DE810027C - Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols - Google Patents
Process for the production of a novel Abkoemmlings des ‡ -PhenylaethylalkoholsInfo
- Publication number
- DE810027C DE810027C DEP19118D DEP0019118D DE810027C DE 810027 C DE810027 C DE 810027C DE P19118 D DEP19118 D DE P19118D DE P0019118 D DEP0019118 D DE P0019118D DE 810027 C DE810027 C DE 810027C
- Authority
- DE
- Germany
- Prior art keywords
- production
- novel
- phenylaethylalkohols
- abkoemmlings
- des
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
Verfahren zur Herstellung eines neuartigen Abkömmlings des a-Phenyläthylalkohols Es ist bekannt, daß man durch Umsetzung von a-Phenyläthylalkohol mit Bernsteinsäureanhydrid den sauren Bernsteinsäureester erhält, doch ist dessen Aufarbeitung und Abtrennung von mitentstandenen Nebenprcdukten umständlich und insbesondere die Isolierung und Reind irstellung seiner in Wasser leicht löslichen und schlecht kristallisierenden Alkali- und Erdalkalisalze mit Schwierigkeiten verbunden.Process for the preparation of a novel derivative of a-phenylethyl alcohol It it is known that by reacting α-phenylethyl alcohol with succinic anhydride the acid succinic acid ester is obtained, but its work-up and separation is of incidental byproducts cumbersome and especially the isolation and Purification of its easily soluble in water and poorly crystallizing Alkali and alkaline earth salts associated with difficulties.
Es wurde nun gefunden, daß man aus den wäßrigen Lösungen der Salze eine gut kristallisierende Doppelverbindung abscheiden kann, wenn man die Salzlösungen mit überschüssigem Calciumchlorid versetzt. It has now been found that the aqueous solutions of the salts a double compound that crystallizes well can be deposited if one uses the salt solutions mixed with excess calcium chloride.
Auf Grund ihrer Löslichkeitseigenschaften kann diese Doppelverbindung leicht von Begleitstoffen abgetrennt und in reiner Form in sehr guter Ausbeute erhalten werden.Due to their solubility properties, this double compound can easily separated from accompanying substances and obtained in pure form in very good yield will.
Das neue Calciumchloriddoppe lsalz besitzt wertvolle therapeutische Eigenschaften und kann als solches oder als Zwischenprodukt zur Herstellung von Heilmitteln verwendet werden. The new calcium chloride double salt has valuable therapeutic properties Properties and can be used as such or as an intermediate in the manufacture of Remedies are used.
Beispiel 6i g a-Phenyläthylalkohol werden mit 50 g Bernsteinsäureanhydrid 21/2 Stunden auf I40° erhitzt und die entstandene Estersäure nach Aufnehmen mit Benzol und Abfiltrieren von geringen Mengen Bernsteinsäure mit der berechneten Menge verdünnter Natronlauge in Lösung gebracht. Die neutrale, wäßrige Lösung des Natriumsalzes wird mit überschüssiger wäßriger Calciumchloridlösung versetzt. Hierbei fällt das Calciumchloriddoppelsalz als weißer kristalliner Niederschlag aus, der abgesaugt und nach dem Nachwaschen mit Wasser zunächst an der Luft und dann bei 50 bis 70" getrocknet wird. Example 6i g of a-phenylethyl alcohol are mixed with 50 g of succinic anhydride Heated 21/2 hours to 140 ° and the ester acid formed after absorption with Benzene and filter off small amounts of succinic acid with the calculated amount diluted sodium hydroxide solution brought into solution. The neutral, aqueous solution of the sodium salt is mixed with excess aqueous calcium chloride solution. This is where it falls Calcium chloride double salt as a white crystalline precipitate, which is sucked off and after washing with water first in the air and then at 50 to 70 " is dried.
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP19118D DE810027C (en) | 1948-10-22 | 1948-10-22 | Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP19118D DE810027C (en) | 1948-10-22 | 1948-10-22 | Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols |
Publications (1)
Publication Number | Publication Date |
---|---|
DE810027C true DE810027C (en) | 1951-08-06 |
Family
ID=7367328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DEP19118D Expired DE810027C (en) | 1948-10-22 | 1948-10-22 | Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE810027C (en) |
-
1948
- 1948-10-22 DE DEP19118D patent/DE810027C/en not_active Expired
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE810027C (en) | Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols | |
AT140867B (en) | Process for the preparation of dihydroresorcinol. | |
AT318813B (en) | PROCESS FOR PREPARING NEW ACYLOXY ALKYLESTERS OF 6- (ALPHA-AMINOPHENYLACETAMIDO) PENICILLANIC ACID | |
DE927269C (en) | Process for the preparation of new derivatives of 2-mercapto-naphthimidazole | |
DEP0019118DA (en) | Process for the production of a novel derivative of alpha; -phenylethyl alcohol. | |
DE734957C (en) | Process for the production of p-aminobenzenesulfonamide pellets | |
AT147483B (en) | Process for the preparation of compounds of methyl N-methyltetrahydronicotinate. | |
DE846398C (en) | Process for the production of organic cerium compounds | |
DE450022C (en) | Process for the preparation of allylarsic acid | |
DE938249C (en) | Process for the preparation of dihydrocodeine hydrorhodanide | |
DE944953C (en) | Process for the preparation of a therapeutic agent consisting of the calcium salt of Ca-ethylene diamine tetraacetic acid | |
DE865453C (en) | Process for the preparation of non-hygroscopic choline salts | |
DE720937C (en) | Process for the production of therapeutically valuable gold compounds from keratin breakdown products | |
DE1593317B2 (en) | METHOD OF MANUFACTURING AN ISMUTH ALUMINUM DOUBLE PECTATE | |
AT267750B (en) | Process for the production of a new penicillin | |
AT340380B (en) | PROCESS FOR THE MANUFACTURING OF PURE SODIUM (DI-N-PROPYL) ACETATE | |
AT274248B (en) | Process for the preparation of new derivatives of bufadienolide glycosides | |
DE469554C (en) | Process for the preparation of a bismuth alkaline tartrate | |
CH263037A (en) | Process for the preparation of a new derivative of 2-oxy-5-aminobenzoic acid. | |
CH121259A (en) | Process for the preparation of an acyl compound of amino-3-chloro-4-oxybenzene-1-arsic acid. | |
CH293814A (en) | Process for the preparation of a salt of an amino ester of penicillin. | |
DE1018052B (en) | Process for the preparation of antimony complex compounds of ª ‡, ª ‡ '-Dimercaptosuccinic acid | |
CH265118A (en) | Method for producing a local anesthetic. | |
CH194876A (en) | Process for the preparation of 2 (3 ', 5'-Diiodo-2'-B-oxethyl-4'-oxypheny) - 6-iodoquinoline-4-carboxylic acid. | |
CH119982A (en) | Procedure for displaying 5. 7-diiodisatin. |