DE69907005D1 - Verfahren zur herstellung einer zur nasalen zerstäubung lösung, die ein oder mehrere sexualhormone enthält - Google Patents

Verfahren zur herstellung einer zur nasalen zerstäubung lösung, die ein oder mehrere sexualhormone enthält

Info

Publication number
DE69907005D1
DE69907005D1 DE69907005T DE69907005T DE69907005D1 DE 69907005 D1 DE69907005 D1 DE 69907005D1 DE 69907005 T DE69907005 T DE 69907005T DE 69907005 T DE69907005 T DE 69907005T DE 69907005 D1 DE69907005 D1 DE 69907005D1
Authority
DE
Germany
Prior art keywords
solution containing
producing
spraying solution
sexual hormones
nasal spraying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69907005T
Other languages
English (en)
Other versions
DE69907005T2 (de
Inventor
Gilles Fonknechten
Patrick Wuthrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Application granted granted Critical
Publication of DE69907005D1 publication Critical patent/DE69907005D1/de
Publication of DE69907005T2 publication Critical patent/DE69907005T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69907005T 1998-10-14 1999-10-13 Verfahren zur herstellung einer zur nasalen zerstäubung lösung, die ein oder mehrere sexualhormone enthält Expired - Fee Related DE69907005T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9812836 1998-10-14
FR9812836A FR2784584B1 (fr) 1998-10-14 1998-10-14 Procede de preparation d'une solution pour pulverisation nasale contenant une ou plusieurs hormones sexuelles et une cyclodextrine
PCT/FR1999/002480 WO2000021503A1 (fr) 1998-10-14 1999-10-13 Procede de preparation d'une solution pour pulverisation nasale contenant une ou plusieurs hormones sexuelles et une cyclodextrine

Publications (2)

Publication Number Publication Date
DE69907005D1 true DE69907005D1 (de) 2003-05-22
DE69907005T2 DE69907005T2 (de) 2004-03-18

Family

ID=9531516

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69907005T Expired - Fee Related DE69907005T2 (de) 1998-10-14 1999-10-13 Verfahren zur herstellung einer zur nasalen zerstäubung lösung, die ein oder mehrere sexualhormone enthält

Country Status (21)

Country Link
EP (1) EP1121100B1 (de)
JP (1) JP3911125B2 (de)
KR (1) KR100462441B1 (de)
CN (1) CN1323198A (de)
AT (1) ATE237310T1 (de)
AU (1) AU756441B2 (de)
BR (1) BR9914532A (de)
CA (1) CA2346567C (de)
DE (1) DE69907005T2 (de)
DK (1) DK1121100T3 (de)
EA (1) EA003069B1 (de)
ES (1) ES2197672T3 (de)
FR (1) FR2784584B1 (de)
HK (1) HK1040201A1 (de)
HU (1) HUP0103968A3 (de)
NO (1) NO20011673L (de)
NZ (1) NZ510776A (de)
PL (1) PL347322A1 (de)
PT (1) PT1121100E (de)
WO (1) WO2000021503A1 (de)
ZA (1) ZA200102961B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2827516B1 (fr) * 2001-07-19 2003-09-19 Servier Lab Composition pharmaceutique pour l'administration par voie nasale d'estradiol et de norethisterone
WO2005018607A1 (ja) * 2003-08-20 2005-03-03 Ajinomoto Co., Inc. 溶解性を改善した医薬品製剤
GB2482868A (en) * 2010-08-16 2012-02-22 Franciscus Wilhelmus Henricus Maria Merkus A testosterone liquid spray formulation for oromucosal administration
EP2763679A4 (de) * 2011-10-07 2016-06-01 Univ Florida State Res Found Prophylaktische und postakute verwendung von progesteron für bessere behandlungsergebnisse bei gehirnerschütterung
ES2575676T3 (es) 2012-01-20 2016-06-30 Aratana Therapeutics Nv Composición de colirio
RU2753511C2 (ru) * 2017-05-31 2021-08-17 Аратана Терапьютикс, Инк. Композиция глазных капель

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8801670A (nl) * 1988-07-01 1990-02-01 Walter Adrianus Josephus Johan Farmaceutisch preparaat.
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
GB9012663D0 (en) * 1990-06-07 1990-08-01 Erba Carlo Spa Galenic formulations containing cyclodextrins
DE4207922A1 (de) * 1992-03-13 1993-09-23 Pharmatech Gmbh Wasserloesliche einschlussverbindungen und verfahren zu deren herstellung
BE1007402A5 (nl) * 1993-03-26 1995-06-06 Adir Nasale farmaceutische preparaten met progestagene stof.

Also Published As

Publication number Publication date
HUP0103968A2 (hu) 2002-04-29
KR20010073214A (ko) 2001-07-31
NO20011673D0 (no) 2001-04-03
DK1121100T3 (da) 2003-07-21
DE69907005T2 (de) 2004-03-18
CA2346567A1 (fr) 2000-04-20
HK1040201A1 (zh) 2002-05-31
PL347322A1 (en) 2002-03-25
ZA200102961B (en) 2001-11-20
AU6096799A (en) 2000-05-01
JP2002527374A (ja) 2002-08-27
EP1121100B1 (de) 2003-04-16
ES2197672T3 (es) 2004-01-01
BR9914532A (pt) 2001-11-06
JP3911125B2 (ja) 2007-05-09
PT1121100E (pt) 2003-07-31
NO20011673L (no) 2001-04-03
AU756441B2 (en) 2003-01-16
FR2784584B1 (fr) 2002-09-20
FR2784584A1 (fr) 2000-04-21
KR100462441B1 (ko) 2004-12-17
EA003069B1 (ru) 2002-12-26
EA200100316A1 (ru) 2002-02-28
NZ510776A (en) 2002-10-25
EP1121100A1 (de) 2001-08-08
HUP0103968A3 (en) 2002-06-28
ATE237310T1 (de) 2003-05-15
WO2000021503A1 (fr) 2000-04-20
CA2346567C (fr) 2005-06-14
CN1323198A (zh) 2001-11-21

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee