DK0578728T3 - Inhibitorer for aggregering af blodplader, hvilke inhibitorer har høj specificitet for GP IIbIIIa - Google Patents

Inhibitorer for aggregering af blodplader, hvilke inhibitorer har høj specificitet for GP IIbIIIa

Info

Publication number
DK0578728T3
DK0578728T3 DK92909119T DK92909119T DK0578728T3 DK 0578728 T3 DK0578728 T3 DK 0578728T3 DK 92909119 T DK92909119 T DK 92909119T DK 92909119 T DK92909119 T DK 92909119T DK 0578728 T3 DK0578728 T3 DK 0578728T3
Authority
DK
Denmark
Prior art keywords
iibiiia
platelet aggregation
high specificity
aggregation inhibitors
inhibitors
Prior art date
Application number
DK92909119T
Other languages
English (en)
Inventor
P Burnier John
Thomas Gadek
Robert Mcdowell
John P Burnier
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK0578728T3 publication Critical patent/DK0578728T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein
DK92909119T 1991-04-05 1992-04-03 Inhibitorer for aggregering af blodplader, hvilke inhibitorer har høj specificitet for GP IIbIIIa DK0578728T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68180291A 1991-04-05 1991-04-05
PCT/US1992/002731 WO1992017492A1 (en) 1991-04-05 1992-04-03 PLATELET AGGREGATION INHIBITORS HAVING HIGH SPECIFICITY FOR GP IIbIII¿a?

Publications (1)

Publication Number Publication Date
DK0578728T3 true DK0578728T3 (da) 1999-04-12

Family

ID=24736888

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92909119T DK0578728T3 (da) 1991-04-05 1992-04-03 Inhibitorer for aggregering af blodplader, hvilke inhibitorer har høj specificitet for GP IIbIIIa

Country Status (8)

Country Link
US (2) US5493007A (da)
EP (1) EP0578728B1 (da)
JP (1) JPH06509551A (da)
AU (1) AU666853B2 (da)
CA (1) CA2106314A1 (da)
DE (1) DE69226077T2 (da)
DK (1) DK0578728T3 (da)
WO (1) WO1992017492A1 (da)

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US9273093B2 (en) * 2012-10-11 2016-03-01 Protagonist Therapeutics, Inc. α4β7 peptide dimer antagonists
HUE057168T2 (hu) 2013-03-15 2022-04-28 Protagonist Therapeutics Inc A hepcidin analógjai és ezek alkalmazása
US20140294902A1 (en) * 2013-04-02 2014-10-02 Protagonist Therapeutics, Inc. Novel a4b7 peptide antagonists
SI3143037T1 (sl) 2014-05-16 2021-11-30 Protagonist Therapeutics, Inc. Antagonisti integrin alpha4beta7 tioeterskih peptidov
US9624268B2 (en) 2014-07-17 2017-04-18 Protagonist Therapeutics, Inc. Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
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Also Published As

Publication number Publication date
WO1992017492A1 (en) 1992-10-15
EP0578728A1 (en) 1994-01-19
US5756452A (en) 1998-05-26
DE69226077D1 (de) 1998-08-06
CA2106314A1 (en) 1992-10-06
JPH06509551A (ja) 1994-10-27
EP0578728B1 (en) 1998-07-01
DE69226077T2 (de) 1998-12-03
US5493007A (en) 1996-02-20
AU666853B2 (en) 1996-02-29
AU1982292A (en) 1992-11-02

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