DE69715241T2 - Biaryl-pyridochinazolinonderivate als antikrebsmittel - Google Patents

Biaryl-pyridochinazolinonderivate als antikrebsmittel

Info

Publication number
DE69715241T2
DE69715241T2 DE69715241T DE69715241T DE69715241T2 DE 69715241 T2 DE69715241 T2 DE 69715241T2 DE 69715241 T DE69715241 T DE 69715241T DE 69715241 T DE69715241 T DE 69715241T DE 69715241 T2 DE69715241 T2 DE 69715241T2
Authority
DE
Germany
Prior art keywords
alkyl
phenanthrenyl
group
pyridoquinazolinone
biaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69715241T
Other languages
English (en)
Other versions
DE69715241D1 (de
Inventor
Peter Trova
Nan Zhang
Bruce Kitchen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DE69715241D1 publication Critical patent/DE69715241D1/de
Publication of DE69715241T2 publication Critical patent/DE69715241T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69715241T 1996-11-26 1997-11-24 Biaryl-pyridochinazolinonderivate als antikrebsmittel Expired - Fee Related DE69715241T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75686096A 1996-11-26 1996-11-26
PCT/US1997/022501 WO1998023616A1 (en) 1996-11-26 1997-11-24 Biaryl-pyridoquinazolinone derivatives as anti-cancer agents

Publications (2)

Publication Number Publication Date
DE69715241D1 DE69715241D1 (de) 2002-10-10
DE69715241T2 true DE69715241T2 (de) 2003-01-02

Family

ID=25045369

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69715241T Expired - Fee Related DE69715241T2 (de) 1996-11-26 1997-11-24 Biaryl-pyridochinazolinonderivate als antikrebsmittel

Country Status (11)

Country Link
EP (1) EP0944629B1 (de)
JP (1) JP2001507340A (de)
AT (1) ATE223410T1 (de)
AU (1) AU5692298A (de)
CA (1) CA2272916A1 (de)
DE (1) DE69715241T2 (de)
DK (1) DK0944629T3 (de)
ES (1) ES2181053T3 (de)
HK (1) HK1022476A1 (de)
PT (1) PT944629E (de)
WO (1) WO1998023616A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL129825A0 (en) * 1996-11-27 2000-02-29 Pfizer Fused bicyclic pyrimidine derivatives
GB2360280B (en) * 2000-03-06 2004-07-28 Xenova Ltd Heteroaromatic [a] phenazine carboxamides as topoisomerase inhibitors

Also Published As

Publication number Publication date
HK1022476A1 (en) 2000-08-11
JP2001507340A (ja) 2001-06-05
WO1998023616A1 (en) 1998-06-04
ATE223410T1 (de) 2002-09-15
EP0944629A1 (de) 1999-09-29
DK0944629T3 (da) 2002-12-30
ES2181053T3 (es) 2003-02-16
EP0944629B1 (de) 2002-09-04
DE69715241D1 (de) 2002-10-10
PT944629E (pt) 2002-12-31
CA2272916A1 (en) 1998-06-04
AU5692298A (en) 1998-06-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee