DK0521550T3 - Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derfor - Google Patents
Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derforInfo
- Publication number
- DK0521550T3 DK0521550T3 DK92201851.0T DK92201851T DK0521550T3 DK 0521550 T3 DK0521550 T3 DK 0521550T3 DK 92201851 T DK92201851 T DK 92201851T DK 0521550 T3 DK0521550 T3 DK 0521550T3
- Authority
- DK
- Denmark
- Prior art keywords
- compound
- vitamin
- group
- preparation
- relates
- Prior art date
Links
- 229930003316 Vitamin D Natural products 0.000 title abstract 4
- -1 Vitamin D compound Chemical class 0.000 title abstract 4
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 4
- 235000019166 vitamin D Nutrition 0.000 title abstract 4
- 239000011710 vitamin D Substances 0.000 title abstract 4
- 229940046008 vitamin d Drugs 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- BNRNAKTVFSZAFA-UHFFFAOYSA-N hydrindane Chemical compound C1CCCC2CCCC21 BNRNAKTVFSZAFA-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/53—Organo-phosphine oxides; Organo-phosphine thioxides
- C07F9/532—Cycloaliphatic phosphine oxides or thioxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91201746 | 1991-07-05 | ||
| EP92200154 | 1992-01-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0521550T3 true DK0521550T3 (da) | 1996-11-04 |
Family
ID=26129316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92201851.0T DK0521550T3 (da) | 1991-07-05 | 1992-06-24 | Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derfor |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US5403940A (da) |
| EP (1) | EP0521550B1 (da) |
| JP (1) | JP3342047B2 (da) |
| AT (1) | ATE143007T1 (da) |
| AU (1) | AU650148B2 (da) |
| CA (1) | CA2072915C (da) |
| DE (1) | DE69213844T2 (da) |
| DK (1) | DK0521550T3 (da) |
| ES (1) | ES2093180T3 (da) |
| GR (1) | GR3022053T3 (da) |
| IL (1) | IL102385A (da) |
| NZ (1) | NZ243409A (da) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1333616C (en) * | 1989-03-09 | 1994-12-20 | Hector F. Deluca | 19-nor-vitamin d compounds |
| US20040009958A1 (en) * | 1991-01-08 | 2004-01-15 | Bone Care International, Inc. | Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2 |
| US5830885A (en) * | 1992-03-12 | 1998-11-03 | The Johns Hopkins University | Antiproliferative vitamin D3 hybrids |
| DE4220757A1 (de) * | 1992-06-24 | 1994-01-05 | Schering Ag | Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln |
| GB9220272D0 (en) * | 1992-09-25 | 1992-11-11 | Leo Pharm Prod Ltd | Chemical compounds |
| GB9220439D0 (en) * | 1992-09-28 | 1992-11-11 | Leo Pharm Prod Ltd | Chemical compounds |
| TW267161B (da) * | 1992-11-20 | 1996-01-01 | Hoffmann La Roche | |
| US5449668A (en) * | 1993-06-04 | 1995-09-12 | Duphar International Research B.V. | Vitamin D compounds and method of preparing these compounds |
| US5763429A (en) * | 1993-09-10 | 1998-06-09 | Bone Care International, Inc. | Method of treating prostatic diseases using active vitamin D analogues |
| US5565589A (en) * | 1993-11-03 | 1996-10-15 | Wisconsin Alumni Research Foundation | 17-formyl-5,6-trans-vitamin D compounds |
| US6121469A (en) | 1993-12-23 | 2000-09-19 | The Regents Of The University Of California | Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs |
| DE69508895T2 (de) * | 1994-12-14 | 1999-10-21 | Duphar Int Res | Vitamin-D-Derivate und Verfahren zur Herstellung dieser Verbindungen |
| US20020183288A1 (en) * | 1995-04-03 | 2002-12-05 | Bone Care International, Inc. | Method for treating and preventing hyperparathyroidism |
| US6242434B1 (en) * | 1997-08-08 | 2001-06-05 | Bone Care International, Inc. | 24-hydroxyvitamin D, analogs and uses thereof |
| US20040043971A1 (en) * | 1995-04-03 | 2004-03-04 | Bone Care International, Inc. | Method of treating and preventing hyperparathyroidism with active vitamin D analogs |
| CA2175881A1 (en) * | 1995-05-09 | 1996-11-10 | Andrzej Kutner | Vitamin d compounds and methods of preparing these compounds |
| GB9607034D0 (en) * | 1996-04-03 | 1996-06-05 | Leo Pharm Prod Ltd | Chemical compounds |
| US6566353B2 (en) * | 1996-12-30 | 2003-05-20 | Bone Care International, Inc. | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
| US20020128240A1 (en) * | 1996-12-30 | 2002-09-12 | Bone Care International, Inc. | Treatment of hyperproliferative diseases using active vitamin D analogues |
| HUP0002454A2 (hu) * | 1997-02-13 | 2000-12-28 | Bone Care International, Inc. | D-Vitamin-molekularésszel rendelkező konjugátumok és ilyen konjugátumokat tartalmazó gyógyászati készítmények |
| US20030129194A1 (en) * | 1997-02-13 | 2003-07-10 | Bone Care International, Inc. | Targeted therapeutic delivery of vitamin D compounds |
| US6359152B2 (en) | 1997-07-21 | 2002-03-19 | Wisconsin Alumni Research Foundation | 18-substituted-19-nor-vitamin D compounds |
| US5939406A (en) | 1997-07-21 | 1999-08-17 | Wisconsin Alumni Research Foundation | 18-substituted-19-nor-vitamin D compounds |
| US6087350A (en) * | 1997-08-29 | 2000-07-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of pretreatment chemicals to enhance efficacy of cytotoxic agents |
| AU1022999A (en) | 1997-09-08 | 1999-03-29 | F. Hoffmann-La Roche Ag | 1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs |
| AU762481C (en) | 1998-03-27 | 2004-08-19 | Oregon Health Sciences University | Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders |
| WO2002006218A2 (en) * | 2000-07-18 | 2002-01-24 | Bone Care International, Inc. | STABILIZED 1α-HYDROXY VITAMIN D |
| DE10129108A1 (de) * | 2001-06-16 | 2003-01-02 | Harman Becker Automotive Sys | Verfahren und Schaltungsanordnung zur Datenübertragung |
| WO2003026445A1 (en) * | 2001-09-27 | 2003-04-03 | The Coca-Cola Company | Vitamin fortification of foodstuffs |
| US7148211B2 (en) * | 2002-09-18 | 2006-12-12 | Genzyme Corporation | Formulation for lipophilic agents |
| US20040053895A1 (en) * | 2002-09-18 | 2004-03-18 | Bone Care International, Inc. | Multi-use vessels for vitamin D formulations |
| US20060003950A1 (en) * | 2004-06-30 | 2006-01-05 | Bone Care International, Inc. | Method of treating prostatic diseases using a combination of vitamin D analogues and other agents |
| US7094775B2 (en) * | 2004-06-30 | 2006-08-22 | Bone Care International, Llc | Method of treating breast cancer using a combination of vitamin D analogues and other agents |
| NZ563270A (en) | 2005-05-10 | 2010-11-26 | Dermipsor Ltd | Calcipotriol, polyethylene oxide topical compositions for the treatment of hyperproliferative epidermal diseases |
| JP2008540513A (ja) * | 2005-05-10 | 2008-11-20 | ダーミプソル リミテッド | スキンケアのための組成物及び方法 |
| WO2007070853A2 (en) * | 2005-12-14 | 2007-06-21 | Digital Signal Corporation | System and method for tracking eyeball motion |
| KR20170096238A (ko) * | 2009-01-27 | 2017-08-23 | 베르그 엘엘씨 | 화학요법과 연관된 부작용을 경감시키기 위한 비타민 ｄ３ 및 이의 유사물 |
| JP5978130B2 (ja) | 2009-08-14 | 2016-08-24 | バーグ エルエルシー | 脱毛症を治療するためのビタミンｄ３およびその類似体 |
| EP3003497B1 (en) | 2013-05-29 | 2024-02-14 | BPGbio, Inc. | Preventing or mitigating chemotherapy induced alopecia using vitamin d |
| WO2017209934A1 (en) | 2016-05-13 | 2017-12-07 | Case Western Reserve University | Autophagy activators for treating or preventing skin injury |
| US9989699B2 (en) | 2016-10-27 | 2018-06-05 | Corning Incorporated | Low bend loss single mode optical fiber |
| CN113056473A (zh) | 2018-09-07 | 2021-06-29 | 达特茅斯学院托管理事会 | C19支架和甾体及其使用和制造方法 |
| US11512107B2 (en) | 2018-09-07 | 2022-11-29 | Trustees Of Dartmouth College | Methods for assembly of tetracyclic compounds by stereoselective C9-C10 bond formation |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617297A (en) * | 1982-02-12 | 1986-10-14 | Hoffmann-La Roche Inc. | Method of treating disease states by the administration of 1α,25,26-trihydroxycholecalciferol |
| US4508651A (en) * | 1983-03-21 | 1985-04-02 | Hoffmann-La Roche Inc. | Synthesis of 1α,25-dihydroxyergocalciferol |
| US4613594A (en) * | 1984-11-16 | 1986-09-23 | Hoffmann-La Roche Inc. | Fluorinated vitamin D3 compounds |
| US4612308A (en) * | 1984-11-29 | 1986-09-16 | Hoffmann-La Roche Inc. | 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers |
| EP0205025A1 (en) * | 1985-05-27 | 1986-12-17 | Sumitomo Pharmaceuticals Company, Limited | Fluorine derivatives of vitamin D3 and cell differentiation-inducing agents containing the same as an active ingredient |
| US4755329A (en) * | 1985-06-10 | 1988-07-05 | Wisconsin Alumni Research Foundation | Process and intermediates for preparing 1α-hydroxyvitamin D compounds |
| AU603340B2 (en) * | 1985-08-02 | 1990-11-15 | Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) | Novel vitamin d analogues |
| IL77668A (en) * | 1986-01-21 | 1989-03-31 | Teva Pharma | Production of cholecalciferol derivatives and novel intermediates used therefor |
| US4804502A (en) * | 1988-01-20 | 1989-02-14 | Hoffmann-La Roche Inc. | Vitamin D compounds |
| NZ232734A (en) * | 1989-03-09 | 1991-11-26 | Wisconsin Alumni Res Found | 19-nor vitamin d derivatives and pharmaceutical compositions |
| CA1333616C (en) * | 1989-03-09 | 1994-12-20 | Hector F. Deluca | 19-nor-vitamin d compounds |
| US5246925A (en) * | 1989-03-09 | 1993-09-21 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D compounds for use in treating hyperparathyroidism |
| US5449668A (en) * | 1993-06-04 | 1995-09-12 | Duphar International Research B.V. | Vitamin D compounds and method of preparing these compounds |
| US5617297A (en) * | 1995-09-25 | 1997-04-01 | National Semiconductor Corporation | Encapsulation filler technology for molding active electronics components such as IC cards or PCMCIA cards |
-
1992
- 1992-06-24 ES ES92201851T patent/ES2093180T3/es not_active Expired - Lifetime
- 1992-06-24 DK DK92201851.0T patent/DK0521550T3/da active
- 1992-06-24 AT AT92201851T patent/ATE143007T1/de not_active IP Right Cessation
- 1992-06-24 EP EP92201851A patent/EP0521550B1/en not_active Expired - Lifetime
- 1992-06-24 DE DE69213844T patent/DE69213844T2/de not_active Expired - Fee Related
- 1992-06-29 AU AU18649/92A patent/AU650148B2/en not_active Ceased
- 1992-07-01 NZ NZ243409A patent/NZ243409A/en not_active IP Right Cessation
- 1992-07-02 CA CA002072915A patent/CA2072915C/en not_active Expired - Fee Related
- 1992-07-02 IL IL10238592A patent/IL102385A/xx not_active IP Right Cessation
- 1992-07-02 JP JP19928792A patent/JP3342047B2/ja not_active Expired - Fee Related
-
1994
- 1994-01-12 US US08/180,463 patent/US5403940A/en not_active Expired - Lifetime
- 1994-11-01 US US08/333,305 patent/US5637742A/en not_active Expired - Fee Related
-
1996
- 1996-12-17 GR GR960403487T patent/GR3022053T3/el unknown
-
1997
- 1997-02-13 US US08/799,346 patent/US6072062A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL102385A (en) | 1996-09-12 |
| DE69213844D1 (de) | 1996-10-24 |
| GR3022053T3 (en) | 1997-03-31 |
| ATE143007T1 (de) | 1996-10-15 |
| US6072062A (en) | 2000-06-06 |
| AU1864992A (en) | 1993-01-07 |
| NZ243409A (en) | 1995-02-24 |
| EP0521550A3 (en) | 1993-06-16 |
| US5637742A (en) | 1997-06-10 |
| DE69213844T2 (de) | 1997-04-10 |
| IL102385A0 (en) | 1993-01-14 |
| US5403940A (en) | 1995-04-04 |
| EP0521550B1 (en) | 1996-09-18 |
| JP3342047B2 (ja) | 2002-11-05 |
| EP0521550A2 (en) | 1993-01-07 |
| CA2072915A1 (en) | 1993-01-06 |
| JPH05221961A (ja) | 1993-08-31 |
| CA2072915C (en) | 2005-11-01 |
| AU650148B2 (en) | 1994-06-09 |
| ES2093180T3 (es) | 1996-12-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0521550T3 (da) | Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derfor | |
| FI945703A (fi) | 3,4,4-trisybstituoitujen piperidinyyli-N-alkyylikarboksylaattien ja välituotteiden valmistus | |
| AU6347294A (en) | Vitamin D compounds, intermediates in preparation thereof and method of preparing these compounds | |
| DK0553213T3 (da) | Fremgangsmåde til fremstilling af (4R-cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxan- 4-acetat | |
| DK0594291T3 (da) | Fremgangsmåder til fremstilling af 13-etherderivater af milbemyciner og mellemprodukter dertil | |
| DK0446699T3 (da) | Inhibitorer af nitrogenoxid-biosyntese | |
| ES2082876T3 (es) | Derivados de dialcoximetilimidazolidina, su preparacion, insecticidas que los contienen como ingrediente efectivo y sus intermedios. | |
| DK0423697T3 (da) | Lipidemulsion indeholdende en prostaglandinanalog | |
| ES555426A0 (es) | Un procedimiento para la preparacion de derivados de aciluretano polimerizables. | |
| DE3679538D1 (de) | Verwendung einer esterverbindung als temporaeres mikrobizid. | |
| ES541544A0 (es) | Un metodo de preparar bestatinas | |
| ES479444A1 (es) | Un procedimiento para preparar derivados de pirrolidincarbo-xaldehido y piperidicarboxaldehido. | |
| FI820240L (fi) | Nytt framstaellningsfoerfarande foer 17alfa-hydroxi-17beta-hydroxiacetylsteroider och pao motsvarande saett erhaollna mellanprodukter | |
| DK328581A (da) | Fremgangsmaade til fremstilling af 6-aminopenicillansyre-1,1-dioxid | |
| DK36689D0 (da) | Fremgangsmaade til fremstilling af et 16-methoxy-16-methyl-prostaglandin e1-derivat, samt ved fremgangsmaaden anvendelige mellemprodukter | |
| JPS53101308A (en) | Derivative of 5,6-dihydro-2h-pyran and its preparation | |
| DK0496362T3 (da) | Fremgangsmåde til fremstilling af malonsyrederivater | |
| DK271785D0 (da) | Fremgangsmaade til fremstilling af substituerede derivater af 1,3-dioxan | |
| ES2038672T3 (es) | Antagonistas h1 purinicos de la histamina, su preparacion y composiciones farmaceuticas que los contienen. | |
| ES476073A1 (es) | Procedimiento para la obtencion de derivados tio-alquil-ni- trogenados de imidazol. | |
| DK284080A (da) | Fremgangsmaade til fremstilling af clavulansyrederivater |