DK0623018T3 - Process for preparing soft gelatin capsules by a drip process - Google Patents

Process for preparing soft gelatin capsules by a drip process

Info

Publication number
DK0623018T3
DK0623018T3 DK93901686.1T DK93901686T DK0623018T3 DK 0623018 T3 DK0623018 T3 DK 0623018T3 DK 93901686 T DK93901686 T DK 93901686T DK 0623018 T3 DK0623018 T3 DK 0623018T3
Authority
DK
Denmark
Prior art keywords
soft gelatin
drip
gelatin capsules
preparing soft
liquid
Prior art date
Application number
DK93901686.1T
Other languages
Danish (da)
Inventor
Juergen Freidenreich
Juergen Werry
Ursula Schick
Jens-Christian Wunderlich
Original Assignee
Alfatec Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4201178A external-priority patent/DE4201178C2/en
Application filed by Alfatec Pharma Gmbh filed Critical Alfatec Pharma Gmbh
Application granted granted Critical
Publication of DK0623018T3 publication Critical patent/DK0623018T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)

Abstract

The invention concerns a drip-feed method for the manufacture of soft gelatin capsules, the preferably soft or liquid contents being enclosed in soft gelatin which is then solidified in a low-temperature cooling bath containing a chemically inert liquified gas which leaves no biologically undesirable or toxic residues on the capsules. Liquid nitrogen is preferably used as the cooling-bath liquid.
DK93901686.1T 1992-01-17 1993-01-18 Process for preparing soft gelatin capsules by a drip process DK0623018T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4201178A DE4201178C2 (en) 1992-01-17 1992-01-17 Process for the production of soft gelatin capsules by a dropping process
US07/876,863 US5254294A (en) 1992-01-17 1992-04-30 Soft gelatin capsules

Publications (1)

Publication Number Publication Date
DK0623018T3 true DK0623018T3 (en) 1996-03-04

Family

ID=25911045

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93901686.1T DK0623018T3 (en) 1992-01-17 1993-01-18 Process for preparing soft gelatin capsules by a drip process

Country Status (10)

Country Link
EP (1) EP0623018B1 (en)
JP (1) JPH07502912A (en)
AT (1) ATE132036T1 (en)
AU (1) AU670771B2 (en)
CA (1) CA2128243C (en)
DE (1) DE59301262D1 (en)
DK (1) DK0623018T3 (en)
ES (1) ES2083846T3 (en)
GR (1) GR3019424T3 (en)
WO (1) WO1993013761A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU679906B2 (en) 1992-01-17 1997-07-17 Alfatec-Pharma Gmbh Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
DE59812488D1 (en) * 1997-07-09 2005-02-17 Swiss Caps Rechte & Lizenzen METHOD AND DEVICE FOR PRODUCING A MULTILAYER, PHYSIOLOGICALLY COMPATIBLE PHARMACEUTICAL FORM
DE19930030B4 (en) * 1999-06-30 2004-02-19 Meduna Arzneimittel Gmbh Oral dosage form containing CO-3-unsaturated fatty acids
US7264824B1 (en) 2000-04-13 2007-09-04 Meduna Arzneimittel Gmbh Oral dosage form
JP5876695B2 (en) 2011-09-29 2016-03-02 森下仁丹株式会社 Seamless capsule and method for producing the same
JP5989953B1 (en) * 2015-12-28 2016-09-07 森下仁丹株式会社 Seamless capsule containing powdery component and method for producing the same
CN110090599A (en) * 2019-05-20 2019-08-06 武汉大坦智能装备科技有限公司 Multistation pill dripping machine
DE102021107251A1 (en) 2021-03-23 2022-09-29 Technische Universität Dortmund Process for coating particles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1080822A (en) * 1952-05-26 1954-12-14 Trifax N V Chemisch Pharmaceut Method and device for the production of seamless capsules
US5141961A (en) * 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives
CA2165415A1 (en) * 1993-06-18 1994-12-19 Prasad S. Adusumilli Soft-shelled gelatin encapsulated particles
SI1033128T2 (en) * 1993-09-28 2012-02-29 Scherer Gmbh R P Soft gelatin capsule manufacture

Also Published As

Publication number Publication date
AU3254693A (en) 1993-08-03
ES2083846T3 (en) 1996-04-16
DE59301262D1 (en) 1996-02-08
CA2128243A1 (en) 1993-07-22
ATE132036T1 (en) 1996-01-15
JPH07502912A (en) 1995-03-30
EP0623018B1 (en) 1995-12-27
EP0623018A1 (en) 1994-11-09
CA2128243C (en) 1998-09-22
AU670771B2 (en) 1996-08-01
WO1993013761A1 (en) 1993-07-22
GR3019424T3 (en) 1996-06-30

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