DE69923595D1 - Herstellung von proteinen - Google Patents

Herstellung von proteinen

Info

Publication number
DE69923595D1
DE69923595D1 DE69923595T DE69923595T DE69923595D1 DE 69923595 D1 DE69923595 D1 DE 69923595D1 DE 69923595 T DE69923595 T DE 69923595T DE 69923595 T DE69923595 T DE 69923595T DE 69923595 D1 DE69923595 D1 DE 69923595D1
Authority
DE
Germany
Prior art keywords
proteins
preparation
protein
salt
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69923595T
Other languages
English (en)
Other versions
DE69923595T2 (de
Inventor
Seema Islam
Nigel Alan Sharp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE69923595D1 publication Critical patent/DE69923595D1/de
Application granted granted Critical
Publication of DE69923595T2 publication Critical patent/DE69923595T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69923595T 1998-12-23 1999-12-21 Herstellung von proteinen Expired - Lifetime DE69923595T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9828624 1998-12-23
GBGB9828624.8A GB9828624D0 (en) 1998-12-23 1998-12-23 Production of proteins
PCT/EP1999/010157 WO2000039282A1 (en) 1998-12-23 1999-12-21 Production of proteins

Publications (2)

Publication Number Publication Date
DE69923595D1 true DE69923595D1 (de) 2005-03-10
DE69923595T2 DE69923595T2 (de) 2006-04-06

Family

ID=10845019

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69923595T Expired - Lifetime DE69923595T2 (de) 1998-12-23 1999-12-21 Herstellung von proteinen

Country Status (9)

Country Link
US (1) US6740505B1 (de)
EP (1) EP1141238B1 (de)
JP (1) JP2002533117A (de)
AT (1) ATE288476T1 (de)
AU (1) AU2099800A (de)
DE (1) DE69923595T2 (de)
ES (1) ES2237200T3 (de)
GB (1) GB9828624D0 (de)
WO (1) WO2000039282A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007525176A (ja) * 2003-04-25 2007-09-06 イミュネックス・コーポレーション 組換えタンパク質発現の誘導剤
US20090023186A1 (en) * 2007-07-22 2009-01-22 Excellgene Sa Use of valproic acid for enhancing production of recombinant proteins in mammalian cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681718A (en) * 1986-03-14 1997-10-28 Celltech Limited Methods for enhanced production of tissue plasminogen activator in cell culture using alkanoic acids or salts thereof
GB8606386D0 (en) 1986-03-14 1986-04-23 Celltech Ltd Production of protein
WO1989006686A1 (en) 1988-01-13 1989-07-27 The Upjohn Company Enhanced production of cellular proteins using butyrate
US5378612A (en) * 1990-05-11 1995-01-03 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Culture medium for production of recombinant protein
US5705364A (en) * 1995-06-06 1998-01-06 Genentech, Inc. Mammalian cell culture process
ATE348173T1 (de) * 1999-04-26 2007-01-15 Genentech Inc Zellenzuchtverfahren für glycoproteine

Also Published As

Publication number Publication date
ES2237200T3 (es) 2005-07-16
GB9828624D0 (en) 1999-02-17
AU2099800A (en) 2000-07-31
WO2000039282A1 (en) 2000-07-06
JP2002533117A (ja) 2002-10-08
EP1141238A1 (de) 2001-10-10
ATE288476T1 (de) 2005-02-15
US6740505B1 (en) 2004-05-25
EP1141238B1 (de) 2005-02-02
DE69923595T2 (de) 2006-04-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition