DK0576439T3 - Monoklonalt antistof mod LPS-kerne - Google Patents

Monoklonalt antistof mod LPS-kerne

Info

Publication number
DK0576439T3
DK0576439T3 DK92904901T DK92904901T DK0576439T3 DK 0576439 T3 DK0576439 T3 DK 0576439T3 DK 92904901 T DK92904901 T DK 92904901T DK 92904901 T DK92904901 T DK 92904901T DK 0576439 T3 DK0576439 T3 DK 0576439T3
Authority
DK
Denmark
Prior art keywords
thr
leu
tyr
arg
ser
Prior art date
Application number
DK92904901T
Other languages
English (en)
Inventor
Hermann Gram
Padova Franco Di
George Robin Barclay
Ian Raymond Poxton
Original Assignee
Common Services Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Common Services Agency filed Critical Common Services Agency
Application granted granted Critical
Publication of DK0576439T3 publication Critical patent/DK0576439T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK92904901T 1991-03-13 1992-02-22 Monoklonalt antistof mod LPS-kerne DK0576439T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919105292A GB9105292D0 (en) 1991-03-13 1991-03-13 Improvements in or relating to organic compounds
PCT/EP1992/000380 WO1992016624A1 (en) 1991-03-13 1992-02-22 Monoclonal antibody against lps core

Publications (1)

Publication Number Publication Date
DK0576439T3 true DK0576439T3 (da) 1999-11-01

Family

ID=10691487

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92904901T DK0576439T3 (da) 1991-03-13 1992-02-22 Monoklonalt antistof mod LPS-kerne

Country Status (10)

Country Link
EP (1) EP0576439B1 (da)
JP (1) JP3328277B2 (da)
AT (1) ATE179753T1 (da)
AU (1) AU1261192A (da)
CA (1) CA2105979C (da)
DE (1) DE69229110T2 (da)
DK (1) DK0576439T3 (da)
ES (1) ES2131526T3 (da)
GB (1) GB9105292D0 (da)
WO (1) WO1992016624A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU585200B2 (en) * 1983-05-06 1989-06-15 Velos Group Monoclonal antibodies reactive with endotoxin core
IL104782A0 (en) * 1992-02-19 1993-06-10 Schering Corp Cloning and expression of humanized monoclonal antibodies against human interleukin-4
US6749831B1 (en) 1997-05-16 2004-06-15 Medical Defense Technology, Llc Vaccine against lipopolysaccharide core
EP1521776A2 (en) 2002-07-04 2005-04-13 Oncomab Gmbh Neoplasm specific antibodies and uses thereof
DE10311248A1 (de) 2003-03-14 2004-09-30 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper
DE10353175A1 (de) 2003-11-14 2005-06-16 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper mit fettsenkender Wirkung
EP1531162A1 (en) 2003-11-14 2005-05-18 Heinz Vollmers Adenocarcinoma specific antibody SAM-6, and uses thereof
ES2684696T3 (es) * 2009-04-27 2018-10-04 Immuron Limited Preparación de inmunoglobulina enriquecida con anti-LPS para su uso en el tratamiento y/o la profilaxis de esteatohepatitis no alcohólica
DK2605791T3 (da) 2010-08-17 2017-06-19 Immuron Ltd Anti-lps-beriget immunoglobulinpræparat til anvendelse i behandling og/eller profylakse af en patologisk lidelse
DE102011006809A1 (de) 2011-04-05 2012-10-11 Freistaat Bayern vertreten durch die Julius-Maximilians-Universität Würzburg Verwendung eines Mittels aus Antikörpern und/oder Insulin-like growth factor-Antagonisten
DE102011006781A1 (de) * 2011-04-05 2012-10-11 Mat-Malta Advanced Technologies Limited Antikörperprodukt, umfassend n spezifische Antikörper
KR20180101341A (ko) * 2015-11-10 2018-09-12 비스테라, 인크. 리포폴리사카라이드에 특이적으로 결합하는 항체 분자-약물 접합체 및 그의 용도
US11890319B2 (en) 2017-01-18 2024-02-06 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
JP2023521319A (ja) 2020-04-03 2023-05-24 ビステラ， インコーポレイテッド 抗体分子－薬物コンジュゲートおよびその使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU585200B2 (en) * 1983-05-06 1989-06-15 Velos Group Monoclonal antibodies reactive with endotoxin core
EP0183876A1 (en) * 1984-11-27 1986-06-11 The Board Of Trustees Of The Leland Stanford Junior University Monoclonal antibodies for endotoxin core and their use
GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product
FR2606421B1 (fr) * 1986-11-12 1990-01-26 Roussel Uclaf Anticorps monoclonaux antigram (-) procede de preparation et applications
GB2218703B (en) * 1988-05-10 1992-10-28 Sumitomo Chemical Co Human monoclonal antibody to p.aeruginosa: its production and use
JPH04500601A (ja) * 1988-09-19 1992-02-06 シタス　コーポレイション グラム陰性細菌エンドトキシンブロッキングモノクローナル抗体

Also Published As

Publication number Publication date
AU1261192A (en) 1992-10-21
ES2131526T3 (es) 1999-08-01
DE69229110T2 (de) 1999-11-25
CA2105979A1 (en) 1992-09-14
WO1992016624A1 (en) 1992-10-01
ATE179753T1 (de) 1999-05-15
DE69229110D1 (de) 1999-06-10
CA2105979C (en) 2003-05-13
EP0576439A1 (en) 1994-01-05
EP0576439B1 (en) 1999-05-06
JP3328277B2 (ja) 2002-09-24
JPH06505867A (ja) 1994-07-07
GB9105292D0 (en) 1991-04-24

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