DK0578521T3 - New peptide derivatives having bradykinin antagonistic effect, process for the preparation of the derivatives and pharmaceutical compositions containing them - Google Patents

New peptide derivatives having bradykinin antagonistic effect, process for the preparation of the derivatives and pharmaceutical compositions containing them

Info

Publication number
DK0578521T3
DK0578521T3 DK93401552.0T DK93401552T DK0578521T3 DK 0578521 T3 DK0578521 T3 DK 0578521T3 DK 93401552 T DK93401552 T DK 93401552T DK 0578521 T3 DK0578521 T3 DK 0578521T3
Authority
DK
Denmark
Prior art keywords
derivatives
preparation
pharmaceutical compositions
compositions containing
antagonistic effect
Prior art date
Application number
DK93401552.0T
Other languages
Danish (da)
Inventor
Jean-Luc Fauchere
Emmanuel Canet
Joseph Paladino
Christophe Thurieau
Nathalie Kucharczyk
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0578521T3 publication Critical patent/DK0578521T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Compounds of formula (I): <IMAGE> in which X, X', A1, A2, A3, A4, A5, A6, A7, A8, A 9 and Y are as defined in the description. Medications.
DK93401552.0T 1992-06-18 1993-06-17 New peptide derivatives having bradykinin antagonistic effect, process for the preparation of the derivatives and pharmaceutical compositions containing them DK0578521T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9207378A FR2692581B1 (en) 1992-06-18 1992-06-18 New peptide derivatives with bradykinin antagonist activity, their preparation process and the pharmaceutical compositions containing them.

Publications (1)

Publication Number Publication Date
DK0578521T3 true DK0578521T3 (en) 1996-12-09

Family

ID=9430857

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93401552.0T DK0578521T3 (en) 1992-06-18 1993-06-17 New peptide derivatives having bradykinin antagonistic effect, process for the preparation of the derivatives and pharmaceutical compositions containing them

Country Status (12)

Country Link
EP (1) EP0578521B1 (en)
JP (1) JP2589937B2 (en)
AT (1) ATE141615T1 (en)
AU (1) AU660809B2 (en)
CA (1) CA2098655A1 (en)
DE (1) DE69304155T2 (en)
DK (1) DK0578521T3 (en)
ES (1) ES2091570T3 (en)
FR (1) FR2692581B1 (en)
GR (1) GR3021472T3 (en)
NZ (1) NZ247914A (en)
ZA (1) ZA934389B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE269310T1 (en) * 1994-10-27 2004-07-15 Fujisawa Pharmaceutical Co PYRIDOPYRIMIDINONES, QUINOLINES AND FANNED N-HETEROCYCLES AS BRADYKININ ANTAGONISTS
FR2739553B1 (en) 1995-10-06 1998-01-02 Oreal USE OF BRADYKININE ANTAGONISTS TO STIMULATE OR INDUCE HAIR GROWTH AND / OR STOP THE HAIR LOSS
DE19612067A1 (en) * 1996-03-27 1997-10-02 Hoechst Ag Use of bradykinin antagonists for the manufacture of medicaments for the treatment of chronic fibrogenetic liver diseases and acute liver diseases
DE19642289A1 (en) 1996-10-14 1998-04-16 Hoechst Ag Use of bradykinin antagonists for the manufacture of medicaments for the treatment and prevention of Alzheimer's disease
US7105172B1 (en) 1999-11-18 2006-09-12 Bolla John D Treatment of rosacea
JP6424950B2 (en) * 2015-03-24 2018-11-21 日立金属株式会社 Composite cable, composite harness, and vehicle

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
MX9100717A (en) * 1990-08-24 1992-04-01 Syntex Inc BRADIQUININE ANTAGONISTS
FR2686343B1 (en) * 1992-01-17 1994-03-11 Adir Cie NOVEL PSEUDOPEPTIDE DERIVATIVES WITH ANTAGONIST ACTIVITY OF BRADYKININE, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
FR2692581A1 (en) 1993-12-24
AU660809B2 (en) 1995-07-06
CA2098655A1 (en) 1993-12-19
ES2091570T3 (en) 1996-11-01
ZA934389B (en) 1994-01-17
DE69304155D1 (en) 1996-09-26
EP0578521B1 (en) 1996-08-21
JPH0687891A (en) 1994-03-29
ATE141615T1 (en) 1996-09-15
NZ247914A (en) 1994-12-22
JP2589937B2 (en) 1997-03-12
DE69304155T2 (en) 1997-03-20
EP0578521A1 (en) 1994-01-12
GR3021472T3 (en) 1997-01-31
FR2692581B1 (en) 1994-08-19
AU4128793A (en) 1993-12-23

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