DE69635993T8 - Gelierte arzneimittel zur oralen verabreichung - Google Patents

Gelierte arzneimittel zur oralen verabreichung Download PDF

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Publication number
DE69635993T8
DE69635993T8 DE69635993T DE69635993T DE69635993T8 DE 69635993 T8 DE69635993 T8 DE 69635993T8 DE 69635993 T DE69635993 T DE 69635993T DE 69635993 T DE69635993 T DE 69635993T DE 69635993 T8 DE69635993 T8 DE 69635993T8
Authority
DE
Germany
Prior art keywords
gelated
medicaments
oral administration
oral
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE69635993T
Other languages
English (en)
Other versions
DE69635993D1 (de
DE69635993T2 (de
Inventor
Hiroshi Ninomiya
Toshio Shimizu
Masatake Dairaku
Takeshi Komagata
Masayo Misawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nichi Iko Pharmaceutical Co Ltd
Original Assignee
TEIKOKUMEDIX Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP00428996A external-priority patent/JP4309481B2/ja
Priority claimed from JP8004288A external-priority patent/JPH09187233A/ja
Application filed by TEIKOKUMEDIX Co Ltd filed Critical TEIKOKUMEDIX Co Ltd
Publication of DE69635993D1 publication Critical patent/DE69635993D1/de
Application granted granted Critical
Publication of DE69635993T2 publication Critical patent/DE69635993T2/de
Publication of DE69635993T8 publication Critical patent/DE69635993T8/de
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015Devices specially adapted for taking medicines
    • A61J7/0046Cups, bottles or bags
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06Ampoules or carpules
    • A61J1/067Flexible ampoules, the contents of which are expelled by squeezing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/02Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0223Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by shape
    • B65D1/023Neck construction
    • B65D1/0238Integral frangible closures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/09Ampoules
    • B65D1/095Ampoules made of flexible material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52Details
    • B65D75/58Opening or contents-removing devices added or incorporated during package manufacture
    • B65D75/5805Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness
    • B65D75/5811Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness and defining, after tearing, a small dispensing spout, a small orifice or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mechanical Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Ceramic Engineering (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69635993T 1996-01-12 1996-07-17 Gelierte arzneimittel zur oralen verabreichung Active DE69635993T8 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP00428996A JP4309481B2 (ja) 1996-01-12 1996-01-12 ゼリー状経口医薬組成物
JP428896 1996-01-12
JP428996 1996-01-12
JP8004288A JPH09187233A (ja) 1996-01-12 1996-01-12 ゼリー組成物
PCT/JP1996/001993 WO1997025024A1 (fr) 1996-01-12 1996-07-17 Composition medicinale gelifiee pour administration orale

Publications (3)

Publication Number Publication Date
DE69635993D1 DE69635993D1 (de) 2006-05-18
DE69635993T2 DE69635993T2 (de) 2007-01-25
DE69635993T8 true DE69635993T8 (de) 2007-10-31

Family

ID=26338035

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69635993T Active DE69635993T8 (de) 1996-01-12 1996-07-17 Gelierte arzneimittel zur oralen verabreichung

Country Status (5)

Country Link
US (1) US5932235A (de)
EP (1) EP0873749B1 (de)
KR (2) KR100764531B1 (de)
DE (1) DE69635993T8 (de)
WO (1) WO1997025024A1 (de)

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US5438075A (en) 1993-03-30 1995-08-01 Skubitz; Keith M. Oral glutamine to reduce stomatitis
US6277395B1 (en) 1998-07-31 2001-08-21 Ryukakusan Co. Ltd. Swallowing-assistive drink
ES2210850T3 (es) * 1998-01-08 2004-07-01 Otsuka Foods Co., Ltd. Alimentos gelificados y procedimiento para su fabricacion.
JP3798913B2 (ja) * 1998-07-31 2006-07-19 伊那食品工業株式会社 増粘用添加液
AU5591499A (en) * 1998-08-07 2000-02-28 Christian Theodore Hattingh Oral pharmaceutical preparation dispenser
WO2000069470A2 (en) * 1999-05-17 2000-11-23 Aesgen, Inc. Improved cellular uptake of bioactive agents
US6461589B2 (en) * 1999-08-27 2002-10-08 Wisconsin Alumni Research Foundation Standardized compositions which facilitate swallowing in dysphagic subjects
US6281177B1 (en) * 2000-02-11 2001-08-28 Masayasu Moriyama Bath jelly and method of using the same
USRE39125E1 (en) * 2000-03-13 2006-06-13 Ryukakusan Co. Ltd Swallowing-assistive drink
EP2260723A3 (de) 2001-08-02 2013-01-02 Simply Thick LLC Verfahren zur Herstellung von Konzentratverdickungsmittelzusammensetzungen
US7638150B2 (en) * 2002-08-02 2009-12-29 Simply Thick Llp Process for preparing concentrate thickener compositions
US20090215735A1 (en) * 2002-02-25 2009-08-27 Alcon, Inc. Topical solution formulations containing a corticosteroid and a cyclodextrin
JP5153045B2 (ja) * 2002-07-29 2013-02-27 帝國製薬株式会社 漢方ゼリー医薬組成物
ES2405287T3 (es) * 2002-08-01 2013-05-30 Eisai Inc. Tratamiento mejorado del cáncer con glutamina
ES2319990T3 (es) * 2003-01-31 2009-05-18 Simply Thick Llc Bebidas espesadas mejoradas para disfagia.
CN100548381C (zh) * 2003-09-12 2009-10-14 株式会社龙角散 能掩盖苦味的粒状凝胶饮料
WO2005099670A1 (en) * 2004-03-31 2005-10-27 Richard Soltero Method for administering medicaments to subjects with swallowing difficulties and disorders
US20080226705A1 (en) * 2004-03-31 2008-09-18 Soltero Richard A Gel delivery system for oral administration of medicaments
US7555329B2 (en) * 2004-06-18 2009-06-30 Department Of Veterans Affairs Method and apparatus for quantifying pharyngeal residue
US9452150B2 (en) * 2004-08-18 2016-09-27 Mochida Pharmaceutical Co., Ltd. Jelly composition
US20070128285A1 (en) * 2005-07-12 2007-06-07 Chikara Jin Pharmaceutical composition for oral administration
WO2007018801A1 (en) * 2005-07-28 2007-02-15 Teikoku Pharma Usa, Inc. Gelled donepezil compositions and methods for making and using the same
EP1946755B1 (de) * 2005-11-11 2017-03-15 Mochida Pharmaceutical Co., Ltd. Gel-zusammensetzung
KR200412734Y1 (ko) * 2006-01-06 2006-03-31 윤상화 식물 영양제용 연질 플라스틱 블로우 가공물의 결합체
TW200744908A (en) * 2006-03-31 2007-12-16 Wyeth Corp A tear and spill resistant package for dispensing liquids in a controlled manner
DE102006015913A1 (de) * 2006-04-05 2007-10-11 Bernd Hansen Sicherheitseinrichtung für mindestens einen Behälter, insbesondere blasgeformten Kunststoffbehälter
US8187659B2 (en) 2006-05-02 2012-05-29 Jerry Robertson Real Estate Llc Solid medicament dosage form consumption aid
WO2008137181A1 (en) * 2007-05-07 2008-11-13 Clearly Superior, Inc Food thickening agent, method for producing food thickening agent
FR2918874B1 (fr) 2007-07-20 2009-10-09 Philippe Perovitch Dispositif de conditionnement et d'administration sub-linguale de principes actifs
US9858831B2 (en) 2009-02-15 2018-01-02 Cheryl L. Evans Method for determining and prescribing quantifiable and customized diet for patient suffering from dysphagia
US8936471B2 (en) 2009-02-15 2015-01-20 Cheryl L. Evans Flow rate measuring device
US8753124B2 (en) * 2009-02-15 2014-06-17 Cheryl Lynn Evans Method and apparatus for prescribing and preparing a reproducible and customized dysphagia diet
US9050357B2 (en) * 2010-03-08 2015-06-09 Cp Kelco U.S., Inc. Compositions and methods for producing consumables for patients with dysphagia
US8383135B2 (en) 2010-12-03 2013-02-26 Richard C. Fuisz Solid dosage form that promotes reliable oral, esophageal and GI transit
US20120294893A1 (en) * 2011-05-20 2012-11-22 Nitto Denko Corporation Edible jelly-form composition, jelly-form preparation and method for producing jelly-form preparation
JP5763994B2 (ja) 2011-07-13 2015-08-12 日東電工株式会社 ゼリー状製剤及びゼリー状製剤の製造方法
EP2827839B1 (de) 2012-03-20 2019-02-27 Particle Dynamics International, LLC Dosierungsform auf basis eines gelierungsmittels
US10568831B2 (en) 2012-06-29 2020-02-25 Wisconsin Alumni Research Foundation Method to enhance swallowing safety and appeal of beverages for treating dysphagia based on rheological and sensory parameters
CN103171824A (zh) * 2012-12-17 2013-06-26 李红彪 一种包装容器
US9101156B2 (en) 2013-03-15 2015-08-11 Kent Precision Foods Group, Inc. Thickener composition, thickened nutritive products, methods for preparing thickened nutritive products, and methods for providing nutrition
CA2950721C (en) 2014-08-08 2020-05-12 Nichi-Iko Pharmaceutical Co.,Ltd. Jelly-like medicinal composition of potassium iodide
US9629489B2 (en) 2015-07-20 2017-04-25 Jsip, Llc Passing a blob from a container into a mouth
US11286096B2 (en) * 2016-03-30 2022-03-29 Pouch Pac Innovations, Llc Opening mechanism for plastic vial
KR20170133575A (ko) * 2016-05-25 2017-12-06 주식회사 코아팜바이오 신규 반고형 제제
KR20190043369A (ko) * 2017-10-18 2019-04-26 주식회사 코아팜바이오 유데나필의 신규한 반고형 제제
US11751594B2 (en) 2020-10-22 2023-09-12 Grain Processing Corporation Food thickener composition and method
KR20220096718A (ko) 2020-12-31 2022-07-07 주식회사 제뉴원사이언스 도네페질 또는 이의 약학적으로 허용되는 염을 포함하는 도네페질 젤리 제제
KR102530365B1 (ko) 2020-12-31 2023-05-10 주식회사 제뉴원사이언스 아세트아미노펜 젤리 제제
WO2023091358A1 (en) * 2021-11-16 2023-05-25 Merck Sharp & Dohme Llc Ampoule for oral vaccine administration and methods of use

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DE88056T1 (de) * 1982-02-08 1984-03-01 Astra Laekemedel Ab, 15185 Soedertaelje Mit normaldosis gefuellter behaelter.
SE8705136D0 (sv) * 1987-12-22 1987-12-22 Pharmacia Ab Oral doseringsenhet for lekemedel och dess anvendning och framstellning
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US5558880A (en) * 1989-12-22 1996-09-24 Janssen Pharmaceutica Inc. Pharmaceutical and other dosage forms
GB9226392D0 (en) * 1992-12-18 1993-02-10 Cpc International Inc Gelling agent
JP2711211B2 (ja) * 1993-09-10 1998-02-10 ベントレップ・サンテ株式会社 吸引服用式薬剤

Also Published As

Publication number Publication date
WO1997025024A1 (fr) 1997-07-17
DE69635993D1 (de) 2006-05-18
EP0873749B1 (de) 2006-03-29
US5932235A (en) 1999-08-03
KR20060011989A (ko) 2006-02-06
KR100611516B1 (ko) 2007-04-25
KR100764531B1 (ko) 2007-10-09
KR19990077144A (ko) 1999-10-25
DE69635993T2 (de) 2007-01-25
EP0873749A4 (de) 2002-04-24
EP0873749A1 (de) 1998-10-28

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: TEIKOKUMEDIX CO., LTD., SAITAMA, JP

8364 No opposition during term of opposition
8381 Inventor (new situation)

Inventor name: NINOMIYA, HIROSHI, SAITAMA, JP

Inventor name: SHIMIZU, TOSHIO, TOKYO, JP

Inventor name: DAIRAKU, MASATAKE, SAITAMA, JP

Inventor name: KOMAGATA, TAKESHI, TOKYO, JP

Inventor name: MISAWA, MASAYO, SAITAMA, JP

8327 Change in the person/name/address of the patent owner

Owner name: NICHI-IKO PHARMA FACTORY CO., LTD., TOYAMA, JP

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