DE69931756D1 - Regionen variabler schwerer ketten und variabler leichter ketten von antikörpern für humanes blutplättchen-glykoprotein ib alpha - Google Patents

Regionen variabler schwerer ketten und variabler leichter ketten von antikörpern für humanes blutplättchen-glykoprotein ib alpha

Info

Publication number
DE69931756D1
DE69931756D1 DE69931756T DE69931756T DE69931756D1 DE 69931756 D1 DE69931756 D1 DE 69931756D1 DE 69931756 T DE69931756 T DE 69931756T DE 69931756 T DE69931756 T DE 69931756T DE 69931756 D1 DE69931756 D1 DE 69931756D1
Authority
DE
Germany
Prior art keywords
alpha
antibody
variable light
variable
variable heavy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69931756T
Other languages
English (en)
Other versions
DE69931756T2 (de
Inventor
Jonathan L Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE69931756D1 publication Critical patent/DE69931756D1/de
Application granted granted Critical
Publication of DE69931756T2 publication Critical patent/DE69931756T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
DE69931756T 1998-10-30 1999-10-29 Regionen variabler schwerer ketten und variabler leichter ketten von antikörpern für humanes blutplättchen-glykoprotein ib alpha Expired - Lifetime DE69931756T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10627598P 1998-10-30 1998-10-30
US106275P 1998-10-30
PCT/US1999/025495 WO2000026667A1 (en) 1998-10-30 1999-10-29 Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein ib alpha

Publications (2)

Publication Number Publication Date
DE69931756D1 true DE69931756D1 (de) 2006-07-20
DE69931756T2 DE69931756T2 (de) 2007-05-24

Family

ID=22310524

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69931756T Expired - Lifetime DE69931756T2 (de) 1998-10-30 1999-10-29 Regionen variabler schwerer ketten und variabler leichter ketten von antikörpern für humanes blutplättchen-glykoprotein ib alpha

Country Status (8)

Country Link
EP (1) EP1051620B1 (de)
JP (1) JP2002529054A (de)
AT (1) ATE329263T1 (de)
AU (1) AU1458500A (de)
CA (1) CA2317808A1 (de)
DE (1) DE69931756T2 (de)
IL (1) IL137121A0 (de)
WO (1) WO2000026667A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9918788D0 (en) 1999-08-10 1999-10-13 Leuven K U Res & Dev Antithrombotic effect of platelet glycoprotein 1b blocking monoclonal Fab fragments
DE10019967A1 (de) * 2000-04-20 2001-10-25 Fenning Biomed Gmbh Dr Antikörper gegen natives gp96, deren Herstellung und Verwendung
US7658924B2 (en) 2001-10-11 2010-02-09 Amgen Inc. Angiopoietin-2 specific binding agents
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
CA2490280A1 (en) 2002-07-01 2004-01-08 Human Genome Sciences, Inc. Antibodies that specifically bind to reg iv
JP4660189B2 (ja) * 2002-07-03 2011-03-30 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 抗血小板自己抗体およびそのインヒビターに関連する組成物、方法およびキット
CA2505924A1 (en) * 2002-11-13 2004-05-27 Micromet Ag Method for identifying antigen specific b cells
EP1649001A2 (de) * 2003-06-30 2006-04-26 Bio-Technology General (Israel) Ltd. Antikörper und deren verwendungen
EP1749536A1 (de) * 2005-08-03 2007-02-07 Thrombotargets Europe, S.L. Aktivierte Stimulatoren des Faktors X als antihämorrhagisches Mittel für die topische Anwendung
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
EP2186829B1 (de) * 2008-11-14 2014-12-31 Canadian Blood Services Antikörper gegen GPIbalpha
ES2728115T3 (es) * 2009-10-30 2019-10-22 Janssen Biotech Inc Antagonistas de IL-17A
JP2023506772A (ja) * 2019-12-10 2023-02-20 シーシーオーエイ セラピューティクス （ハンヂョウ） カンパニー リミテッド ヒト化抗糖タンパク質ｉｂアルファ（ｇｐｉｂａｌｐｈａ）抗体
BR112022011957A2 (pt) * 2019-12-20 2022-09-06 Medimmune Llc Composições e métodos de tratamento de câncer com receptores de antígenos quiméricos visando glipicana 3
JP2023531920A (ja) * 2020-06-23 2023-07-26 カドモン コーポレイション，リミティド ライアビリティ カンパニー 抗ｐｄ－１抗体および融合タンパク質

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877155A (en) * 1995-03-17 1999-03-02 The Research Foundation Of State University Of New York Mimotopes and anti-mimotopes of human platelet glycoprotein Ib/IX
US5817748A (en) * 1995-03-17 1998-10-06 The Research Foundation Of State University Of New York Mimotopes of human Platelet glycoprotein Ib/IX

Also Published As

Publication number Publication date
CA2317808A1 (en) 2000-05-11
EP1051620A1 (de) 2000-11-15
WO2000026667A1 (en) 2000-05-11
DE69931756T2 (de) 2007-05-24
IL137121A0 (en) 2001-06-14
WO2000026667A9 (en) 2001-04-12
EP1051620A4 (de) 2005-01-12
JP2002529054A (ja) 2002-09-10
EP1051620B1 (de) 2006-06-07
ATE329263T1 (de) 2006-06-15
AU1458500A (en) 2000-05-22

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