DE69827154D1 - Polymorphismuserkennung mit hilfe cluster-analyse - Google Patents

Polymorphismuserkennung mit hilfe cluster-analyse

Info

Publication number
DE69827154D1
DE69827154D1 DE69827154T DE69827154T DE69827154D1 DE 69827154 D1 DE69827154 D1 DE 69827154D1 DE 69827154 T DE69827154 T DE 69827154T DE 69827154 T DE69827154 T DE 69827154T DE 69827154 D1 DE69827154 D1 DE 69827154D1
Authority
DE
Germany
Prior art keywords
cluster analysis
polymorphism detection
sample polymers
differences
help
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69827154T
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English (en)
Other versions
DE69827154T2 (de
Inventor
Anthony Berno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymetrix Inc
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Affymetrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymetrix Inc filed Critical Affymetrix Inc
Application granted granted Critical
Publication of DE69827154D1 publication Critical patent/DE69827154D1/de
Publication of DE69827154T2 publication Critical patent/DE69827154T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
DE69827154T 1997-08-15 1998-08-14 Polymorphismuserkennung mit hilfe cluster-analyse Expired - Lifetime DE69827154T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5593997P 1997-08-15 1997-08-15
US55939P 1997-08-15
PCT/US1998/016971 WO1999009218A1 (en) 1997-08-15 1998-08-14 Polymorphism detection utilizing clustering analysis

Publications (2)

Publication Number Publication Date
DE69827154D1 true DE69827154D1 (de) 2004-11-25
DE69827154T2 DE69827154T2 (de) 2006-03-09

Family

ID=22001120

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69827154T Expired - Lifetime DE69827154T2 (de) 1997-08-15 1998-08-14 Polymorphismuserkennung mit hilfe cluster-analyse

Country Status (8)

Country Link
US (3) US6223127B1 (de)
EP (1) EP1019536B1 (de)
JP (1) JP2001514907A (de)
AT (1) ATE280246T1 (de)
AU (1) AU9198298A (de)
CA (1) CA2299625A1 (de)
DE (1) DE69827154T2 (de)
WO (1) WO1999009218A1 (de)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9198298A (en) * 1997-08-15 1999-03-08 Affymetrix, Inc. Polymorphism detection utilizing clustering analysis
US6979728B2 (en) 1998-05-04 2005-12-27 Baylor College Of Medicine Articles of manufacture and methods for array based analysis of biological molecules
US6699659B2 (en) * 1998-06-01 2004-03-02 Affymetrix, Inc. Products and methods for analyzing nucleic acids including identification of substitutions, insertions and deletions
US6245511B1 (en) * 1999-02-22 2001-06-12 Vialogy Corp Method and apparatus for exponentially convergent therapy effectiveness monitoring using DNA microarray based viral load measurements
US20040111219A1 (en) * 1999-02-22 2004-06-10 Sandeep Gulati Active interferometric signal analysis in software
US6142681A (en) 1999-02-22 2000-11-07 Vialogy Corporation Method and apparatus for interpreting hybridized bioelectronic DNA microarray patterns using self-scaling convergent reverberant dynamics
US6136541A (en) 1999-02-22 2000-10-24 Vialogy Corporation Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions
US20020052692A1 (en) * 1999-09-15 2002-05-02 Eoin D. Fahy Computer systems and methods for hierarchical cluster analysis of large sets of biological data including highly dense gene array data
WO2001029257A2 (en) * 1999-10-22 2001-04-26 Genset Methods of genetic cluster analysis
JP3563315B2 (ja) * 1999-12-14 2004-09-08 日立ソフトウエアエンジニアリング株式会社 樹状図表示方法及び樹状図表示システム
US20020067358A1 (en) * 2000-01-21 2002-06-06 Georg Casari Data analysis software
US20040101878A1 (en) * 2000-12-22 2004-05-27 Jones Michael H. High-throughput screening system by microarrays
US20020183936A1 (en) * 2001-01-24 2002-12-05 Affymetrix, Inc. Method, system, and computer software for providing a genomic web portal
EP1417629B1 (de) * 2001-07-06 2008-02-20 Lipomics Technologies, Inc. Erzeugen, betrachten, interpretieren und verwenden einer quantitativen datenbank von metaboliten
US6799122B2 (en) * 2001-08-31 2004-09-28 Conagra Grocery Products Company Method for identifying polymorphic markers in a population
DE60233743D1 (de) * 2001-09-24 2009-10-29 Lipomics Technologies Inc Verfahren zur verwendung von quantitativen lipidmetabolondaten
CA2470163A1 (en) * 2001-12-19 2003-07-03 Affymetrix, Inc. Array plates and method for constructing array plates
US7272506B2 (en) * 2002-03-01 2007-09-18 Applera Corporation Computer algorithm for automatic allele determination from fluorometer genotyping device
US7006680B2 (en) * 2002-05-03 2006-02-28 Vialogy Corp. System and method for characterizing microarray output data
US20050089909A1 (en) * 2002-05-31 2005-04-28 Mcgill University PTHrP-based prediction and diagnosis of bone disease
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
EP2112229A3 (de) 2002-11-25 2009-12-02 Sequenom, Inc. Verfahren zum Identifizieren des Brustkrebsrisikos und zugehörige Behandlungen
CA3084542A1 (en) 2003-06-10 2005-01-06 The Trustees Of Boston University Gene expression analysis of airway epithelial cells for diagnosing lung cancer
US7259258B2 (en) * 2003-12-17 2007-08-21 Illumina, Inc. Methods of attaching biological compounds to solid supports using triazine
US20050191682A1 (en) 2004-02-17 2005-09-01 Affymetrix, Inc. Methods for fragmenting DNA
US7035740B2 (en) * 2004-03-24 2006-04-25 Illumina, Inc. Artificial intelligence and global normalization methods for genotyping
US20050282174A1 (en) * 2004-06-19 2005-12-22 Webb Peter G Methods and systems for selecting nucleic acid probes for microarrays
WO2006022628A1 (en) * 2004-07-22 2006-03-02 Sequenom, Inc. Methods for identifying risk of type ii diabetes and treatments thereof
EP1792263A2 (de) * 2004-09-02 2007-06-06 Vialogy Corporation Erkennung von interessensereignissen unter verwendung von quantenresonanzinterferometrie
US20060073506A1 (en) 2004-09-17 2006-04-06 Affymetrix, Inc. Methods for identifying biological samples
US20060073511A1 (en) 2004-10-05 2006-04-06 Affymetrix, Inc. Methods for amplifying and analyzing nucleic acids
US7682782B2 (en) 2004-10-29 2010-03-23 Affymetrix, Inc. System, method, and product for multiple wavelength detection using single source excitation
EP1652580A1 (de) 2004-10-29 2006-05-03 Affymetrix, Inc. Mikroarray mit hohem Durchsatz, Arrayanordnung und Herstellungsverfahren für Arrays
EP2390347A1 (de) 2005-04-14 2011-11-30 Trustees Of Boston University Diagnose für Lungenerkrankungen mittels Klassenvorhersage
US20070173139A1 (en) * 2006-01-24 2007-07-26 Charles Gierke Fishing assembly
EP1999472A2 (de) 2006-03-09 2008-12-10 The Trustees Of Boston University Diagnose- und prognoseverfahren für lungenerkrankungen mittels genexpressionsprofilen aus nasenepithelzellen
EP3260556B1 (de) 2006-05-31 2019-07-31 Sequenom, Inc. Verfahren zur nukleinsäureextraktion aus einer probe
CA2654165A1 (en) 2006-06-05 2007-12-13 Cancer Care Ontario Assessment of risk for colorectal cancer
AU2007284651B2 (en) 2006-08-09 2014-03-20 Institute For Systems Biology Organ-specific proteins and methods of their use
US9845494B2 (en) 2006-10-18 2017-12-19 Affymetrix, Inc. Enzymatic methods for genotyping on arrays
JP2010508815A (ja) 2006-11-02 2010-03-25 イエール・ユニバーシテイ 卵母細胞受容能の評価
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
US7902345B2 (en) 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
US8165821B2 (en) * 2007-02-05 2012-04-24 Applied Biosystems, Llc System and methods for indel identification using short read sequencing
WO2008098142A2 (en) 2007-02-08 2008-08-14 Sequenom, Inc. Nucleic acid-based tests for rhd typing, gender determination and nucleic acid quantification
WO2008106785A1 (en) 2007-03-05 2008-09-12 Cancer Care Ontario Assessment of risk for colorectal cancer
CN101641452B (zh) 2007-03-26 2013-10-23 塞昆纳姆股份有限公司 限制性核酸内切酶增强的多态序列检测
US8200440B2 (en) 2007-05-18 2012-06-12 Affymetrix, Inc. System, method, and computer software product for genotype determination using probe array data
WO2009032781A2 (en) 2007-08-29 2009-03-12 Sequenom, Inc. Methods and compositions for universal size-specific polymerase chain reaction
WO2009113779A2 (ko) 2008-03-11 2009-09-17 국립암센터 Ｓｎｐ 어레이를 이용한 염색체, 유전자, 또는 특정 뉴클레오티드 서열의 카피 수 측정방법
EP2271772B1 (de) 2008-03-11 2014-07-16 Sequenom, Inc. Tests auf nukleinsäurebasis zur pränatalen geschlechtsbestimmung
EP2276858A4 (de) 2008-03-26 2011-10-05 Sequenom Inc Durch restriktionsendonuklease verbesserter nachweis polymorpher sequenzen
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
US20110212083A1 (en) 2008-11-06 2011-09-01 University Of Miami Office Of Technology Transfer Role of soluble upar in the pathogenesis of proteinuric kidney disease
ES2595410T3 (es) 2009-01-07 2016-12-29 Myriad Genetics, Inc. Biomarcadores de cáncer
EP2396661A4 (de) 2009-02-11 2013-10-30 Caris Mpi Inc Molekulare profilierung von tumoren
CA2755615A1 (en) * 2009-03-18 2010-09-23 Sequenom, Inc. Use of thermostable endonucleases for generating reporter molecules
EP3211095B1 (de) 2009-04-03 2019-01-02 Sequenom, Inc. Zusammensetzungen und verfahren für die herstellung von nukleinsäuren
CA2779223A1 (en) 2009-10-27 2011-05-12 Caris Mpi, Inc. Molecular profiling for personalized medicine
US20110201008A1 (en) * 2009-12-01 2011-08-18 University Of Miami Assays, methods and kits for measuring response to therapy and predicting clinical outcome in patients with b-cell lymphoma
US8501122B2 (en) 2009-12-08 2013-08-06 Affymetrix, Inc. Manufacturing and processing polymer arrays
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
ES2577017T3 (es) 2009-12-22 2016-07-12 Sequenom, Inc. Procedimientos y kits para identificar la aneuploidia
US9798855B2 (en) 2010-01-07 2017-10-24 Affymetrix, Inc. Differential filtering of genetic data
WO2011091435A2 (en) 2010-01-25 2011-07-28 Mount Sinai School Of Medicine Methods of treating liver disease
WO2011139714A2 (en) 2010-04-26 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase
US8961960B2 (en) 2010-04-27 2015-02-24 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases
CA2797271C (en) 2010-04-28 2021-05-25 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases
CA2797393C (en) 2010-04-29 2020-03-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases
CN103097523B (zh) 2010-04-29 2016-09-28 Atyr医药公司 与天冬酰胺酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
WO2011137368A2 (en) 2010-04-30 2011-11-03 Life Technologies Corporation Systems and methods for analyzing nucleic acid sequences
JP6008841B2 (ja) 2010-05-03 2016-10-19 エータイアー ファーマ， インコーポレイテッド メチオニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
CN105820252B (zh) 2010-05-03 2020-07-21 Atyr 医药公司 与苯丙氨酰-α-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
JP5976638B2 (ja) 2010-05-03 2016-08-23 エータイアー ファーマ， インコーポレイテッド アルギニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
AU2011248101B2 (en) 2010-05-04 2016-10-20 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-tRNA synthetase complex
EP2568996B1 (de) 2010-05-14 2017-10-04 aTyr Pharma, Inc. Therapeutische, diagnostische und antikörperhaltige zusammensetzungen im zusammenhang mit proteinfragmenten von phenylalanyl-beta-trna-synthetasen
AU2011258106B2 (en) 2010-05-27 2017-02-23 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases
US8962560B2 (en) 2010-06-01 2015-02-24 Atyr Pharma Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Lysyl-tRNA synthetases
CA2804391A1 (en) 2010-07-07 2012-01-12 Myriad Genetics, Inc. Gene signatures for cancer prognosis
CN103118695B (zh) 2010-07-12 2016-08-03 Atyr医药公司 与甘氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
EP2608801B1 (de) 2010-08-25 2019-08-21 aTyr Pharma, Inc. Innovative erkennung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen in zusammenhang mit proteinfragmenten von tyrosyl-trna-synthetasen
AU2012249531B2 (en) 2011-04-29 2017-06-29 Sequenom, Inc. Quantification of a minority nucleic acid species
EP2807271B1 (de) 2012-01-24 2018-08-22 CD Diagnostics, Inc. System zum nachweis einer infektion in der synovialflüssigkeit
DK2814514T3 (en) 2012-02-16 2017-12-18 Atyr Pharma Inc Histidyl tRNA synthetases for the treatment of autoimmune and inflammatory diseases
EP3321378B1 (de) 2012-02-27 2021-11-10 Becton, Dickinson and Company Zusammensetzungen für molekularen zählung
EP2820174B1 (de) 2012-02-27 2019-12-25 The University of North Carolina at Chapel Hill Verfahren und verwendung für molekulare tags
US9605313B2 (en) 2012-03-02 2017-03-28 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
CA2878979C (en) 2012-07-13 2021-09-14 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
EP4190918A1 (de) 2012-11-16 2023-06-07 Myriad Genetics, Inc. Gensignaturen zur krebsprognose
JP6309019B2 (ja) 2012-11-27 2018-04-11 ポンティフィシア・ウニベルシダッド・カトリカ・デ・チレＰｏｎｔｉｆｉｃｉａ Ｕｎｉｖｅｒｓｉｄａｄ Ｃａｔｏｌｉｃａ ｄｅ Ｃｈｉｌｅ 甲状腺腫瘍を診断するための組成物および方法
US9896728B2 (en) 2013-01-29 2018-02-20 Arcticrx Ltd. Method for determining a therapeutic approach for the treatment of age-related macular degeneration (AMD)
US11060145B2 (en) 2013-03-13 2021-07-13 Sequenom, Inc. Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus
ES2824248T3 (es) 2013-03-15 2021-05-11 Myriad Genetics Inc Genes y genes distintivos para el diagnóstico y tratamiento de melanoma
US10535420B2 (en) 2013-03-15 2020-01-14 Affymetrix, Inc. Systems and methods for probe design to detect the presence of simple and complex indels
US20140274749A1 (en) 2013-03-15 2014-09-18 Affymetrix, Inc. Systems and Methods for SNP Characterization and Identifying off Target Variants
CN107318267B (zh) 2013-08-12 2021-08-17 豪夫迈·罗氏有限公司 用于治疗补体相关的病症的组合物和方法
BR112016018205A8 (pt) 2014-02-08 2018-04-17 Genentech Inc métodos de tratamento de mal de alzheimer, de seleção de pacientes, de identificação de pacientes, de previsão, de otimização da eficácia terapêutica, kit, uso de agente e uso in vitro de agente
WO2015138774A1 (en) 2014-03-13 2015-09-17 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
EP3748011A1 (de) 2014-04-22 2020-12-09 Envirologix Inc. Zusammensetzungen und verfahren zur verbesserung und/oder vorhersage der dna-amplifikation
EP3143160B1 (de) 2014-05-13 2019-11-06 Myriad Genetics, Inc. Gensignaturen für krebsprognosen
EP4250299A3 (de) 2014-07-02 2023-12-06 Myriad myPath, LLC Gene und gensignaturen zur diagnose und behandlung von melanomen
EP4141128A1 (de) 2014-10-20 2023-03-01 Envirologix Inc. Zusammensetzungen und verfahren zum detektieren eines rna-virus
US10570441B2 (en) 2015-01-30 2020-02-25 Envirologix Inc. Compositions and methods for detecting nicking enzyme and polymerase activity using a substrate molecule
AU2016301231A1 (en) 2015-08-04 2018-02-22 Cd Diagnostics, Inc. Methods for detecting adverse local tissue reaction (ALTR) necrosis
US20180305748A1 (en) 2015-10-18 2018-10-25 Affymetrix, Inc. Multiallelic Genotyping of Single Nucleotide Polymorphisms and Indels
CA3005119A1 (en) 2015-11-19 2017-05-26 Myriad Genetics, Inc. Signatures for predicting cancer immune therapy response
CA3010240A1 (en) 2016-01-06 2017-07-13 Alexander Gutin Genes and gene signatures for diagnosis and treatment of melanoma
WO2017193062A1 (en) 2016-05-06 2017-11-09 Myriad Genetics, Inc. Gene signatures for renal cancer prognosis
WO2019126472A1 (en) 2017-12-22 2019-06-27 Genentech, Inc. Use of pilra binding agents for treatment of a disease
EP3807648A2 (de) 2018-06-18 2021-04-21 Igenomix S.L. Verfahren zur beurteilung der endometrialen transformation
EP3864165A4 (de) 2018-10-09 2022-08-03 Genecentric Therapeutics, Inc. Nachweis von ursprungskrebszellen
CA3121170A1 (en) 2018-11-30 2020-06-04 Caris Mpi, Inc. Next-generation molecular profiling
US20220220564A1 (en) 2019-04-17 2022-07-14 Igenomix, S.L. Improved methods for the early diagnosis of uterine leiomyomas and leiomyosarcomas
AU2020397802A1 (en) 2019-12-02 2022-06-16 Caris Mpi, Inc. Pan-cancer platinum response predictor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837832A (en) * 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
WO1995011995A1 (en) * 1993-10-26 1995-05-04 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
WO1997027317A1 (en) 1996-01-23 1997-07-31 Affymetrix, Inc. Nucleic acid analysis techniques
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
GB9521089D0 (en) * 1995-10-14 1995-12-20 Aromascan Plc Cluster analysis
WO1997029212A1 (en) * 1996-02-08 1997-08-14 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
AU9198298A (en) * 1997-08-15 1999-03-08 Affymetrix, Inc. Polymorphism detection utilizing clustering analysis

Also Published As

Publication number Publication date
ATE280246T1 (de) 2004-11-15
DE69827154T2 (de) 2006-03-09
EP1019536A4 (de) 2002-08-14
AU9198298A (en) 1999-03-08
US20040024537A1 (en) 2004-02-05
JP2001514907A (ja) 2001-09-18
EP1019536B1 (de) 2004-10-20
WO1999009218A1 (en) 1999-02-25
EP1019536A1 (de) 2000-07-19
CA2299625A1 (en) 1999-02-25
US20010041965A1 (en) 2001-11-15
US6584410B2 (en) 2003-06-24
US6223127B1 (en) 2001-04-24

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Owner name: AFFYMETRIX, INC. (N.D.GES.D.STAATES DELAWARE), SAN

8328 Change in the person/name/address of the agent

Representative=s name: HASELTINE LAKE PARTNERS GBR, 81669 MUENCHEN

8364 No opposition during term of opposition