DE69718052D1 - Menschliches wachstumsgen und minderwuchse gen bereich - Google Patents

Menschliches wachstumsgen und minderwuchse gen bereich

Info

Publication number
DE69718052D1
DE69718052D1 DE69718052T DE69718052T DE69718052D1 DE 69718052 D1 DE69718052 D1 DE 69718052D1 DE 69718052 T DE69718052 T DE 69718052T DE 69718052 T DE69718052 T DE 69718052T DE 69718052 D1 DE69718052 D1 DE 69718052D1
Authority
DE
Germany
Prior art keywords
sequence
shox
given
growth
human growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69718052T
Other languages
English (en)
Other versions
DE69718052T2 (de
Inventor
Gudrun Rappold-Hoerbrand
Ercole Rao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RAPPOLD HOERBRAND GUDRUN
Original Assignee
RAPPOLD HOERBRAND GUDRUN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RAPPOLD HOERBRAND GUDRUN filed Critical RAPPOLD HOERBRAND GUDRUN
Application granted granted Critical
Publication of DE69718052D1 publication Critical patent/DE69718052D1/de
Publication of DE69718052T2 publication Critical patent/DE69718052T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Obesity (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE69718052T 1996-10-01 1997-09-29 Menschliches wachstumsgen und minderwuchse gen bereich Expired - Lifetime DE69718052T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2763396P 1996-10-01 1996-10-01
EP97100583 1997-01-16
PCT/EP1997/005355 WO1998014568A1 (en) 1996-10-01 1997-09-29 Human growth gene and short stature gene region

Publications (2)

Publication Number Publication Date
DE69718052D1 true DE69718052D1 (de) 2003-01-30
DE69718052T2 DE69718052T2 (de) 2003-07-31

Family

ID=26145174

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69718052T Expired - Lifetime DE69718052T2 (de) 1996-10-01 1997-09-29 Menschliches wachstumsgen und minderwuchse gen bereich

Country Status (20)

Country Link
US (2) US7252974B2 (de)
EP (2) EP0946721B1 (de)
JP (2) JP2000515025A (de)
KR (1) KR20000048838A (de)
CN (1) CN1232499A (de)
AT (1) ATE230026T1 (de)
AU (1) AU744188C (de)
BR (1) BR9712185A (de)
CA (2) CA2267097A1 (de)
CZ (1) CZ297640B6 (de)
DE (1) DE69718052T2 (de)
DK (1) DK0946721T3 (de)
ES (1) ES2188992T3 (de)
HU (1) HU225131B1 (de)
IL (1) IL129015A0 (de)
NO (1) NO991554L (de)
NZ (1) NZ334970A (de)
PL (1) PL194248B1 (de)
SI (1) SI0946721T1 (de)
WO (1) WO1998014568A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2368223A1 (en) * 1999-03-19 2000-09-28 Craig A. Rosen 48 human secreted proteins
AU3913100A (en) * 1999-03-26 2000-10-16 Human Genome Sciences, Inc. 50 human secreted proteins
US7927597B2 (en) 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
EP2280030A3 (de) 2001-04-10 2011-06-15 Agensys, Inc. Nukleinsäuren und zugehörige Proteine für die Behandlung und den Nachweis von Krebs
US20040248132A1 (en) 2001-10-04 2004-12-09 Toshiyuki Sakai DR5 gene promoter and siah-1 gene promoter
EP1583554A2 (de) * 2003-01-13 2005-10-12 Gudrun Rappold-Hoerbrand Verwendung eines natriuretischen peptids zur behandlung von mit shox gen verbundenen wachstumsstörungen
BRPI0607508B8 (pt) 2005-04-15 2021-07-27 Epigenomics Ag método para detecção e/ou classificação de distúrbios proliferativos celulares colorretais ou hepatocelulares, e uso do mesmo
US7382944B1 (en) 2006-07-14 2008-06-03 The United States Of America As Represented By The Administration Of The National Aeronautics And Space Administration Protective coating and hyperthermal atomic oxygen texturing of optical fibers used for blood glucose monitoring
DK2258871T3 (da) * 2007-01-19 2014-08-11 Epigenomics Ag Fremgangsmåder og nukleinsyrer til analyse af celleproliferative lidelser
EP2994541A4 (de) * 2013-05-06 2017-01-18 Capilet Genetics AB Diagnosetest für skelettatavismus bei pferden

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445933A1 (de) * 1984-12-17 1986-06-19 Röhm GmbH, 6100 Darmstadt Arzneimittel mit diuretischer wirksamkeit
US4983511A (en) * 1989-01-09 1991-01-08 Olin Corporation Method and kit for detecting live microorganisms in chlorine- or bromine-treated water

Also Published As

Publication number Publication date
HUP9904175A3 (en) 2002-01-28
DK0946721T3 (da) 2003-04-14
DE69718052T2 (de) 2003-07-31
WO1998014568A1 (en) 1998-04-09
ATE230026T1 (de) 2003-01-15
CZ297640B6 (cs) 2007-02-21
EP1260228A3 (de) 2003-03-05
EP0946721A1 (de) 1999-10-06
US7252974B2 (en) 2007-08-07
BR9712185A (pt) 1999-08-31
ES2188992T3 (es) 2003-07-01
US20030059805A1 (en) 2003-03-27
EP1260228A2 (de) 2002-11-27
NO991554D0 (no) 1999-03-30
IL129015A0 (en) 2000-02-17
EP0946721B1 (de) 2002-12-18
US20090111744A1 (en) 2009-04-30
PL194248B1 (pl) 2007-05-31
SI0946721T1 (en) 2003-06-30
AU744188B2 (en) 2002-02-14
NO991554L (no) 1999-05-14
AU4625297A (en) 1998-04-24
CN1232499A (zh) 1999-10-20
AU744188C (en) 2003-07-24
CA2647169A1 (en) 1998-04-09
HU225131B1 (en) 2006-06-28
JP2004201692A (ja) 2004-07-22
JP2000515025A (ja) 2000-11-14
CA2267097A1 (en) 1998-04-09
KR20000048838A (ko) 2000-07-25
CZ96699A3 (cs) 1999-08-11
NZ334970A (en) 2000-12-22
HUP9904175A2 (hu) 2000-04-28
PL332568A1 (en) 1999-09-27

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