DE69905616D1 - Verfahren und zusammensetzung zur behandlung und vorbeugung von mycobacterium infektionen - Google Patents

Verfahren und zusammensetzung zur behandlung und vorbeugung von mycobacterium infektionen

Info

Publication number
DE69905616D1
DE69905616D1 DE69905616T DE69905616T DE69905616D1 DE 69905616 D1 DE69905616 D1 DE 69905616D1 DE 69905616 T DE69905616 T DE 69905616T DE 69905616 T DE69905616 T DE 69905616T DE 69905616 D1 DE69905616 D1 DE 69905616D1
Authority
DE
Germany
Prior art keywords
treating
composition
mycobacterium infections
preventing mycobacterium
preventing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69905616T
Other languages
English (en)
Other versions
DE69905616T2 (de
Inventor
Ze-Qi Xu
Yuh-Meei Lin
Michael T Flavin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sarawak MediChem Pharmaceuticals Inc
Original Assignee
Sarawak MediChem Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sarawak MediChem Pharmaceuticals Inc filed Critical Sarawak MediChem Pharmaceuticals Inc
Publication of DE69905616D1 publication Critical patent/DE69905616D1/de
Application granted granted Critical
Publication of DE69905616T2 publication Critical patent/DE69905616T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69905616T 1998-10-15 1999-10-14 Verfahren und zusammensetzung zur behandlung und vorbeugung von mycobacterium infektionen Expired - Lifetime DE69905616T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10440998P 1998-10-15 1998-10-15
PCT/US1999/023689 WO2000021514A2 (en) 1998-10-15 1999-10-14 Method and composition for treating and preventing tuberculosis

Publications (2)

Publication Number Publication Date
DE69905616D1 true DE69905616D1 (de) 2003-04-03
DE69905616T2 DE69905616T2 (de) 2003-08-14

Family

ID=22300328

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69905616T Expired - Lifetime DE69905616T2 (de) 1998-10-15 1999-10-14 Verfahren und zusammensetzung zur behandlung und vorbeugung von mycobacterium infektionen

Country Status (12)

Country Link
US (2) US6268393B1 (de)
EP (1) EP1143952B1 (de)
CN (1) CN1334727A (de)
AP (1) AP2001002115A0 (de)
AT (1) ATE233089T1 (de)
AU (1) AU1705400A (de)
CA (1) CA2346813A1 (de)
DE (1) DE69905616T2 (de)
EA (1) EA200100347A1 (de)
ID (1) ID29547A (de)
OA (1) OA11666A (de)
WO (1) WO2000021514A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6677350B1 (en) * 1999-09-22 2004-01-13 Advanced Life Sciences, Inc. Beta-fluoroethyl thiourea compounds and use
AU758744B2 (en) * 2000-10-31 2003-03-27 F. Hoffmann-La Roche Ag Methods for the analysis of non-proteinaceous components using a protease from a bacillus strain
EP1379529A2 (de) * 2001-03-16 2004-01-14 Sarawak Medichem Pharmaceuticals, Inc. Pyranocoumarin verbindungen als neue pharmakophore mit anti-tb activität
AU2003211734A1 (en) * 2002-03-08 2003-09-22 Kuraray Co., Ltd. Intermediates for production of (+)-calanolide a, processes for production of the intermediates and process for producing (+)-calanolide a with the same
US20040132708A1 (en) * 2002-05-01 2004-07-08 Wyeth Process for preparing 6-alkylidene penem derivatives
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
AR039476A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp Proceso para preparar derivados de 6-alquiliden penem
CA2574363A1 (en) * 2004-07-23 2006-02-02 Pharmacia & Upjohn Company Llc Enantioselective method for separating sustituted 2-trifluoromethyl-2h-chromene-3-carboxylic acid derivatives
MX2008001083A (es) * 2005-07-27 2008-03-19 Wyeth Corp Inhibidores de 6-alquiliden-penem b-lactamasa triciclicos y combinacion de antibioticos de beta-lactama: un antibiotico de amplio espectro.
WO2007016134A1 (en) * 2005-07-27 2007-02-08 Wyeth BICYCLIC 6-ALKYLIDENE-PENEM B-LACTAMASE INHIBITORS AND β-LACTAM ANTIBIOTIC COMBINATION: A BROAD SPECTRUM ANTIBIOTIC
GT200600380A (es) * 2005-08-24 2007-03-29 Proceso para la preparacion de inhibidores de beta-lactamasa
US9155792B2 (en) * 2006-02-13 2015-10-13 Trustees Of Boston University RecA inhibitors with antibiotic activity, compositions and methods of use
WO2008019292A2 (en) * 2006-08-04 2008-02-14 Trustees Of Boston University Compositions and methods for potentiating antibiotic activity
CA2704649C (en) * 2007-11-05 2015-02-17 Institute Of Mataria Medica, Chinese Academy Of Medical Sciences Tetracyclic dipyrano-coumarin compounds with anti-hiv and anti-mycobacterium tuberculosis activities
MY158809A (en) * 2010-09-22 2016-11-15 Craun Res Sdn Bhd Pharmaceutical compositions for calanolides, their derivatives and analogues, and process for producing the same
CN102516217B (zh) * 2011-12-15 2014-03-12 四川大学 手性二氢色原酮骨架化合物及不对称合成
US9572809B2 (en) * 2012-07-18 2017-02-21 Spero Trinem, Inc. Combination therapy to treat Mycobacterium diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591770A (en) 1992-03-31 1997-01-07 The United States Of America As Represented By The Department Of Health And Human Services Calanolide and related antiretroviral compounds, compositions, and uses thereof
CA2133080C (en) * 1992-03-31 2006-06-06 Michael R. Boyd Calanolide antiviral compounds, compositions and uses thereof
JPH08505146A (ja) 1992-12-23 1996-06-04 スミスクライン・ビーチャム・コーポレイション レトロウイルス阻害剤としてのクマリン誘導体
US6043271A (en) * 1994-08-03 2000-03-28 Sarawak Medichem Pharmaceuticals, Inc. Method for the preparation of (±)-calanolide A and intermediates thereof

Also Published As

Publication number Publication date
US20010027209A1 (en) 2001-10-04
AP2001002115A0 (en) 2001-06-30
CN1334727A (zh) 2002-02-06
EP1143952B1 (de) 2003-02-26
WO2000021514A3 (en) 2001-08-23
ID29547A (id) 2001-09-06
EP1143952A2 (de) 2001-10-17
EP1143952A3 (de) 2002-09-11
US6268393B1 (en) 2001-07-31
DE69905616T2 (de) 2003-08-14
EA200100347A1 (ru) 2001-10-22
ATE233089T1 (de) 2003-03-15
AU1705400A (en) 2000-05-01
OA11666A (en) 2004-12-08
WO2000021514A2 (en) 2000-04-20
CA2346813A1 (en) 2000-04-20

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