DE69841073D1 - Fibronektinbindungsprotein abgeleitete peptide, die nicht an fibronektin binden, antikörper dagegen und therapeutische anwendung - Google Patents

Fibronektinbindungsprotein abgeleitete peptide, die nicht an fibronektin binden, antikörper dagegen und therapeutische anwendung

Info

Publication number
DE69841073D1
DE69841073D1 DE69841073T DE69841073T DE69841073D1 DE 69841073 D1 DE69841073 D1 DE 69841073D1 DE 69841073 T DE69841073 T DE 69841073T DE 69841073 T DE69841073 T DE 69841073T DE 69841073 D1 DE69841073 D1 DE 69841073D1
Authority
DE
Germany
Prior art keywords
fibronectin
binding
antibodies
peptides
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69841073T
Other languages
English (en)
Inventor
Magnus Hoeoek
Joseph M Patti
Karen L House-Pompeo
Petro Speziale
Danny Joh
Martin J Mcgavin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Manitoba
Universita degli Studi di Pavia
Texas A&M University System
Original Assignee
University of Manitoba
Universita degli Studi di Pavia
Texas A&M University System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Manitoba , Universita degli Studi di Pavia, Texas A&M University System filed Critical University of Manitoba
Application granted granted Critical
Publication of DE69841073D1 publication Critical patent/DE69841073D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/305—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F)
    • G01N2333/31—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/315—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Streptococcus (G), e.g. Enterococci
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69841073T 1997-01-21 1998-01-21 Fibronektinbindungsprotein abgeleitete peptide, die nicht an fibronektin binden, antikörper dagegen und therapeutische anwendung Expired - Lifetime DE69841073D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3613997P 1997-01-21 1997-01-21
PCT/US1998/001222 WO1998031389A2 (en) 1997-01-21 1998-01-21 Fibronectin binding protein compositions, antibodies thereto, and methods of use

Publications (1)

Publication Number Publication Date
DE69841073D1 true DE69841073D1 (de) 2009-10-01

Family

ID=21886867

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69841073T Expired - Lifetime DE69841073D1 (de) 1997-01-21 1998-01-21 Fibronektinbindungsprotein abgeleitete peptide, die nicht an fibronektin binden, antikörper dagegen und therapeutische anwendung

Country Status (8)

Country Link
EP (1) EP0971740B1 (de)
JP (1) JP5124062B2 (de)
AT (1) ATE439862T1 (de)
AU (1) AU744723B2 (de)
CA (1) CA2277793A1 (de)
DE (1) DE69841073D1 (de)
NZ (1) NZ336781A (de)
WO (1) WO1998031389A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660842B1 (en) 1994-04-28 2003-12-09 Tripep Ab Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen
US6933366B2 (en) 1996-12-27 2005-08-23 Tripep Ab Specificity exchangers that redirect antibodies to bacterial adhesion receptors
US6692739B1 (en) 1998-08-31 2004-02-17 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
AU762978B2 (en) * 1998-08-31 2003-07-10 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
EP1109577B1 (de) * 1998-08-31 2009-02-11 Inhibitex, Inc. Multikomponenten Impfstoffe gegen Staphylococcus aureus
SE9804491D0 (sv) * 1998-12-22 1998-12-22 Bengt Guss Novel fibronectin-binding protein
US7115264B2 (en) 2001-11-05 2006-10-03 Inhibitex Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections
US7335359B2 (en) 2003-02-06 2008-02-26 Tripep Ab Glycosylated specificity exchangers
JP2007516157A (ja) 2003-02-06 2007-06-21 トリペップ アクチ ボラゲット グリコシル化された抗原／抗体又はリガンド／受容体特異***換体
BRPI0511429A (pt) * 2004-05-21 2007-12-11 Wyeth Corp proteìna de ligação à fibronectina (fnb) isolada, alterada de staphylococcal aureus (s. aureus); fnb isolada, alterada; composição imunogênica; método para imunizar um vertebrado contra s. aureus; vetor de expressão; célula hospedeira recombinante; método para produzir uma fnb alterada; método para induzir uma resposta imunológica em um vertebrado; proteìna isolada, alterada de ligação à fibronectina (fnb) de staphylococcal aureus (s. aureus); e molécula isolada de ácido nucléico que codifica uma fnb alterada de s. aureus
WO2006068077A1 (ja) * 2004-12-20 2006-06-29 Scientific Feed Laboratory Co., Ltd. 新型レンサ球菌症用魚病ワクチン
FR2935002B1 (fr) * 2008-08-13 2014-09-05 Biomerieux Sa Milieu de culture permettant de differencier staphylococcus aureus des staphylococcus a coagulase negative
EP2561888A1 (de) * 2011-08-23 2013-02-27 Deutsches Krebsforschungszentrum Protein enthaltend NC-1 zur Behandlung von Erkrankungen in Bezug auf Angiogenese

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8901687D0 (sv) * 1989-05-11 1989-05-11 Alfa Laval Agri Int Fibronectin binding protein as well as its preparation
SE9002617D0 (sv) * 1990-08-10 1990-08-10 Alfa Laval Agri Int A fibronectin binding peptide
CA2155413A1 (en) * 1993-02-05 1994-08-18 Martin Karl Russel Burnham Fibronectin binding protein; monoclonal antibody and their use in preventing bacterial adhesion
GB9415900D0 (en) * 1994-08-05 1994-09-28 Smithkline Beecham Plc Novel compounds and treatment
GB9415901D0 (en) * 1994-08-05 1994-09-28 Smithkline Beecham Plc Novel compounds and treatment

Also Published As

Publication number Publication date
WO1998031389A2 (en) 1998-07-23
WO1998031389A3 (en) 1999-01-21
AU744723B2 (en) 2002-02-28
JP5124062B2 (ja) 2013-01-23
CA2277793A1 (en) 1998-07-23
NZ336781A (en) 2002-10-25
EP0971740B1 (de) 2009-08-19
JP2002513398A (ja) 2002-05-08
AU6647998A (en) 1998-08-07
EP0971740A2 (de) 2000-01-19
ATE439862T1 (de) 2009-09-15

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