DE69734829D1 - Infektiöse pseudovirale papillomavirus partikel - Google Patents
Infektiöse pseudovirale papillomavirus partikelInfo
- Publication number
- DE69734829D1 DE69734829D1 DE69734829T DE69734829T DE69734829D1 DE 69734829 D1 DE69734829 D1 DE 69734829D1 DE 69734829 T DE69734829 T DE 69734829T DE 69734829 T DE69734829 T DE 69734829T DE 69734829 D1 DE69734829 D1 DE 69734829D1
- Authority
- DE
- Germany
- Prior art keywords
- papillomavirus
- gene
- biological species
- infectious
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241001631646 Papillomaviridae Species 0.000 title abstract 4
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 230000002458 infectious effect Effects 0.000 title abstract 2
- 239000002245 particle Substances 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 241000894007 species Species 0.000 abstract 4
- 101710172711 Structural protein Proteins 0.000 abstract 2
- 210000000234 capsid Anatomy 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/084—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6009—Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
- Y10S977/916—Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2210496P | 1996-07-17 | 1996-07-17 | |
PCT/US1997/012115 WO1998002548A2 (en) | 1996-07-17 | 1997-07-14 | Infectious papillomavirus pseudoviral particles |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69734829D1 true DE69734829D1 (de) | 2006-01-12 |
Family
ID=21807834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69734829T Expired - Lifetime DE69734829D1 (de) | 1996-07-17 | 1997-07-14 | Infektiöse pseudovirale papillomavirus partikel |
Country Status (8)
Country | Link |
---|---|
US (2) | US6599739B1 (de) |
EP (1) | EP0922105B1 (de) |
JP (1) | JP2000515741A (de) |
AT (1) | ATE312178T1 (de) |
AU (1) | AU732125B2 (de) |
CA (1) | CA2257822A1 (de) |
DE (1) | DE69734829D1 (de) |
WO (1) | WO1998002548A2 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6267000A (en) * | 1999-06-30 | 2001-01-22 | Evotec Oai Ag | Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics |
US7476517B2 (en) | 1999-06-30 | 2009-01-13 | Evotec Ag | Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics |
US20040014033A1 (en) | 1999-06-30 | 2004-01-22 | Evotec Biosystems Ag, A Corporation Of Germany | Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics |
GB0007231D0 (en) | 2000-03-24 | 2000-05-17 | Chiron Spa | Modified rna for gene delivery |
DE60124725T2 (de) * | 2000-07-07 | 2007-10-04 | Merck & Co., Inc. | Herstellung eines chimeren papillomavirus |
FI116851B (fi) | 2001-05-03 | 2006-03-15 | Fit Biotech Oyj Plc | Ilmentämisvektori, sen käyttöjä ja menetelmä sen valmistamiseksi sekä sitä sisältäviä tuotteita |
CN1114690C (zh) * | 2001-05-15 | 2003-07-16 | 乔良 | ***瘤假病毒及其制备方法 |
ATE471990T1 (de) | 2001-08-13 | 2010-07-15 | Univ Rochester | Transkutane immunisierung gegen papillomavirus mit virusähnlichen papillomaviruspartikeln |
ITVA20050021A1 (it) | 2005-04-01 | 2006-10-02 | Sergio Biucchi | Dispositivi informatici off-line per il sistema delle transazioni valutarie autogestite |
WO2007064971A2 (en) * | 2005-12-01 | 2007-06-07 | The Government Of The Usa, As Represented By The Secretary, Dept. Of Health & Human Services | Infectious papovavirus particle comprising a cytocidal gene and methods of use thereof |
US8778351B2 (en) | 2006-08-30 | 2014-07-15 | University Of Rochester | Combined human papillomavirus VLP/gene delivery system and use thereof as a vaccine for prophylaxis and immunotherapy of infectious diseases and tumors |
DK2416798T3 (en) * | 2009-04-10 | 2018-01-08 | Univ Johns Hopkins | PAPILLOMAVIRUS-LIKE PARTICLES (VLP) AS WIDE-SPECIFIED VACCINES AGAINST HUMAN PAPILLOMAVIRUS (HPV) |
ES2845212T3 (es) | 2009-04-13 | 2021-07-26 | Inst Nat Sante Rech Med | Partículas de HPV y usos de las mismas |
US20120225090A1 (en) * | 2009-08-03 | 2012-09-06 | The Johns Hopkins University | Methods for enhancing antigen-specific immune responses |
CN107715118A (zh) * | 2009-08-26 | 2018-02-23 | 西莱克塔生物科技公司 | 诱导t细胞辅助的组合物 |
US9700639B2 (en) | 2012-02-07 | 2017-07-11 | Aura Biosciences, Inc. | Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells |
AU2014323424B2 (en) | 2013-09-18 | 2019-12-19 | Aura Biosciences, Inc. | Virus-like particle conjugates for diagnosis and treatment of tumors |
US10066023B2 (en) | 2015-10-30 | 2018-09-04 | Aleta Biotherapeutics Inc. | Compositions and methods for tumor transduction |
EP3368656A4 (de) | 2015-10-30 | 2019-07-17 | The United States of America, as represented by the secretary, Department of Health and Human Services | Gezielte krebstherapie |
EP3368559A4 (de) | 2015-10-30 | 2020-01-15 | Aleta Biotherapeutics Inc. | Zusammensetzungen und verfahren zur behandlung von krebs |
DE102016215500B4 (de) * | 2016-08-18 | 2020-02-20 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Sensorsystem zur Charakterisierung des Zustandes von in einem Kultivierungsgefäß enthaltenen Proben einer heterogenen Biomassestruktur |
JP2021502355A (ja) | 2017-11-06 | 2021-01-28 | ザ・ユナイテッド・ステイツ・オブ・アメリカ・アズ・リプリゼンテッド・バイ・ザ・セクレタリー・デパートメント・オブ・ヘルス・アンド・ヒューマン・サービシーズThe United States of America,as represented by the Secretary,Department of Health and Human Services | 既存の微生物免疫を利用した癌処置 |
CN116350803B (zh) * | 2023-05-19 | 2023-11-24 | 健通(济南)生物科技有限公司 | 一种以***瘤病毒样颗粒为载体的mRNA递药***及制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5437951A (en) | 1992-09-03 | 1995-08-01 | The United States Of America As Represented By The Department Of Health And Human Services | Self-assembling recombinant papillomavirus capsid proteins |
US5618536A (en) * | 1992-09-03 | 1997-04-08 | The United States Of America As Represented By The Department Of Health And Human Services | Chimeric papillomavirus-like particles |
US5792931A (en) * | 1994-08-12 | 1998-08-11 | Pioneer Hi-Bred International, Inc. | Fumonisin detoxification compositions and methods |
CA2202090C (en) * | 1994-10-07 | 2012-04-17 | Lutz Gissmann | Papilloma virus-like particles, fusion proteins as well as processes for their production |
FR2749323B1 (fr) | 1996-06-04 | 1998-07-10 | Pasteur Merieux Serums Vacc | Pseudo-particules virales utiles en tant que vecteur de delivrance d'acide nucleique |
ATE333501T1 (de) * | 1997-09-05 | 2006-08-15 | Medimmune Inc | Methode zur in vitro auseinander- und wiederzusammensetzung von papillomavirus virus- ähnlichen tielchen (vlps) |
-
1997
- 1997-07-14 EP EP97934126A patent/EP0922105B1/de not_active Expired - Lifetime
- 1997-07-14 AT AT97934126T patent/ATE312178T1/de not_active IP Right Cessation
- 1997-07-14 JP JP10506187A patent/JP2000515741A/ja not_active Withdrawn
- 1997-07-14 WO PCT/US1997/012115 patent/WO1998002548A2/en active IP Right Grant
- 1997-07-14 DE DE69734829T patent/DE69734829D1/de not_active Expired - Lifetime
- 1997-07-14 AU AU37256/97A patent/AU732125B2/en not_active Expired
- 1997-07-14 CA CA002257822A patent/CA2257822A1/en not_active Abandoned
- 1997-07-14 US US09/509,748 patent/US6599739B1/en not_active Expired - Lifetime
-
2003
- 2003-05-27 US US10/446,060 patent/US20030207446A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US6599739B1 (en) | 2003-07-29 |
EP0922105B1 (de) | 2005-12-07 |
AU732125B2 (en) | 2001-04-12 |
EP0922105A2 (de) | 1999-06-16 |
ATE312178T1 (de) | 2005-12-15 |
AU3725697A (en) | 1998-02-09 |
WO1998002548A3 (en) | 1998-03-05 |
JP2000515741A (ja) | 2000-11-28 |
WO1998002548A2 (en) | 1998-01-22 |
US20030207446A1 (en) | 2003-11-06 |
CA2257822A1 (en) | 1998-01-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |