DE946221T1 - Bekämpfung von infektionen in medizinischen freisetzungssystemen - Google Patents

Bekämpfung von infektionen in medizinischen freisetzungssystemen

Info

Publication number
DE946221T1
DE946221T1 DE0946221T DE97950310T DE946221T1 DE 946221 T1 DE946221 T1 DE 946221T1 DE 0946221 T DE0946221 T DE 0946221T DE 97950310 T DE97950310 T DE 97950310T DE 946221 T1 DE946221 T1 DE 946221T1
Authority
DE
Germany
Prior art keywords
taurolidine
taurultam
sepsis
release systems
delivery system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0946221T
Other languages
English (en)
Inventor
Joachim Lehner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ed Geistlich Soehne AG fuer Chemische Industrie
Original Assignee
Ed Geistlich Soehne AG fuer Chemische Industrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10804970&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE946221(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ed Geistlich Soehne AG fuer Chemische Industrie filed Critical Ed Geistlich Soehne AG fuer Chemische Industrie
Publication of DE946221T1 publication Critical patent/DE946221T1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Materials For Medical Uses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Claims (5)

• &igr; · ·: :.···■·. a DE/EP0 94622U1 R/10007 Patentansprüche:
1. Verwendung einer Taurolidin- oder Taurultam-Lösung zum vorübergehenden Verschließen oder Spülen zur Vermeidung oder Linderung von Infektionen und Sepsis in Flüssigkeitsabgabesystemen.
2. Verwendung nach Anspruch 1, wobei das Abgabesystem die Verwendung eines Katheters beinhaltet.
3. Verwendung nach Anspruch 1 oder Anspruch 2, wobei das Abgabesystem ein subkutan implantiertes Abgabesystem oder Zugangssystem ist.
4. Verwendung nach einem der Ansprüche 1 bis 3, wobei die Lösung 0,5 bis Gew.-% Taurolidin oder 1 bis 7,5 Gew.-% Taurultam enthält.
5. Verfahren zur Vermeidung oder Linderung von Infektionen und Sepsis in einem Flüssigkeitsabgabesystem, wobei man das System mit einer Taurolidin- oder Taurultam-Lösung füllt, ausspült oder vorübergehend verschließt.
DE0946221T 1996-12-23 1997-12-23 Bekämpfung von infektionen in medizinischen freisetzungssystemen Pending DE946221T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9626795.0A GB9626795D0 (en) 1996-12-23 1996-12-23 Combating infection in delivery systems
PCT/GB1997/003524 WO1998028027A1 (en) 1996-12-23 1997-12-23 Combatting infection in delivery systems

Publications (1)

Publication Number Publication Date
DE946221T1 true DE946221T1 (de) 2002-11-14

Family

ID=10804970

Family Applications (2)

Application Number Title Priority Date Filing Date
DE0946221T Pending DE946221T1 (de) 1996-12-23 1997-12-23 Bekämpfung von infektionen in medizinischen freisetzungssystemen
DE69736605T Expired - Lifetime DE69736605T2 (de) 1996-12-23 1997-12-23 Verwendung von taurolidin oder taurultam zur behandlung und prävention von infektionen in medizinischen freisetzungssystemen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69736605T Expired - Lifetime DE69736605T2 (de) 1996-12-23 1997-12-23 Verwendung von taurolidin oder taurultam zur behandlung und prävention von infektionen in medizinischen freisetzungssystemen

Country Status (9)

Country Link
US (1) US6258797B1 (de)
EP (1) EP0946221B1 (de)
JP (1) JP4373500B2 (de)
AT (1) ATE337786T1 (de)
CA (1) CA2275763C (de)
DE (2) DE946221T1 (de)
ES (1) ES2177483T3 (de)
GB (1) GB9626795D0 (de)
WO (1) WO1998028027A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9626795D0 (en) 1996-12-23 1997-02-12 Geistlich Soehne Ag Combating infection in delivery systems
US8304390B2 (en) * 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
US20050124608A1 (en) * 2001-04-03 2005-06-09 Redmond H. P. Treatment of cancers
US7132413B1 (en) 1997-07-31 2006-11-07 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Anticoagulant/sterilizing compositions and methods
US20070275955A1 (en) * 1997-07-31 2007-11-29 Ed. Geistlich Soehne Ag Method of treating tumors
US6166007A (en) † 1998-07-02 2000-12-26 Sodemann; Klaus Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof
CA2302720C (en) * 1999-03-29 2009-07-14 Ed Geistlich Sohne Ag Fur Chemische Industrie Anticoagulant/sterilizing compositions and methods
US7345039B2 (en) 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
US8030301B2 (en) 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US7892530B2 (en) 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US6641571B2 (en) * 2000-01-05 2003-11-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery
JP5143982B2 (ja) * 2001-05-08 2013-02-13 エヌディー パートナーズ，リミティド ライアビリティー カンパニー 殺生物剤ロック
US20040092890A1 (en) * 2001-05-10 2004-05-13 Ash Stephen R. Catheter lock solution including a photo-oxidant
US20050215978A1 (en) * 2001-05-25 2005-09-29 Ash Stephen R Method of enhancing catheter patency using a citrate salt catheter lock solution
IL162083A0 (en) * 2001-11-26 2005-11-20 Genentech Inc Catheter composition and uses thereof
US6803363B2 (en) * 2002-05-31 2004-10-12 Nd Partners, Llc Peritoneal dialysis solution with taurolidine
DE60311958T2 (de) * 2003-02-03 2007-11-08 Polaschegg, Hans-Dietrich, Dr. Zusammensetzung zur Prävention von Infektionen durch subkutane Prothesen
US8394397B2 (en) * 2003-03-28 2013-03-12 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Adhesive antineoplastic compositions
DE10331557B3 (de) * 2003-07-11 2005-02-17 Herdeis, Claus, Prof. Dr. Verwendung von Taurolidin und Taurultam in Zubereitungen zur Behandlung, Reinigung, Aufbewahrung und zum Conditioning von Kontaktlinsen
US7696182B2 (en) 2004-11-02 2010-04-13 Nd Partners, Llc Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin
US7749529B2 (en) * 2005-02-08 2010-07-06 Ash Access Technology, Inc. Catheter lock solution comprising citrate and a paraben
EP1882476B1 (de) 2006-07-25 2008-11-19 HERDEIS, Claus Herstellung von antimikrobiellen Formulierungen unter Verwendung von 7-Oxa-2-thia 1,5-diazabicyclo[3.3.1]nonan-2,2-dion
CA2668347C (en) 2006-11-07 2017-06-20 Genentech, Inc. Tissue plasminogen activator variant uses
US8389583B2 (en) 2008-05-23 2013-03-05 Zurex Pharma, Inc. Antimicrobial compositions and methods of use
US9248093B2 (en) 2009-06-11 2016-02-02 Becton, Dickinson And Company Catheter locking solution having antimicrobial and anticoagulation properties
JP5379192B2 (ja) * 2011-07-01 2013-12-25 エヌディー パートナーズ，リミティド ライアビリティー カンパニー 殺生物剤ロック
US11738120B1 (en) 2022-04-14 2023-08-29 Cormedix Inc. Synthesis of taurolidine, purity profiles and polymorphs

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1124285A (en) 1964-10-06 1968-08-21 Geistlich Soehne Ag Novel perhydro-1,2,4-thiadiazine dioxides-(1,1), their preparation and compositionscontaining them
CA1190855A (en) 1980-09-03 1985-07-23 Rolf W. Pfirrmann Treatment of osteitis
DE3506288A1 (de) 1984-09-06 1986-03-13 Johannes 7900 Ulm Reinmüller Vorrichtung zum einlegen in wunden und wundhoehlen
DE3533612A1 (de) 1985-09-20 1987-04-02 Johannes Reinmueller Neuartige verwendung von taurolin
US5210083A (en) 1986-07-17 1993-05-11 Ed. Geistlich Sohne A.G. Fur Chemische Industrie Pharmaceutical compositions
US5167960A (en) 1988-08-03 1992-12-01 New England Deaconess Hospital Corporation Hirudin-coated biocompatible substance
US5352204A (en) 1990-03-01 1994-10-04 Ensminger William D Implantable access devices
US5263930A (en) 1990-03-01 1993-11-23 William D. Ensminger Implantable access devices
DE59010227D1 (de) 1990-11-02 1996-04-25 Marion Dipl Phys Giebel Infektvorbeugende katheteranordnung
DE19606897C2 (de) 1996-02-13 2002-08-29 Geistlich Soehne Ag Mittel zur Verhinderung der Tumorzellverschleppung und der Entstehung von Trokarmetastasen in der offenen und laparoskopischen Chirurgie maligner Tumoren
US6146363A (en) 1996-10-24 2000-11-14 Giebel; Marion Anti-infection catheter
GB9626795D0 (en) 1996-12-23 1997-02-12 Geistlich Soehne Ag Combating infection in delivery systems
GB9716219D0 (en) 1997-07-31 1997-10-08 Geistlich Soehne Ag Prevention of metastases
US6166007A (en) 1998-07-02 2000-12-26 Sodemann; Klaus Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof
US6174537B1 (en) 1998-09-25 2001-01-16 Becton, Dickinson And Company Catheter flush solution and method for its use

Also Published As

Publication number Publication date
ES2177483T1 (es) 2002-12-16
ES2177483T3 (es) 2007-03-16
CA2275763C (en) 2006-11-21
JP4373500B2 (ja) 2009-11-25
EP0946221B1 (de) 2006-08-30
DE69736605D1 (de) 2006-10-12
US6258797B1 (en) 2001-07-10
DE69736605T2 (de) 2007-09-20
WO1998028027A1 (en) 1998-07-02
ATE337786T1 (de) 2006-09-15
JP2001507019A (ja) 2001-05-29
EP0946221A1 (de) 1999-10-06
GB9626795D0 (en) 1997-02-12
CA2275763A1 (en) 1998-07-02

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