DK0492500T3 - Protektive Plasmodium falciparum-hybridproteiner, der indeholder delsekvenser af malaria-antigenerne HRPII og SERP - Google Patents

Protektive Plasmodium falciparum-hybridproteiner, der indeholder delsekvenser af malaria-antigenerne HRPII og SERP

Info

Publication number: DK0492500T3
Authority: DK; Denmark
Prior art keywords: hrpii; serp; protective; hybrid proteins; amino acids
Prior art date: 1990-12-24

Application number

DK91121936.8T

Other languages

English (en)

Inventor

Hans Dr Kuepper

Bernhard Dr Knapp

Erika Dr Hundt

Burkhard Dr Enders

Original Assignee

Behringwerke Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-12-24

Filing date

1991-12-20

Publication date

1996-08-12

1991-12-20 Application filed by Behringwerke Ag filed Critical Behringwerke Ag

1996-08-12 Application granted granted Critical

1996-08-12 Publication of DK0492500T3 publication Critical patent/DK0492500T3/da

Links

108090000623 proteins and genes Proteins 0.000 title abstract 5
102000004169 proteins and genes Human genes 0.000 title abstract 5
QEVHRUUCFGRFIF-UHFFFAOYSA-N 6,18-dimethoxy-17-[oxo-(3,4,5-trimethoxyphenyl)methoxy]-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid methyl ester Chemical compound C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 QEVHRUUCFGRFIF-UHFFFAOYSA-N 0.000 title abstract 3
101100533283 Dictyostelium discoideum serp gene Proteins 0.000 title abstract 3
239000000427 antigen Substances 0.000 title abstract 3
102000036639 antigens Human genes 0.000 title abstract 3
108091007433 antigens Proteins 0.000 title abstract 3
201000004792 malaria Diseases 0.000 title abstract 3
230000001681 protective effect Effects 0.000 title abstract 3
241000223960 Plasmodium falciparum Species 0.000 title abstract 2
150000001413 amino acids Chemical class 0.000 abstract 4
210000001744 T-lymphocyte Anatomy 0.000 abstract 2
101710203310 Apical membrane antigen 1 Proteins 0.000 abstract 1
241000282693 Cercopithecidae Species 0.000 abstract 1
210000004899 c-terminal region Anatomy 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
238000011081 inoculation Methods 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Tropical Medicine & Parasitology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK91121936.8T 1990-12-24 1991-12-20 Protektive Plasmodium falciparum-hybridproteiner, der indeholder delsekvenser af malaria-antigenerne HRPII og SERP DK0492500T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4041836A DE4041836A1 (de)	1990-12-24	1990-12-24	Protektive plasmodium falciparum hybridproteine, die teilsequenzen der malaria-antigene hrpii und serp enthalten, ihre herstellung und verwendung

Publications (1)

Publication Number	Publication Date
DK0492500T3 true DK0492500T3 (da)	1996-08-12

Family

ID=6421479

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91121936.8T DK0492500T3 (da)	1990-12-24	1991-12-20	Protektive Plasmodium falciparum-hybridproteiner, der indeholder delsekvenser af malaria-antigenerne HRPII og SERP

Country Status (13)

Country	Link
US (1)	US5395614A (da)
EP (1)	EP0492500B1 (da)
JP (1)	JPH06121688A (da)
KR (1)	KR920012116A (da)
AT (1)	ATE136586T1 (da)
AU (1)	AU660437B2 (da)
CA (1)	CA2057761A1 (da)
DE (2)	DE4041836A1 (da)
DK (1)	DK0492500T3 (da)
ES (1)	ES2085947T3 (da)
GR (1)	GR3019825T3 (da)
IE (1)	IE80429B1 (da)
PT (1)	PT99923B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5928902A (en) *	1992-02-27	1999-07-27	Smithkline Beecham Biologicals (S.A.)	Hybrid protein between CS from plasmodium and HBsAg
US6254869B1 (en) *	1996-03-27	2001-07-03	The Regents Of The University Of California	Cryptopain vaccines, antibodies, proteins, peptides, DNA and RNA for prophylaxis, treatment and diagnosis and for detection of cryptosporidium species
OA11520A (en) *	1997-10-20	2004-02-09	Genzyme Transgenics Corp	Novel modified MSP-1 nucleic acid sequences and methods for increasing mRNA levels and protein expression in cell systems.
WO2002059319A1 (en) *	2001-01-24	2002-08-01	The Research Foundation For Microbial Diseases Of Osaka University	Malaria plasmodium antigen polypeptide se36, method of purifying the same and vaccine and diagnostic with the use of the thus obtained antigen
AU2003216384A1 (en) *	2002-03-01	2003-09-16	Takara Bio, Inc.	Cold shock inducible expression and production of heterologous polypeptides
US8556843B2 (en) *	2008-02-02	2013-10-15	AccelDx	Blood purification method and apparatus for the treatment of malaria

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4859465A (en) *	1984-04-20	1989-08-22	The Regents Of The University Of California	Vaccine capable of eliciting multivalent antibodies
CA1302805C (en) *	1986-05-15	1992-06-09	Thomas Alan Taylor	Liquid film coating of iron-based metals
EP0254862A1 (en) *	1986-06-26	1988-02-03	BEHRINGWERKE Aktiengesellschaft	Vaccines against protozoan parasites
US5130416A (en) *	1986-08-13	1992-07-14	The United States Of America As Represented By The Department Of Health And Human Services	Recombinant DNA clone containing a genomic fragment of PfHRP-II gene from plasmodium falciparum
WO1988002757A1 (en) *	1986-10-17	1988-04-21	Saramane Pty. Ltd.;	Hybrid proteins or polypeptides
US4957738A (en) *	1987-01-14	1990-09-18	Patarroyo Manuel E	Protein copolymer malaria vaccine
DE3741057A1 (de) *	1987-03-18	1988-09-29	Behringwerke Ag	Klonierung von malaria-spezifischen dna-sequenzen:isolierung des gens fuer das 140 kd protein
DE3737238A1 (de) *	1987-11-03	1989-05-18	Behringwerke Ag	Rekombinantes histidinreiches protein (37 kd antigen) von plasmodium falciparum, seine herstellung und verwendung
DE3831351A1 (de) *	1987-12-30	1989-07-13	Behringwerke Ag	Malaria-spezifische dna-sequenzen, ihre expressionsprodukte und deren verwendung
WO1990001549A2 (en) *	1988-08-12	1990-02-22	Trustees Of Dartmouth College	Gene encoding protein antigens of plasmodium falciparum

1990
- 1990-12-24 DE DE4041836A patent/DE4041836A1/de not_active Withdrawn
1991
- 1991-12-20 CA CA002057761A patent/CA2057761A1/en not_active Abandoned
- 1991-12-20 DE DE59107665T patent/DE59107665D1/de not_active Expired - Fee Related
- 1991-12-20 ES ES91121936T patent/ES2085947T3/es not_active Expired - Lifetime
- 1991-12-20 DK DK91121936.8T patent/DK0492500T3/da active
- 1991-12-20 AT AT91121936T patent/ATE136586T1/de active
- 1991-12-20 AU AU89894/91A patent/AU660437B2/en not_active Ceased
- 1991-12-20 EP EP91121936A patent/EP0492500B1/de not_active Expired - Lifetime
- 1991-12-23 IE IE455191A patent/IE80429B1/en not_active IP Right Cessation
- 1991-12-23 KR KR1019910023919A patent/KR920012116A/ko not_active Application Discontinuation
- 1991-12-23 PT PT99923A patent/PT99923B/pt not_active IP Right Cessation
- 1991-12-24 JP JP3356233A patent/JPH06121688A/ja active Pending
1993
- 1993-11-16 US US08/152,922 patent/US5395614A/en not_active Expired - Fee Related
1996
- 1996-05-03 GR GR960401198T patent/GR3019825T3/el unknown

Also Published As

Publication number	Publication date
IE914551A1 (en)	1992-07-01
DE59107665D1 (de)	1996-05-15
AU660437B2 (en)	1995-06-29
PT99923A (pt)	1992-12-31
JPH06121688A (ja)	1994-05-06
EP0492500B1 (de)	1996-04-10
EP0492500A3 (en)	1993-02-10
DE4041836A1 (de)	1992-06-25
ATE136586T1 (de)	1996-04-15
PT99923B (pt)	1999-06-30
EP0492500A2 (de)	1992-07-01
ES2085947T3 (es)	1996-06-16
CA2057761A1 (en)	1992-06-25
IE80429B1 (en)	1998-07-01
AU8989491A (en)	1992-06-25
US5395614A (en)	1995-03-07
KR920012116A (ko)	1992-07-25
GR3019825T3 (en)	1996-08-31

Publication	Publication Date	Title
DK0725824T3 (da)	2003-08-11	Immunodominante humane T-celleepitoper af hepatitis C virus
ATE80310T1 (de)	1992-09-15	Antigenische proteine, dieselben enthaltende vakzine, schuetzende antikoerper dagegen fuer die verhuetung von durch eimeria tenella verursachte coccidiosis.
DK0492500T3 (da)	1996-08-12	Protektive Plasmodium falciparum-hybridproteiner, der indeholder delsekvenser af malaria-antigenerne HRPII og SERP
DE69101646D1 (de)	1994-05-19	Vakzine gegen Coccidiose.
ATA171686A (de)	1990-02-15	Verfahren zur herstellung von gegen pseudomonas aeruginosa infektionen wirksamen praeparationen
DE69127974D1 (de)	1997-11-20	Peptide und deren verwendung
KR920006503A (ko)	1992-04-27	살모넬라 백신 균주의 표면에 면역원성 말라리아 항원을 발현할수 있는 재조합 발현 벡터
ES2091159A1 (es)	1996-10-16	Antigeno recombinante, rsm14, procedente de schistosoma mansoni, su obtencion y utilizacion.
KR900701831A (ko)	1990-12-04	열대열 말라리아 원충의 분열소체 표면 항원의 대립형질 변이주
Knapp et al.	1995	Protective plasmodium falciparum hybrid proteins which contain part-sequences of the malaria antigens HRPII and SERP, the preparation and use thereof
GB2244273A (en)	1991-11-27	Allelic variants of plasmodium falciparum merozoite surface antigen.