DK0763024T3 - Fremgangmåde og mellemprodukter til fremstilling af piperazinderivater - Google Patents
Fremgangmåde og mellemprodukter til fremstilling af piperazinderivaterInfo
- Publication number
- DK0763024T3 DK0763024T3 DK95921010T DK95921010T DK0763024T3 DK 0763024 T3 DK0763024 T3 DK 0763024T3 DK 95921010 T DK95921010 T DK 95921010T DK 95921010 T DK95921010 T DK 95921010T DK 0763024 T3 DK0763024 T3 DK 0763024T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- compounds
- piperazine derivatives
- intermediates
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9411108A GB9411108D0 (en) | 1994-06-03 | 1994-06-03 | Novel processes and intermediates for the preparation of piperazine derivatives |
GBGB9510152.3A GB9510152D0 (en) | 1995-05-19 | 1995-05-19 | Process for the preparation of piperazine intermediates |
PCT/GB1995/001256 WO1995033725A1 (en) | 1994-06-03 | 1995-06-01 | Novel processes and intermediates for the preparation of piperazine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0763024T3 true DK0763024T3 (da) | 2002-12-02 |
Family
ID=26304996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95921010T DK0763024T3 (da) | 1994-06-03 | 1995-06-01 | Fremgangmåde og mellemprodukter til fremstilling af piperazinderivater |
Country Status (12)
Country | Link |
---|---|
US (3) | US6175012B1 (da) |
EP (1) | EP0763024B1 (da) |
JP (1) | JPH10504275A (da) |
AT (1) | ATE222238T1 (da) |
AU (1) | AU2622595A (da) |
CA (1) | CA2191874C (da) |
DE (1) | DE69527787T2 (da) |
DK (1) | DK0763024T3 (da) |
ES (1) | ES2180638T3 (da) |
IL (1) | IL113966A (da) |
PT (1) | PT763024E (da) |
WO (1) | WO1995033725A1 (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0763024T3 (da) * | 1994-06-03 | 2002-12-02 | Wyeth John & Brother Ltd | Fremgangmåde og mellemprodukter til fremstilling af piperazinderivater |
GB9514901D0 (en) * | 1995-07-20 | 1995-09-20 | American Home Prod | Piperazine derivatives |
CZ8197A3 (en) | 1996-01-16 | 1997-10-15 | American Home Prod | (1h-indol-4-yl)-piperidine- or tetrahydropyridine ethyl amines and -ethyl carboxamides and pharmaceutical composition containing thereof |
US6271234B1 (en) * | 1997-08-01 | 2001-08-07 | Recordati S.A., Chemical And Pharmaceutical Company | 1,4-disubstituted piperazines |
US20060287335A1 (en) | 2000-11-28 | 2006-12-21 | Wyeth | Serotonergic agents for treating sexual dysfunction |
US20060223824A1 (en) | 2000-11-28 | 2006-10-05 | Wyeth | Serotonergic agents |
RU2315044C2 (ru) | 2002-03-12 | 2008-01-20 | Уайт | Способ получения хиральных 1,4-дизамещенных пиперазинов |
KR20040091720A (ko) * | 2002-03-12 | 2004-10-28 | 와이어쓰 | N1-(2'-피리딜)-1,2-프로판디아민 설팜산의 제조방법 및생물학적 활성 피페라진 합성시의 이의 용도 |
US7361773B2 (en) | 2002-03-12 | 2008-04-22 | Wyeth | Preparation of N1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines |
US7091349B2 (en) | 2002-03-12 | 2006-08-15 | Wyeth | Process for synthesizing N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane substitution |
MXPA04008729A (es) | 2002-03-12 | 2005-07-13 | Wyeth Corp | Proceso para sintetizacion de piperazinas n-arilicas quirales. |
PA8626301A1 (es) * | 2004-03-19 | 2006-12-07 | Wyeth Wyeth | Proceso para preparar derivados de n-aril-piperazina |
GB2454136B (en) * | 2006-09-12 | 2011-11-30 | Jubilant Organosys Ltd | Eco-friendly process for recovery of pyridine and/or its derivatives |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3405859A1 (de) * | 1984-02-18 | 1985-08-22 | Basf Ag, 6700 Ludwigshafen | Sulfongruppenhaltige azoverbindungen |
DE3685840D1 (de) * | 1985-04-30 | 1992-08-06 | Dresden Arzneimittel | 3-cyan-pyridine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. |
GB8512163D0 (en) | 1985-05-14 | 1985-06-19 | Fujisawa Pharmaceutical Co | Oxothiazolidine compound |
US4741831A (en) * | 1986-12-04 | 1988-05-03 | The Dow Chemical Company | Process and composition for removal of metal ions from aqueous solutions |
DE68923534T2 (de) * | 1988-11-05 | 1996-01-04 | Sumitomo Electric Industries | Verfahren zur Herstellung eines organischen Kristalls. |
DE4042005A1 (de) | 1990-12-22 | 1992-06-25 | Schering Ag | D-homo-(16-en)-11(beta)-aryl-4-estrene |
US5342953A (en) | 1991-01-31 | 1994-08-30 | Syntex (U.S.A.) Inc. | N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom |
MX9201991A (es) * | 1991-05-02 | 1992-11-01 | Jonh Wyeth & Brother Limited | Derivados de piperazina y procedimiento para su preparacion. |
US5271812A (en) * | 1991-06-19 | 1993-12-21 | Sepracor, Inc. | Electrocatalytic oxidation method for the production of cyclic sulfates and sulfamidates |
GB9314758D0 (en) * | 1993-07-16 | 1993-08-25 | Wyeth John & Brother Ltd | Heterocyclic derivatives |
GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
DK0763024T3 (da) * | 1994-06-03 | 2002-12-02 | Wyeth John & Brother Ltd | Fremgangmåde og mellemprodukter til fremstilling af piperazinderivater |
US5439915A (en) * | 1994-10-20 | 1995-08-08 | American Home Products Corporation | Pyrido[3,4-B]indole carboxamide derivatives as serotonergic agents |
US5541179A (en) * | 1995-05-02 | 1996-07-30 | American Home Products Corporation | Tropon-2-one piperazine carboxamides as serotonergic agents |
-
1995
- 1995-06-01 DK DK95921010T patent/DK0763024T3/da active
- 1995-06-01 EP EP95921010A patent/EP0763024B1/en not_active Expired - Lifetime
- 1995-06-01 ES ES95921010T patent/ES2180638T3/es not_active Expired - Lifetime
- 1995-06-01 CA CA002191874A patent/CA2191874C/en not_active Expired - Fee Related
- 1995-06-01 JP JP8500527A patent/JPH10504275A/ja active Pending
- 1995-06-01 IL IL11396695A patent/IL113966A/xx not_active IP Right Cessation
- 1995-06-01 AT AT95921010T patent/ATE222238T1/de not_active IP Right Cessation
- 1995-06-01 WO PCT/GB1995/001256 patent/WO1995033725A1/en active IP Right Grant
- 1995-06-01 PT PT95921010T patent/PT763024E/pt unknown
- 1995-06-01 AU AU26225/95A patent/AU2622595A/en not_active Abandoned
- 1995-06-01 DE DE69527787T patent/DE69527787T2/de not_active Expired - Fee Related
-
1998
- 1998-01-22 US US09/010,741 patent/US6175012B1/en not_active Expired - Fee Related
- 1998-01-22 US US09/012,066 patent/US6133449A/en not_active Expired - Fee Related
-
2000
- 2000-07-12 US US09/614,792 patent/US6395902B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69527787T2 (de) | 2003-01-02 |
ES2180638T3 (es) | 2003-02-16 |
DE69527787D1 (de) | 2002-09-19 |
JPH10504275A (ja) | 1998-04-28 |
US6395902B1 (en) | 2002-05-28 |
PT763024E (pt) | 2002-11-29 |
US6175012B1 (en) | 2001-01-16 |
US6133449A (en) | 2000-10-17 |
IL113966A (en) | 2000-08-13 |
CA2191874C (en) | 2008-05-20 |
AU2622595A (en) | 1996-01-04 |
EP0763024B1 (en) | 2002-08-14 |
ATE222238T1 (de) | 2002-08-15 |
EP0763024A1 (en) | 1997-03-19 |
CA2191874A1 (en) | 1995-12-14 |
WO1995033725A1 (en) | 1995-12-14 |
IL113966A0 (en) | 1995-10-31 |
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