DK0593595T3 - Derivater af inositol, præparater indeholdende dem samt deres anvendelse - Google Patents
Derivater af inositol, præparater indeholdende dem samt deres anvendelseInfo
- Publication number
- DK0593595T3 DK0593595T3 DK92914702T DK92914702T DK0593595T3 DK 0593595 T3 DK0593595 T3 DK 0593595T3 DK 92914702 T DK92914702 T DK 92914702T DK 92914702 T DK92914702 T DK 92914702T DK 0593595 T3 DK0593595 T3 DK 0593595T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- chemical structure
- hydrogen
- inositol
- derivatives
- Prior art date
Links
- 150000004001 inositols Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 abstract 1
- 229960000367 inositol Drugs 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4075—Esters with hydroxyalkyl compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9102068A SE9102068L (sv) | 1991-07-03 | 1991-07-03 | Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav |
PCT/SE1992/000489 WO1993001197A1 (en) | 1991-07-03 | 1992-06-30 | Derivatives of inositol, preparations containing them and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0593595T3 true DK0593595T3 (da) | 2000-06-26 |
Family
ID=20383238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK92914702T DK0593595T3 (da) | 1991-07-03 | 1992-06-30 | Derivater af inositol, præparater indeholdende dem samt deres anvendelse |
Country Status (9)
Country | Link |
---|---|
US (1) | US5306841A (da) |
EP (1) | EP0593595B1 (da) |
JP (1) | JP3102798B2 (da) |
AT (1) | ATE188478T1 (da) |
AU (1) | AU2291592A (da) |
DE (1) | DE69230532T2 (da) |
DK (1) | DK0593595T3 (da) |
SE (1) | SE9102068L (da) |
WO (1) | WO1993001197A1 (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004043396A2 (en) * | 2002-11-09 | 2004-05-27 | Nobex Corporation | Modified carbamate-containing prodrugs and methods of synthesizing same |
US7521481B2 (en) * | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
JP2008520589A (ja) * | 2004-11-17 | 2008-06-19 | ジョアン マクローリン, | シロイノシトール誘導体を含む組成物およびタンパク質凝集障害を治療するための方法 |
US20090170957A1 (en) * | 2005-10-13 | 2009-07-02 | Antonio Cruz | Scyllo-inositol derivatives and their use in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence |
US20070197452A1 (en) * | 2006-02-17 | 2007-08-23 | Mclaurin Joanne | Treatment of amyloid-related diseases |
WO2007101353A1 (en) * | 2006-03-09 | 2007-09-13 | Waratah Pharmaceuticals Inc. | A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation |
CA2652449A1 (en) * | 2006-05-19 | 2007-11-29 | Waratah Pharmaceuticals Inc. | Screening methods for amyloid beta modulators |
US20100173960A1 (en) * | 2006-09-21 | 2010-07-08 | Antonio Cruz | The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases |
EP2091566A4 (en) * | 2006-11-24 | 2011-07-06 | Waratah Pharmaceuticals Inc | COMBINATION THERAPIES AGAINST ALZHEIMER DISEASE AND SIMILAR ILLNESSES |
CA2683580A1 (en) * | 2007-04-12 | 2008-10-23 | Joanne Mclaurin | Treatment of amyotrophic lateral sclerosis |
CA2683548A1 (en) * | 2007-04-12 | 2008-10-23 | Joanne Mclaurin | Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases |
WO2008124940A1 (en) * | 2007-04-12 | 2008-10-23 | Waratah Pharmaceuticals Inc. | Use of cyclohexanehexol derivatives in the treatment of ocular diseases |
CA2683546A1 (en) * | 2007-04-12 | 2008-10-23 | Joanne Mclaurin | Use of cyclohexanehexol derivatives in the treatment of .alpha.-synucleinopathies |
AU2009301603A1 (en) * | 2008-10-09 | 2010-04-15 | Waratah Pharmaceuticals Inc. | Use of scyllo-inositols for the treatment of macular degeneration-related disorders |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4515722A (en) * | 1982-03-30 | 1985-05-07 | Merck & Co., Inc. | Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents |
US4585762A (en) * | 1982-07-30 | 1986-04-29 | Fujisawa Pharmaceutical Co., Ltd. | Phospholipid derivatives, processes for use thereof and pharmaceutical composition of the same |
SE465951B (sv) * | 1984-10-23 | 1991-11-25 | Perstorp Ab | Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav |
SE8605063D0 (sv) * | 1986-11-26 | 1986-11-26 | Matti Siren | Derivatives of cyclohexane |
-
1991
- 1991-07-03 SE SE9102068A patent/SE9102068L/xx unknown
-
1992
- 1992-06-30 AT AT92914702T patent/ATE188478T1/de active
- 1992-06-30 JP JP05502180A patent/JP3102798B2/ja not_active Expired - Fee Related
- 1992-06-30 EP EP92914702A patent/EP0593595B1/en not_active Expired - Lifetime
- 1992-06-30 WO PCT/SE1992/000489 patent/WO1993001197A1/en active IP Right Grant
- 1992-06-30 DK DK92914702T patent/DK0593595T3/da active
- 1992-06-30 US US07/955,708 patent/US5306841A/en not_active Expired - Fee Related
- 1992-06-30 DE DE69230532T patent/DE69230532T2/de not_active Expired - Fee Related
- 1992-06-30 AU AU22915/92A patent/AU2291592A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2291592A (en) | 1993-02-11 |
SE9102068L (sv) | 1993-01-04 |
EP0593595B1 (en) | 2000-01-05 |
DE69230532D1 (de) | 2000-02-10 |
DE69230532T2 (de) | 2000-08-24 |
US5306841A (en) | 1994-04-26 |
JP3102798B2 (ja) | 2000-10-23 |
EP0593595A1 (en) | 1994-04-27 |
ATE188478T1 (de) | 2000-01-15 |
SE9102068D0 (sv) | 1991-07-03 |
WO1993001197A1 (en) | 1993-01-21 |
JPH06509092A (ja) | 1994-10-13 |
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