DK0680321T3 - Lysinsalt af 6-chlor-5-fluor-3-(2-thenoyl)-2-oxindol-1-carboxamid - Google Patents

Lysinsalt af 6-chlor-5-fluor-3-(2-thenoyl)-2-oxindol-1-carboxamid

Info

Publication number
DK0680321T3
DK0680321T3 DK94906511T DK94906511T DK0680321T3 DK 0680321 T3 DK0680321 T3 DK 0680321T3 DK 94906511 T DK94906511 T DK 94906511T DK 94906511 T DK94906511 T DK 94906511T DK 0680321 T3 DK0680321 T3 DK 0680321T3
Authority
DK
Denmark
Prior art keywords
thenoyl
oxindole
carboxamide
fluoro
chloro
Prior art date
Application number
DK94906511T
Other languages
Danish (da)
English (en)
Inventor
Kelvin Cooper
Thomas C Crawford
Bruce H Littman
Christopher J Pazoles
Sally G Ruggeri
Keith D Wilner
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/007,217 external-priority patent/US5298522A/en
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0680321T3 publication Critical patent/DK0680321T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK94906511T 1993-01-22 1994-01-06 Lysinsalt af 6-chlor-5-fluor-3-(2-thenoyl)-2-oxindol-1-carboxamid DK0680321T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/007,217 US5298522A (en) 1993-01-22 1993-01-22 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio
US13827793A 1993-10-18 1993-10-18
PCT/US1994/000096 WO1994016694A1 (en) 1993-01-22 1994-01-06 Lysine salt of 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide

Publications (1)

Publication Number Publication Date
DK0680321T3 true DK0680321T3 (da) 1999-06-14

Family

ID=26676677

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94906511T DK0680321T3 (da) 1993-01-22 1994-01-06 Lysinsalt af 6-chlor-5-fluor-3-(2-thenoyl)-2-oxindol-1-carboxamid

Country Status (27)

Country Link
EP (1) EP0680321B1 (sh)
JP (1) JP2711939B2 (sh)
CN (1) CN1116822A (sh)
AP (1) AP468A (sh)
AT (1) ATE171373T1 (sh)
AU (1) AU671533B2 (sh)
BG (1) BG61966B1 (sh)
BR (1) BR9405661A (sh)
CA (1) CA2153050C (sh)
CZ (1) CZ182895A3 (sh)
DE (1) DE69413518T2 (sh)
DK (1) DK0680321T3 (sh)
DZ (1) DZ1748A1 (sh)
ES (1) ES2122236T3 (sh)
FI (1) FI940309A (sh)
HU (1) HUT69687A (sh)
IL (1) IL108326A0 (sh)
LV (1) LV10920B (sh)
MA (1) MA23095A1 (sh)
NO (1) NO952904L (sh)
NZ (1) NZ261449A (sh)
OA (1) OA10173A (sh)
PL (1) PL309957A1 (sh)
SK (1) SK91395A3 (sh)
UY (1) UY23723A1 (sh)
WO (1) WO1994016694A1 (sh)
YU (1) YU48719B (sh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7503496A (en) * 1995-12-19 1997-07-14 Pfizer Inc. Stable, long acting salts of indole derivatives for the treatment of joint diseases
EP0826685A1 (en) * 1996-08-21 1998-03-04 Pfizer Inc. Stable, long acting salts of carboxamides for the treatment of joint disease
DE10106852A1 (de) * 2001-02-14 2002-09-05 T Luger Entzündungshemmende Verbindungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4853409A (en) * 1988-04-13 1989-08-01 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
DE4111306C2 (de) * 1991-04-08 1994-06-01 Mack Chem Pharm Pharmazeutische Zubereitungen, die ein 2-Oxindol-l-carboxamid-derivat enthalten und zur Injektion bestimmt sind
DE4111305C2 (de) * 1991-04-08 1994-12-01 Mack Chem Pharm Pharmazeutische Zubereitung zur rektalen Applikation, die ein 2-Oxindol-l-carboxamid-derivat enthält
US5298522A (en) * 1993-01-22 1994-03-29 Pfizer Inc. 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio

Also Published As

Publication number Publication date
EP0680321A1 (en) 1995-11-08
IL108326A0 (en) 1994-04-12
DZ1748A1 (fr) 2002-02-17
ES2122236T3 (es) 1998-12-16
NO952904D0 (no) 1995-07-21
BG61966B1 (bg) 1998-11-30
HU9400176D0 (en) 1994-05-30
WO1994016694A1 (en) 1994-08-04
ATE171373T1 (de) 1998-10-15
MA23095A1 (fr) 1994-10-01
YU2394A (sh) 1996-10-18
EP0680321B1 (en) 1998-09-23
FI940309A0 (fi) 1994-01-21
BR9405661A (pt) 1995-11-21
YU48719B (sh) 1999-07-28
PL309957A1 (en) 1995-11-13
AU6019894A (en) 1994-08-15
AU671533B2 (en) 1996-08-29
CA2153050A1 (en) 1994-08-04
DE69413518D1 (en) 1998-10-29
UY23723A1 (es) 1994-06-28
SK91395A3 (en) 1996-12-04
LV10920B (en) 1996-04-20
AP468A (en) 1996-03-05
CA2153050C (en) 1998-12-29
CZ182895A3 (en) 1996-01-17
NZ261449A (en) 1996-08-27
HUT69687A (en) 1995-09-28
LV10920A (lv) 1995-12-20
CN1116822A (zh) 1996-02-14
OA10173A (en) 1996-12-18
FI940309A (fi) 1994-07-23
JPH08501109A (ja) 1996-02-06
NO952904L (no) 1995-07-21
BG99767A (bg) 1996-02-28
DE69413518T2 (de) 1999-02-11
JP2711939B2 (ja) 1998-02-10
AP9400609A0 (en) 1994-01-31

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