DE69831242D1 - Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen - Google Patents

Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen

Info

Publication number
DE69831242D1
DE69831242D1 DE69831242T DE69831242T DE69831242D1 DE 69831242 D1 DE69831242 D1 DE 69831242D1 DE 69831242 T DE69831242 T DE 69831242T DE 69831242 T DE69831242 T DE 69831242T DE 69831242 D1 DE69831242 D1 DE 69831242D1
Authority
DE
Germany
Prior art keywords
proteins
secretated
recombinant
seb1
transformed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831242T
Other languages
English (en)
Other versions
DE69831242T2 (de
Inventor
Sirkka Keraenen
Jaana Toikkanen
Ville Tieaho
Hans Soederlund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valtion Teknillinen Tutkimuskeskus
Original Assignee
Valtion Teknillinen Tutkimuskeskus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen Tutkimuskeskus filed Critical Valtion Teknillinen Tutkimuskeskus
Publication of DE69831242D1 publication Critical patent/DE69831242D1/de
Application granted granted Critical
Publication of DE69831242T2 publication Critical patent/DE69831242T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Seeds, Soups, And Other Foods (AREA)
DE69831242T 1997-07-09 1998-07-08 Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen Expired - Lifetime DE69831242T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI972909 1997-07-09
FI972909A FI972909A0 (fi) 1997-07-09 1997-07-09 Oekad produktion av avsoendrade proteiner genom rekombinatjaestceller
PCT/FI1998/000576 WO1999002716A1 (en) 1997-07-09 1998-07-08 Increased production of secreted proteins by recombinant yeast cells

Publications (2)

Publication Number Publication Date
DE69831242D1 true DE69831242D1 (de) 2005-09-22
DE69831242T2 DE69831242T2 (de) 2006-06-29

Family

ID=8549223

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831242T Expired - Lifetime DE69831242T2 (de) 1997-07-09 1998-07-08 Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen

Country Status (11)

Country Link
US (1) US6344341B1 (de)
EP (1) EP0994955B1 (de)
JP (1) JP2001509392A (de)
AT (1) ATE302282T1 (de)
AU (1) AU734541B2 (de)
CA (1) CA2296084A1 (de)
DE (1) DE69831242T2 (de)
DK (1) DK0994955T3 (de)
ES (1) ES2247704T3 (de)
FI (1) FI972909A0 (de)
WO (1) WO1999002716A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7968312B2 (en) 2004-06-16 2011-06-28 Dsm Ip Assets B.V. Production of polypeptides by improved secretion
WO2008053018A2 (en) 2006-11-02 2008-05-08 Dsm Ip Assets B.V. Improved production of secreted proteins by filamentous fungi
EP3000870B1 (de) * 2011-04-22 2018-01-24 Danisco US Inc. Fadenpilze mit einem veränderten viskositäts-phänotyp
SG11201608084TA (en) 2014-04-17 2016-10-28 Boehringer Ingelheim Rcv Gmbh Recombinant host cell engineered to overexpress helper proteins
CA2945877C (en) * 2014-04-17 2023-09-05 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell for expressing proteins of interest

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284044B1 (de) 1987-03-23 1994-03-23 Zymogenetics, Inc. Hohe Proteinsyntheserate in Hefe

Also Published As

Publication number Publication date
FI972909A0 (fi) 1997-07-09
EP0994955B1 (de) 2005-08-17
ATE302282T1 (de) 2005-09-15
US6344341B1 (en) 2002-02-05
CA2296084A1 (en) 1999-01-21
ES2247704T3 (es) 2006-03-01
AU734541B2 (en) 2001-06-14
AU8341098A (en) 1999-02-08
EP0994955A1 (de) 2000-04-26
JP2001509392A (ja) 2001-07-24
DK0994955T3 (da) 2005-11-28
DE69831242T2 (de) 2006-06-29
WO1999002716A1 (en) 1999-01-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: ZENZ PATENT- UND RECHTSANWAELTE, 45128 ESSEN