DK0701815T3 - Fremgangsmåde til fremstilling af aktivstofholdige pulvere, granulater eller pellets med en grundstruktur af hydrofile makr - Google Patents

Fremgangsmåde til fremstilling af aktivstofholdige pulvere, granulater eller pellets med en grundstruktur af hydrofile makr

Info

Publication number
DK0701815T3
DK0701815T3 DK95113398T DK95113398T DK0701815T3 DK 0701815 T3 DK0701815 T3 DK 0701815T3 DK 95113398 T DK95113398 T DK 95113398T DK 95113398 T DK95113398 T DK 95113398T DK 0701815 T3 DK0701815 T3 DK 0701815T3
Authority
DK
Denmark
Prior art keywords
hydrophilic
macar
pellets
granules
preparation
Prior art date
Application number
DK95113398T
Other languages
English (en)
Inventor
Ursula Schick
Juergen Werry
Juergen Freidenreich
Jens-Christian Wunderlich
Original Assignee
Alfatec Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27435369&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0701815(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE4201173A external-priority patent/DE4201173C2/de
Priority claimed from DE4201179A external-priority patent/DE4201179A1/de
Application filed by Alfatec Pharma Gmbh filed Critical Alfatec Pharma Gmbh
Application granted granted Critical
Publication of DK0701815T3 publication Critical patent/DK0701815T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/022—Powders; Compacted Powders
    • A61K8/0225—Granulated powders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Glanulating (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
DK95113398T 1992-01-17 1993-01-18 Fremgangsmåde til fremstilling af aktivstofholdige pulvere, granulater eller pellets med en grundstruktur af hydrofile makr DK0701815T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4201173A DE4201173C2 (de) 1992-01-17 1992-01-17 Akutarzneimittel in Form von Dihydropyridinderivaten enthaltenden Pellets und ihre Herstellung
DE4201179A DE4201179A1 (de) 1992-01-17 1992-01-17 Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung
US07/876,877 US5384129A (en) 1992-01-17 1992-04-30 Pellets containing dihydropyridine derivatives process for the production thereof and use as rapid action dosage in heart and circulatory diseases
US07/876,864 US5405616A (en) 1992-01-17 1992-04-30 Means for containing active substances, having a shell of hydrophilic macromolecules, active substances and process for preparation thereof

Publications (1)

Publication Number Publication Date
DK0701815T3 true DK0701815T3 (da) 2000-02-07

Family

ID=27435369

Family Applications (2)

Application Number Title Priority Date Filing Date
DK95113398T DK0701815T3 (da) 1992-01-17 1993-01-18 Fremgangsmåde til fremstilling af aktivstofholdige pulvere, granulater eller pellets med en grundstruktur af hydrofile makr
DK93902034.3T DK0621777T3 (da) 1992-01-17 1993-01-18 Pellets indeholdende aktivt stof og med en matrix af hydrofile makromolekyler, og fremgangsmåde til deres fremstilling

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK93902034.3T DK0621777T3 (da) 1992-01-17 1993-01-18 Pellets indeholdende aktivt stof og med en matrix af hydrofile makromolekyler, og fremgangsmåde til deres fremstilling

Country Status (10)

Country Link
EP (2) EP0621777B1 (da)
JP (1) JPH07502736A (da)
AT (2) ATE142484T1 (da)
AU (1) AU679906B2 (da)
CA (1) CA2128244C (da)
DE (2) DE59309678D1 (da)
DK (2) DK0701815T3 (da)
ES (2) ES2133633T3 (da)
GR (2) GR3021223T3 (da)
WO (1) WO1993013757A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2714575B1 (fr) * 1994-01-03 1996-02-02 Rhone Poulenc Nutrition Animal Nouveaux granulés contenant des organismes vivant pour l'alimentation animale.
SE9704401D0 (sv) 1997-11-28 1997-11-28 Astra Ab Matrix pellets for greasy, oily or sticky drug substances
EP1243318B1 (de) * 2001-03-22 2005-03-02 Cognis Iberia, S.L. Mikrokapseln (VII)
US6713452B2 (en) 2001-06-04 2004-03-30 Nobex Corporation Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
US6828297B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828305B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6835802B2 (en) 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
FR2843302B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
FR2843301B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
ES2529568T3 (es) * 2002-10-16 2015-02-23 Medskin Solutions Dr. Suwelack Ag Uso de cuerpos moldeados para aplicación externa
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
EP2626368B1 (en) 2004-07-19 2016-12-21 Biocon Limited Insulin-oligomer conjugates, formulations and uses thereof
FR2887455B1 (fr) * 2005-06-28 2007-08-10 Sanofi Aventis Sa Formulation a liberation prolongee de principes actifs de medicaments
US9308175B2 (en) 2006-09-15 2016-04-12 Echo Pharmaceuticals B.V. Dosage unit for sublingual, buccal or oral administration of water-insoluble pharmaceutically active substances
ATE516796T1 (de) * 2006-09-15 2011-08-15 Echo Pharmaceuticals Bv Granulat mit einem pharmazeutischen wirkstoff und einem emulgator und herstellungsverfahren dafür
US8273376B2 (en) 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
CN101904813A (zh) 2009-04-22 2010-12-08 苏维拉克皮肤及健康护理公司 冻干包衣的模制品
AU2013296803B2 (en) * 2012-08-01 2018-03-08 Eric Ostertag Free flowing, frozen compositions comprising a therapeutic agent
ITMI20122145A1 (it) * 2012-12-14 2014-06-15 Velleja Res Srl Composizioni per uso orale contenenti idrolizzati di collagene, di elastina e vitamina c favorenti la deposizione di matrice extra-cellulare
LU102656B1 (de) 2021-03-11 2022-09-12 Prosecur Gmbh Flüssiges Nahrungsergänzungsmittel zur Immunstimulation, Verfahren zu dessen Herstellung sowie Verwendung

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1248863B (da) * 1959-01-30
GB887901A (da) * 1960-04-13 1900-01-01
IE53696B1 (en) * 1981-12-02 1989-01-18 Wyeth John & Brother Ltd Solid shaped articles
DE3486029T2 (de) * 1983-10-14 1993-05-13 Sumitomo Pharma Ifn-praeparat mit verzoegerter abgabe fuer parentale verabreichung.
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
FR2634121B1 (fr) * 1988-07-13 1992-05-07 Imedex Procede de preparation de microparticules de collagene et produits obtenus
JPH02135052A (ja) * 1988-11-17 1990-05-23 Taiyo Kagaku Co Ltd 粒状食品の製造方法
US5007790A (en) * 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
FR2650502B1 (fr) * 1989-08-07 1994-05-27 Delagrange Laboratoires Nouvelle forme galenique orale ameliorant la biodisponibilite
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
EP0620727B1 (de) 1992-01-17 1997-04-16 ALFATEC-PHARMA GmbH Pflanzenwirkstoffextrakt enthaltende kryopelletierte formkörper und ihre pharmazeutische oder kosmetische verwendung
AU3343093A (en) 1992-01-17 1993-08-03 Alfatec-Pharma Gmbh Pellets containing peptide drugs, their manufacture and use
DE59301262D1 (de) 1992-01-17 1996-02-08 Alfatec Pharma Gmbh Verfahren zur herstellung von weichgelatinekapseln nach einem tropfverfahren
DE4221880A1 (de) * 1992-07-03 1994-01-05 Alfatec Pharma Gmbh Feste und flüssige Lösungen von schwer wasserlöslichen Arzneistoffen

Also Published As

Publication number Publication date
EP0701815A1 (de) 1996-03-20
ES2092808T3 (es) 1996-12-01
CA2128244A1 (en) 1993-07-22
EP0701815B1 (de) 1999-06-30
EP0621777B1 (de) 1996-09-11
DE59303759C5 (de) 2009-04-09
ATE181666T1 (de) 1999-07-15
EP0621777A1 (de) 1994-11-02
DE59309678D1 (de) 1999-08-05
JPH07502736A (ja) 1995-03-23
GR3021223T3 (en) 1997-01-31
CA2128244C (en) 1998-09-22
GR3030675T3 (en) 1999-11-30
ES2133633T3 (es) 1999-09-16
AU679906B2 (en) 1997-07-17
DE59303759D1 (de) 1996-10-17
ATE142484T1 (de) 1996-09-15
DK0621777T3 (da) 1996-10-21
WO1993013757A1 (de) 1993-07-22
AU3343293A (en) 1993-08-03

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