DE69817167D1 - Verfahren zur herstellung von zwischenprodukten des carbapenems - Google Patents

Verfahren zur herstellung von zwischenprodukten des carbapenems

Info

Publication number
DE69817167D1
DE69817167D1 DE69817167T DE69817167T DE69817167D1 DE 69817167 D1 DE69817167 D1 DE 69817167D1 DE 69817167 T DE69817167 T DE 69817167T DE 69817167 T DE69817167 T DE 69817167T DE 69817167 D1 DE69817167 D1 DE 69817167D1
Authority
DE
Germany
Prior art keywords
carbapenem
intermediate products
producing intermediate
producing
synthesizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69817167T
Other languages
English (en)
Inventor
Nobuyoshi Yasuda
Chunhua Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9705855.6A external-priority patent/GB9705855D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69817167D1 publication Critical patent/DE69817167D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • C07F7/1872Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69817167T 1997-01-21 1998-01-16 Verfahren zur herstellung von zwischenprodukten des carbapenems Expired - Lifetime DE69817167D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3635797P 1997-01-21 1997-01-21
GBGB9705855.6A GB9705855D0 (en) 1997-03-21 1997-03-21 Process for synthesizing carbapenem intermediates
PCT/US1998/000874 WO1998031666A1 (en) 1997-01-21 1998-01-16 Process for synthesizing carbapenem intermediates

Publications (1)

Publication Number Publication Date
DE69817167D1 true DE69817167D1 (de) 2003-09-18

Family

ID=26311227

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69817167T Expired - Lifetime DE69817167D1 (de) 1997-01-21 1998-01-16 Verfahren zur herstellung von zwischenprodukten des carbapenems

Country Status (7)

Country Link
EP (1) EP0971889B1 (de)
JP (1) JP2001519773A (de)
AT (1) ATE247086T1 (de)
AU (1) AU722405B2 (de)
CA (1) CA2276365A1 (de)
DE (1) DE69817167D1 (de)
WO (1) WO1998031666A1 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5274188A (en) * 1987-05-04 1993-12-28 Ciba-Geigy Corporation Process for the manufacture of 4-acyloxy-3-hydroxyethyl-azetidinones
US4960879A (en) * 1988-03-23 1990-10-02 Shionogi & Co., Ltd. Process for carbapenem intermediates
ZA912279B (en) * 1990-04-09 1992-02-26 Hoffmann La Roche Carbapenem compounds

Also Published As

Publication number Publication date
JP2001519773A (ja) 2001-10-23
EP0971889A1 (de) 2000-01-19
AU5921598A (en) 1998-08-07
WO1998031666A1 (en) 1998-07-23
AU722405B2 (en) 2000-08-03
EP0971889B1 (de) 2003-08-13
ATE247086T1 (de) 2003-08-15
CA2276365A1 (en) 1998-07-23
EP0971889A4 (de) 2001-01-17

Similar Documents

Publication Publication Date Title
ATE217634T1 (de) 2,2-difluor-3-carbamoylribosesulfonat- verbindungen und verfahren zur herstellung von beta-nukleosiden
ATE282020T1 (de) Verfahren zur herstellung von 2-aminomalonsäure- derivaten
ATE240305T1 (de) Verfahren zur herstellung von 2- hydroxybenzamidderivaten
ATE207055T1 (de) Verfahren zur herstellung von 4-aryl-3- hydroxymethyl-piperidinen
DE69401197D1 (de) Verfahren zur herstellung von lithium diarylphosphiden und alkyl -derivaten davon-
DE69706382D1 (de) Verfahren zur herstellung von 2,2'-bipyrrolyl-pyrromethen-derivaten (prodigiosine)
DE60235365D1 (de) Verfahren zur herstellung von 7-amino-syn-3,5-dihydroxyheptansäurederivaten und zwischenverbindungen diesesverfahrens und deren herestellung
ATE261944T1 (de) Verfahren zur herstellung von carbamoylsubstituierten imidazolderivaten
ATE301659T1 (de) Verfahren zur herstellung von campothecinderivate
ATE191461T1 (de) Verfahren zur herstellung von alkoxyimino acetamid-derivaten
DE69431824D1 (de) Verfahren zur Herstellung von Schwefelhaltigen Imidazolderivaten und erhaltene Zwischenprodukte
DE69817167D1 (de) Verfahren zur herstellung von zwischenprodukten des carbapenems
ATE282594T1 (de) Verfahren zur herstellung von (+)-trans-4-p- fluorophenyl-3-hydroxymethyl-1-methylpiperidin
ATE165596T1 (de) Verfahren zur herstellung von insektiziden, acariziden und molluskiziden 2-halo-pyrrol-3- carbonitrilen
ATE155132T1 (de) Verfahren zur herstellung von amino- thiadiazolylacetylhaliden
ATE299498T1 (de) Verfahren zur herstellung von imidazolderivaten
DE69706504D1 (de) Verfahren zur herstellung von 3,4-dihydroxy-3-cyclobuten-1,2-dion
ATE212613T1 (de) Verfahren zur herstellung von 1,7-diaryl- oder 1, 7-diheteroarylheptan-4-olen und synthesezwischenprodukte
ATE175968T1 (de) Verfahren zur herstellung von kondensierten carbapenemderivaten
DE69712474D1 (de) Verfahren zur Herstellung von Diphosphonat-Derivaten
ATE208388T1 (de) Eintopfverfahren zur herstellung von 2- oxazolidinonderivate
ATE215071T1 (de) Verfahren zur herstellung von prostaglandin e1
ATE404540T1 (de) Verfahren zur herstellung von 1-substituierten 5- chlor-4methylpyrazolen
ATE240298T1 (de) Verfahren zur herstellung von chlorpyridinen
ATE263766T1 (de) Verfahren zur synthese von carbapenem- zwischenprodukten

Legal Events

Date Code Title Description
8332 No legal effect for de