DE69713110D1 - 4-aminoethoxy-indolon-derivate - Google Patents

4-aminoethoxy-indolon-derivate

Info

Publication number
DE69713110D1
DE69713110D1 DE69713110T DE69713110T DE69713110D1 DE 69713110 D1 DE69713110 D1 DE 69713110D1 DE 69713110 T DE69713110 T DE 69713110T DE 69713110 T DE69713110 T DE 69713110T DE 69713110 D1 DE69713110 D1 DE 69713110D1
Authority
DE
Germany
Prior art keywords
hydrogen
addiction
dihydro
integers
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69713110T
Other languages
English (en)
Other versions
DE69713110T2 (de
Inventor
Eric Mewshaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of DE69713110D1 publication Critical patent/DE69713110D1/de
Application granted granted Critical
Publication of DE69713110T2 publication Critical patent/DE69713110T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE69713110T 1996-08-27 1997-08-26 4-aminoethoxy-indolon-derivate Expired - Fee Related DE69713110T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70361096A 1996-08-27 1996-08-27
PCT/US1997/014950 WO1998008819A1 (en) 1996-08-27 1997-08-26 4-aminoethoxy indolone derivatives

Publications (2)

Publication Number Publication Date
DE69713110D1 true DE69713110D1 (de) 2002-07-11
DE69713110T2 DE69713110T2 (de) 2002-12-19

Family

ID=24826069

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69713110T Expired - Fee Related DE69713110T2 (de) 1996-08-27 1997-08-26 4-aminoethoxy-indolon-derivate

Country Status (12)

Country Link
EP (1) EP0923551B1 (de)
JP (1) JP2000516959A (de)
KR (1) KR20000035818A (de)
CN (1) CN1234024A (de)
AT (1) ATE218548T1 (de)
AU (1) AU4088897A (de)
CA (1) CA2264078A1 (de)
DE (1) DE69713110T2 (de)
DK (1) DK0923551T3 (de)
ES (1) ES2179362T3 (de)
PT (1) PT923551E (de)
WO (1) WO1998008819A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5990144A (en) * 1997-02-18 1999-11-23 American Home Products Corporation 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists
EP0964853A1 (de) * 1997-02-18 1999-12-22 American Home Products Corporation 4-aminoalkoxy-1,3-dihydrobenzimidazol-2-on derivate, deren herstellung undderen verwendung als dopamin autorezeptor (d2) agonisten
ES2188155T3 (es) * 1998-04-08 2003-06-16 Wyeth Corp N-ariloxietilindolilalquilaminas para el tratamiento de la depresion.
US6150533A (en) * 1998-04-08 2000-11-21 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
US6110956A (en) * 1998-04-08 2000-08-29 American Home Products Corp. N-aryloxyethylamine derivatives for the treatment of depression
ES2182509T3 (es) * 1998-04-08 2003-03-01 Wyeth Corp Derivados de n-ariloxietilamina para el tratamiento de la depresion.
ZA992670B (en) * 1998-04-13 2000-10-12 American Home Prod 4-amino-(ethylamino)-oxindole dopamine autoreceptor agonists.
FR2845992B1 (fr) * 2002-10-16 2005-02-04 Pf Medicament Derives de 3-(cyclopenten-1yl)-benzyl-ou3-(cyclopenten-1yl)- heteroarylmethyl-amines et leur utilisation a titre de medicaments pour le traitement de la schizophrenie
CN113004233B (zh) * 2019-12-18 2022-12-20 南京优氟医药科技有限公司 一种用于制备prc2抑制剂的化合物、其制备方法和用途
CN114507162A (zh) * 2020-11-16 2022-05-17 尚科生物医药（上海）有限公司 一种制备2-氟-5-甲氧基苯磺酰氯的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2210397A2 (en) * 1972-12-20 1974-07-12 Sandoz Sa Aminoalkoxyoxindole derivs - as beta-adren ergic blockers
US4314944A (en) * 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones
FR2510112A1 (fr) * 1981-07-24 1983-01-28 Roussel Uclaf Nouveaux derives du 2-oxo-pyrid-3-yl ou piperidin-3-yl indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
GB8712073D0 (en) * 1987-05-21 1987-06-24 Smith Kline French Lab Medicament
AU4312593A (en) * 1992-05-18 1993-12-13 Smithkline Beecham Plc Use of indolone derivatives for the treatment of memory disorders, sexual dysfunction and Parkinson's disease
MX9304626A (es) * 1992-07-31 1994-02-28 Syntex Inc Derivados heterociclicos utiles en el tratamiento de enfermedades cardiovasculares.

Also Published As

Publication number Publication date
WO1998008819A1 (en) 1998-03-05
AU4088897A (en) 1998-03-19
PT923551E (pt) 2002-09-30
EP0923551A1 (de) 1999-06-23
ATE218548T1 (de) 2002-06-15
EP0923551B1 (de) 2002-06-05
ES2179362T3 (es) 2003-01-16
DK0923551T3 (da) 2002-09-16
KR20000035818A (ko) 2000-06-26
DE69713110T2 (de) 2002-12-19
JP2000516959A (ja) 2000-12-19
CN1234024A (zh) 1999-11-03
CA2264078A1 (en) 1998-03-05

Similar Documents

Publication Publication Date Title
ATE218548T1 (de) 4-aminoethoxy-indolon-derivate
CA2299972A1 (en) Thyromimetic antiobesity agents
NZ332220A (en) Inclusion complexes of aryl-piperazinyl-alkylene-heterocyclic salts (such as ziprasidone) and cyclodextrin
HUP0203971A2 (hu) Imidazoimidazolok és -triazolok mint gyulladásellenes szerek és ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
DE60236719D1 (de) Purinderivate als antagonisten an purinergen rezeptoren
ATE219765T1 (de) Indolderivate als cgmp-pde inhibitoren
GEP20043324B (en) Purine Derivatives
DK0975595T3 (da) Kokainanaloger
RU2003102389A (ru) Замещенные производные хиназолина и их применение в качестве ингибиторов
CA2303577A1 (en) Qt dispersion and heart rate variability improvement with crf antagonists to prevent sudden death
GEP20032958B (en) Adenosine Derivatives
MEP12508A (en) Derivatives of n-/phenyl(piperidine-2-yl) methyl benzamide, preparation method thereof and applications of same in therapeutics
DK0923548T3 (da) 4-Aminoethoxyindoler som dopamin-D2-agonister og som 5HT 1A-ligander
HUP0104657A2 (hu) Imidazolvegyületek és ezeket tartalmazó gyógyászati készítmények
RS111104A (en) 1-/(indol-3-yl)carbonyl/piperazine derivatives
AR037221A1 (es) Compuestos derivados de piridina, uso de los mismos, un procedimiento para su preparacion y un medicamento que contiene uno o mas de dichos compuestos
KR900009605A (ko) 치환된 이미다졸 유도체 및 그들의 제법 및 용도
WO2008071948A3 (en) Aminoalcohol derivatives and their therapeutic use
NZ331742A (en) use of piperazinyl heterocyclic compounds for treating tourette's syndrome
MXPA04005077A (es) Derivados de benzotiazol.
ES2185985T3 (es) Derivados de 4-aminoetoxiindolona como agonistas del receptor d2 de dopamina.
IL126795A0 (en) Pyridyl- and pyrimidyl-piperazines in the treatment of substance abuse disorders
WO2006029075A3 (en) Fibrate compounds having ppar agonist activity
CO5170443A1 (es) Derivados de coclobuten-3,4-diona,su preparacion y su aplicacion terapeutica.
ATE205853T1 (de) Streptograminderivate, ihre herstellung und sie enthaltende pharmazeutische zubereitungen

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: WYETH, MADISON, N.J., US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee