DK0666918T3 - Fremstilling af gamma-linolensyre ved hjælp af en delta-6-desaturase - Google Patents

Fremstilling af gamma-linolensyre ved hjælp af en delta-6-desaturase

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Publication number
DK0666918T3
DK0666918T3 DK92922205T DK92922205T DK0666918T3 DK 0666918 T3 DK0666918 T3 DK 0666918T3 DK 92922205 T DK92922205 T DK 92922205T DK 92922205 T DK92922205 T DK 92922205T DK 0666918 T3 DK0666918 T3 DK 0666918T3
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DK
Denmark
Prior art keywords
delta
desaturase
gamma
linolenic acid
preparation
Prior art date
Application number
DK92922205T
Other languages
English (en)
Inventor
Terry Thomas
Avutu S Reddy
Michael Nuccio
Georges Freyssinet
Original Assignee
Bayer Cropscience Sa
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Publication date
Application filed by Bayer Cropscience Sa filed Critical Bayer Cropscience Sa
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Publication of DK0666918T3 publication Critical patent/DK0666918T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19003Linoleoyl-CoA desaturase (1.14.19.3)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Saccharide Compounds (AREA)
DK92922205T 1991-10-10 1992-10-13 Fremstilling af gamma-linolensyre ved hjælp af en delta-6-desaturase DK0666918T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77447591A 1991-10-10 1991-10-10
US81791992A 1992-01-08 1992-01-08
PCT/US1992/008746 WO1993006712A1 (en) 1991-10-10 1992-10-13 Production of gamma linolenic acid by a δ6-desaturase

Publications (1)

Publication Number Publication Date
DK0666918T3 true DK0666918T3 (da) 2005-03-14

Family

ID=27118889

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92922205T DK0666918T3 (da) 1991-10-10 1992-10-13 Fremstilling af gamma-linolensyre ved hjælp af en delta-6-desaturase

Country Status (23)

Country Link
US (3) US5552306A (da)
EP (1) EP0666918B1 (da)
JP (1) JP3537434B2 (da)
KR (1) KR100316068B1 (da)
CN (2) CN1053469C (da)
AT (1) ATE284961T1 (da)
AU (1) AU667848B2 (da)
BG (1) BG61791B1 (da)
BR (1) BR9206613A (da)
CA (1) CA2120629C (da)
CZ (1) CZ285471B6 (da)
DE (1) DE69233459T2 (da)
DK (1) DK0666918T3 (da)
ES (1) ES2231767T3 (da)
HU (1) HU217328B (da)
IL (1) IL103407A (da)
MX (1) MX9205820A (da)
NZ (1) NZ244685A (da)
PH (1) PH31293A (da)
RO (1) RO113256B1 (da)
RU (1) RU2152996C2 (da)
UA (1) UA43314C2 (da)
WO (1) WO1993006712A1 (da)

Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070130654A1 (en) * 1991-10-10 2007-06-07 Thomas Terry L Production of gamma linolenic acid by a delta6-desaturase
US5614393A (en) * 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
US6372965B1 (en) 1992-11-17 2002-04-16 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and hydroxylases from plants
US6872872B1 (en) 1992-11-17 2005-03-29 E. I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
JPH08506490A (ja) * 1993-02-05 1996-07-16 モンサント・カンパニー 植物中の改変リノレン酸及びリノール酸含量
US5639645A (en) * 1993-09-22 1997-06-17 Mitsubishi Corporation Recombinant Δ9 desaturase and a gene encoding the same
US6310194B1 (en) * 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
US5965793A (en) 1995-09-20 1999-10-12 Monsanto Company, Inc. Strong early seed-specific gene regulatory region
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
US5959175A (en) * 1997-04-09 1999-09-28 Thomas; Terry L. Sunflower albumin 5' regulatory region for the modification of plant seed lipid composition
US6051754A (en) * 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6075183A (en) * 1997-04-11 2000-06-13 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US7745694B1 (en) 1997-04-11 2010-06-29 Monsanto Technology Llc Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US5968809A (en) * 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
HUP0001517A3 (en) * 1997-04-11 2002-04-29 Calgene Llc Davis Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US6432684B1 (en) 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
US6428990B1 (en) 1997-04-11 2002-08-06 Abbott Laboratories Human desaturase gene and uses thereof
MX224646B (es) * 1997-04-15 2004-12-03 Commw Scient Ind Res Org Genes de acido graso epoxigenasa de vegetales y usos de los mismos
US6080911A (en) * 1997-04-15 2000-06-27 Ohio University Mice models of growth hormone insensitivity
US6100450A (en) * 1997-10-22 2000-08-08 Rhone-Poulenc Agrochimie Seed specific promoters based on arabidopsis genes
JP2002516093A (ja) * 1998-05-29 2002-06-04 オハイオ ユニバーシティー 脂肪酸、その誘導体および下流産物を合成するための組成物および方法
DK1086236T3 (da) 1998-06-12 2007-12-03 Calgene Llc Polyumættede fedtsyrer i planter
US20030163845A1 (en) * 1998-09-02 2003-08-28 Pradip Mukerji Elongase genes and uses thereof
US6403349B1 (en) 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
US6677145B2 (en) 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US6913916B1 (en) 1998-09-02 2005-07-05 Abbott Laboratories Elongase genes and uses thereof
DK1181373T3 (da) 1999-06-07 2006-11-27 Basf Plant Science Gmbh Delta-6-acetylenase og delta-6-desaturase ud fra Ceratodon purpureus
DE10030976A1 (de) 2000-06-30 2002-01-10 Basf Ag DELTA6-Desaturasegene exprimierende Pflanzen und PUFAS enthaltende Öle aus diesen Pflanzen und ein Verfahren zur Herstellung ungesättigter Fettsäuren
US7070970B2 (en) 1999-08-23 2006-07-04 Abbott Laboratories Elongase genes and uses thereof
GB9929897D0 (en) * 1999-12-18 2000-02-09 Slabas Antoni R Improvements in or relating to conjugated fatty acids and related compounds
FR2803592A1 (fr) 2000-01-06 2001-07-13 Aventis Cropscience Sa Nouveaux derives de l'acide 3-hydroxypicolinique, leur procede de preparation et compositions fongicides les contenant.
FR2810994B1 (fr) * 2000-06-30 2004-03-12 Biogemma Fr Acides nucleiques codant pour une phosphatase vegetale de type mipp a activite phytasique et applications
EP1197550A3 (en) * 2000-08-25 2002-11-20 Pfizer Products Inc. Methods and compositions for diagnosing and treating disorders involving angiogenesis
ATE510908T1 (de) 2000-09-28 2011-06-15 Bioriginal Food & Science Corp Fad5-2, mitglied der desaturase-familie und verwendungen davon
FR2815969B1 (fr) 2000-10-30 2004-12-10 Aventis Cropscience Sa Plantes tolerantes aux herbicides par contournement de voie metabolique
DE10102337A1 (de) 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
WO2002081668A2 (en) * 2001-01-25 2002-10-17 Abbott Laboratories Desaturase genes and uses thereof
US6635451B2 (en) 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
US7045683B2 (en) * 2001-05-04 2006-05-16 Abbott Laboratories Δ4-desaturase genes and uses thereof
EP2275101A1 (en) * 2001-05-14 2011-01-19 Martek Biosciences Corporation Polar lipid-rich fraction containing stearidonic acid and gamma linolenic acid from plant seeds and microbes, and its uses
EP1392623A4 (en) * 2001-05-14 2005-05-04 Martek Biosciences Corp PREPARATION AND USE OF A POLAR LIPID RICH FRACTION CONTAINING HIGHLY UNSATURATED OMEGA-3 AND / OR OMEGA-6 FATTY ACIDS FROM MICROBES, SEEDS OF GENETICALLY MODIFIED PLANTS AND MARINE ORGANISMS
BR0306883A (pt) 2002-01-30 2004-12-07 Basf Plant Science Gmbh ácido nucléico isolado, sequências de ácido nucléico isolado e de aminoácido, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou uma fração destes, composição de óleo, lipìdeo ou de ácido graxo, e, uso da mesma
US7211656B2 (en) * 2002-01-30 2007-05-01 Abbott Laboratories Desaturase genes, enzymes encoded thereby, and uses thereof
GB2385852A (en) 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
WO2005024017A1 (en) * 2002-03-15 2005-03-17 Monsanto Technology Llc Nucleic acid molecules associated with oil in plants
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
EP2216405A1 (en) 2002-05-03 2010-08-11 Monsanto Technology LLC Speed specific USP promoters for expressing genes in plants
FR2848064B1 (fr) * 2002-12-06 2006-01-13 Bayer Cropscience Sa Plantes legumineuses transplastomiques fertiles
FR2848570B1 (fr) 2002-12-12 2005-04-01 Bayer Cropscience Sa Cassette d'expression codant pour une 5-enol pyruvylshikimate-3-phosphate synthase (epsps) et plantes tolerantes aux herbicides la contenant
US7078234B2 (en) 2002-12-18 2006-07-18 Monsanto Technology Llc Maize embryo-specific promoter compositions and methods for use thereof
BR0317304A (pt) 2002-12-19 2005-11-08 Univ Bristol Processo para a produção de compostos, sequência de ácido nucleico isolada, sequência de aminoácidos, construção gênica, vetor, e, organismo
ATE517984T1 (de) 2003-02-27 2011-08-15 Basf Plant Science Gmbh Verfahren zur herstellung mehrfach ungesättigter fettsäuren
EP2116606B1 (en) 2003-03-28 2012-12-19 Monsanto Technology, LLC Novel plant promoters for use in early seed development
WO2004087902A2 (de) 2003-03-31 2004-10-14 University Of Bristol Neue pflanzliche acyltransferasen spezifisch für langkettige mehrfach ungesättigte fettsäuren
MXPA05010571A (es) 2003-04-08 2005-11-23 Basf Plant Science Gmbh Delta-4-desaturasas a partir de euglena gracilis, que expresan plantas y aceites que comprenden pufa
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
EP1654344B1 (de) 2003-08-01 2018-10-17 BASF Plant Science GmbH Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen
DE602004021001D1 (de) 2003-08-21 2009-06-18 Monsanto Technology Llc Fettsäuredesaturasen aus primula
CA2450000A1 (en) * 2003-12-18 2005-06-18 Alberta Research Council Inc. Method of creating plants with reduced level of saturated fatty acid in seed oil
MXPA06009572A (es) 2004-02-27 2007-05-23 Basf Plant Science Gmbh Metodo para la produccion de acidos grasos poliinsaturados en plantas transgenicas.
US7777098B2 (en) 2004-02-27 2010-08-17 Basf Plant Science Gmbh Method for producing unsaturated ω-3-fatty acids in transgenic organisms
US20050220901A1 (en) * 2004-03-22 2005-10-06 Huttenbauer Samuel Jr Methods of pharmaceutical separation from plants
CA2562548C (en) 2004-04-16 2019-08-20 Monsanto Technology Llc Expression of fatty acid desaturases in corn
CA2884237C (en) 2004-04-22 2020-09-08 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
ES2529572T3 (es) 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
US7138391B2 (en) * 2004-08-09 2006-11-21 Silverbrook Research Pty Ltd Hydrophilizable and hydrophilic cyanine dyes
US7456270B2 (en) * 2004-09-01 2008-11-25 Abbott Laboratories Δ6-desaturase genes and uses thereof
CN101128591B (zh) 2005-02-26 2013-02-13 巴斯福植物科学有限公司 用于植物中种子偏好性表达的表达盒
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
AU2006257101B2 (en) 2005-04-19 2011-04-28 Basf Plant Science Gmbh Starchy-endosperm and/or germinating embryo-specific expression in mono-cotyledonous plants
AU2006237346B2 (en) 2005-04-20 2011-04-07 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
WO2006120197A2 (en) 2005-05-10 2006-11-16 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
CA2609367C (en) 2005-05-23 2014-08-19 Arcadia Biosciences, Inc. Safflower with elevated gamma-linolenic acid
DE102005038036A1 (de) 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
GB2431158A (en) 2005-10-13 2007-04-18 Rothamsted Res Ltd Process for the production of arachidonic and/or eicosapentaenoic acid
DE102005052551A1 (de) 2005-11-02 2007-05-16 Rothamsted Res Harpenden Verfahren zur Herstellung von y-Linolensäure und/oder Stearidonsäure in transgenen Brassicaceae und Linaceae
EP1806398A1 (en) * 2006-01-04 2007-07-11 Monsanto S.A.S. Fad-2 mutants and high oleic plants
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
US8629195B2 (en) 2006-04-08 2014-01-14 Bayer Materialscience Ag Production of polyurethane foams
BRPI0714390B1 (pt) 2006-07-19 2018-05-15 Monsanto Technology Llc Polinucleotídeo, construção de dna, célula hospedeira fúngica ou bacteriana, processo para produção de alimento ou de produto alimentício e composição para alimento ou produto alimentício
WO2008022963A2 (en) 2006-08-24 2008-02-28 Basf Plant Science Gmbh Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
WO2008025068A1 (en) 2006-08-29 2008-03-06 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
WO2008040787A2 (de) 2006-10-06 2008-04-10 Basf Plant Science Gmbh Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen organismen
WO2008099013A1 (en) 2007-02-16 2008-08-21 Basf Plant Science Gmbh Nucleic acid sequences for regulation of embryo-specific expression in monocotyledonous plants
SG10201509864QA (en) 2007-06-01 2015-12-30 Solazyme Inc Production of oil in microorganisms
US8318914B2 (en) 2007-07-31 2012-11-27 Bioriginal Food & Science Corp. Elongases and methods for producing polyunsaturated fatty acids in transgenic organisms
US20130323801A1 (en) * 2007-11-01 2013-12-05 Wake Forest University School Of Medicine Compositions, Methods, and Kits for Polyunsaturated Fatty Acids from Microalgae
CA2708087A1 (en) 2007-12-14 2009-06-25 Bioriginal Food & Science Corp. Promoters from brassica napus for seed specific gene expression
CN102066564B (zh) 2008-04-30 2015-02-11 罗特哈姆斯泰德研究有限公司 去饱和酶和在转基因生物中产生多不饱和脂肪酸的方法
US8853383B2 (en) 2008-07-01 2014-10-07 Basf Plant Science Gmbh Promoters from Brassica napus for seed specific gene expression
CA2734810C (en) 2008-08-26 2018-06-19 Basf Plant Science Gmbh Nucleic acids encoding desaturases and modified plant oil
CA2743880C (en) 2008-11-18 2020-08-18 James Robertson Petrie Recombinant cells comprising exogenous a5 elongase and methods for producing docosapentaenoic acid
EP2370554B1 (en) 2008-11-28 2019-05-15 Corbion Biotech, Inc. Manufacturing of tailored oils in recombinant heterotrophic microorganisms
ES2653727T3 (es) 2008-12-12 2018-02-08 Basf Plant Science Gmbh Desaturasas y proceso para la producción de ácidos grasos poliinsaturados en organismos transgénicos
AR074941A1 (es) 2009-01-07 2011-02-23 Bayer Cropscience Sa Plantas transplastomicas exentas de marcador de seleccion
WO2010118477A1 (en) 2009-04-17 2010-10-21 Molecular Plant Breeding Nominees Ltd Plant promoter operable in endosperm and uses thereof
BRPI1012750B1 (pt) 2009-04-22 2019-04-16 Basf Plant Science Company Gmbh Polinucleotídeo, vetor, célula hospedeira, método para expressar um ácido nucléico de interesse, e, uso do polinucleotídeo.
CA2760326A1 (en) 2009-05-13 2010-11-18 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
CA2766858A1 (en) 2009-07-10 2011-01-13 Basf Plant Science Company Gmbh Expression cassettes for endosperm-specific expression in plants
US8188335B2 (en) 2009-07-17 2012-05-29 Abbott Laboratories Δ9-elongase for production of polyunsaturated fatty acid-enriched oils
BR112012013156A2 (pt) 2009-12-03 2017-06-13 Basf Plant Science Co Gmbh cassete de expressão, vetor, célula horpedeira, tecido de planta transgênica e método para a produção de um tecido de planta transgênica
EP2531601B1 (en) 2010-02-02 2016-11-16 Bayer Intellectual Property GmbH Soybean transformation using HPPD inhibitors as selection agents
AU2011257982B2 (en) 2010-05-28 2017-05-25 Corbion Biotech, Inc. Tailored oils produced from recombinant heterotrophic microorganisms
EP2585603B1 (en) 2010-06-25 2017-12-20 BASF Plant Science Company GmbH Acyltransferases and uses therof in fatty acid production
SG10201509035WA (en) 2010-11-03 2015-12-30 Solazyme Inc Microbial Oils With Lowered Pour Points, Dielectric Fluids Produced Therefrom, And Related Methods
KR101964965B1 (ko) 2011-02-02 2019-04-03 테라비아 홀딩스 인코포레이티드 재조합 유지성 미생물로부터 생산된 맞춤 오일
AU2013246661B2 (en) 2012-04-12 2018-12-20 Rothamsted Research Ltd Production of omega-3 long chain polyunsaturated fatty acids
BR112014025719A8 (pt) 2012-04-18 2017-10-03 Solazyme Inc Óleos customizados
US9719114B2 (en) 2012-04-18 2017-08-01 Terravia Holdings, Inc. Tailored oils
HUE033766T2 (en) 2012-06-15 2018-01-29 Commw Scient Ind Res Org Preparation of long chain polyunsaturated fatty acids in plant cells
GB201217524D0 (en) 2012-10-01 2012-11-14 Rothamsted Res Ltd Recombinant organisms
EP2993993A2 (en) * 2013-04-26 2016-03-16 Solazyme, Inc. Low polyunsaturated fatty acid oils and uses thereof
MX369685B (es) 2013-10-04 2019-11-19 Terravia Holdings Inc Aceites adaptables.
PE20170253A1 (es) 2013-12-18 2017-04-14 Nuseed Pty Ltd Lipido que comprende acidos grasos poliinsaturados de cadena larga
KR102527795B1 (ko) 2014-06-27 2023-05-02 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 도코사펜타에노산을 포함하는 지질
EP3620517A3 (en) 2014-07-10 2020-07-29 Corbion Biotech, Inc. Ketoacyl acp synthase genes and uses thereof
KR102054762B1 (ko) 2018-03-06 2020-01-22 대한민국(관리청: 특허청장, 승계청: 농촌진흥청장) 갈고리 흰오징어 유래의 지방산 사슬연장효소 유전자 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4736866B1 (en) * 1984-06-22 1988-04-12 Transgenic non-human mammals
NZ221259A (en) * 1986-07-31 1990-05-28 Calgene Inc Seed specific transcriptional regulation
CA1333397C (en) * 1987-11-04 1994-12-06 Jean Bernard Ducep Fluorinated arachidonic acid derivatives
BR9007159A (pt) * 1989-02-24 1991-12-10 Monsanto Co Genes sinteticos de plantas e processo para a preparacao dos mesmos
ATE241007T1 (de) * 1990-03-16 2003-06-15 Calgene Llc Dnas, die für pflanzliche desaturasen kodieren und deren anwendungen

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RU2152996C2 (ru) 2000-07-20
UA43314C2 (uk) 2001-12-17
US5663068A (en) 1997-09-02
EP0666918A4 (en) 1995-03-17
BG98695A (bg) 1995-05-31
US5689050A (en) 1997-11-18
CN1174236A (zh) 1998-02-25
IL103407A (en) 1999-09-22
HUT69781A (en) 1995-09-28
AU667848B2 (en) 1996-04-18
AU2881292A (en) 1993-05-03
KR100316068B1 (ko) 2002-11-13
IL103407A0 (en) 1993-03-15
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CN1121499C (zh) 2003-09-17
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HU9401007D0 (en) 1994-08-29
DE69233459D1 (de) 2005-01-20
MX9205820A (es) 1993-04-01
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US5552306A (en) 1996-09-03
CA2120629A1 (en) 1993-04-15
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CN1072722A (zh) 1993-06-02
CZ285471B6 (cs) 1999-08-11
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