DE69636450D1 - PEPTIDE UND PEPTIDOMIMETIKA MIT STRUKTURELLER ÄHNLICHKEIT MIT p53 UND DIE DIE p53-FUNKTION AKTIVIEREN - Google Patents
PEPTIDE UND PEPTIDOMIMETIKA MIT STRUKTURELLER ÄHNLICHKEIT MIT p53 UND DIE DIE p53-FUNKTION AKTIVIERENInfo
- Publication number
- DE69636450D1 DE69636450D1 DE69636450T DE69636450T DE69636450D1 DE 69636450 D1 DE69636450 D1 DE 69636450D1 DE 69636450 T DE69636450 T DE 69636450T DE 69636450 T DE69636450 T DE 69636450T DE 69636450 D1 DE69636450 D1 DE 69636450D1
- Authority
- DE
- Germany
- Prior art keywords
- peptidomimetics
- peptides
- activate
- function
- structural similarity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Marine Sciences & Fisheries (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Vascular Medicine (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/392,542 US6169073B1 (en) | 1995-02-16 | 1995-02-16 | Peptides and peptidomimetics with structural similarity to human p53 that activate p53 function |
US392542 | 1995-02-16 | ||
PCT/US1996/001535 WO1996025434A1 (en) | 1995-02-16 | 1996-02-16 | PEPTIDES AND PEPTIDOMIMETICS WITH STRUCTURAL SIMILARITY TO HUMAN p53 THAT ACTIVATE p53 FUNCTION |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69636450D1 true DE69636450D1 (de) | 2006-09-28 |
DE69636450T2 DE69636450T2 (de) | 2007-05-03 |
Family
ID=23550993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69636450T Expired - Lifetime DE69636450T2 (de) | 1995-02-16 | 1996-02-16 | PEPTIDE UND PEPTIDOMIMETIKA MIT STRUKTURELLER ÄHNLICHKEIT MIT p53 UND DIE DIE p53-FUNKTION AKTIVIEREN |
Country Status (10)
Country | Link |
---|---|
US (6) | US6169073B1 (de) |
EP (1) | EP0809655B1 (de) |
JP (1) | JP3980055B2 (de) |
KR (1) | KR100598744B1 (de) |
AT (1) | ATE336511T1 (de) |
AU (1) | AU718963B2 (de) |
CA (1) | CA2213229C (de) |
DE (1) | DE69636450T2 (de) |
ES (1) | ES2271950T3 (de) |
WO (1) | WO1996025434A1 (de) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6169073B1 (en) * | 1995-02-16 | 2001-01-02 | Bayer Corporation | Peptides and peptidomimetics with structural similarity to human p53 that activate p53 function |
GB9521544D0 (en) * | 1995-10-20 | 1995-12-20 | Univ Dundee | Activation of P53 protein and therapeutic applications thereof |
WO1998006753A2 (en) * | 1996-08-13 | 1998-02-19 | Trustees Of Princeton University | P53 mutant |
AU7238098A (en) * | 1997-05-15 | 1998-12-08 | Kyowa Hakko Kogyo Co. Ltd. | Peptides having cyclic structures and exerting p53 protein activty-restoring effect on p53 protein mutants |
US6020135A (en) * | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
US6767889B1 (en) * | 1998-11-10 | 2004-07-27 | Temple University Of The Commonwealth System Of Higher Education | Inhibition of angiogenesis by high molecular weight kininogen and peptide analogs thereof |
WO2000064934A1 (en) * | 1999-04-23 | 2000-11-02 | Research Corporation Technologies, Inc. | Therapeutic compositions and methods for treating tumors |
US6994852B1 (en) | 1999-11-12 | 2006-02-07 | Temple University-Of The Commonwealth System Of Higher Education | Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5 |
US20050245451A1 (en) * | 2000-04-05 | 2005-11-03 | Pincus Matthew R | Peptides selectively lethal to malignant and transformed mammalian cells |
GB0011439D0 (en) * | 2000-05-12 | 2000-06-28 | Novartis Res Found | Cancer diagnosis and assays for screening |
US7196242B2 (en) * | 2000-05-16 | 2007-03-27 | The Regents Of The University Of California | Methods for identifying novel therapeutics and diagnostics in the p53 pathway |
US6664230B1 (en) * | 2000-08-24 | 2003-12-16 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
US6989239B2 (en) * | 2001-06-20 | 2006-01-24 | R.E.D. Laboratories, N.V./S.A. | Methods for diagnosis and treatment of chronic immune diseases |
US20050032060A1 (en) * | 2001-08-31 | 2005-02-10 | Shishir Shah | Arrays comprising pre-labeled biological molecules and methods for making and using these arrays |
AU2003205830A1 (en) | 2002-01-23 | 2003-09-02 | Mohamed Raafat El-Gewely | Molecular libraries |
US6916621B2 (en) * | 2002-03-27 | 2005-07-12 | Spectral Genomics, Inc. | Methods for array-based comparitive binding assays |
PL376536A1 (pl) | 2002-08-28 | 2006-01-09 | Immunex Corporation | Kompozycje i sposoby leczenia chorób układu sercowo-naczyniowego |
WO2005002526A2 (en) * | 2003-07-01 | 2005-01-13 | President And Fellows Of Harvard College | Method and compositions for treatment of viral infections |
EP1648935A2 (de) | 2003-07-25 | 2006-04-26 | Amgen Inc. | Antagonisten und agonisten von ldcam und anwendungsverfahren |
US7109852B2 (en) * | 2004-01-28 | 2006-09-19 | Lear Corporation | Vehicle occupancy intruder security system |
WO2005074521A2 (en) * | 2004-01-30 | 2005-08-18 | The Trustees Of Columbia University In The City Of New York | C-TERMINAL p53 PALINDROMIC PEPTIDE THAT INDUCES APOPTOSIS OF CELLS WITH ABERRANT p53 AND USES THEREOF |
WO2007149062A2 (en) | 2005-03-14 | 2007-12-27 | Board Of Regents, The University Of Texas System | Bioactive fus1 peptides and nanoprticle-polypeptide complexes |
KR100749858B1 (ko) * | 2005-08-12 | 2007-08-16 | 연세대학교 산학협력단 | p53 변이체 및 그의 용도 |
WO2008064401A1 (en) * | 2006-11-28 | 2008-06-05 | Alzhyme Pty Ltd | Improved peptide composition |
US7981998B2 (en) | 2006-12-14 | 2011-07-19 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
WO2008076904A1 (en) | 2006-12-14 | 2008-06-26 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
JP5649825B2 (ja) | 2007-01-31 | 2015-01-07 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 安定化させたp53ペプチドおよびその使用法 |
JP4997293B2 (ja) | 2007-02-23 | 2012-08-08 | エイルロン セラピューティクス,インコーポレイテッド | トリアゾール大環状系 |
KR20160061439A (ko) | 2007-03-28 | 2016-05-31 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 스티칭된 폴리펩티드 |
US9539327B2 (en) * | 2007-11-26 | 2017-01-10 | The Research Foundation For The State University Of New York | Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells |
AU2009262199B2 (en) | 2008-06-27 | 2012-08-09 | Amgen Inc. | Ang-2 inhibition to treat multiple sclerosis |
CN102256615A (zh) | 2009-01-14 | 2011-11-23 | 爱勒让治疗公司 | 拟肽大环化合物 |
CA2774973A1 (en) | 2009-09-22 | 2011-03-31 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
US20110150885A1 (en) | 2009-12-11 | 2011-06-23 | Atyr Pharma, Inc. | Aminoacyl trna synthetases for modulating hematopoiesis |
WO2011139714A2 (en) | 2010-04-26 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase |
AU2011248614B2 (en) | 2010-04-27 | 2017-02-16 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases |
WO2011139853A2 (en) | 2010-04-28 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases |
CA2797374C (en) | 2010-04-29 | 2021-02-16 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl trna synthetases |
US9068177B2 (en) | 2010-04-29 | 2015-06-30 | Atyr Pharma, Inc | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases |
EP2563383B1 (de) | 2010-04-29 | 2017-03-01 | Atyr Pharma, Inc. | Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten von valyl-trna-synthetasen |
JP6008841B2 (ja) | 2010-05-03 | 2016-10-19 | エータイアー ファーマ, インコーポレイテッド | メチオニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
CA2797977C (en) | 2010-05-03 | 2019-08-20 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases |
WO2011139986A2 (en) | 2010-05-03 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of arginyl-trna synthetases |
EP2566499B1 (de) | 2010-05-04 | 2017-01-25 | aTyr Pharma, Inc. | Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten aus einem p38-multi-trna-synthetase-komplex |
EP3023496B1 (de) | 2010-05-13 | 2020-07-29 | Sarepta Therapeutics, Inc. | Verbindungen, die die signalaktivität von interleukin-17- und interleukin-23 modulieren |
CA2799197C (en) | 2010-05-14 | 2019-10-29 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases |
CN103118695B (zh) | 2010-07-12 | 2016-08-03 | Atyr医药公司 | 与甘氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现 |
KR102104762B1 (ko) | 2010-08-13 | 2020-04-24 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티도미메틱 거대고리 |
EP2608801B1 (de) | 2010-08-25 | 2019-08-21 | aTyr Pharma, Inc. | Innovative erkennung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen in zusammenhang mit proteinfragmenten von tyrosyl-trna-synthetasen |
KR20140100937A (ko) | 2011-10-18 | 2014-08-18 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티도미메틱 거대고리 |
CN104144695A (zh) | 2012-02-15 | 2014-11-12 | 爱勒让治疗公司 | ***交联的和硫醚交联的拟肽大环化合物 |
CN107216380A (zh) | 2012-02-15 | 2017-09-29 | 爱勒让治疗公司 | 拟肽大环化合物 |
ES2652136T3 (es) | 2012-02-16 | 2018-01-31 | Atyr Pharma, Inc. | Histidil-tRNA sintetasas para tratar enfermedades autoinmunitarias e inflamatorias |
KR20150082307A (ko) | 2012-11-01 | 2015-07-15 | 에일러론 테라퓨틱스 인코포레이티드 | 이치환 아미노산 및 이의 제조 및 사용 방법 |
CN110478481A (zh) | 2013-03-13 | 2019-11-22 | 比奥阿赛斯技术有限公司 | p97片段及其应用 |
CA2920147C (en) | 2013-08-07 | 2022-09-20 | Yeda Research And Development Co. Ltd. | Peptides capable of reactivating p53 mutants |
KR20220147691A (ko) | 2013-08-09 | 2022-11-03 | 알데릭스, 인코포레이티드 | 인산염 수송을 억제하기 위한 화합물 및 방법 |
SG10201902598VA (en) | 2014-09-24 | 2019-04-29 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and formulations thereof |
BR112017005598A2 (pt) | 2014-09-24 | 2017-12-12 | Aileron Therapeutics Inc | macrociclos peptidomiméticos e usos dos mesmos |
EP3294318A4 (de) | 2015-03-20 | 2019-04-03 | Aileron Therapeutics, Inc. | Peptidomimetische makrozyklen und verwendungen davon |
US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
WO2017044633A1 (en) | 2015-09-10 | 2017-03-16 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles as modulators of mcl-1 |
WO2017066454A2 (en) | 2015-10-14 | 2017-04-20 | X-Therma, Inc. | Compositions and methods for reducing ice crystal formation |
WO2017134671A1 (en) | 2016-02-04 | 2017-08-10 | Yeda Research And Development Co. Ltd. | Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant p53 |
US20220162336A1 (en) | 2018-07-22 | 2022-05-26 | Bioasis Technologies, Inc. | Treatment of lymphatic metastases |
US11091522B2 (en) | 2018-07-23 | 2021-08-17 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
WO2020070021A1 (en) | 2018-10-04 | 2020-04-09 | Koninklijke Philips N.V. | Fluid flow detection for ultrasound imaging devices, systems, and methods |
WO2021072056A1 (en) * | 2019-10-08 | 2021-04-15 | Portage Glasgow Limited | P53 peptide disrupters of f0x04:p53 protein binding, variants and conjugates thereof. |
US20210355468A1 (en) | 2020-05-18 | 2021-11-18 | Bioasis Technologies, Inc. | Compositions and methods for treating lewy body dementia |
US20210393787A1 (en) | 2020-06-17 | 2021-12-23 | Bioasis Technologies, Inc. | Compositions and methods for treating frontotemporal dementia |
US20230108717A1 (en) * | 2021-10-05 | 2023-04-06 | The Penn State Research Foundation | Novel methods of creating a protein map and using said map to identify therapeutic targets |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5362623A (en) | 1991-06-14 | 1994-11-08 | The John Hopkins University | Sequence specific DNA binding by p53 |
CA2124595A1 (en) | 1992-09-30 | 1994-04-14 | Hanswalter Zentgraf | Process for detecting p53-specific antibodies |
FR2698367B1 (fr) | 1992-11-02 | 1995-02-17 | Eurobio Lab | Fragments de la protéine p53 et leurs utilisations dans la détection et le suivi d'états pathologiques. |
GB9224784D0 (en) | 1992-11-26 | 1993-01-13 | Univ Dundee | Cellular protein |
WO1995017213A1 (en) | 1993-12-21 | 1995-06-29 | Sloan-Kettering Institute For Cancer Research | P53-based polypeptide fragments, nucleic acid molecules encoding same, and uses thereof |
US6169073B1 (en) * | 1995-02-16 | 2001-01-02 | Bayer Corporation | Peptides and peptidomimetics with structural similarity to human p53 that activate p53 function |
-
1995
- 1995-02-16 US US08/392,542 patent/US6169073B1/en not_active Expired - Lifetime
-
1996
- 1996-02-16 EP EP96905369A patent/EP0809655B1/de not_active Expired - Lifetime
- 1996-02-16 JP JP52499296A patent/JP3980055B2/ja not_active Expired - Lifetime
- 1996-02-16 WO PCT/US1996/001535 patent/WO1996025434A1/en active IP Right Grant
- 1996-02-16 CA CA2213229A patent/CA2213229C/en not_active Expired - Lifetime
- 1996-02-16 AT AT96905369T patent/ATE336511T1/de not_active IP Right Cessation
- 1996-02-16 US US08/894,327 patent/US6245886B1/en not_active Expired - Lifetime
- 1996-02-16 AU AU49150/96A patent/AU718963B2/en not_active Expired
- 1996-02-16 ES ES96905369T patent/ES2271950T3/es not_active Expired - Lifetime
- 1996-02-16 DE DE69636450T patent/DE69636450T2/de not_active Expired - Lifetime
- 1996-02-16 KR KR1019970705680A patent/KR100598744B1/ko not_active IP Right Cessation
-
2000
- 2000-10-10 US US09/685,027 patent/US6420118B1/en not_active Expired - Lifetime
-
2001
- 2001-04-11 US US09/829,922 patent/US6784157B2/en not_active Expired - Lifetime
-
2002
- 2002-06-04 US US10/160,290 patent/US7189801B2/en not_active Expired - Fee Related
-
2007
- 2007-03-09 US US11/684,285 patent/US7666983B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6245886B1 (en) | 2001-06-12 |
US6784157B2 (en) | 2004-08-31 |
ATE336511T1 (de) | 2006-09-15 |
JPH11500311A (ja) | 1999-01-12 |
AU4915096A (en) | 1996-09-04 |
US6169073B1 (en) | 2001-01-02 |
AU718963B2 (en) | 2000-05-04 |
US6420118B1 (en) | 2002-07-16 |
JP3980055B2 (ja) | 2007-09-19 |
ES2271950T3 (es) | 2007-04-16 |
CA2213229C (en) | 2014-10-14 |
DE69636450T2 (de) | 2007-05-03 |
US20070167611A1 (en) | 2007-07-19 |
US20030124557A1 (en) | 2003-07-03 |
CA2213229A1 (en) | 1996-08-22 |
US20030171537A1 (en) | 2003-09-11 |
US7666983B2 (en) | 2010-02-23 |
KR19980702283A (ko) | 1998-07-15 |
KR100598744B1 (ko) | 2006-09-22 |
EP0809655B1 (de) | 2006-08-16 |
WO1996025434A1 (en) | 1996-08-22 |
US7189801B2 (en) | 2007-03-13 |
EP0809655A1 (de) | 1997-12-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69636450D1 (de) | PEPTIDE UND PEPTIDOMIMETIKA MIT STRUKTURELLER ÄHNLICHKEIT MIT p53 UND DIE DIE p53-FUNKTION AKTIVIEREN | |
GR3034332T3 (en) | Protein purification. | |
DK1149905T3 (da) | Fremgangsmåder og præparat til polypeptidteknologi | |
CA2172376A1 (en) | Antibodies to cd40 | |
HUP0000302A2 (hu) | OB fúziós protein készítmények és módszerek | |
TR199901971T2 (xx) | Bir resept�re ba�lanan peptidler ve bile�ikler. | |
WO2000058473A3 (en) | Nucleic acids including open reading frames encoding polypeptides; 'orfx' | |
AU676859B2 (en) | Synthetic peptides, antibodies against them and their use | |
AU5229498A (en) | Mutants of the lag-3 proteins, products for the expression of these mutants and use | |
ATE397062T1 (de) | Chimäre polypeptide, die das fragment b des shigatoxins sowie peptide von therapeutischem interesse enthalten | |
ES2172044T3 (es) | Supresion de la proliferacion de celulas t usando fragmentos peptidicos de proteina basica de mielina. | |
ZA965565B (en) | Novel peptides derived from human heat shock protein 60 for treatment of diabetes, compositions, methods and kits. | |
WO2000053742A3 (en) | Polynucleotides and proteins encoded thereby | |
ATE314474T1 (de) | Klonering von dem gen für das t gondii protein gp 28.5 peptidfragmente aus diesem protein und ihre verwendungen. | |
AU1239997A (en) | Polypeptides corresponding to the amino acid sequences of proteins p57 or p9.5 of Borna disease virus, nucleic acid fragments coding therefore and their use for diagnostic and immunization purposes | |
UA72875C2 (uk) | БІЛКИ, ЯКІ ЗВ'ЯЗУЮТЬСЯ З <font face="Symbol">b</font>-АМІЛОЇДНИМ ПЕПТИДОМ ТА ПОЛІНУКЛЕОТИДИ, ЩО ЇХ КОДУЮТЬ | |
WO1999022005A3 (en) | Heparan sulfate d-glucosaminyl 3-o-sulfotransferases, an uses therefor | |
WO2000061754A3 (en) | Human proteins and polynucleotides encoding them | |
DE68914397D1 (de) | Menschliches Lymphotoxin. | |
WO2000070046A3 (en) | Secreted polypeptides and corresponding polynucleotides | |
WO1999031229A3 (en) | Peptides and nucleic acids derived from eisenia foetida and the use thereof | |
CA2140091A1 (en) | Peptides and antisera for detecting human cyclooxygenase-1 and cyclooxygenase-2 | |
WO2001023561A3 (en) | Novel polynucleotides encoding proteins containing thrombospondin type 1 repeats | |
WO2002014348A3 (en) | Glycoproteins and methods of use thereof | |
WO2001019856A3 (en) | Secreted human proteins, polynucleotides encoding them and methods of using the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |