DE69936195D1 - Pharmazeutische gelformulierung enthaltend eine trizyklische substanz (fk-506/tacrolimus) - Google Patents
Pharmazeutische gelformulierung enthaltend eine trizyklische substanz (fk-506/tacrolimus)Info
- Publication number
- DE69936195D1 DE69936195D1 DE69936195T DE69936195T DE69936195D1 DE 69936195 D1 DE69936195 D1 DE 69936195D1 DE 69936195 T DE69936195 T DE 69936195T DE 69936195 T DE69936195 T DE 69936195T DE 69936195 D1 DE69936195 D1 DE 69936195D1
- Authority
- DE
- Germany
- Prior art keywords
- tacrolimus
- formulation containing
- gel formulation
- pharmaceutical gel
- tricyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11727198 | 1998-04-27 | ||
JP11727198 | 1998-04-27 | ||
PCT/JP1999/002237 WO1999055332A1 (fr) | 1998-04-27 | 1999-04-26 | Compositions medicinales |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69936195D1 true DE69936195D1 (de) | 2007-07-12 |
DE69936195T2 DE69936195T2 (de) | 2007-09-13 |
Family
ID=14707636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69936195T Expired - Lifetime DE69936195T2 (de) | 1998-04-27 | 1999-04-26 | Pharmazeutische gelformulierung enthaltend eine trizyklische substanz (fk-506/tacrolimus) |
Country Status (24)
Country | Link |
---|---|
US (2) | US6673808B1 (de) |
EP (1) | EP1074255B1 (de) |
JP (1) | JP3732525B2 (de) |
KR (1) | KR100406823B1 (de) |
CN (1) | CN1161117C (de) |
AR (1) | AR018330A1 (de) |
AT (1) | ATE363275T1 (de) |
AU (1) | AU749475B2 (de) |
BR (1) | BR9910336A (de) |
CA (1) | CA2326222C (de) |
DE (1) | DE69936195T2 (de) |
ES (1) | ES2284248T3 (de) |
HK (1) | HK1038884B (de) |
HU (1) | HUP0104452A3 (de) |
ID (1) | ID29262A (de) |
IL (1) | IL139210A (de) |
NO (1) | NO20005399L (de) |
NZ (1) | NZ507345A (de) |
PL (1) | PL343627A1 (de) |
RU (1) | RU2203058C2 (de) |
TR (1) | TR200003108T2 (de) |
TW (1) | TW565461B (de) |
WO (1) | WO1999055332A1 (de) |
ZA (1) | ZA200005378B (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9826656D0 (en) | 1998-12-03 | 1999-01-27 | Novartis Ag | Organic compounds |
EP1173177B2 (de) * | 1999-04-30 | 2014-03-05 | Sucampo AG | Verwendung von makroliden zur behandlung von trockenen augen |
US7063857B1 (en) | 1999-04-30 | 2006-06-20 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
PT2269603E (pt) * | 2001-02-19 | 2015-09-09 | Novartis Ag | Tratamento de tumores da mama com um derivado de rapamicina em combinação com exemestano |
GB0108498D0 (en) * | 2001-04-04 | 2001-05-23 | Novartis Ag | Organic Compounds |
AUPR529701A0 (en) * | 2001-05-28 | 2001-06-21 | Fujisawa Pharmaceutical Co., Ltd. | Pharmaceutical composition |
AR038628A1 (es) * | 2002-03-04 | 2005-01-19 | Novartis Ag | Composicion oftalmica |
GB0218996D0 (en) * | 2002-08-14 | 2002-09-25 | Novartis Ag | Organic compounds |
US7354574B2 (en) | 2002-11-07 | 2008-04-08 | Advanced Ocular Systems Limited | Treatment of ocular disease |
US7083802B2 (en) | 2003-07-31 | 2006-08-01 | Advanced Ocular Systems Limited | Treatment of ocular disease |
US7083803B2 (en) | 2003-09-19 | 2006-08-01 | Advanced Ocular Systems Limited | Ocular solutions |
US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
KR101284710B1 (ko) | 2004-03-03 | 2013-07-23 | 레반스 테라퓨틱스, 아이엔씨. | 국소 진단제 및 치료제의 수송을 위한 조성물 및 방법 |
JP4579920B2 (ja) * | 2004-06-24 | 2010-11-10 | 興和株式会社 | アトルバスタチン外用剤組成物 |
BRPI0608249A2 (pt) | 2005-03-03 | 2009-12-08 | Revance Therapeutics Inc | formulação, método para aplicação tópica e kit para distribuição transdérmica de toxina botulìnica |
PL1904056T3 (pl) | 2005-07-18 | 2009-09-30 | Minu Llc | Zastosowanie makrolidu do przywracania czucia rogówkowego |
FR2900052B1 (fr) * | 2006-04-19 | 2011-02-18 | Galderma Sa | Composition comprenant au moins une phase aqueuse et au moins une phase grasse comprenant de l'ivermectine |
CN101288643B (zh) * | 2008-06-17 | 2012-11-14 | 杨喜鸿 | 含有他克莫司的凝胶剂组合物及其制备方法和药物应用 |
US8575189B2 (en) * | 2008-10-08 | 2013-11-05 | Takata Seiyaku Co., Ltd. | Tacrolimus preparation for external applications |
GB0917816D0 (en) | 2009-10-12 | 2009-11-25 | Biotica Tech Ltd | Novel compounds and methods for their production |
GB0917817D0 (en) | 2009-10-12 | 2009-11-25 | Biotica Tech Ltd | Novel compounds and methods for their production |
JP2011102260A (ja) * | 2009-11-11 | 2011-05-26 | Takada Seiyaku Kk | タクロリムス外用剤 |
JP5674786B2 (ja) * | 2010-07-23 | 2015-02-25 | マルホ株式会社 | タクロリムスを含有する水中油型クリーム状組成物 |
WO2012011192A1 (ja) * | 2010-07-23 | 2012-01-26 | マルホ株式会社 | タクロリムスを含有する水中油型クリーム状組成物 |
WO2012105521A1 (ja) * | 2011-01-31 | 2012-08-09 | 国立大学法人大阪大学 | 皮膚疾患を処置するための外用薬およびその製造方法 |
AU2021211317A1 (en) * | 2020-01-24 | 2022-09-01 | Nobelpharma Co., Ltd. | External preparation containing rapamycin |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4454113A (en) * | 1982-09-21 | 1984-06-12 | Scm Corporation | Stabilization of oil and water emulsions using polyglycerol esters of fatty acids |
US5540931A (en) * | 1989-03-03 | 1996-07-30 | Charles W. Hewitt | Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants |
US4996193A (en) * | 1989-03-03 | 1991-02-26 | The Regents Of The University Of California | Combined topical and systemic method of administration of cyclosporine |
US4973468A (en) * | 1989-03-22 | 1990-11-27 | Cygnus Research Corporation | Skin permeation enhancer compositions |
ES2099112T3 (es) * | 1990-09-04 | 1997-05-16 | Fujisawa Pharmaceutical Co | Pomadas que contienen un compuesto triciclico. |
TW213418B (de) * | 1991-05-02 | 1993-09-21 | Kuko Seiyaku Kk | |
JPH06128148A (ja) * | 1992-04-30 | 1994-05-10 | Dotsuto:Kk | 皮膚外用剤 |
JP2523428B2 (ja) * | 1992-12-04 | 1996-08-07 | エスエス製薬株式会社 | 消炎鎮痛ゲル製剤 |
JPH06345646A (ja) * | 1993-06-08 | 1994-12-20 | Fujisawa Pharmaceut Co Ltd | ローション剤 |
DK1147766T3 (da) * | 1994-10-26 | 2005-08-29 | Novartis Ag | Farmaceutiske sammensætninger |
HU224814B1 (en) | 1995-12-28 | 2006-02-28 | Mitsubishi Pharma Corp | Use of propane-1,3-diol derivative for the preparation of a medicament useful for the topical treating of inflammatory and immune diseases |
CZ283516B6 (cs) * | 1996-09-12 | 1998-04-15 | Galena A.S. | Léčivé přípravky, zejména pro vnitřní aplikaci, ve formě samomikroemulgujících terapeutických systémů |
TW450810B (en) * | 1997-02-20 | 2001-08-21 | Fujisawa Pharmaceutical Co | Macrolides antibiotic pharmaceutical composition for preventing and treating skin diseases |
EP0978288A4 (de) * | 1997-04-11 | 2006-07-12 | Astellas Pharma Inc | Medizinische zusammensetzung |
-
1999
- 1999-04-26 CN CNB998079367A patent/CN1161117C/zh not_active Expired - Fee Related
- 1999-04-26 PL PL99343627A patent/PL343627A1/xx not_active Application Discontinuation
- 1999-04-26 AU AU35372/99A patent/AU749475B2/en not_active Ceased
- 1999-04-26 BR BR9910336-2A patent/BR9910336A/pt not_active IP Right Cessation
- 1999-04-26 ID IDW20002464A patent/ID29262A/id unknown
- 1999-04-26 KR KR10-2000-7011259A patent/KR100406823B1/ko not_active IP Right Cessation
- 1999-04-26 EP EP99917179A patent/EP1074255B1/de not_active Expired - Lifetime
- 1999-04-26 WO PCT/JP1999/002237 patent/WO1999055332A1/ja active IP Right Grant
- 1999-04-26 RU RU2000129665/14A patent/RU2203058C2/ru not_active IP Right Cessation
- 1999-04-26 DE DE69936195T patent/DE69936195T2/de not_active Expired - Lifetime
- 1999-04-26 HU HU0104452A patent/HUP0104452A3/hu unknown
- 1999-04-26 NZ NZ507345A patent/NZ507345A/xx unknown
- 1999-04-26 ES ES99917179T patent/ES2284248T3/es not_active Expired - Lifetime
- 1999-04-26 CA CA002326222A patent/CA2326222C/en not_active Expired - Fee Related
- 1999-04-26 TR TR2000/03108T patent/TR200003108T2/xx unknown
- 1999-04-26 IL IL13921099A patent/IL139210A/xx not_active IP Right Cessation
- 1999-04-26 AR ARP990101921A patent/AR018330A1/es unknown
- 1999-04-26 AT AT99917179T patent/ATE363275T1/de not_active IP Right Cessation
- 1999-04-26 US US09/673,260 patent/US6673808B1/en not_active Expired - Fee Related
- 1999-04-26 JP JP54808699A patent/JP3732525B2/ja not_active Expired - Fee Related
- 1999-04-27 TW TW088106893A patent/TW565461B/zh active
-
2000
- 2000-10-03 ZA ZA200005378A patent/ZA200005378B/en unknown
- 2000-10-26 NO NO20005399A patent/NO20005399L/no not_active Application Discontinuation
-
2001
- 2001-12-07 US US10/005,645 patent/US6586444B2/en not_active Expired - Fee Related
-
2002
- 2002-01-22 HK HK02100502.9A patent/HK1038884B/zh not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69936195D1 (de) | Pharmazeutische gelformulierung enthaltend eine trizyklische substanz (fk-506/tacrolimus) | |
DE69726015D1 (de) | Pharmazeutische zusammensetzung enthaltend koenzym q-10 | |
ATE234078T1 (de) | Pharmazeutische omeprazol-formulierung | |
DE69525148D1 (de) | Pharmazeutische formulierung | |
DE69814091D1 (de) | Voriconazol-enthaltende pharmazeutische zubereitungen | |
ATE228823T1 (de) | Pharmazeutische aerosolformulierung | |
DE69940904D1 (de) | Pharmazeutische zusammensetzung enthaltend epothilone | |
ATE331529T1 (de) | Antigen enthaltende pharmazeutische zusammensetzung | |
DE69924999D1 (de) | Lipasehemmer enthaltende pharmazeutische zusammensetzungen | |
DE59712959D1 (de) | Orale pharmazeutische zubereitung enthaltend ibandronat | |
NO953874D0 (no) | Farmasöytisk preparat inneholdende lipofile legemidler | |
HUP0004534A3 (en) | Pharmaceutical formulation containing olanzapine | |
DE69831620D1 (de) | Arzneizubereitungen enthaltend Kannabinoide | |
DE69807420D1 (de) | Pharmazeutische aerosolzusammensetzung | |
ATE307571T1 (de) | Pharmazeutische formulierung enthaltend bicalutamid | |
ATE432707T1 (de) | Pharmazeutische zubereitung | |
ATE383868T1 (de) | Pharmazeutische formulierung enthaltend megalatran und dessen pro-pharmaka | |
DE10084344T1 (de) | Cyclosporin enthaltende pharmazeutische Zusammensetzung | |
DE59801987D1 (de) | Pharmazeutische zusammensetzung enthaltend peptichemio | |
DE69708130T2 (de) | A-oxo-butansäuren enthaltende pharmazeutische zusammensetzung | |
ATE260094T1 (de) | Mikronisierte bicyclische arzneistoffe enthaltende pharmazeutische zusammensetzungen | |
ID30032A (id) | Formulasi farmasi | |
DE69907735D1 (de) | Melatoninderivate und diese enthaltende pharmazeutische zubereitung | |
AR025867A1 (es) | Formulacion portasdora farmaceutica | |
NO20004816D0 (no) | Ny farmasøytisk formulering |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |