DE69935085D1 - Verfahren und Zusammensetzung zur Hemmung des neoplastischen Zellwachstums - Google Patents
Verfahren und Zusammensetzung zur Hemmung des neoplastischen ZellwachstumsInfo
- Publication number
- DE69935085D1 DE69935085D1 DE69935085T DE69935085T DE69935085D1 DE 69935085 D1 DE69935085 D1 DE 69935085D1 DE 69935085 T DE69935085 T DE 69935085T DE 69935085 T DE69935085 T DE 69935085T DE 69935085 D1 DE69935085 D1 DE 69935085D1
- Authority
- DE
- Germany
- Prior art keywords
- present
- polypeptides
- methods
- cell growth
- neoplastic cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11329698P | 1998-12-22 | 1998-12-22 | |
US113296P | 1998-12-22 | ||
PCT/US1999/005028 WO1999046281A2 (en) | 1998-03-10 | 1999-03-08 | Novel polypeptides and nucleic acids encoding the same |
WOPCT/US99/05028 | 1999-03-08 | ||
US13023299P | 1999-04-21 | 1999-04-21 | |
US130232P | 1999-04-21 | ||
US13144599P | 1999-04-28 | 1999-04-28 | |
US131445P | 1999-04-28 | ||
US13428799P | 1999-05-14 | 1999-05-14 | |
US134287P | 1999-05-14 | ||
US14475899P | 1999-07-20 | 1999-07-20 | |
US144758P | 1999-07-20 | ||
US14569899P | 1999-07-26 | 1999-07-26 | |
US145698P | 1999-07-26 | ||
PCT/US1999/021090 WO2000015796A2 (en) | 1998-09-16 | 1999-09-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WOPCT/US99/21090 | 1999-09-15 | ||
WOPCT/US99/21547 | 1999-09-15 | ||
PCT/US1999/021547 WO2000015797A2 (en) | 1998-09-17 | 1999-09-15 | Compositions and methods for the treatment of immune related diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69935085D1 true DE69935085D1 (de) | 2007-03-22 |
DE69935085T2 DE69935085T2 (de) | 2007-08-23 |
Family
ID=27557838
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69935085T Expired - Lifetime DE69935085T2 (de) | 1998-12-22 | 1999-12-02 | Verfahren und Zusammensetzung zur Hemmung des neoplastischen Zellwachstums |
DE69940964T Expired - Lifetime DE69940964D1 (de) | 1998-12-22 | 1999-12-02 | Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69940964T Expired - Lifetime DE69940964D1 (de) | 1998-12-22 | 1999-12-02 | Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1141284A2 (de) |
JP (5) | JP3993746B2 (de) |
KR (1) | KR100499600B1 (de) |
AT (2) | ATE353339T1 (de) |
AU (1) | AU768230B2 (de) |
CA (1) | CA2353799A1 (de) |
DE (2) | DE69935085T2 (de) |
DK (1) | DK1484338T3 (de) |
ES (2) | ES2327785T3 (de) |
IL (3) | IL143031A0 (de) |
MX (1) | MXPA01006330A (de) |
PT (1) | PT1484338E (de) |
WO (1) | WO2000037638A2 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6392019B1 (en) | 1997-11-22 | 2002-05-21 | John Ford | Antibodies specific for EGF motif proteins |
US6808890B2 (en) | 1999-07-28 | 2004-10-26 | Nuvelo, Inc. | Method of detecting a cancerous cell expressing EGFL6, and EGF mutif protein |
US7419663B2 (en) | 1998-03-20 | 2008-09-02 | Genentech, Inc. | Treatment of complement-associated disorders |
US8088386B2 (en) | 1998-03-20 | 2012-01-03 | Genentech, Inc. | Treatment of complement-associated disorders |
US7192589B2 (en) * | 1998-09-16 | 2007-03-20 | Genentech, Inc. | Treatment of inflammatory disorders with STIgMA immunoadhesins |
US8007798B2 (en) | 1997-11-21 | 2011-08-30 | Genentech, Inc. | Treatment of complement-associated disorders |
WO1999027096A1 (en) | 1997-11-22 | 1999-06-03 | Hyseq, Inc. | A NOVEL EGF MOTIF PROTEIN OBTAINED FROM A cDNA LIBRARY OF FETAL LIVER-SPLEEN |
NZ528700A (en) * | 1998-04-08 | 2005-02-25 | Genentech Inc | Novel PRO866 polypeptides and nucleic acids with homology to mindin and spondin proteins |
JP2002518010A (ja) | 1998-06-16 | 2002-06-25 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 94個のヒト分泌タンパク質 |
US6960433B1 (en) | 1998-10-19 | 2005-11-01 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
CA2358684C (en) | 1999-01-15 | 2013-07-16 | Biogen, Inc. | Antagonists of tweak and of tweak receptor and their use to treat immunological disorders |
JP2003531811A (ja) * | 1999-03-08 | 2003-10-28 | ジェネンテック・インコーポレーテッド | 血管形成及び心臓血管新生の促進又は阻害 |
ES2291198T3 (es) * | 1999-07-20 | 2008-03-01 | Genentech, Inc. | Composiciones y procedimientos para el tratamiento de enfermedades de tipo inmunologico. |
RU2002115295A (ru) * | 1999-12-09 | 2004-01-10 | Санкио Компани, Лимитед (Jp) | Способ испытания терапевтического или профилактического средства от гиперлипидемии |
EP2163561A1 (de) * | 2000-01-12 | 2010-03-17 | Yale University | Rezeptorvermittelte NOGO-Blockade des axonalen Wachstums |
US7119165B2 (en) | 2000-01-12 | 2006-10-10 | Yale University | Nogo receptor-mediated blockade of axonal growth |
WO2001085193A2 (en) | 2000-05-08 | 2001-11-15 | Biogen, Inc. | Method for promoting neovascularization using a tweak agonist and an angiogenic factor |
US7208151B2 (en) | 2001-09-12 | 2007-04-24 | Biogen Idec Ma Inc. | Tweak receptor agonists as anti-angiogenic agents |
CA2424834A1 (en) | 2000-10-06 | 2002-04-11 | Yale University | Nogo receptor homologs |
US20020111302A1 (en) * | 2000-11-30 | 2002-08-15 | Y. Tom Tang | Novel nucleic acids and polypeptides |
EP2301578A3 (de) | 2002-04-09 | 2012-08-08 | Biogen Idec MA Inc. | Verfahren zur Behandlung TWEAK-assoziierter Erkrankungen |
CA2391438A1 (en) * | 2002-05-01 | 2003-11-01 | Procyon Biopharma Inc. | Psp94 diagnostic reagents and assays |
US20090124993A1 (en) | 2005-02-17 | 2009-05-14 | Burkly Linda C | Treating neurological disorders |
EP1885388B1 (de) | 2005-05-10 | 2013-09-11 | Biogen Idec MA Inc. | Behandlung und beurteilung von entzündlichen erkrankungen |
WO2006138219A2 (en) | 2005-06-13 | 2006-12-28 | Biogen Idec Ma Inc. | Methods of diagnosis / prognosis of inflammatory conditions |
US7893032B2 (en) | 2005-07-07 | 2011-02-22 | Yale University | NgR variants and compositions thereof for suppressing axonal growth inhibition |
WO2007056227A2 (en) | 2005-11-04 | 2007-05-18 | Genentech, Inc. | Use of complement pathway inhibitors to treat ocular diseases |
JP5524610B2 (ja) * | 2006-04-07 | 2014-06-18 | ザ リサーチ ファウンデーション オブ ステイト ユニバーシティー オブ ニューヨーク | トランスコバラミン受容体ポリペプチド、核酸およびその調節因子、ならびに細胞の増殖の調節ならびにガンおよびコバラミン欠損症の処置に使用する関連方法 |
US9044461B2 (en) | 2006-04-07 | 2015-06-02 | The Research Foundation Of State University Of New York | Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency |
US7776573B2 (en) | 2006-06-01 | 2010-08-17 | Genentech, Inc. | Crystal structure of CRIg and C3b:CRIg complex |
CN105085682A (zh) | 2006-11-02 | 2015-11-25 | 健泰科生物技术公司 | 人源化的抗-d因子抗体 |
AR066660A1 (es) | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
CN104558151A (zh) | 2008-05-06 | 2015-04-29 | 健泰科生物技术公司 | 亲和力成熟的CRIg变体 |
US9120858B2 (en) | 2011-07-22 | 2015-09-01 | The Research Foundation Of State University Of New York | Antibodies to the B12-transcobalamin receptor |
KR20160042438A (ko) | 2013-08-12 | 2016-04-19 | 제넨테크, 인크. | 보체-연관 상태의 치료를 위한 조성물 및 방법 |
PE20161440A1 (es) | 2014-05-01 | 2017-01-26 | Genentech Inc | Variantes del anticuerpo anti-factor d y sus usos |
CN108472382A (zh) | 2015-10-30 | 2018-08-31 | 豪夫迈·罗氏有限公司 | 抗-因子d抗体变体缀合物及其用途 |
CN108289951A (zh) | 2015-10-30 | 2018-07-17 | 豪夫迈·罗氏有限公司 | 抗-因子d抗体和缀合物 |
CN114835774B (zh) * | 2022-06-29 | 2022-09-27 | 中国农业大学 | 辣椒籽分离的寡肽msl及其在预防或治疗癌症中的应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ226799A (en) * | 1987-11-06 | 1991-08-27 | Oncogen | Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor |
US5814307A (en) * | 1989-04-10 | 1998-09-29 | Bristol-Myers Squibb Company | Method for regulating cell growth, leukocyte differentiation and tumor cell growth using Oncostatin M to stimulate synthesis of IL-6 |
US5416192A (en) * | 1990-04-03 | 1995-05-16 | Bristol-Myers Squibb Company | Epithelins: novel cysteine-rich growth modulating proteins |
US5028099A (en) * | 1990-08-08 | 1991-07-02 | Bertucco Leonard J | Trash recycling container |
US6030831A (en) * | 1997-09-19 | 2000-02-29 | Genetech, Inc. | Tie ligand homologues |
WO1999055869A1 (en) * | 1998-04-27 | 1999-11-04 | Zymogenetics, Inc. | Novel polypeptide growth factors and materials and methods for making them |
SV1999000069A (es) * | 1998-06-02 | 2000-04-11 | Lilly Co Eli | Angiopoyetina relacionada con secuencia del gen 3 en la cicatrizacion de la cara ref. x-12261 |
JP7039446B2 (ja) * | 2018-11-29 | 2022-03-22 | 株式会社東芝 | 電子装置 |
-
1999
- 1999-12-02 ES ES07001711T patent/ES2327785T3/es not_active Expired - Lifetime
- 1999-12-02 WO PCT/US1999/028565 patent/WO2000037638A2/en active Search and Examination
- 1999-12-02 MX MXPA01006330A patent/MXPA01006330A/es not_active Application Discontinuation
- 1999-12-02 AU AU17499/00A patent/AU768230B2/en not_active Expired
- 1999-12-02 EP EP99960644A patent/EP1141284A2/de not_active Withdrawn
- 1999-12-02 DK DK04007617T patent/DK1484338T3/da active
- 1999-12-02 DE DE69935085T patent/DE69935085T2/de not_active Expired - Lifetime
- 1999-12-02 AT AT04007617T patent/ATE353339T1/de active
- 1999-12-02 ES ES04007617T patent/ES2281704T3/es not_active Expired - Lifetime
- 1999-12-02 IL IL14303199A patent/IL143031A0/xx not_active IP Right Cessation
- 1999-12-02 DE DE69940964T patent/DE69940964D1/de not_active Expired - Lifetime
- 1999-12-02 CA CA002353799A patent/CA2353799A1/en not_active Abandoned
- 1999-12-02 KR KR10-2001-7007850A patent/KR100499600B1/ko not_active IP Right Cessation
- 1999-12-02 PT PT04007617T patent/PT1484338E/pt unknown
- 1999-12-02 JP JP2000589692A patent/JP3993746B2/ja not_active Expired - Fee Related
- 1999-12-02 AT AT07001711T patent/ATE432987T1/de not_active IP Right Cessation
-
2005
- 2005-03-10 JP JP2005066570A patent/JP2005237383A/ja not_active Withdrawn
- 2005-03-10 JP JP2005066569A patent/JP4037876B2/ja not_active Expired - Lifetime
-
2007
- 2007-05-24 JP JP2007138468A patent/JP2007222180A/ja active Pending
- 2007-05-24 JP JP2007138469A patent/JP2007291116A/ja active Pending
- 2007-09-20 IL IL186154A patent/IL186154A0/en unknown
- 2007-09-20 IL IL186153A patent/IL186153A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2005245451A (ja) | 2005-09-15 |
AU1749900A (en) | 2000-07-12 |
IL143031A0 (en) | 2002-04-21 |
ATE432987T1 (de) | 2009-06-15 |
KR20010084882A (ko) | 2001-09-06 |
ES2327785T3 (es) | 2009-11-03 |
AU768230B2 (en) | 2003-12-04 |
IL186153A0 (en) | 2008-01-20 |
WO2000037638A3 (en) | 2000-11-09 |
MXPA01006330A (es) | 2002-07-02 |
DE69940964D1 (de) | 2009-07-16 |
CA2353799A1 (en) | 2000-06-29 |
JP4037876B2 (ja) | 2008-01-23 |
ATE353339T1 (de) | 2007-02-15 |
IL186154A0 (en) | 2008-01-20 |
DK1484338T3 (da) | 2007-06-11 |
EP1141284A2 (de) | 2001-10-10 |
DE69935085T2 (de) | 2007-08-23 |
JP2007222180A (ja) | 2007-09-06 |
ES2281704T3 (es) | 2007-10-01 |
PT1484338E (pt) | 2007-05-31 |
WO2000037638A2 (en) | 2000-06-29 |
JP2005237383A (ja) | 2005-09-08 |
JP2003529317A (ja) | 2003-10-07 |
JP3993746B2 (ja) | 2007-10-17 |
JP2007291116A (ja) | 2007-11-08 |
KR100499600B1 (ko) | 2005-07-07 |
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