DE9410766U1 - Pick-me-up spray - Google Patents
Pick-me-up sprayInfo
- Publication number
- DE9410766U1 DE9410766U1 DE9410766U DE9410766U DE9410766U1 DE 9410766 U1 DE9410766 U1 DE 9410766U1 DE 9410766 U DE9410766 U DE 9410766U DE 9410766 U DE9410766 U DE 9410766U DE 9410766 U1 DE9410766 U1 DE 9410766U1
- Authority
- DE
- Germany
- Prior art keywords
- spray
- pick
- sugar
- flavoring
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007921 spray Substances 0.000 title claims description 10
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 239000004480 active ingredient Substances 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- 235000021092 sugar substitutes Nutrition 0.000 claims description 4
- 239000003765 sweetening agent Substances 0.000 claims description 4
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims description 3
- 229960001948 caffeine Drugs 0.000 claims description 3
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims description 3
- 239000003380 propellant Substances 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 239000000796 flavoring agent Substances 0.000 claims 1
- 208000016255 tiredness Diseases 0.000 description 4
- 230000003867 tiredness Effects 0.000 description 4
- 239000000021 stimulant Substances 0.000 description 3
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 2
- 230000000845 anti-microbial effect Effects 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- OOBHFESNSZDWIU-GXSJLCMTSA-N (2s,3s)-3-methyl-2-phenylmorpholine Chemical compound C[C@@H]1NCCO[C@H]1C1=CC=CC=C1 OOBHFESNSZDWIU-GXSJLCMTSA-N 0.000 description 1
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 244000246386 Mentha pulegium Species 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229940025084 amphetamine Drugs 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 150000004982 aromatic amines Chemical class 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 229960002179 ephedrine Drugs 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229960001252 methamphetamine Drugs 0.000 description 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 229960003209 phenmetrazine Drugs 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 229940001470 psychoactive drug Drugs 0.000 description 1
- 239000004089 psychotropic agent Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Detergent Compositions (AREA)
Description
7147/lII/hn7147/lII/hn
Die Erfindung betrifft einen Spray, der einen Wirkstoff enthält, der beim Einsprühen in die Mundhöhle über die Mundschleimhäute aufgenommen und schnell resorbiert wird, so daß ein plötzlich auftretendes Müdigkeitssymptom schnell und wirksam unterdrückt werden kann.The invention relates to a spray containing an active ingredient which, when sprayed into the oral cavity, is absorbed through the oral mucous membranes and is rapidly reabsorbed, so that a suddenly occurring symptom of fatigue can be quickly and effectively suppressed.
Mittel zum Vertreiben von auftretender Müdigkeit und gegen Schlafbedürfnis sind unter der Bezeichnung Weckamine (Psychopharmaka) bekannt, deren Vertreter chemisch mit den aromatischen Aminen Adrenalin und Ephedrin verwandt sind, wie beispielsweise Amphetamin, Methamphetamin, Phenmetrazin und ähnliche. Diese Weckamine wirken als Kreislaufmittel und regen die Herztätigkeit an, wodurch die Müdigkeit verscheucht und das Schlafbedürfnis unterdrückt wird. Obwohl die bekannten Weckamine eine Steigerung der Leistungsfähigkeit für einen kurzen Zeitraum ermöglichen, ist deren Einsatz wegen suchterzeugender Nebenwirkungen nicht problemlos.Means for fighting tiredness and the need for sleep are known as stimulants (psychotropic drugs), whose representatives are chemically related to the aromatic amines adrenaline and ephedrine, such as amphetamine, methamphetamine, phenmetrazine and similar. These stimulants act as circulatory agents and stimulate the heart, thereby banishing tiredness and suppressing the need for sleep. Although the known stimulants enable an increase in performance for a short period of time, their use is not without problems due to addictive side effects.
Der Erfindung liegt daher die Aufgabe zugrunde, ein Mittel zur Verfügung zu stellen, das schnell und wirksam auftretende Müdigkeit vertreibt und das Schlafbedürfnis unterdrückt und frei von beispielsweise suchterzeugenden Nebenwirkungen ist.The invention is therefore based on the object of providing a means that quickly and effectively dispels tiredness and suppresses the need for sleep and is free from, for example, addictive side effects.
Diese Aufgabe wird durch den im Anspruch beschriebenen Muntermacher-Spray gelöst.This task is solved by the pick-me-up spray described in the claim.
Gegenstand der Erfindung ist daher ein Muntermacher-Spray, welcher neben gegebenenfalls verwendetem Treibgas eine Zusammensetzung umfaßt, bestehend aus 3 bis 10 Gew.-% Coffein, 0,1 bis 5 Gew.-% natürlichen oder naturidentischen Aromastoffen, 1 bis 8 Gew.-% Zuckeraustauschstoffen und 0,1 bis 0,5 Gew.-% Konservierungsstoffen sowie der Restmenge Wasser.The subject of the invention is therefore a pick-me-up spray which, in addition to any propellant gas used, comprises a composition consisting of 3 to 10% by weight of caffeine, 0.1 to 5% by weight of natural or nature-identical flavorings, 1 to 8% by weight of sugar substitutes and 0.1 to 0.5% by weight of preservatives, as well as the remainder being water.
Als Aromastoffe können natürliche oder naturidentische bekannte Aromastoffe, wie Fruchtaroma, Pfefferminzaroma, Schokoladenaroma oder ähnliche zusammen mit einem geringen Zusatz eines antimikrobiellen Aromastoffes als Konservierungsstoff, wie z.B. Conarom H3, verwendet werden.Natural or nature-identical known flavorings such as fruit flavoring, peppermint flavoring, chocolate flavoring or similar can be used as flavorings together with a small addition of an antimicrobial flavoring as a preservative, such as Conarom H3.
Als weitere Konservierungsstoffe sind Vitamin C oder Benzoesäure und ähnliche verwendbar.Other preservatives that can be used include vitamin C or benzoic acid and similar.
Als Zuckeraustauschstoffe können die im Handel erhältlichen verwendet werden, es kann jedoch auch zur Geschmacksverbesserung natürlicher Zucker eingesetzt werden oder beides.Commercially available sugar substitutes can be used, but natural sugar can also be used to improve the taste, or both.
Die oben beschriebene Zusammensetzung wird gegebenenfalls zusammen mit einem Flüssigtreibgas in eine Spraydose eingefüllt oder in einen Pump-Spray mit Fingerzerstäuber.The composition described above is filled into a spray can, together with a liquid propellant if necessary, or into a pump spray with a finger atomizer.
Im folgenden wird ein Ausführungsbeispiel für die Zusammensetzung für einen Muntermacher-Spray angegeben:The following is an example of the composition for a pick-me-up spray:
Conarom H3 (antimikrobieller Aromastoff) 0,5 Gew.-%Conarom H3 (antimicrobial flavouring) 0.5 wt.%
Coffein 5 Gew.%Caffeine 5 wt.%
Aromastoff 3,0 Gew.-%Flavoring 3.0% w/w
Zuckeraustauschstoff 2,0 Gew.-%Sugar substitute 2.0 wt.%
Restmenge destilliertes Wasser auf 100 Gew.-%Remaining amount of distilled water to 100 wt.%
Der erfindungsgemäße Muntermacher-Spray besitzt den Vorteil, daß bei oraler Aufnahme durch Versprühen der Wirkstoffzusammensetzung auf die Mundschleimhäute eine rasche Resorption des Wirk-The pick-me-up spray according to the invention has the advantage that when taken orally by spraying the active ingredient composition onto the oral mucosa, rapid absorption of the active ingredient
Stoffs wegen der gleichmäßigen flächigen Verteilung eintritt. Durch die Zerstäubung in aerosolähnliche Tröpfchen erhält die Lösung eine große Oberfläche => schnelle Resorption, so daß bei sich einstellender Müdigkeit, beispielsweise beim Lenken eines Fahrzeugs, rasch und wirksam das Schlafbedürfnis unterdrückt werden kann.substance due to the even distribution over the surface. By atomizing it into aerosol-like droplets, the solution has a large surface area => rapid absorption, so that when tiredness sets in, for example when driving a vehicle, the need for sleep can be suppressed quickly and effectively.
Claims (1)
bestehend aus 3 bis 10 Gew.-% Coffein, 0,1 bis 5 Gew.-% natürlichen oder naturidentischen Aromastoffen, 1 bis 8 Gew.-% Zucker oder Zuckeraustauschstoffen und 0,1 bis 0,5 Gew.-% Konservierungsstoffen sowie der Restmenge Wasser besteht, sowie gegebenenfalls Treibgas.Stimulant spray containing an active ingredient composition,
consisting of 3 to 10 wt.% caffeine, 0.1 to 5 wt.% natural or nature-identical flavourings, 1 to 8 wt.% sugar or sugar substitutes and 0.1 to 0.5 wt.% preservatives and the balance being water, and optionally propellant gas.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE9410766U DE9410766U1 (en) | 1994-07-05 | 1994-07-05 | Pick-me-up spray |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE9410766U DE9410766U1 (en) | 1994-07-05 | 1994-07-05 | Pick-me-up spray |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE9410766U1 true DE9410766U1 (en) | 1994-08-18 |
Family
ID=6910669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE9410766U Expired - Lifetime DE9410766U1 (en) | 1994-07-05 | 1994-07-05 | Pick-me-up spray |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE9410766U1 (en) |
-
1994
- 1994-07-05 DE DE9410766U patent/DE9410766U1/en not_active Expired - Lifetime
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