DK0649849T3 - Fremgangsmåde til fremstilling af cephalosporiner - Google Patents

Fremgangsmåde til fremstilling af cephalosporiner

Info

Publication number
DK0649849T3
DK0649849T3 DK94116660T DK94116660T DK0649849T3 DK 0649849 T3 DK0649849 T3 DK 0649849T3 DK 94116660 T DK94116660 T DK 94116660T DK 94116660 T DK94116660 T DK 94116660T DK 0649849 T3 DK0649849 T3 DK 0649849T3
Authority
DK
Denmark
Prior art keywords
cephalosporins
preparation
cephalosporin
hydroxymethyl
dioxycarbenium
Prior art date
Application number
DK94116660T
Other languages
Danish (da)
English (en)
Inventor
Johann Danklmaier
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Application granted granted Critical
Publication of DK0649849T3 publication Critical patent/DK0649849T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DK94116660T 1993-10-22 1994-10-21 Fremgangsmåde til fremstilling af cephalosporiner DK0649849T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0214393A AT401177B (de) 1993-10-22 1993-10-22 Verfahren zur herstellung von 7-amino-3-cephem-4-carbonsäure-derivaten

Publications (1)

Publication Number Publication Date
DK0649849T3 true DK0649849T3 (da) 2000-12-18

Family

ID=3528693

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94116660T DK0649849T3 (da) 1993-10-22 1994-10-21 Fremgangsmåde til fremstilling af cephalosporiner

Country Status (13)

Country Link
US (1) US5597914A (de)
EP (2) EP0649849B1 (de)
JP (1) JP2875170B2 (de)
KR (1) KR100331251B1 (de)
CN (2) CN1050842C (de)
AT (2) AT401177B (de)
DE (1) DE69426006T2 (de)
DK (1) DK0649849T3 (de)
ES (1) ES2151525T3 (de)
GR (1) GR3034813T3 (de)
PT (1) PT649849E (de)
SG (1) SG64928A1 (de)
SI (1) SI0649849T1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030135041A1 (en) * 2002-01-04 2003-07-17 Orchid Chemicals & Pharmaceuticals Limited, India Synthesis of ceftiofur intermediate
AR090964A1 (es) 2012-05-09 2014-12-17 Novartis Ag Proceso para la elaboracion de undecapeptidos ciclicos
EP3426663B1 (de) 2016-03-07 2020-01-29 Dhanuka Laboratories Ltd. Verfahren zur alkylierung der hydroxymethylgruppe an position -3 von cephalosporinen

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1241656A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
GB1241657A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
JPS57192392A (en) * 1981-05-19 1982-11-26 Sankyo Co Ltd Production of 3-alkoxymethylcephalosporin
JPS59163387A (ja) * 1983-03-07 1984-09-14 Sankyo Co Ltd 3−アルコキシメチルセフアロスポリンの製造方法
AT384222B (de) * 1985-06-03 1987-10-12 Biochemie Gmbh Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren
DE3789412T2 (de) * 1986-10-02 1994-06-30 Asahi Chemical Ind Verfahren zur Herstellung von 3-Alkoxymethylcephalosporinen.
JPS63115887A (ja) * 1986-11-04 1988-05-20 Asahi Chem Ind Co Ltd 7−アミノ−3−アルコキシメチルセフアロスポリン類の製造方法
JP2612493B2 (ja) * 1988-05-24 1997-05-21 旭化成工業株式会社 3―置換メチル―3―セフェム―4―カルボン酸類の製造方法
DE4004370A1 (de) * 1990-02-13 1991-08-14 Hoechst Ag Verfahren zur herstellung von 7-amino-3-methoxymethyl-ceph-3-em-4-carbonsaeure
DE69110107T2 (de) * 1990-11-07 1996-02-01 Sankyo Co Verfahren zur Herstellung von 3-Alkoxymethyl Cephalosporinderivate.
US5221739A (en) * 1992-01-09 1993-06-22 Eli Lilly And Company Acetylation of 3-hydroxymethyl cephalosporins

Also Published As

Publication number Publication date
JPH07149767A (ja) 1995-06-13
AT401177B (de) 1996-07-25
ES2151525T3 (es) 2001-01-01
KR950011449A (ko) 1995-05-15
DE69426006T2 (de) 2001-05-17
ATE196632T1 (de) 2000-10-15
DE69426006D1 (de) 2000-11-02
CN1050842C (zh) 2000-03-29
CN1106409A (zh) 1995-08-09
GR3034813T3 (en) 2001-02-28
PT649849E (pt) 2001-02-28
EP0649849A1 (de) 1995-04-26
EP0649849B1 (de) 2000-09-27
ATA214393A (de) 1995-11-15
KR100331251B1 (ko) 2002-11-16
EP0908461A1 (de) 1999-04-14
JP2875170B2 (ja) 1999-03-24
SG64928A1 (en) 1999-05-25
SI0649849T1 (en) 2001-06-30
CN1245172A (zh) 2000-02-23
US5597914A (en) 1997-01-28

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