DK0679082T3 - C10-Taxanderivater og farmaceutiske præparater - Google Patents

C10-Taxanderivater og farmaceutiske præparater

Info

Publication number: DK0679082T3
Authority: DK; Denmark
Prior art keywords: pharmaceuticals; taxane derivatives; novel; taxane; antileukemia
Prior art date: 1993-01-15

Application number

DK94909453T

Other languages

Danish (da)

English (en)

Inventor

Robert A Holton

Ki-Byung Chai

Original Assignee

Univ Florida State

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-15

Filing date

1994-01-14

Publication date

2003-02-17

1993-01-15 Priority claimed from US08/005,229 external-priority patent/US5338872A/en

1994-01-14 Application filed by Univ Florida State filed Critical Univ Florida State

2003-02-17 Application granted granted Critical

2003-02-17 Publication of DK0679082T3 publication Critical patent/DK0679082T3/da

Links

DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
230000000719 anti-leukaemic effect Effects 0.000 abstract 1
239000000063 antileukemic agent Substances 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)

DK94909453T 1993-01-15 1994-01-14 C10-Taxanderivater og farmaceutiske præparater DK0679082T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US08/005,229 US5338872A (en)	1993-01-15	1993-01-15	Process for the preparation of 10-desacetoxybaccatin III and 10-desacetoxytaxol and derivatives thereof
US3485293A	1993-03-22	1993-03-22
US9454593A	1993-07-20	1993-07-20
PCT/US1994/000479 WO1994015599A1 (en)	1993-01-15	1994-01-14	C10 taxane derivatives and pharmaceutical compositions

Publications (1)

Publication Number	Publication Date
DK0679082T3 true DK0679082T3 (da)	2003-02-17

Family

ID=27357839

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK02005075T DK1211250T3 (da)	1993-01-15	1994-01-14	C10-Taxanderivater samt farmaceutiske præparater
DK94909453T DK0679082T3 (da)	1993-01-15	1994-01-14	C10-Taxanderivater og farmaceutiske præparater

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK02005075T DK1211250T3 (da)	1993-01-15	1994-01-14	C10-Taxanderivater samt farmaceutiske præparater

Country Status (12)

Country	Link
EP (2)	EP0679082B1 (zh)
JP (1)	JP3917173B2 (zh)
CN (2)	CN1244569C (zh)
AT (2)	ATE225656T1 (zh)
AU (1)	AU682852B2 (zh)
CA (1)	CA2153805C (zh)
DE (2)	DE69431514T2 (zh)
DK (2)	DK1211250T3 (zh)
ES (2)	ES2184761T3 (zh)
IL (1)	IL108316A (zh)
PT (2)	PT679082E (zh)
WO (1)	WO1994015599A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5710287A (en)	1991-09-23	1998-01-20	Florida State University	Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US5440056A (en) *	1992-04-17	1995-08-08	Abbott Laboratories	9-deoxotaxane compounds
CA2153903C (en) *	1993-01-15	2004-11-02	Robert A. Holton	Process for the preparation of 10-desacetoxybaccatin iii
IL108443A0 (en) *	1993-01-29	1994-04-12	Univ Florida State	C7 taxane derivatives and pharmaceutical compositions containing them
US5677470A (en) *	1994-06-28	1997-10-14	Tanabe Seiyaku Co., Ltd.	Baccatin derivatives and processes for preparing the same
CA2162759A1 (en) *	1994-11-17	1996-05-18	Kenji Tsujihara	Baccatin derivatives and processes for preparing the same
HU226325B1 (en) *	1995-09-12	2008-08-28	Cephalon Ltd	Hydrolysis-promoting hydrophobic taxane derivatives, medicaments comprising them and the use of medicaments
US5773464A (en) *	1996-09-30	1998-06-30	Bristol-Myers Squibb Company	C-10 epoxy taxanes
CA2410632A1 (en)	2000-06-22	2001-12-27	David S. Garvey	Nitrosated and nitrosylated taxanes, compositions and methods of use
US8785669B2 (en) *	2010-06-30	2014-07-22	Gfv, Llc	Taxane compounds, compositions and methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4960790A (en) *	1989-03-09	1990-10-02	University Of Kansas	Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
US5175315A (en) *	1989-05-31	1992-12-29	Florida State University	Method for preparation of taxol using β-lactam
US5250683A (en) *	1991-09-23	1993-10-05	Florida State University	Certain substituted taxanes and pharmaceutical compositions containing them
US5243045A (en) *	1991-09-23	1993-09-07	Florida State University	Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5200534A (en) *	1992-03-13	1993-04-06	University Of Florida	Process for the preparation of taxol and 10-deacetyltaxol
US5248796A (en) *	1992-06-18	1993-09-28	Bristol-Myers Squibb Company	Taxol derivatives
CA2109861C (en) *	1992-12-04	1999-03-16	Shu-Hui Chen	6,7-modified paclitaxels
FR2707293A1 (fr) *	1993-07-08	1995-01-13	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur préparation et les compositions pharmaceutiques qui les contiennent.

1994
- 1994-01-11 IL IL108316A patent/IL108316A/en not_active IP Right Cessation
- 1994-01-14 DK DK02005075T patent/DK1211250T3/da active
- 1994-01-14 EP EP94909453A patent/EP0679082B1/en not_active Expired - Lifetime
- 1994-01-14 CA CA002153805A patent/CA2153805C/en not_active Expired - Fee Related
- 1994-01-14 ES ES94909453T patent/ES2184761T3/es not_active Expired - Lifetime
- 1994-01-14 JP JP51632894A patent/JP3917173B2/ja not_active Expired - Fee Related
- 1994-01-14 PT PT94909453T patent/PT679082E/pt unknown
- 1994-01-14 DE DE69431514T patent/DE69431514T2/de not_active Expired - Fee Related
- 1994-01-14 WO PCT/US1994/000479 patent/WO1994015599A1/en active IP Right Grant
- 1994-01-14 AU AU62295/94A patent/AU682852B2/en not_active Ceased
- 1994-01-14 ES ES02005075T patent/ES2225671T3/es not_active Expired - Lifetime
- 1994-01-14 DE DE69433856T patent/DE69433856T2/de not_active Expired - Fee Related
- 1994-01-14 PT PT02005075T patent/PT1211250E/pt unknown
- 1994-01-14 AT AT94909453T patent/ATE225656T1/de not_active IP Right Cessation
- 1994-01-14 DK DK94909453T patent/DK0679082T3/da active
- 1994-01-14 EP EP02005075A patent/EP1211250B1/en not_active Expired - Lifetime
- 1994-01-14 AT AT02005075T patent/ATE269315T1/de not_active IP Right Cessation
- 1994-01-15 CN CNB031579078A patent/CN1244569C/zh not_active Expired - Fee Related
- 1994-01-15 CN CN94100725A patent/CN1125060C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN1125060C (zh)	2003-10-22
WO1994015599A1 (en)	1994-07-21
DE69433856D1 (de)	2004-07-22
DK1211250T3 (da)	2004-10-25
ATE269315T1 (de)	2004-07-15
DE69433856T2 (de)	2004-11-04
IL108316A (en)	2006-10-31
DE69431514T2 (de)	2003-02-13
JP3917173B2 (ja)	2007-05-23
PT679082E (pt)	2003-02-28
CN1495177A (zh)	2004-05-12
EP0679082A4 (en)	1995-12-20
DE69431514D1 (de)	2002-11-14
CN1244569C (zh)	2006-03-08
PT1211250E (pt)	2004-10-29
ES2184761T3 (es)	2003-04-16
JPH08505627A (ja)	1996-06-18
IL108316A0 (en)	1994-04-12
EP0679082B1 (en)	2002-10-09
AU682852B2 (en)	1997-10-23
CN1097746A (zh)	1995-01-25
ATE225656T1 (de)	2002-10-15
EP1211250B1 (en)	2004-06-16
CA2153805C (en)	2006-03-28
EP0679082A1 (en)	1995-11-02
AU6229594A (en)	1994-08-15
ES2225671T3 (es)	2005-03-16
EP1211250A1 (en)	2002-06-05
CA2153805A1 (en)	1994-07-21

Publication	Publication Date	Title
DK1627880T3 (da)	2008-12-08	Boronester og -syreforbindelser samt syntese og anvendelser
DE69319976D1 (de)	1998-09-03	7-Substituierte-9-substituierte Glycylamido-6-Demethyl-6-Deoxytetracycline
DK0501797T3 (da)	1996-06-24	Pyranylcyanoguanidinderivater
MX9204598A (es)	1993-02-01	Conjunto exhibidor portatil.
DK0425650T3 (da)	1995-12-27	Antiinflammatoriske 4-aminophenolderivater
DE69007062D1 (de)	1994-04-07	Richtungsabhängige linienförmige Lichtquelle.
DK0679082T3 (da)	2003-02-17	C10-Taxanderivater og farmaceutiske præparater
DE69314942D1 (de)	1997-12-04	N-acylglutamin-derivate
ATE131164T1 (de)	1995-12-15	2-(rs)-substituierte-2,3-dihydro-5-oxy-4,6,7- trimethyl-benzofurane, verwendbar als antioxydante arzneimittel mit mukoregulierender und anti-ischemischer wirkung.
ATE182594T1 (de)	1999-08-15	Thiazolotriazol- und thiazolodiazolderivate mit fungizider aktivität
DE69329038D1 (de)	2000-08-17	Psicofuranose und psicopyranose derivate
DE59203799D1 (de)	1995-11-02	Acylierte Aminophenol-Derivate.
DE69523433D1 (de)	2001-11-29	Die verbindung ge3
DE69328495D1 (de)	2000-05-31	2,3-Dihydrobenzofuran Derivate
DE59102075D1 (de)	1994-08-04	Ladenband.
ATE136884T1 (de)	1996-05-15	Neue 2-mercaptomethylen-tetrahydronaphthalin- und -indan-2-carboxamide als enkephalinaseinhibitoren
FR2703260B1 (fr)	1995-06-30	Labyrinthe coulissant.
DK1108716T3 (da)	2005-01-31	C7-texanderivater og farmaceutiske præparater, der indeholder disse
FR2673441B1 (fr)	1993-05-07	Portail demontable.
IT232210Y1 (it)	1999-12-17	Portatutto regolabile-orizzontale.
DE69202436D1 (de)	1995-06-14	Ramaneffekt-Laser.
ITAN910008A1 (it)	1992-03-20	Raffreddamento di ruota con due sbilanciamenti.