DE69739544D1 - Virales material und mit multipler sklerose assoziierte nukleotidfragmente mit diagnostischen, prophylaktischen und therapeutischen verwendungen - Google Patents
Virales material und mit multipler sklerose assoziierte nukleotidfragmente mit diagnostischen, prophylaktischen und therapeutischen verwendungenInfo
- Publication number
- DE69739544D1 DE69739544D1 DE69739544T DE69739544T DE69739544D1 DE 69739544 D1 DE69739544 D1 DE 69739544D1 DE 69739544 T DE69739544 T DE 69739544T DE 69739544 T DE69739544 T DE 69739544T DE 69739544 D1 DE69739544 D1 DE 69739544D1
- Authority
- DE
- Germany
- Prior art keywords
- multiple sclerosis
- prophylactic
- diagnostic
- nucleotide fragments
- therapeutic uses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75642996A | 1996-11-26 | 1996-11-26 | |
PCT/IB1997/001482 WO1998023755A1 (en) | 1996-11-26 | 1997-11-26 | Viral material and nucleotide fragments associated with multiple sclerosis, for diagnostic, prophylactic and therapeutic purposes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69739544D1 true DE69739544D1 (de) | 2009-10-01 |
Family
ID=25043444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69739544T Expired - Lifetime DE69739544D1 (de) | 1996-11-26 | 1997-11-26 | Virales material und mit multipler sklerose assoziierte nukleotidfragmente mit diagnostischen, prophylaktischen und therapeutischen verwendungen |
Country Status (8)
Country | Link |
---|---|
US (3) | US6582703B2 (de) |
EP (1) | EP0942987B1 (de) |
JP (1) | JP4226657B2 (de) |
AT (1) | ATE440141T1 (de) |
CA (1) | CA2272845C (de) |
DE (1) | DE69739544D1 (de) |
ES (1) | ES2331496T3 (de) |
WO (1) | WO1998023755A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE440141T1 (de) * | 1996-11-26 | 2009-09-15 | Bio Merieux | Virales material und mit multipler sklerose assoziierte nukleotidfragmente mit diagnostischen,prophylaktischen und therapeutischen verwendungen |
US20040176314A1 (en) * | 1997-07-07 | 2004-09-09 | Bio Merieux | Endogenetic retroviral sequences, associated with autoimmune diseases or with pregnancy disorders |
FR2765588A1 (fr) * | 1997-07-07 | 1999-01-08 | Bio Merieux | Materiel nucleique retroviral et fragments nucleotidiques notamment associes a la sclerose en plaques et/ou la polyarthrite rhumatoide, a des fins de diagnostic, prophylactiques et therapeutiques |
DE19814925C2 (de) * | 1998-04-03 | 2000-10-05 | Thomas Harrer | Arzneimittel zur Induktion zytotoxischer T-Zellen |
FR2780069B1 (fr) * | 1998-06-23 | 2002-06-28 | Inst Nat Sante Rech Med | Famille de sequences nucleiques et de sequences proteiques deduites presentant des motifs retroviraux endogenes humains et leurs applications |
FR2788784A1 (fr) * | 1999-01-21 | 2000-07-28 | Bio Merieux | Fragment nucleique endogene associe a une maladie auto-immune, procede de marquage et reactif |
EP1029917A1 (de) * | 1999-02-15 | 2000-08-23 | Bio Merieux | Die LTR-Region von MSRV und die durch sie kodierten Proteine, und Sonden und Methoden für Detektion des MSRV-1 Retrovirus |
DE19921419A1 (de) * | 1999-05-08 | 2000-11-16 | Univ Ruprecht Karls Heidelberg | Verfahren zum spezifischen Nachweis und zur Identifizierung retroviraler Nukleinsäuren / Retroviren in einem Untersuchungsgut |
AU6785700A (en) * | 1999-08-20 | 2001-03-19 | Biogen, Inc. | Novel polynucleotides expressed in activated t-lymphocytes and proteins encoded thereby |
FR2805279B1 (fr) * | 2000-02-23 | 2004-09-24 | Jean Jacques Guilhou | Sequences retrovirales associees a des affections cutanees |
US7189800B2 (en) * | 2001-03-27 | 2007-03-13 | Samuel Bogoch | Replikin peptides in rapid replication of glioma cells and in influenza epidemics |
US7452963B2 (en) * | 2001-03-27 | 2008-11-18 | Samuel Bogoch | Replikin peptides and antibodies therefore |
KR100906102B1 (ko) * | 2001-03-27 | 2009-07-07 | 사무엘 보고치 | 레플리킨 펩타이드 및 그의 이용 |
US7774144B2 (en) * | 2001-10-26 | 2010-08-10 | Samuel Bogoch | System and method for identifying complex patterns of amino acids |
US7442761B2 (en) * | 2003-06-06 | 2008-10-28 | Samuel Bogoch | Replikin peptides and uses thereof |
US8494781B2 (en) * | 2003-06-06 | 2013-07-23 | Samuel Bogoch | Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds |
FR2863274B1 (fr) * | 2003-12-05 | 2012-11-16 | Commissariat Energie Atomique | Procede d'evaluation quantitative d'un rearrangement ou d'une recombinaison genetique ciblee d'un individu et ses applications. |
US9254315B2 (en) * | 2004-04-28 | 2016-02-09 | Samuel Bogoch | Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds |
CN101652385A (zh) * | 2006-05-30 | 2010-02-17 | 塞缪尔·博戈奇 | Replikin肽及其用途 |
AU2008253721A1 (en) * | 2007-01-18 | 2008-11-27 | Elenore S. Bogoch | Methods of determining lethality of pathogens and malignancies involving Replikin Peak Genes |
US20090269367A1 (en) * | 2008-04-23 | 2009-10-29 | Samuel Bogoch | Methods and compounds for mitigating pathogenic outbreaks using replikin count cycles |
US20100144589A1 (en) * | 2008-08-08 | 2010-06-10 | Samuel Bogoch | Methods of predicting cancer lethality using replikin counts |
US8680065B2 (en) * | 2008-09-11 | 2014-03-25 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Oligonucleotides of human endogenous retrovirus 9 (ERV-9) long terminal repeat (LTR) and methods of use |
US9233148B2 (en) * | 2009-01-09 | 2016-01-12 | Samuel Bogoch | Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza |
FR2984364A1 (fr) * | 2011-12-20 | 2013-06-21 | Biomerieux Sa | Procede pour le diagnostic ou le pronostic in vitro du cancer de l'ovaire |
FR2984360B1 (fr) * | 2011-12-20 | 2017-11-24 | Biomerieux Sa | Procede pour le diagnostic ou le pronostic in vitro du cancer du colon |
US10253353B2 (en) * | 2013-12-06 | 2019-04-09 | The Broad Institute, Inc. | Enhanced methods of ribonucleic acid hybridization |
GB201509395D0 (en) * | 2015-06-01 | 2015-07-15 | Univ Leicester | Improvements in and relating to nucleic acid probes |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ191327A (en) | 1978-08-24 | 1981-07-13 | W B Martin | Pasteurellosis vaccine comprising antigenic material derived from the a1 and a2 serotypes of pasteurella haemolytica |
US4311686A (en) | 1979-04-30 | 1982-01-19 | The Immunology Development Corporation | Methodology for the immunodiagnosis of multiple sclerosis and/or malignant diseases from blood sample analysis |
US4396600A (en) | 1980-12-18 | 1983-08-02 | Gus Gallucci | Adult schistosome worm-derived antigenic substance and method of obtaining same |
US4388298A (en) | 1982-07-14 | 1983-06-14 | The United States Of America As Represented By The Secretary Of Agriculture | Propagation of hemorrhagic enteritis virus in a turkey cell line and vaccine produced |
GB8324800D0 (en) | 1983-09-15 | 1983-10-19 | Pasteur Institut | Antigens |
US4520113A (en) | 1984-04-23 | 1985-05-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions |
US4647773A (en) | 1984-04-23 | 1987-03-03 | The United States Of America As Represented By The Department Of Health And Human Services | Method of continuous production of retroviruses (HTLV-III) from patients with AIDS and pre-AIDS |
NZ218050A (en) | 1985-11-13 | 1989-05-29 | Wistar Inst | Test for the presence of htlv-1v |
US4900553A (en) | 1987-09-11 | 1990-02-13 | Case Western Reserve University | Method of reducing glial scar formation and promoting axon and blood vessel growth and/or regeneration through the use of activated immature astrocytes |
EP0326395A2 (de) | 1988-01-29 | 1989-08-02 | City Of Hope | Verfahren zum Nachweis und zur Identifizierung von bestimmten viralen Sequenzien |
FR2651581B1 (fr) | 1989-09-06 | 1994-05-13 | Centre Nal Recherc Scientifique | Moyens pour le diagnostic de neuropathies demyelinisantes, en particulier de la sclerose en plaques. |
US5219837A (en) | 1990-06-21 | 1993-06-15 | Trustees Of The University Of Pennsylvania | Method of stimulating myelination of cells |
US5158976A (en) | 1990-10-29 | 1992-10-27 | The Children's Medical Center Corporation | Controlling glutamine/glutamate related neuronal injury |
DK173091D0 (da) | 1991-10-11 | 1991-10-11 | Schleroseforeningen The Danish | Biologisk materiale |
FR2689521B1 (fr) | 1992-04-03 | 1996-07-19 | Bio Merieux | Procede d'obtention et maintien d'une culture cellulaire viable, infectee par un virus associe a la sclerose en plaques, et produits biologiques derives de ladite culture. |
FR2689520B1 (fr) | 1992-04-03 | 1996-07-19 | Bio Merieux | Procede et milieu de culture pour l'obtention de cellules infectees par un virus associe a la sclerose en plaques. |
ATE314479T1 (de) | 1992-05-18 | 2006-01-15 | Genentech Inc | Aktivierung von rezeptoren fähig zur oligomerisierung durch verwendung von fusionierten rezeptor liganden |
GB9310657D0 (en) * | 1993-05-24 | 1993-07-07 | Univ London | Retrovirus |
WO1995021256A1 (fr) | 1994-02-04 | 1995-08-10 | Bio Merieux | Virus msrv1 et agent pathogene et/ou infectant msrv2 associes a la sclerose en plaques, leurs constituants nucleiques et leurs applications |
FR2716198B1 (fr) | 1994-02-15 | 1996-04-19 | Bio Merieux | Facteur cytotoxique tel qu'associé à la sclérose en plaques, sa détection et sa quantification. |
FR2731356B1 (fr) * | 1995-03-09 | 1997-04-30 | Bio Merieux | Virus msrv-1 et agent pathogene et/ou infectant msrv-2 associes a la polyarthrite rhumatoide |
FR2737500B1 (fr) * | 1995-08-03 | 1997-08-29 | Bio Merieux | Materiel viral et fragments nucleotidiques associes a la sclerose en plaques, a des fins de diagnostic, prophylactiques et therapeutiques |
ATE440141T1 (de) * | 1996-11-26 | 2009-09-15 | Bio Merieux | Virales material und mit multipler sklerose assoziierte nukleotidfragmente mit diagnostischen,prophylaktischen und therapeutischen verwendungen |
-
1997
- 1997-11-26 AT AT97911411T patent/ATE440141T1/de not_active IP Right Cessation
- 1997-11-26 ES ES97911411T patent/ES2331496T3/es not_active Expired - Lifetime
- 1997-11-26 DE DE69739544T patent/DE69739544D1/de not_active Expired - Lifetime
- 1997-11-26 CA CA002272845A patent/CA2272845C/en not_active Expired - Lifetime
- 1997-11-26 US US08/979,847 patent/US6582703B2/en not_active Expired - Lifetime
- 1997-11-26 WO PCT/IB1997/001482 patent/WO1998023755A1/en active Application Filing
- 1997-11-26 EP EP97911411A patent/EP0942987B1/de not_active Expired - Lifetime
- 1997-11-26 JP JP52447598A patent/JP4226657B2/ja not_active Expired - Lifetime
-
2002
- 2002-04-03 US US10/114,104 patent/US20030198647A1/en not_active Abandoned
-
2006
- 2006-10-16 US US11/581,030 patent/US7674888B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2272845C (en) | 2010-01-12 |
ATE440141T1 (de) | 2009-09-15 |
JP2001505768A (ja) | 2001-05-08 |
WO1998023755A1 (en) | 1998-06-04 |
EP0942987A1 (de) | 1999-09-22 |
US20070031452A1 (en) | 2007-02-08 |
US7674888B2 (en) | 2010-03-09 |
EP0942987B1 (de) | 2009-08-19 |
US20030198647A1 (en) | 2003-10-23 |
US6582703B2 (en) | 2003-06-24 |
CA2272845A1 (en) | 1998-06-04 |
US20030039664A1 (en) | 2003-02-27 |
JP4226657B2 (ja) | 2009-02-18 |
ES2331496T3 (es) | 2010-01-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |