DK0679718T3 - Fremgangsmåde til fremstilling af alfa-interferon - Google Patents

Fremgangsmåde til fremstilling af alfa-interferon

Info

Publication number
DK0679718T3
DK0679718T3 DK95104596T DK95104596T DK0679718T3 DK 0679718 T3 DK0679718 T3 DK 0679718T3 DK 95104596 T DK95104596 T DK 95104596T DK 95104596 T DK95104596 T DK 95104596T DK 0679718 T3 DK0679718 T3 DK 0679718T3
Authority
DK
Denmark
Prior art keywords
alpha
production
alpha interferon
free
ifn
Prior art date
Application number
DK95104596T
Other languages
English (en)
Inventor
Erich Hochuli
Urs Ettlin
Alfred Schacher
Karl Weyer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0679718T3 publication Critical patent/DK0679718T3/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21B—ROLLING OF METAL
    • B21B13/00—Metal-rolling stands, i.e. an assembly composed of a stand frame, rolls, and accessories
    • B21B13/06—Metal-rolling stands, i.e. an assembly composed of a stand frame, rolls, and accessories with axes of rolls arranged vertically, e.g. edgers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK95104596T 1994-04-09 1995-03-29 Fremgangsmåde til fremstilling af alfa-interferon DK0679718T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94105532 1994-04-09

Publications (1)

Publication Number Publication Date
DK0679718T3 true DK0679718T3 (da) 2001-10-22

Family

ID=8215847

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95104596T DK0679718T3 (da) 1994-04-09 1995-03-29 Fremgangsmåde til fremstilling af alfa-interferon

Country Status (7)

Country Link
US (1) US6005075A (da)
EP (2) EP1104809A1 (da)
JP (1) JP2859162B2 (da)
AT (1) ATE205256T1 (da)
DE (1) DE69522492T2 (da)
DK (1) DK0679718T3 (da)
ES (1) ES2161793T3 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW491855B (en) * 1996-08-07 2002-06-21 Csl Ltd Purification of immunoglobulins
SI1129111T1 (sl) * 1998-11-12 2009-06-30 Schering Corp Postopki za pretvorbo interferonskih izooblik in proizvodi le-teh
WO2000039280A2 (en) * 1998-12-31 2000-07-06 Viragen, Inc. Leukocyte-derived interferon preparations
ES2266188T3 (es) 2000-03-27 2007-03-01 Genetics Institute, Llc Procedimientos de purificacion de proteinas altamente anionicas.
DK1714982T3 (da) * 2001-06-05 2009-05-04 Genetics Inst Llc Fremgangsmåde til rensning af stærkt anioniske proteiner
ITBO20010426A1 (it) * 2001-07-06 2003-01-06 Alfa Wassermann Spa Processo per la purificazione di proteine farmacologicamente attive mediante cromatografia in scambio cationico
ITMI20012345A1 (it) * 2001-11-08 2003-05-08 Internat Ct For Genetic En Gin Procedimento per la produzione di interferone alfa di grado terapeutico
AU2002304965A1 (en) 2002-05-24 2003-12-12 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
WO2005123113A2 (en) * 2004-06-14 2005-12-29 Intermune, Inc. Interferon compositions and methods of use thereof
CN107033233A (zh) 2008-01-18 2017-08-11 弗·哈夫曼-拉罗切有限公司 非糖基化蛋白质的纯化
AU2009330278B2 (en) 2008-12-23 2013-01-31 Merck Sharp & Dohme Corp. Purification of recombinantly produced interferon
DE102010046817A1 (de) * 2010-09-28 2012-03-29 Sartorius Stedim Biotech Gmbh Verfahren zur Abtrennung von Viren aus einem Kontaminanten enthaltenden flüssigen Medium
CN114671944A (zh) * 2022-04-29 2022-06-28 江苏尤里卡生物科技有限公司 一种人绒毛膜***纯化方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH651308A5 (de) * 1980-07-01 1985-09-13 Hoffmann La Roche Interferone und deren herstellung.
US4485038A (en) * 1982-10-19 1984-11-27 Health Research (Roswell Park Division) Method for the production and purification of human leukocyte interferon
US4620948A (en) * 1982-12-22 1986-11-04 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
CA1231306A (en) * 1983-03-03 1988-01-12 Erich Hochuli Purification of interferon
AU598455B2 (en) * 1984-12-27 1990-06-28 Suntory Limited Method for purifying an interferon
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
JPS6411640A (en) * 1987-07-02 1989-01-17 Engelhard Nippon Precious metal adsorbent
WO1992010207A1 (en) * 1990-12-14 1992-06-25 Schering Corporation Oral administration of alpha interferon to treat lung malignancies
AU648214B2 (en) * 1991-12-31 1994-04-14 Lucky Limited Recombinant gene coding for human alpha interferon and expression vector thereof, etc.

Also Published As

Publication number Publication date
EP0679718B1 (en) 2001-09-05
US6005075A (en) 1999-12-21
JPH07322887A (ja) 1995-12-12
ATE205256T1 (de) 2001-09-15
EP0679718A3 (en) 1996-08-21
EP0679718A2 (en) 1995-11-02
JP2859162B2 (ja) 1999-02-17
ES2161793T3 (es) 2001-12-16
EP1104809A1 (en) 2001-06-06
DE69522492T2 (de) 2002-05-23
DE69522492D1 (de) 2001-10-11

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