DK0589488T3 - I det væsentlige optisk rent (-)-cimaterol og dens syreadditionssalte samt dens anvendelse som lægemiddel eller vækstfremmer - Google Patents

I det væsentlige optisk rent (-)-cimaterol og dens syreadditionssalte samt dens anvendelse som lægemiddel eller vækstfremmer

Info

Publication number
DK0589488T3
DK0589488T3 DK93117935.2T DK93117935T DK0589488T3 DK 0589488 T3 DK0589488 T3 DK 0589488T3 DK 93117935 T DK93117935 T DK 93117935T DK 0589488 T3 DK0589488 T3 DK 0589488T3
Authority
DK
Denmark
Prior art keywords
cimaterol
drug
well
acid addition
addition salts
Prior art date
Application number
DK93117935.2T
Other languages
Danish (da)
English (en)
Inventor
Wolfgang Dr Dipl-Chem Resemann
Adolf Duerr
Guenther Prof Dr Engelhardt
John Francis Dr Quirke
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Application granted granted Critical
Publication of DK0589488T3 publication Critical patent/DK0589488T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/111Aromatic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/59Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Pain & Pain Management (AREA)
  • Birds (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93117935.2T 1990-05-04 1991-04-26 I det væsentlige optisk rent (-)-cimaterol og dens syreadditionssalte samt dens anvendelse som lægemiddel eller vækstfremmer DK0589488T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4014252A DE4014252A1 (de) 1990-05-04 1990-05-04 Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer

Publications (1)

Publication Number Publication Date
DK0589488T3 true DK0589488T3 (da) 1998-05-04

Family

ID=6405664

Family Applications (2)

Application Number Title Priority Date Filing Date
DK91106774.2T DK0455155T3 (da) 1990-05-04 1991-04-26 Adskillelse af enantiomere af cimaterol
DK93117935.2T DK0589488T3 (da) 1990-05-04 1991-04-26 I det væsentlige optisk rent (-)-cimaterol og dens syreadditionssalte samt dens anvendelse som lægemiddel eller vækstfremmer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK91106774.2T DK0455155T3 (da) 1990-05-04 1991-04-26 Adskillelse af enantiomere af cimaterol

Country Status (27)

Country Link
US (4) US5248695A (es)
EP (2) EP0455155B1 (es)
JP (1) JP2944777B2 (es)
KR (1) KR0183024B1 (es)
AR (1) AR247728A1 (es)
AT (2) ATE124932T1 (es)
AU (1) AU645313B2 (es)
BG (1) BG60743B1 (es)
CA (1) CA2041818C (es)
CZ (1) CZ286389B6 (es)
DE (3) DE4014252A1 (es)
DK (2) DK0455155T3 (es)
ES (2) ES2109412T3 (es)
FI (1) FI109600B (es)
GR (2) GR3017064T3 (es)
HU (1) HU214335B (es)
ID (1) ID966B (es)
IE (2) IE80651B1 (es)
IL (1) IL98030A (es)
NO (1) NO174803B (es)
NZ (1) NZ238032A (es)
PT (1) PT97544B (es)
RU (1) RU2002737C1 (es)
SG (1) SG45439A1 (es)
SK (1) SK279258B6 (es)
TW (1) TW197415B (es)
ZA (1) ZA913337B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4014252A1 (de) * 1990-05-04 1991-11-07 Boehringer Ingelheim Vetmed Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer
GB9107196D0 (en) * 1991-04-05 1991-05-22 Sandoz Ag Improvements in or relating to organic compounds
GB2289842B (en) * 1991-04-05 1996-01-31 Sepracor Inc Improved use of ß2 bronchodilator drugs
CA2247953A1 (en) * 1996-01-29 1997-07-31 E. Charles Pesterfield Jr. Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists
EP0979081A4 (en) 1997-04-30 2003-05-02 Bridge Pharma Inc COMPOSITION AND METHODS USING EUTOMER
EP1787529A3 (en) * 1997-04-30 2009-11-18 Courage Corporation Pty Ltd. Composition and methods using an eutomer
ZA994264B (en) 1998-07-01 2000-01-25 Warner Lambert Co Stereoisomers with high affinity for adrenergic receptors.
US7232837B2 (en) 1999-06-29 2007-06-19 Mcneil-Ppc, Inc. Stereoisomers with high affinity for adrenergic receptors
HUP0300832A2 (hu) * 2000-04-27 2003-08-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Új, lassú hatású bétamimetikumok, eljárás előállításukra és alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények
US20030162459A1 (en) * 2002-02-27 2003-08-28 Osbon Robert Lindsay Method for producing a nonwoven fabric with enhanced characteristics
WO2004103057A2 (en) * 2003-05-15 2004-12-02 The University Of Georgia Research Foundation, Inc. Compositions and methods for inducing adipose tissue cell death
BRPI0410805A (pt) * 2003-09-09 2006-06-27 Fumapharm Ag uso de derivados do ácido fumárico para tratamento da insuficiência cardìaca e asma
SG124283A1 (en) * 2004-03-24 2006-08-30 Trusted Hub Ltd Document signature method & system
AR054249A1 (es) * 2005-04-13 2007-06-13 Astion Dev As Tratamiento de enfermedades del tejido conectivo de la piel
US20090181369A1 (en) * 2005-05-27 2009-07-16 George Q Daley Methods for the Treatment of Disease
WO2006138243A2 (en) * 2005-06-13 2006-12-28 University Of Vermont And State Agricultural College Inhibition of creatine uptake to promote weight loss
PE20151158A1 (es) 2012-12-03 2015-08-14 Pfizer Moduladores selectivos del receptor de androgenos novedosos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL136601C (es) * 1967-06-15
US4119710A (en) * 1972-12-18 1978-10-10 Boehringer Ingelheim Gmbh Bronchospasmolytic 1-(p-amino-phenyl)-2-amino-ethanols-(1) and salts
US4407819A (en) * 1980-08-25 1983-10-04 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for the depression of fat deposition in warm blooded animals
US4814350A (en) * 1986-09-10 1989-03-21 American Cyanamid Company Method of treating diabetes with 5-[1-hydroxy-2-(isopropylamino)ethyl]anthranilonitrile
US4792546A (en) * 1986-12-05 1988-12-20 American Cyanamid Company Method for increasing weight gains and reducing deposition of fat in animals
DE4014252A1 (de) * 1990-05-04 1991-11-07 Boehringer Ingelheim Vetmed Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer

Also Published As

Publication number Publication date
NZ238032A (en) 1996-02-27
CA2041818C (en) 2003-02-11
FI912151A (fi) 1991-11-05
EP0589488B1 (de) 1997-09-17
CA2041818A1 (en) 1991-11-05
DE59105957D1 (de) 1995-08-17
HU911502D0 (en) 1991-11-28
GR3017064T3 (en) 1995-11-30
PT97544B (pt) 1998-08-31
US5292753A (en) 1994-03-08
CS129291A3 (en) 1991-11-12
US5395957A (en) 1995-03-07
EP0589488A1 (de) 1994-03-30
GR3025547T3 (en) 1998-03-31
ATE158277T1 (de) 1997-10-15
FI109600B (fi) 2002-09-13
US5648386A (en) 1997-07-15
DE4014252A1 (de) 1991-11-07
IE911507A1 (en) 1991-11-06
NO174803C (es) 1994-07-13
CZ286389B6 (cs) 2000-03-15
DK0455155T3 (da) 1995-11-13
IE69017B1 (en) 1996-07-24
BG60743B1 (bg) 1996-02-29
US5248695A (en) 1993-09-28
JP2944777B2 (ja) 1999-09-06
ATE124932T1 (de) 1995-07-15
SG45439A1 (en) 1998-01-16
AU7611191A (en) 1991-11-07
ES2109412T3 (es) 1998-01-16
IE80651B1 (en) 1998-11-04
FI912151A0 (fi) 1991-05-03
HU214335B (hu) 1998-03-02
EP0455155B1 (de) 1995-07-12
JPH04225944A (ja) 1992-08-14
ZA913337B (en) 1993-01-27
DE59108853D1 (de) 1997-10-23
NO174803B (no) 1994-04-05
TW197415B (es) 1993-01-01
SK279258B6 (sk) 1998-08-05
RU2002737C1 (ru) 1993-11-15
ES2075255T3 (es) 1995-10-01
IL98030A (en) 1995-12-31
KR0183024B1 (ko) 1999-05-15
AU645313B2 (en) 1994-01-13
ID966B (id) 1996-09-30
NO911746L (no) 1991-11-05
IL98030A0 (en) 1992-06-21
HUT60999A (en) 1992-11-30
BG94342A (en) 1994-06-30
PT97544A (pt) 1992-01-31
KR910019966A (ko) 1991-12-19
NO911746D0 (no) 1991-05-03
AR247728A1 (es) 1995-03-31
EP0455155A1 (de) 1991-11-06

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