DE69916816D1 - Verbesserter blutgerinnungstest - Google Patents

Verbesserter blutgerinnungstest

Info

Publication number
DE69916816D1
DE69916816D1 DE69916816T DE69916816T DE69916816D1 DE 69916816 D1 DE69916816 D1 DE 69916816D1 DE 69916816 T DE69916816 T DE 69916816T DE 69916816 T DE69916816 T DE 69916816T DE 69916816 D1 DE69916816 D1 DE 69916816D1
Authority
DE
Germany
Prior art keywords
plasma sample
coagulation
reagent
factor
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69916816T
Other languages
English (en)
Other versions
DE69916816T2 (de
Inventor
Thomas Exner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STAGO BV, AMSTERDAM, NL
Original Assignee
Gradipore Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gradipore Ltd filed Critical Gradipore Ltd
Publication of DE69916816D1 publication Critical patent/DE69916816D1/de
Application granted granted Critical
Publication of DE69916816T2 publication Critical patent/DE69916816T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/4609—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
    • G01N2333/4613—Snake venom
    • G01N2333/462—Snake venom from Agkistrodon sp., e.g. acutase, ACTE

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
DE69916816T 1998-02-02 1999-02-01 Verbesserter blutgerinnungstest Expired - Lifetime DE69916816T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPP159698 1998-02-02
AUPP1596A AUPP159698A0 (en) 1998-02-02 1998-02-02 Improved blood coagulation test
PCT/AU1999/000069 WO1999039212A1 (en) 1998-02-02 1999-02-01 Improved blood coagulation test

Publications (2)

Publication Number Publication Date
DE69916816D1 true DE69916816D1 (de) 2004-06-03
DE69916816T2 DE69916816T2 (de) 2004-09-30

Family

ID=3805873

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69916816T Expired - Lifetime DE69916816T2 (de) 1998-02-02 1999-02-01 Verbesserter blutgerinnungstest

Country Status (9)

Country Link
US (1) US6838251B1 (de)
EP (1) EP1068536B1 (de)
JP (1) JP4331891B2 (de)
AT (1) ATE265685T1 (de)
AU (1) AUPP159698A0 (de)
CA (1) CA2318250A1 (de)
DE (1) DE69916816T2 (de)
ES (1) ES2217739T3 (de)
WO (1) WO1999039212A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT947585E (pt) * 1998-03-19 2001-11-30 Instrumentation Lab Spa Metodo in vitro melhorado, kits e reagentes para a peaquisa de defeitos de coagulacao sanguinea
EP1367135A1 (de) 2002-05-29 2003-12-03 Pentapharm AG Verbessertes Verfahren zur Beurteilung der Thrombinbildung in Blutplasma
US7245215B2 (en) * 2005-02-10 2007-07-17 Pinc Solutions Position-tracking device for position-tracking system
CN102692511B (zh) * 2012-06-08 2015-04-15 上海太阳生物技术有限公司 蛋白c(pc)测定试剂盒(发色底物法)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3607559A1 (de) 1986-03-07 1987-09-10 Boehringer Mannheim Gmbh Verfahren zur photometrischen bestimmung der protein c- und/oder protein s-aktivitaet
DE3724443A1 (de) 1987-07-23 1989-02-02 Max Planck Gesellschaft Funktioneller test zur bestimmung der protein s-aktivitaet
SE464135B (sv) * 1989-07-14 1991-03-11 Kabivitrum Ab Foerfarande foer bestaemning av funktionell aktivitet av fritt protein s eller protein c i ett plasmaprov
JPH08501153A (ja) * 1992-09-04 1996-02-06 グラディポール リミテッド 液体の凝固／溶解を検出する方法および装置
AT402824B (de) * 1993-12-03 1997-09-25 Immuno Ag Test zur bestimmung der empfindlichkeit einer testprobe gegenüber aktiviertem protein c
AUPM731394A0 (en) * 1994-08-05 1994-09-01 Life Therapeutics Limited Improved activated protein c resistance test
DE4427785A1 (de) * 1994-08-08 1996-02-15 Behringwerke Ag Verfahren zum Nachweis von Störungen des Protein C/Protein S-Systems
US5780255A (en) * 1995-06-09 1998-07-14 Instrumentation Laboratory, S.P.A. Protein C pathway screening test
FR2764389B1 (fr) * 1997-06-06 1999-08-06 Stago Diagnostica Utilisation de venin de crotalus viridis helleri, procede et necessaire pour la determination de la reactivite de la proteine c activee

Also Published As

Publication number Publication date
EP1068536B1 (de) 2004-04-28
AUPP159698A0 (en) 1998-02-26
EP1068536A4 (de) 2002-09-04
CA2318250A1 (en) 1999-08-05
WO1999039212A1 (en) 1999-08-05
DE69916816T2 (de) 2004-09-30
ES2217739T3 (es) 2004-11-01
EP1068536A1 (de) 2001-01-17
US6838251B1 (en) 2005-01-04
JP2002502040A (ja) 2002-01-22
ATE265685T1 (de) 2004-05-15
JP4331891B2 (ja) 2009-09-16

Similar Documents

Publication Publication Date Title
Hemker et al. Thrombin generation in plasma: its assessment via the endogenous thrombin potential
Lange et al. Ecarin chromogenic assay–a new method for quantitative determination of direct thrombin inhibitors like hirudin
CA2252983C (en) Method for determining the anticoagulatory potential of a sample
He et al. A laboratory method for determination of overall haemostatic potential in plasma. I. Method design and preliminary results
US5051357A (en) Method and assay using inactivation of factors Va and VIIIa by activated Protein C to diagnose thrombic disease or assay for Protein C and kit therefor
JP4762472B2 (ja) 血液学的アッセイ及び試薬
US20090087870A1 (en) Hematological assay and kit
Walenga et al. The inhibition of the generation of thrombin and the antithrombotic effect of a pentasaccharide with sole anti-factor Xa activity
ATE311601T1 (de) Rekombinant-kaninchengewebefaktor basiertes prothrombinzeitreagenz
DE69021849D1 (de) Verfahren zur Bestimmung des Spiegels von exogenen und endogenen Gerinnungsfaktoren und von Protein C.
DE69018910D1 (de) Verfahren zur Bestimmung des endogenen Thrombinpotentials von Plasma und Blut und Reagenziensatz zur Verwendung in besagtem Verfahren.
JP2007052020A (ja) ヘパリン修飾成分を用いた第Ｘａ因子に基づくヘパリンアッセイ
AU1538202A (en) A reagent and kit for determining global coagulability and hemostatic potential
DE69916816D1 (de) Verbesserter blutgerinnungstest
AU2001284147B2 (en) Assay for soluble fibrin
Antovic et al. Does recombinant factor VIIa, apart from overall hemostasis, regulate TAFI dependent fibrinolysis? In vitro analysis using overall hemostasis potential (OHP) assay
US5753510A (en) Calibrator for use in test methods for detecting a defective coagulation factor V
Hoppensteadt et al. Validity of serine protease inhibition tests in the evaluation and monitoring of the effect of heparin and its fractions
HU216866B (hu) Eljárás és reagens fibrinogén meghatározására
HU219457B (hu) Meizotrombint, meizotrombin(des F1)-t vagy keverékeiket tartalmazó reagens, valamint tesztkészlet diagnosztikai célokra
Eichinger Thrombin generation and venous thromboembolism
Demir et al. Ecarin clotting time is sensitive to heparinoids: comparison of two different techniques
GB2368642A (en) Method for detecting, treating, and monitoring conditions associated with activation of the coagulation response
Andresen et al. Coagulation Inhibitor Potential: a study of assay variables
WO2003028627A3 (en) Method for detecting procoagulant conditions

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: OCTAPHARMA PLASMA,INC.,, CLARKSTON, GA

8327 Change in the person/name/address of the patent owner

Owner name: STAGO BV, AMSTERDAM, NL