DE69728997D1 - METHOD FOR PRODUCING CLEANED DIMERS OF THE BONE-DERIVED FACTOR (BONE-DERIVED FACTOR) - Google Patents

METHOD FOR PRODUCING CLEANED DIMERS OF THE BONE-DERIVED FACTOR (BONE-DERIVED FACTOR)

Info

Publication number
DE69728997D1
DE69728997D1 DE69728997T DE69728997T DE69728997D1 DE 69728997 D1 DE69728997 D1 DE 69728997D1 DE 69728997 T DE69728997 T DE 69728997T DE 69728997 T DE69728997 T DE 69728997T DE 69728997 D1 DE69728997 D1 DE 69728997D1
Authority
DE
Germany
Prior art keywords
bone
derived factor
dimers
producing cleaned
cleaned
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69728997T
Other languages
German (de)
Other versions
DE69728997T3 (en
DE69728997T2 (en
Inventor
Jun Honda
Hidetoshi Andou
Shunjiro Sugimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biopharm Gesellschaft zur Biotechnologischen Entwicklung von Pharmaka mbH
Original Assignee
Biopharm Gesellschaft zur Biotechnologischen Entwicklung von Pharmaka mbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18445882&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69728997(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biopharm Gesellschaft zur Biotechnologischen Entwicklung von Pharmaka mbH filed Critical Biopharm Gesellschaft zur Biotechnologischen Entwicklung von Pharmaka mbH
Publication of DE69728997D1 publication Critical patent/DE69728997D1/en
Application granted granted Critical
Publication of DE69728997T2 publication Critical patent/DE69728997T2/en
Publication of DE69728997T3 publication Critical patent/DE69728997T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69728997T 1996-12-25 1997-12-24 METHOD FOR PRODUCING CLEANED DIMERS OF THE BONE DERIVED FACTOR (BONE-DERIVED FACTOR) Expired - Lifetime DE69728997T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP35581296 1996-12-25
JP35581296 1996-12-25
PCT/JP1997/004784 WO1998029559A1 (en) 1996-12-25 1997-12-24 Process for preparing purified dimer of bone-derived factor

Publications (3)

Publication Number Publication Date
DE69728997D1 true DE69728997D1 (en) 2004-06-09
DE69728997T2 DE69728997T2 (en) 2004-09-02
DE69728997T3 DE69728997T3 (en) 2009-07-09

Family

ID=18445882

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69728997T Expired - Lifetime DE69728997T3 (en) 1996-12-25 1997-12-24 METHOD FOR PRODUCING CLEANED DIMERS OF THE BONE DERIVED FACTOR (BONE-DERIVED FACTOR)

Country Status (21)

Country Link
US (1) US6551801B1 (en)
EP (1) EP0949335B2 (en)
KR (1) KR20000062328A (en)
AP (1) AP9901539A0 (en)
AT (1) ATE266095T1 (en)
AU (1) AU5339598A (en)
BR (1) BR9714183A (en)
CA (1) CA2275464A1 (en)
DE (1) DE69728997T3 (en)
DK (1) DK0949335T4 (en)
EA (1) EA199900596A1 (en)
ES (1) ES2216181T5 (en)
HU (1) HUP0002573A2 (en)
IL (1) IL130641A0 (en)
NO (1) NO993151L (en)
PL (1) PL334303A1 (en)
PT (1) PT949335E (en)
SI (1) SI0949335T2 (en)
TR (1) TR199901479T2 (en)
WO (1) WO1998029559A1 (en)
ZA (1) ZA9711580B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7811793B2 (en) * 1996-12-25 2010-10-12 Biopharma Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Process for preparing purified active monomer of bone-derived factor
US20040019185A1 (en) * 1996-12-25 2004-01-29 Hidetoshi Andou Process for preparing purified active monomer of bone-derived factor
CA2404567A1 (en) * 2000-03-30 2001-10-11 Takeda Chemical Industries, Ltd. Process for producing recombinant protein
EP1578348A4 (en) * 2002-02-08 2011-03-16 Wyeth Llc Formulation comprising bioactive agents and method of using same
EP1542711A4 (en) * 2002-08-13 2009-07-01 Wyeth Corp PEPTIDES AS SOLUBILIZING EXCIPIENTS FOR TRANSFORMING GROWTH FACTOR s PROTEINS
JP4800739B2 (en) * 2005-10-20 2011-10-26 デンカ生研株式会社 Assay medium and assay method
AU2007292253A1 (en) * 2006-09-08 2008-03-13 Wyeth Arginine wash in protein purification using affinity chromatography
AU2007234612B2 (en) 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
US7678764B2 (en) 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
EP2187932B1 (en) 2007-08-07 2015-01-28 DePuy Synthes Products, LLC Protein formulations comprising gdf-5 in aqueous acidic solution
CA2720845A1 (en) * 2008-04-14 2009-10-22 Advanced Technologies And Regenerative Medicine, Llc Liquid buffered gdf-5 formulations
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE231523T1 (en) * 1988-04-08 2003-02-15 Stryker Corp OSTEOGENIC DEVICES
ATE287949T1 (en) * 1992-07-31 2005-02-15 Stryker Corp SOLUBLE COMPLEX OF MORPHOGENIC PROTEINS AND COMPOSITIONS THEREOF
JP3570558B2 (en) * 1993-05-01 2004-09-29 持田製薬株式会社 DNA fragment, vector containing the same, transformant transformed with the vector, and method for producing protein using the vector
US5385887A (en) * 1993-09-10 1995-01-31 Genetics Institute, Inc. Formulations for delivery of osteogenic proteins
US5399677A (en) * 1993-12-07 1995-03-21 Genetics Institute, Inc. Mutants of bone morphogenetic proteins
US5702637A (en) 1995-04-19 1997-12-30 Minnesota Mining And Manufacturing Company Liquid crystal compounds having a chiral fluorinated terminal portion
DE69636728D1 (en) * 1995-04-19 2007-01-04 Bioph Biotech Entw Pharm Gmbh NEW PROTEIN AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
PL334303A1 (en) 2000-02-14
WO1998029559A1 (en) 1998-07-09
SI0949335T1 (en) 2004-10-31
ZA9711580B (en) 1999-09-23
PT949335E (en) 2004-09-30
US6551801B1 (en) 2003-04-22
EA199900596A1 (en) 2000-02-28
DK0949335T3 (en) 2004-08-30
NO993151D0 (en) 1999-06-24
EP0949335B2 (en) 2008-11-19
DK0949335T4 (en) 2009-03-23
ES2216181T5 (en) 2009-03-01
SI0949335T2 (en) 2009-04-30
BR9714183A (en) 2000-02-29
TR199901479T2 (en) 1999-09-21
AP9901539A0 (en) 1999-06-30
DE69728997T3 (en) 2009-07-09
ATE266095T1 (en) 2004-05-15
EP0949335A1 (en) 1999-10-13
EP0949335B1 (en) 2004-05-06
AU5339598A (en) 1998-07-31
NO993151L (en) 1999-06-24
CA2275464A1 (en) 1998-07-09
DE69728997T2 (en) 2004-09-02
EP0949335A4 (en) 2003-01-22
IL130641A0 (en) 2000-06-01
ES2216181T3 (en) 2004-10-16
KR20000062328A (en) 2000-10-25
HUP0002573A2 (en) 2000-12-28

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings