DK0691980T3 - 7-deazapurinmodifiderende oligonukleotider - Google Patents

7-deazapurinmodifiderende oligonukleotider

Info

Publication number
DK0691980T3
DK0691980T3 DK94913923.2T DK94913923T DK0691980T3 DK 0691980 T3 DK0691980 T3 DK 0691980T3 DK 94913923 T DK94913923 T DK 94913923T DK 0691980 T3 DK0691980 T3 DK 0691980T3
Authority
DK
Denmark
Prior art keywords
deazapurine
oligonucleotides
modifying oligonucleotides
modifying
deazanucleosides
Prior art date
Application number
DK94913923.2T
Other languages
English (en)
Inventor
Daniel J Delecki
Phillip D Cook
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of DK0691980T3 publication Critical patent/DK0691980T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Communicable Diseases (AREA)
  • Saccharide Compounds (AREA)
DK94913923.2T 1993-03-30 1994-03-21 7-deazapurinmodifiderende oligonukleotider DK0691980T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4015893A 1993-03-30 1993-03-30

Publications (1)

Publication Number Publication Date
DK0691980T3 true DK0691980T3 (da) 1997-12-29

Family

ID=21909441

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94913923.2T DK0691980T3 (da) 1993-03-30 1994-03-21 7-deazapurinmodifiderende oligonukleotider

Country Status (11)

Country Link
EP (1) EP0691980B1 (da)
JP (1) JPH08508493A (da)
AT (1) ATE154029T1 (da)
AU (1) AU6589094A (da)
CA (1) CA2159630A1 (da)
DE (1) DE69403642T2 (da)
DK (1) DK0691980T3 (da)
ES (1) ES2105698T3 (da)
GR (1) GR3024597T3 (da)
HU (1) HU9501963D0 (da)
WO (1) WO1994022892A1 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4438918A1 (de) 1994-11-04 1996-05-09 Hoechst Ag Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung
US6150510A (en) 1995-11-06 2000-11-21 Aventis Pharma Deutschland Gmbh Modified oligonucleotides, their preparation and their use
US6906185B1 (en) 1997-03-20 2005-06-14 Amersham Biosciences Corp. Derivatives of 7-deaza -2′-deoxyguanosine-5'-triphosphate, preparation and use thereof
GB2323357B (en) * 1997-03-20 1999-09-29 Amersham Pharm Biotech Inc Derivatives of 7-deaza-2-deoxy-guanosine-5'-triphosphate, preparation and use thereof
US6660845B1 (en) * 1999-11-23 2003-12-09 Epoch Biosciences, Inc. Non-aggregating, non-quenching oligomers comprising nucleotide analogues; methods of synthesis and use thereof
US6962906B2 (en) 2000-03-14 2005-11-08 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
WO2001068673A1 (en) 2000-03-14 2001-09-20 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
US7262286B2 (en) * 2000-09-26 2007-08-28 Idera Pharmaceuticals, Inc. Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
CA2691364C (en) 2007-06-19 2020-06-16 Stratos Genomics, Inc. High throughput nucleic acid sequencing by expansion
CN102365367A (zh) 2009-01-29 2012-02-29 斯特拉托斯基因公司 通过展开进行高通量核酸测序和相关方法
WO2012003330A2 (en) 2010-06-30 2012-01-05 Stratos Genomics, Inc Multiplexed identification of nucleic acid sequences
US9212392B2 (en) 2012-09-25 2015-12-15 Exact Sciences Corporation Normalization of polymerase activity
US20140287946A1 (en) 2013-03-14 2014-09-25 Ibis Biosciences, Inc. Nucleic acid control panels
AU2015349730C1 (en) 2014-11-20 2020-04-30 F. Hoffmann-La Roche Ag Nulceoside phosphoroamidate esters and derivatives thereof, use and synthesis thereof
US10704081B2 (en) 2015-10-30 2020-07-07 Exact Sciences Development Company, Llc Multiplex amplification detection assay
EP3377648B1 (en) 2015-11-16 2021-01-06 Stratos Genomics, Inc. Dp04 polymerase variants
CN116064796A (zh) 2016-05-05 2023-05-05 精密科学公司 通过分析甲基化dna来检测肺肿瘤
US11118228B2 (en) 2017-01-27 2021-09-14 Exact Sciences Development Company, Llc Detection of colon neoplasia by analysis of methylated DNA
WO2018155450A1 (ja) 2017-02-21 2018-08-30 国立大学法人大阪大学 アンチセンスオリゴ核酸
WO2018204707A1 (en) 2017-05-04 2018-11-08 Stratos Genomics Inc. Dp04 polymerase variants
JP7288457B2 (ja) 2017-12-11 2023-06-07 ストラトス ゲノミクス インコーポレイテッド 正確性が向上したｄｐｏ４ポリメラーゼバリアント
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
US20220403450A1 (en) 2021-06-03 2022-12-22 Illumina Software, Inc. Systems and methods for sequencing nucleotides using two optical channels
CA3223131A1 (en) 2021-07-01 2023-01-05 Rean Silke MUSA Device having horizontal nanochannel for nanopore sequencing
WO2023034079A1 (en) 2021-09-01 2023-03-09 Illumina Software, Inc. Amplitude modulation for accelerated base calling
AU2022349615A1 (en) 2021-09-22 2024-01-18 Illumina, Inc. Sequencing polynucleotides using nanopores
US20230112203A1 (en) 2021-09-30 2023-04-13 Illumina, Inc. Isolation of cells in a nanopore sensor array
WO2023086391A1 (en) 2021-11-15 2023-05-19 Illumina, Inc. Nanopore systems and methods of fabrication
US20230183799A1 (en) 2021-12-10 2023-06-15 Illumina, Inc. Parallel sample and index sequencing
WO2023175026A1 (en) 2022-03-15 2023-09-21 Illumina, Inc. Methods of determining sequence information
US20230357307A1 (en) 2022-05-04 2023-11-09 Illumina, Inc. Cleavable cyclic loop nucleotides for nanopore sequencing
WO2023239660A1 (en) 2022-06-07 2023-12-14 Illumina Software, Inc. Methods and systems for identifying gene variants
WO2024010812A2 (en) 2022-07-07 2024-01-11 Illumina Software, Inc. Methods and systems for determining copy number variant genotypes
WO2024010809A2 (en) 2022-07-07 2024-01-11 Illumina Software, Inc. Methods and systems for detecting recombination events
WO2024073278A1 (en) 2022-09-26 2024-04-04 Illumina, Inc. Detecting and genotyping variable number tandem repeats
WO2024072685A1 (en) 2022-09-28 2024-04-04 Illumina, Inc. Fast pulsing for nanopore sensors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3739366A1 (de) * 1987-04-10 1988-10-27 Boehringer Mannheim Gmbh Desaza-purin-nucleosid-derivate, verfahren zu deren herstellung sowie deren verwendung bei der nucleinsaeure-sequenzierung sowie als antivirale mittel

Also Published As

Publication number Publication date
AU6589094A (en) 1994-10-24
DE69403642T2 (de) 1998-01-08
ES2105698T3 (es) 1997-10-16
HU9501963D0 (en) 1995-08-28
CA2159630A1 (en) 1994-10-13
GR3024597T3 (en) 1997-12-31
ATE154029T1 (de) 1997-06-15
WO1994022892A1 (en) 1994-10-13
DE69403642D1 (de) 1997-07-10
JPH08508493A (ja) 1996-09-10
EP0691980A1 (en) 1996-01-17
EP0691980B1 (en) 1997-06-04

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