - Google Patents

Ny anvendelse af og nye imidazolderivater, fremgangsmåde til deres fremstilling, nye mellemprodukter deraf, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf

Info

Publication number: DK0776325T3
Authority: DK; Denmark
Prior art keywords: new; pct; alkenyl; alkyl; pharmaceuticals
Prior art date: 1994-08-02

Application number

DK95927004T

Other languages

English (en)

Inventor

Bertrand Heckmann

Jean-Paul Vevert

Jidong Zhang

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-02

Filing date

1995-08-01

Publication date

2003-03-17

1995-08-01 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2003-03-17 Application granted granted Critical

2003-03-17 Publication of DK0776325T3 publication Critical patent/DK0776325T3/da

Links

239000003814 drug Substances 0.000 title abstract 2
150000002460 imidazoles Chemical class 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000003342 alkenyl group Chemical group 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
125000000304 alkynyl group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
-1 carboxy, nitro, cyano, amino, carbamoyl Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000003107 substituted aryl group Chemical group 0.000 abstract 1
125000003396 thiol group Chemical class [H]S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Nutrition Science (AREA)
Vascular Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK95927004T 1994-08-02 1995-08-01 Ny anvendelse af og nye imidazolderivater, fremgangsmåde til deres fremstilling, nye mellemprodukter deraf, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf DK0776325T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9409566A FR2723370B1 (fr)	1994-08-02	1994-08-02	Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
PCT/FR1995/001034 WO1996004276A1 (fr)	1994-08-02	1995-08-01	Nouvelle utilisation et nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number	Publication Date
DK0776325T3 true DK0776325T3 (da)	2003-03-17

Family

ID=9465986

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95927004T DK0776325T3 (da)	1994-08-02	1995-08-01	Ny anvendelse af og nye imidazolderivater, fremgangsmåde til deres fremstilling, nye mellemprodukter deraf, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf

Country Status (20)

Country	Link
US (1)	US5811444A (da)
EP (1)	EP0776325B1 (da)
JP (1)	JP4044134B2 (da)
CN (1)	CN1082961C (da)
AT (1)	ATE228127T1 (da)
AU (1)	AU707927B2 (da)
BR (1)	BR9508481A (da)
CA (1)	CA2196218A1 (da)
DE (1)	DE69528902T2 (da)
DK (1)	DK0776325T3 (da)
ES (1)	ES2182909T3 (da)
FI (1)	FI970424A (da)
FR (1)	FR2723370B1 (da)
HU (1)	HU221464B (da)
IL (1)	IL114753A0 (da)
MX (1)	MX9700821A (da)
PT (1)	PT776325E (da)
RU (1)	RU2187507C2 (da)
WO (1)	WO1996004276A1 (da)
ZA (1)	ZA956453B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2740773B1 (fr) *	1995-11-08	1997-12-19	Roussel Uclaf	Nouveaux derives de l'imidazole, procede de preparation, intermediaires obtenus, application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
FR2740774B1 (fr) *	1995-11-08	1997-12-19	Roussel Uclaf	Nouveaux derives d'imidazole n-benzyldioxole, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
FR2831822A1 (fr) *	2001-11-07	2003-05-09	Inst Nat Sante Rech Med	Utilisation therapeutique de derives 4-mercapto- ou 4-seleno-imidazoles
CA2863994C (en) *	2012-02-16	2020-06-16	Dow Agrosciences Llc	Methods of producing sulfilimine compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2862340D1 (en) *	1978-02-01	1983-11-24	Wellcome Found	Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
WO1994002474A1 (en) *	1992-07-17	1994-02-03	Smithkline Beecham Corporation	Endothelin receptor antagonists
US5559105A (en) *	1992-07-17	1996-09-24	Smithkline Beecham Corporation	Endothelin receptor antagonists

1994
- 1994-08-02 FR FR9409566A patent/FR2723370B1/fr not_active Expired - Fee Related
1995
- 1995-07-27 IL IL11475395A patent/IL114753A0/xx unknown
- 1995-08-01 US US08/776,953 patent/US5811444A/en not_active Expired - Fee Related
- 1995-08-01 HU HU9700295A patent/HU221464B/hu not_active IP Right Cessation
- 1995-08-01 MX MX9700821A patent/MX9700821A/es unknown
- 1995-08-01 JP JP50626196A patent/JP4044134B2/ja not_active Expired - Fee Related
- 1995-08-01 ES ES95927004T patent/ES2182909T3/es not_active Expired - Lifetime
- 1995-08-01 CA CA002196218A patent/CA2196218A1/fr not_active Abandoned
- 1995-08-01 AT AT95927004T patent/ATE228127T1/de not_active IP Right Cessation
- 1995-08-01 CN CN95195205A patent/CN1082961C/zh not_active Expired - Fee Related
- 1995-08-01 BR BR9508481A patent/BR9508481A/pt not_active Application Discontinuation
- 1995-08-01 WO PCT/FR1995/001034 patent/WO1996004276A1/fr active IP Right Grant
- 1995-08-01 PT PT95927004T patent/PT776325E/pt unknown
- 1995-08-01 DK DK95927004T patent/DK0776325T3/da active
- 1995-08-01 AU AU31179/95A patent/AU707927B2/en not_active Ceased
- 1995-08-01 RU RU97103193/04A patent/RU2187507C2/ru not_active IP Right Cessation
- 1995-08-01 EP EP95927004A patent/EP0776325B1/fr not_active Expired - Lifetime
- 1995-08-01 DE DE69528902T patent/DE69528902T2/de not_active Expired - Fee Related
- 1995-08-02 ZA ZA956453A patent/ZA956453B/xx unknown
1997
- 1997-01-31 FI FI970424A patent/FI970424A/fi unknown

Also Published As

Publication number	Publication date
BR9508481A (pt)	1997-09-30
HU221464B (en)	2002-10-28
FR2723370B1 (fr)	1996-09-13
WO1996004276A1 (fr)	1996-02-15
AU707927B2 (en)	1999-07-22
JP4044134B2 (ja)	2008-02-06
ES2182909T3 (es)	2003-03-16
CN1158613A (zh)	1997-09-03
PT776325E (pt)	2003-03-31
FI970424A (fi)	1997-04-01
CN1082961C (zh)	2002-04-17
DE69528902D1 (de)	2003-01-02
DE69528902T2 (de)	2003-04-10
CA2196218A1 (fr)	1996-02-15
RU2187507C2 (ru)	2002-08-20
FR2723370A1 (fr)	1996-02-09
HUT77767A (hu)	1998-08-28
IL114753A0 (en)	1995-11-27
ATE228127T1 (de)	2002-12-15
US5811444A (en)	1998-09-22
EP0776325B1 (fr)	2002-11-20
EP0776325A1 (fr)	1997-06-04
JPH10504544A (ja)	1998-05-06
FI970424A0 (fi)	1997-01-31
MX9700821A (es)	1997-05-31
ZA956453B (en)	1996-08-05
AU3117995A (en)	1996-03-04

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ATE148108T1 (de)	1997-02-15	Beta,beta-dimethyl-4-piperidinethanamin-derivat als inhibitoren der cholesterin-biosynthese
ZA9610418B (en)	1997-12-11	Phenylimidazolidines containing in particular a nitrooxy or carbonyloxy radical, preparation process and intermediates, use as medicaments, new uses and pharmaceutical compositions.
DE69231445D1 (de)	2000-10-19	Triazole enthaltende antifungizide mittel
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DK0678089T3 (da)	1996-11-18	N-Acylpyrrolidiner og lægemidler til behandling eller forebyggelse af cholecystokinin- og gastrin-relaterede forstyrrelser
DK0706517T3 (da)	1999-06-28	Pyridazinonderivater med farmaceutisk virkning
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SE9704835D0 (sv)	1997-12-22	New compound