DK0400583T3 - Imidazoquinoxalinoner,deres azaanaloger og fremgangsmåde til fremstilling deraf - Google Patents

Imidazoquinoxalinoner,deres azaanaloger og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0400583T3
DK0400583T3 DK90110191T DK90110191T DK0400583T3 DK 0400583 T3 DK0400583 T3 DK 0400583T3 DK 90110191 T DK90110191 T DK 90110191T DK 90110191 T DK90110191 T DK 90110191T DK 0400583 T3 DK0400583 T3 DK 0400583T3
Authority
DK
Denmark
Prior art keywords
imidazoquinoxalinones
preparation
methods
aza analogues
aza
Prior art date
Application number
DK90110191T
Other languages
English (en)
Inventor
David Daniel Davey
Original Assignee
Berlex Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berlex Lab filed Critical Berlex Lab
Application granted granted Critical
Publication of DK0400583T3 publication Critical patent/DK0400583T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK90110191T 1989-05-31 1990-05-29 Imidazoquinoxalinoner,deres azaanaloger og fremgangsmåde til fremstilling deraf DK0400583T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/359,182 US5055465A (en) 1989-05-31 1989-05-31 Imidazoquinoxalinones, their aza analogs and process for their preparation

Publications (1)

Publication Number Publication Date
DK0400583T3 true DK0400583T3 (da) 2000-03-13

Family

ID=23412679

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90110191T DK0400583T3 (da) 1989-05-31 1990-05-29 Imidazoquinoxalinoner,deres azaanaloger og fremgangsmåde til fremstilling deraf

Country Status (7)

Country Link
US (1) US5055465A (da)
EP (1) EP0400583B1 (da)
AT (1) ATE186728T1 (da)
DE (1) DE69033355T2 (da)
DK (1) DK0400583T3 (da)
ES (1) ES2138956T3 (da)
GR (1) GR3032611T3 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5854419A (en) * 1989-11-17 1998-12-29 Schering Aktiengesellschaft Tricyclic pteridinones and a process for their preparation
US5602252A (en) * 1989-11-17 1997-02-11 Berlex Laboratories, Inc. Tricyclic pteridinones and a process for their preparation
US5182386A (en) * 1991-08-27 1993-01-26 Neurogen Corporation Certain imidazoquinoxalinones; a new class of gaba brain receptor ligands
PT647137E (pt) * 1992-06-22 2008-11-24 Univ California Antagonistas dos receptores da glicina e a sua utilização
DE4228095A1 (de) * 1992-08-24 1994-03-03 Asta Medica Ag Neue 4,5-Dihydro-4-oxo-pyrrolo[1,2-a]chinoxaline und entsprechende Aza-analoga und Verfahren zu deren Herstellung
US5306819A (en) * 1992-08-27 1994-04-26 Neurogen Corporation Certain aryl a cycloalkyl fused imidazopyrazinols; and new class of GABA brain receptor ligands
DE4310523A1 (de) * 1993-03-31 1994-10-06 Basf Ag Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
EP0743855A1 (en) * 1994-01-03 1996-11-27 Acea Pharmaceuticals, Inc. 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/nmda receptor
EP0743945B1 (en) * 1994-02-11 2002-03-06 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
WO1996010572A1 (de) * 1994-09-30 1996-04-11 Basf Aktiengesellschaft Neue heterocyclische substituierte imidazolo-chinoxalinone, ihre herstellung und verwendung
US5801183A (en) * 1995-01-27 1998-09-01 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Aza and aza (N-oxy) analogs of glycine/NMDA receptor antagonists
DE19510965A1 (de) * 1995-03-24 1996-09-26 Asta Medica Ag Neue Pyrido/3,2-e/pyrazinone mit antiasthmatischer Wirksamkeit und Verfahren zu deren Herstellung
DE19611476A1 (de) * 1996-03-22 1997-09-25 Basf Ag Neue heterocyclische substituierte Imidazolo-chinoxalinone, ihre Herstellung und Verwendung
SK10322001A3 (sk) * 1999-01-20 2002-07-02 Arzneimittelwerk Dresden Gmbh Spôsob prípravy imidazo [1,5-a]pyrido[3,2-e]pyrazínov, farmaceutické prostriedky obsahujúce takéto zlúčeniny a spôsob výroby farmaceutického prostriedku
DE19961302A1 (de) * 1999-12-18 2001-06-21 Dresden Arzneimittel Verwendung von Imidazo(1,5-a)-pyrido(3,2-e)-pyrazinonen als duale Inhibitoren der Phosphodiesterase 5 und der Phosphodiesterase 3 zur Therapie der Herzinsuffizienz, von pulmonaler Hypertonie und Gefäßerkrankungen, die mit einer Minderdurchblutung einhergehen
KR20020015030A (ko) * 1999-03-22 2002-02-27 스티븐 비. 데이비스 ｃＧＭＰ 포스포디에스테라제의 접합된 피리도피리다진억제제
US6465465B1 (en) * 2000-03-14 2002-10-15 Arzneimittelwerk Dresden Gmbh Process for the treatment of erectile dysfunction and product therefor
DE10012373A1 (de) * 2000-03-14 2001-09-20 Dresden Arzneimittel Verwendung von Pyrido[3,2-e]-pyrazinonen als Inhibitoren der Phosphodiesterase 5 zur Therapie von erektiler Dysfunktion
EP1312363A1 (en) * 2001-09-28 2003-05-21 Pfizer Products Inc. Methods of treatment and kits comprising a growth hormone secretagogue
US7342884B2 (en) * 2002-03-13 2008-03-11 Harmonic, Inc. Method and apparatus for one directional communications in bidirectional communications channel
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
TW200817400A (en) * 2006-05-30 2008-04-16 Elbion Ag Pyrido [3,2-e] pyrazines, their use as inhibitors of phosphodiesterase 10, and processes for preparing them
US8299080B2 (en) 2006-12-13 2012-10-30 Aska Pharmaceutical Co., Ltd. Substituted imidazo[1,5-A] quinoxalines as a PDE9 inhibitor
JP2011504892A (ja) * 2007-11-30 2011-02-17 ビオティエ セラピーズ ゲゼルシャフト ミット ベシュレンクテル ハフツング ホスホジエステラーゼ１０の阻害剤としてのアリール及びヘテロアリール縮合イミダゾ（１，５−ａ）ピラジン
WO2009070583A1 (en) * 2007-11-30 2009-06-04 Wyeth Pyrido[3,2-e]pyrazines, process for preparing the same, and their use as inhibitors of phosphodiesterase 10
KR20100110804A (ko) * 2007-11-30 2010-10-13 와이어쓰 엘엘씨 포스포디에스테라제 10의 저해물질로서의 아릴 및 헤테로아릴 융합된 이미다조[1,5-ａ]피라진
CA2750106A1 (en) 2009-01-23 2010-07-29 Takeda Pharmaceutical Company Limited Poly (adp-ribose) polymerase (parp) inhibitors
US8541417B2 (en) 2009-07-30 2013-09-24 Takeda Pharmaceutical Company Limited Poly (ADP-ribose) polymerase (PARP) inhibitors
WO2011081915A2 (en) * 2009-12-15 2011-07-07 Cebix Inc. Methods for treating erectile dysfunction in patients with insulin-dependent diabetes
JP5822080B2 (ja) 2010-09-07 2015-11-24 アステラス製薬株式会社 キノキサリン化合物

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138564A (en) * 1977-08-03 1979-02-06 American Home Products Corporation Tetrahydro[1H]pyrazino[1,2-a]azaquinoxalin-5(6H)-ones and derivatives thereof
IL59104A (en) * 1979-02-09 1984-02-29 Roussel Uclaf Heterotricyclic derivatives,process for their preparation and pharmaceutical compositions incorporating them
US4333394A (en) * 1979-12-31 1982-06-08 Brown Stanford M Method for handling and baling metallic scrap material
US4440929A (en) * 1981-07-16 1984-04-03 Usv Pharmaceutical Corporation Imidazoquinoxaline compounds
US4761414A (en) * 1986-08-19 1988-08-02 G. D. Searle & Co. Substituted 1H-pyrimido[1,2-a-]-pyrido[3,4-e]pyrazine 6 oxides

Also Published As

Publication number Publication date
EP0400583A1 (en) 1990-12-05
DE69033355D1 (de) 1999-12-23
US5055465A (en) 1991-10-08
GR3032611T3 (en) 2000-05-31
EP0400583B1 (en) 1999-11-17
ATE186728T1 (de) 1999-12-15
ES2138956T3 (es) 2000-02-01
DE69033355T2 (de) 2000-05-11

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