DK0618906T3 - Substituerede imidazolderivater og deres fremstilling og anvendelse - Google Patents
Substituerede imidazolderivater og deres fremstilling og anvendelseInfo
- Publication number
- DK0618906T3 DK0618906T3 DK93900200T DK93900200T DK0618906T3 DK 0618906 T3 DK0618906 T3 DK 0618906T3 DK 93900200 T DK93900200 T DK 93900200T DK 93900200 T DK93900200 T DK 93900200T DK 0618906 T3 DK0618906 T3 DK 0618906T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- pct
- preparation
- inden
- dihydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919127050A GB9127050D0 (en) | 1991-12-20 | 1991-12-20 | Substituted imidazole derivatives and their preparation and use |
PCT/FI1992/000349 WO1993013074A1 (en) | 1991-12-20 | 1992-12-18 | Substituted imidazole derivatives and their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0618906T3 true DK0618906T3 (da) | 1999-01-25 |
Family
ID=10706581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93900200T DK0618906T3 (da) | 1991-12-20 | 1992-12-18 | Substituerede imidazolderivater og deres fremstilling og anvendelse |
Country Status (17)
Country | Link |
---|---|
US (1) | US5498623A (da) |
EP (1) | EP0618906B1 (da) |
JP (1) | JP3276371B2 (da) |
AT (1) | ATE165350T1 (da) |
AU (1) | AU664584B2 (da) |
CA (1) | CA2117305C (da) |
DE (1) | DE69225240T2 (da) |
DK (1) | DK0618906T3 (da) |
ES (1) | ES2115046T3 (da) |
FI (1) | FI104968B (da) |
GB (1) | GB9127050D0 (da) |
HK (1) | HK1008962A1 (da) |
HU (1) | HU220043B (da) |
NO (1) | NO304227B1 (da) |
PL (1) | PL172532B1 (da) |
RU (1) | RU2120440C1 (da) |
WO (1) | WO1993013074A1 (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9312669D0 (en) * | 1993-06-18 | 1993-08-04 | Orion Yhtymae Oy | New opticla isomers |
FR2735776B1 (fr) * | 1995-06-22 | 1997-07-18 | Synthelabo | Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique |
GB9520150D0 (en) | 1995-10-03 | 1995-12-06 | Orion Yhtymae Oy | New imidazole derivatives |
US20020143007A1 (en) * | 1996-02-02 | 2002-10-03 | Garvey David S. | Nitrosated and nitrosylated alpha-adrenergic receptor antagonists, compositions and methods of use |
US6469065B1 (en) | 1996-02-02 | 2002-10-22 | Nitromed, Inc. | Nitrosated and nitrosylated α-adrenergic receptor antagonist, compositions and methods of use |
FI20000073A0 (fi) * | 2000-01-14 | 2000-01-14 | Orion Yhtymae Oy | Uusia imidatsolijohdannaisia |
US6388090B2 (en) | 2000-01-14 | 2002-05-14 | Orion Corporation | Imidazole derivatives |
US8188126B2 (en) | 2002-05-16 | 2012-05-29 | Pierre Fabre Medicament | Imidazolic compounds and use thereof as alpha-2 adrenergic receptors |
FI20022007A0 (fi) * | 2002-11-08 | 2002-11-08 | Juvantia Pharma Ltd Oy | Oromukosaalinen valmiste ja menetelmä sen valmistamiseksi |
GB0226076D0 (en) | 2002-11-08 | 2002-12-18 | Rp Scherer Technologies Inc | Improved formulations containing substituted imidazole derivatives |
US8563766B2 (en) | 2009-07-24 | 2013-10-22 | Dsm Pharma Chemicals | Indane derivatives for use as intermediates |
JP2013500983A (ja) * | 2009-07-31 | 2013-01-10 | ドクター・レディーズ・ラボラトリーズ・リミテッド | フィパメゾールの調製 |
EP2502917A1 (en) | 2011-03-17 | 2012-09-26 | Santhera Pharmaceuticals (Schweiz) AG | Solid state crystalline forms of 4-(2-ethyl-5-fluoro-2,3-dihydro-1H-inden-2-yl)-1H-imidazole |
US20200383953A1 (en) * | 2015-11-05 | 2020-12-10 | University Of Louisville Research Foundation, Inc. | Local and regional anesthesia and analgesia |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1282535A (en) * | 1970-03-02 | 1972-07-19 | Pfizer | (2-IMIDAZOLIN-2-YLAMINO)SUBSTITUTED BENZO[b]THIOPHENES |
US3927023A (en) * | 1974-05-24 | 1975-12-16 | Warner Lambert Co | Imidazolyl benzofurans |
US3927018A (en) * | 1974-12-23 | 1975-12-16 | Sandoz Ag | 3-(2-Methyl-1-imidazolyl)-3-phenyl-1-(3H)isobenzofuranones |
IL66242A0 (en) * | 1981-07-23 | 1982-11-30 | Erba Farmitalia | N-imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene,indan and 2-substituted-1-chroman,their preparation and pharmaceutical compositions containing them |
ZW13782A1 (en) * | 1981-07-28 | 1982-10-06 | Reckitt & Colmann Prod Ltd | Imidazoline derivatives |
ES523609A0 (es) * | 1982-07-05 | 1985-03-01 | Erba Farmitalia | Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos. |
GB8409884D0 (en) * | 1984-04-17 | 1984-05-31 | Detexomat Machinery Ltd | Transporting fabric pieces |
GB2167408B (en) * | 1984-11-23 | 1988-05-25 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
FI81092C (fi) * | 1986-05-15 | 1990-09-10 | Farmos Oy | Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat. |
JP2855341B2 (ja) * | 1988-06-10 | 1999-02-10 | 武田薬品工業株式会社 | 新規2―置換クマラン誘導体 |
IL91542A0 (en) * | 1988-10-06 | 1990-04-29 | Erba Carlo Spa | N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them |
GB2225782A (en) * | 1988-12-09 | 1990-06-13 | Farmos Group Limited | Imidazole derivatives useful for treatment of diabetes |
GB9020128D0 (en) * | 1990-09-14 | 1990-10-24 | Reckitt & Colmann Prod Ltd | Imidazoline derivatives |
EP0618864A1 (en) * | 1991-12-23 | 1994-10-12 | Mobil Oil Corporation | Low oxygen transmissive film |
GB9127430D0 (en) * | 1991-12-27 | 1992-02-19 | Scras | Benzofuranylimidazole derivatives |
-
1991
- 1991-12-20 GB GB919127050A patent/GB9127050D0/en active Pending
-
1992
- 1992-12-18 PL PL92304150A patent/PL172532B1/pl unknown
- 1992-12-18 AU AU31605/93A patent/AU664584B2/en not_active Expired
- 1992-12-18 AT AT93900200T patent/ATE165350T1/de active
- 1992-12-18 RU RU94031215/04A patent/RU2120440C1/ru active
- 1992-12-18 ES ES93900200T patent/ES2115046T3/es not_active Expired - Lifetime
- 1992-12-18 US US08/244,932 patent/US5498623A/en not_active Expired - Lifetime
- 1992-12-18 DE DE69225240T patent/DE69225240T2/de not_active Expired - Lifetime
- 1992-12-18 CA CA002117305A patent/CA2117305C/en not_active Expired - Lifetime
- 1992-12-18 DK DK93900200T patent/DK0618906T3/da active
- 1992-12-18 JP JP51146093A patent/JP3276371B2/ja not_active Expired - Lifetime
- 1992-12-18 WO PCT/FI1992/000349 patent/WO1993013074A1/en active IP Right Grant
- 1992-12-18 EP EP93900200A patent/EP0618906B1/en not_active Expired - Lifetime
- 1992-12-18 HU HU9401823A patent/HU220043B/hu unknown
-
1994
- 1994-06-16 FI FI942882A patent/FI104968B/fi not_active IP Right Cessation
- 1994-06-17 NO NO942335A patent/NO304227B1/no not_active IP Right Cessation
-
1998
- 1998-08-05 HK HK98109707A patent/HK1008962A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2117305C (en) | 2003-11-25 |
EP0618906A1 (en) | 1994-10-12 |
EP0618906B1 (en) | 1998-04-22 |
FI942882A0 (fi) | 1994-06-16 |
NO942335L (no) | 1994-06-20 |
AU3160593A (en) | 1993-07-28 |
DE69225240D1 (de) | 1998-05-28 |
US5498623A (en) | 1996-03-12 |
AU664584B2 (en) | 1995-11-23 |
HU9401823D0 (en) | 1994-09-28 |
HUT67548A (en) | 1995-04-28 |
FI942882A (fi) | 1994-06-16 |
WO1993013074A1 (en) | 1993-07-08 |
CA2117305A1 (en) | 1993-07-08 |
RU94031215A (ru) | 1996-04-20 |
GB9127050D0 (en) | 1992-02-19 |
HU220043B (hu) | 2001-10-28 |
ATE165350T1 (de) | 1998-05-15 |
HK1008962A1 (en) | 1999-05-21 |
FI104968B (fi) | 2000-05-15 |
PL172532B1 (en) | 1997-10-31 |
ES2115046T3 (es) | 1998-06-16 |
NO942335D0 (no) | 1994-06-17 |
NO304227B1 (no) | 1998-11-16 |
DE69225240T2 (de) | 1998-08-27 |
RU2120440C1 (ru) | 1998-10-20 |
JPH07506087A (ja) | 1995-07-06 |
JP3276371B2 (ja) | 2002-04-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0618906T3 (da) | Substituerede imidazolderivater og deres fremstilling og anvendelse | |
ES2164657T3 (es) | Derivados aza-biciclicos puenteados como antagonistas de la sustancia p. | |
DK0894084T3 (da) | Kanelsyrederivater og deres anvendelse som integrinantagonister | |
DK0613458T3 (da) | Acykliske ethylendiaminderivater som substans P receptorantagonister | |
NO986055D0 (no) | Nye heterocykliske forbindelser, deres fremstilling, farmas÷ytiske preparat | |
DK0889877T3 (da) | Meta-substituerede phenylenderivater og deres anvendelse som alfav-beta3-integrin-antagonister eller -inhibitorer | |
DK0880517T3 (da) | Quinazolin-forbindelser | |
ES2149777T3 (es) | Derivados de triazol que tienen actividad antifungica. | |
DE69413831T2 (de) | Phenoxyphenylcyclopentenyl-hydroxyharnstoffe | |
ES2059550T3 (es) | Derivados de la bencimidazola, su preparacion y su aplicacion en terapeutica. | |
DE69613783D1 (de) | 4-(6-fluor-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-on-derivate,ihre herstellung und ihre verwendung in der behandlung von psychosen, schizophrenie und angstzuständen | |
FI955707A (fi) | Indolijohdannaiset steroidi-5alfa-reduktaasin inhibiittoreina | |
NO20002154L (no) | Nye heterocykliske substituerte alfa-hydroksykarboksylsyre- derivater | |
UA27738C2 (uk) | 2,3,4,5,6,7-гексагідро-1-[4-[1-[4-(2метоксифеніл)піперазиніл]]-2-фенілбутирил]-1н-азепін або його фармацевтично прийнятна кислотно-адитивна сіль, що мають властивість пов'язувати рецептор 5нт1а, спосіб (варіанти) їх одержання, фармацевтична композиція |