DE810027C - Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols - Google Patents

Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols

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Publication number
DE810027C
DE810027C DEP19118D DEP0019118D DE810027C DE 810027 C DE810027 C DE 810027C DE P19118 D DEP19118 D DE P19118D DE P0019118 D DEP0019118 D DE P0019118D DE 810027 C DE810027 C DE 810027C
Authority
DE
Germany
Prior art keywords
production
novel
phenylaethylalkohols
abkoemmlings
des
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEP19118D
Other languages
German (de)
Inventor
Friedrich Dr Boedecker
Albrecht Dr Heymons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Honeywell Riedel de Haen AG
Original Assignee
Riedel de Haen AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riedel de Haen AG filed Critical Riedel de Haen AG
Priority to DEP19118D priority Critical patent/DE810027C/en
Application granted granted Critical
Publication of DE810027C publication Critical patent/DE810027C/en
Expired legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

Verfahren zur Herstellung eines neuartigen Abkömmlings des a-Phenyläthylalkohols Es ist bekannt, daß man durch Umsetzung von a-Phenyläthylalkohol mit Bernsteinsäureanhydrid den sauren Bernsteinsäureester erhält, doch ist dessen Aufarbeitung und Abtrennung von mitentstandenen Nebenprcdukten umständlich und insbesondere die Isolierung und Reind irstellung seiner in Wasser leicht löslichen und schlecht kristallisierenden Alkali- und Erdalkalisalze mit Schwierigkeiten verbunden.Process for the preparation of a novel derivative of a-phenylethyl alcohol It it is known that by reacting α-phenylethyl alcohol with succinic anhydride the acid succinic acid ester is obtained, but its work-up and separation is of incidental byproducts cumbersome and especially the isolation and Purification of its easily soluble in water and poorly crystallizing Alkali and alkaline earth salts associated with difficulties.

Es wurde nun gefunden, daß man aus den wäßrigen Lösungen der Salze eine gut kristallisierende Doppelverbindung abscheiden kann, wenn man die Salzlösungen mit überschüssigem Calciumchlorid versetzt. It has now been found that the aqueous solutions of the salts a double compound that crystallizes well can be deposited if one uses the salt solutions mixed with excess calcium chloride.

Auf Grund ihrer Löslichkeitseigenschaften kann diese Doppelverbindung leicht von Begleitstoffen abgetrennt und in reiner Form in sehr guter Ausbeute erhalten werden.Due to their solubility properties, this double compound can easily separated from accompanying substances and obtained in pure form in very good yield will.

Das neue Calciumchloriddoppe lsalz besitzt wertvolle therapeutische Eigenschaften und kann als solches oder als Zwischenprodukt zur Herstellung von Heilmitteln verwendet werden. The new calcium chloride double salt has valuable therapeutic properties Properties and can be used as such or as an intermediate in the manufacture of Remedies are used.

Beispiel 6i g a-Phenyläthylalkohol werden mit 50 g Bernsteinsäureanhydrid 21/2 Stunden auf I40° erhitzt und die entstandene Estersäure nach Aufnehmen mit Benzol und Abfiltrieren von geringen Mengen Bernsteinsäure mit der berechneten Menge verdünnter Natronlauge in Lösung gebracht. Die neutrale, wäßrige Lösung des Natriumsalzes wird mit überschüssiger wäßriger Calciumchloridlösung versetzt. Hierbei fällt das Calciumchloriddoppelsalz als weißer kristalliner Niederschlag aus, der abgesaugt und nach dem Nachwaschen mit Wasser zunächst an der Luft und dann bei 50 bis 70" getrocknet wird. Example 6i g of a-phenylethyl alcohol are mixed with 50 g of succinic anhydride Heated 21/2 hours to 140 ° and the ester acid formed after absorption with Benzene and filter off small amounts of succinic acid with the calculated amount diluted sodium hydroxide solution brought into solution. The neutral, aqueous solution of the sodium salt is mixed with excess aqueous calcium chloride solution. This is where it falls Calcium chloride double salt as a white crystalline precipitate, which is sucked off and after washing with water first in the air and then at 50 to 70 " is dried.

Claims (1)

PATENTANSPRUCH Verfahren zur Herstellung eines neuartigen Abkömmlings des a-Phenyläthylalkohols, dadurch gekennzeichnet, daß man, nach an sich bekannten Methoden gewonnene, wäßrige Lösungen von Salzen des sauren Bernsteinsäureesters des a-Phenyläthylalkohols mit überschüssigem Calciumchlorid versetzt. PATENT CLAIM Process for the production of a novel derivative of a-phenylethyl alcohol, characterized in that, according to known Aqueous solutions of salts of the acid succinic acid ester obtained by methods of the a-phenylethyl alcohol mixed with excess calcium chloride.
DEP19118D 1948-10-22 1948-10-22 Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols Expired DE810027C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEP19118D DE810027C (en) 1948-10-22 1948-10-22 Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEP19118D DE810027C (en) 1948-10-22 1948-10-22 Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols

Publications (1)

Publication Number Publication Date
DE810027C true DE810027C (en) 1951-08-06

Family

ID=7367328

Family Applications (1)

Application Number Title Priority Date Filing Date
DEP19118D Expired DE810027C (en) 1948-10-22 1948-10-22 Process for the production of a novel Abkoemmlings des ‡ -Phenylaethylalkohols

Country Status (1)

Country Link
DE (1) DE810027C (en)

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