DE69728415D1 - Produkte des keratinocyten-wachstumsfaktors 2 (kgf-2) - Google Patents

Produkte des keratinocyten-wachstumsfaktors 2 (kgf-2)

Info

Publication number
DE69728415D1
DE69728415D1 DE69728415T DE69728415T DE69728415D1 DE 69728415 D1 DE69728415 D1 DE 69728415D1 DE 69728415 T DE69728415 T DE 69728415T DE 69728415 T DE69728415 T DE 69728415T DE 69728415 D1 DE69728415 D1 DE 69728415D1
Authority
DE
Germany
Prior art keywords
kgf
growth factor
keratinocyte growth
products
variants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69728415T
Other languages
English (en)
Other versions
DE69728415T2 (de
Inventor
Owens Narhi
D Osslund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Swedish Orphan Biovitrum AB
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DE69728415D1 publication Critical patent/DE69728415D1/de
Publication of DE69728415T2 publication Critical patent/DE69728415T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69728415T 1996-10-15 1997-10-15 Produkte des keratinocyten-wachstumsfaktors 2 (kgf-2) Expired - Lifetime DE69728415T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US2849396P 1996-10-15 1996-10-15
US28493P 1996-10-15
US3278196P 1996-12-06 1996-12-06
US32781P 1996-12-06
US3304696P 1996-12-11 1996-12-11
US33046P 1996-12-11
PCT/US1997/018607 WO1998016642A1 (en) 1996-10-15 1997-10-15 Keratinocyte growth factor-2 products

Publications (2)

Publication Number Publication Date
DE69728415D1 true DE69728415D1 (de) 2004-05-06
DE69728415T2 DE69728415T2 (de) 2004-08-12

Family

ID=27363281

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69728415T Expired - Lifetime DE69728415T2 (de) 1996-10-15 1997-10-15 Produkte des keratinocyten-wachstumsfaktors 2 (kgf-2)
DE19781038T Withdrawn DE19781038T1 (de) 1996-10-15 1997-10-15 Keratinozytenwachstumsfaktor-2-Produkte

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19781038T Withdrawn DE19781038T1 (de) 1996-10-15 1997-10-15 Keratinozytenwachstumsfaktor-2-Produkte

Country Status (12)

Country Link
EP (1) EP0935652B1 (de)
JP (2) JP2001506975A (de)
AT (1) ATE263239T1 (de)
AU (1) AU727678C (de)
CA (1) CA2269077C (de)
DE (2) DE69728415T2 (de)
DK (1) DK0935652T3 (de)
ES (1) ES2218666T3 (de)
GB (1) GB2322132B (de)
HK (1) HK1022714A1 (de)
PT (1) PT935652E (de)
WO (1) WO1998016642A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6693077B1 (en) 1995-02-14 2004-02-17 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US6077692A (en) 1995-02-14 2000-06-20 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US7232667B2 (en) 1995-02-14 2007-06-19 Human Genome Sciences, Inc. Keratinocyte growth factor-2 polynucleotides
AU739773B2 (en) * 1996-08-13 2001-10-18 Human Genome Sciences, Inc. Keratinocyte growth factor-2 (KGF-2 or fibroblast growth factor-12, FGF-12)
SI0941110T1 (en) * 1996-10-15 2004-06-30 Amgen Inc. Uses of keratinocyte growth factor-2
US6869927B1 (en) 1997-12-22 2005-03-22 Human Genome Sciences, Inc. Keratinocyte growth factor-2 formulations
US6238888B1 (en) 1997-12-22 2001-05-29 Human Genone Sciences, Inc. Keratinocyte growth factor-2 formulations
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
KR20020010920A (ko) * 1999-06-02 2002-02-06 추후제출 각질세포 성장 인자-2 제제
NZ516897A (en) * 1999-07-02 2004-01-30 Human Genome Sciences Inc Polynucleotides and associated polypeptides for KGF-2 (also known as Fibroblast Growth Factor 12) to promote and accelerate internal and external wound healing
JP3966819B2 (ja) * 2001-05-24 2007-08-29 キム，スーギョン 毛嚢に存在する新規の第２ケラチノサイト成長因子類似体
EP1406573A4 (de) * 2001-06-07 2005-03-30 Skinmedica Inc Konditionierte zellkulturmedien und ihre verwendungszwecke

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2166278A1 (en) * 1993-06-29 1995-01-12 Denis J. Gospodarowicz A truncated keratinocyte growth factor (kgf) having increased biological activity
EP0742830B1 (de) * 1994-02-01 2001-07-18 THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services Fusionierte proteine die antikörper-teile und nicht-antikörper-teile enthalten
WO1996011949A2 (en) * 1994-10-13 1996-04-25 Amgen Inc. Analogs of keratinocyte growth factor
ES2196088T3 (es) * 1994-10-13 2003-12-16 Amgen Inc Analogos del factor de crecimiento de los queratinocitos.
EP0815115B1 (de) * 1995-02-14 2003-05-28 Human Genome Sciences, Inc. Keratinozyten-wachstumsfaktor 2
AU739773B2 (en) * 1996-08-13 2001-10-18 Human Genome Sciences, Inc. Keratinocyte growth factor-2 (KGF-2 or fibroblast growth factor-12, FGF-12)

Also Published As

Publication number Publication date
PT935652E (pt) 2004-07-30
DE19781038T1 (de) 1998-12-10
GB2322132A (en) 1998-08-19
JP2001506975A (ja) 2001-05-29
HK1022714A1 (en) 2000-08-18
DE69728415T2 (de) 2004-08-12
AU4757697A (en) 1998-05-11
CA2269077A1 (en) 1998-04-23
EP0935652B1 (de) 2004-03-31
WO1998016642A1 (en) 1998-04-23
AU727678C (en) 2005-05-12
DK0935652T3 (da) 2004-07-26
JP2008283980A (ja) 2008-11-27
EP0935652A1 (de) 1999-08-18
CA2269077C (en) 2004-04-06
GB9811279D0 (en) 1998-07-22
ES2218666T3 (es) 2004-11-16
ATE263239T1 (de) 2004-04-15
AU727678B2 (en) 2000-12-21
GB2322132B (en) 1999-09-22

Similar Documents

Publication Publication Date Title
PT101297A (pt) Factores mitogenicos gliais, sua preparacao e utilizacao
BG102071A (en) Minor molecule inhibitors of rotamase enzymic activity
DE69029657D1 (de) Menschliches cytokin, interleukin-9
IL117425A0 (en) Receptor activation by gas6
DE69942459D1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
RU94046367A (ru) Днк, хозяйская клетка, способ получения белка, белок, фармацевтический препарат, антитело, применение антитела
ATE449850T1 (de) Mutanten von flt3-l und ihre verwendungen
ES2133813T3 (es) Cadenas de lamininas: diagnostico y uso terapeutico.
ATE263239T1 (de) Produkte des keratinocyten-wachstumsfaktors 2 (kgf-2)
DE69726884D1 (de) Menschliches sdf-5 protein und diesbezügliche zusammensetzungen
WO1997026322A3 (en) Methods and compositions for inhibiting hexokinase
DK1082423T3 (da) Cyclin E2-gener og -proteiner
WO1997008934A3 (en) Aryl acrylic acid derivatives useful as protein tyrosine phosphatase inhibitors
DK0977859T3 (da) Den neurotrofiske faktor NNT-1
ES2117717T3 (es) Tratamiento de tumores con factores neurotroficos e inhibidores de la proliferacion celular.
DE69838615D1 (de) ppGpp-SYNTHETASE UND EXPRESSIONSSYSTEME ZUR VERBESSERTEN HERSTELLUNG VON PROTEINEN
ATE338768T1 (de) Muc-1 derivate und deren verwendung zur behandlung von krebsassoziierter muc-1 mucin induzierter immunosuppression
ATE389014T1 (de) Phosphorylierte glyoxalase i und deren verwendung
SE9604439D0 (sv) New receptor
FR2654430B1 (fr) Nouveaux derives de peptides, utilisables comme inhibiteurs des collagenases bacteriennes.
DK143984A (da) Nitrogenkilde til organismer
MXPA04004262A (es) Delta-1-pirrolinas.
WO2000061750A3 (en) TYROSINE KINASE SUBSTRATE (Tks) PROTEINS
AU4210900A (en) Products and methods for treating ptp lar related diseases
MX9804706A (es) Isoindolona fusionada como inhibidores de quinasa c de proteina.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BIOVITRUM AB (PUBL), STOCKHOLM, SE