DE69622728D1 - Toxoplasma gondii glykokonjugate - Google Patents

Toxoplasma gondii glykokonjugate

Info

Publication number: DE69622728D1
Authority: DE; Germany
Prior art keywords: gondii; moiety; antibodies; glycoconjugates; preferred
Prior art date: 1995-09-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69622728T

Other languages

English (en)

Inventor

Josephus Koolen

Bas Damm

Boris Striepen

T Schwarz

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Biomerieux BV

Original Assignee

Organon Teknika BV

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-15

Filing date

1996-09-12

Publication date

2002-09-05

1996-09-12 Application filed by Organon Teknika BV filed Critical Organon Teknika BV

2002-09-05 Application granted granted Critical

2002-09-05 Publication of DE69622728D1 publication Critical patent/DE69622728D1/de

2016-09-13 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

241000223997 Toxoplasma gondii Species 0.000 title abstract 9
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
239000003153 chemical reaction reagent Substances 0.000 abstract 2
125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
150000002772 monosaccharides Chemical group 0.000 abstract 2
SUHOOTKUPISOBE-UHFFFAOYSA-N O-phosphoethanolamine Chemical compound NCCOP(O)(O)=O SUHOOTKUPISOBE-UHFFFAOYSA-N 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
230000002238 attenuated effect Effects 0.000 abstract 1
230000008878 coupling Effects 0.000 abstract 1
238000010168 coupling process Methods 0.000 abstract 1
238000005859 coupling reaction Methods 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
125000000524 functional group Chemical group 0.000 abstract 1
150000004676 glycans Chemical group 0.000 abstract 1
125000000625 hexosyl group Chemical group 0.000 abstract 1
230000000984 immunochemical effect Effects 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical group O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 abstract 1
239000012528 membrane Substances 0.000 abstract 1
244000045947 parasite Species 0.000 abstract 1
150000003905 phosphatidylinositols Chemical class 0.000 abstract 1
230000010076 replication Effects 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
229960005486 vaccine Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Tropical Medicine & Parasitology (AREA)
Animal Behavior & Ethology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Microbiology (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE69622728T 1995-09-15 1996-09-12 Toxoplasma gondii glykokonjugate Expired - Lifetime DE69622728D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP95202500		1995-09-15
PCT/EP1996/004034 WO1997010249A1 (en)	1995-09-15	1996-09-12	Toxoplasma gondii glycoconjugates

Publications (1)

Publication Number	Publication Date
DE69622728D1 true DE69622728D1 (de)	2002-09-05

Family

ID=8220639

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69622728T Expired - Lifetime DE69622728D1 (de)	1995-09-15	1996-09-12	Toxoplasma gondii glykokonjugate

Country Status (9)

Country	Link
US (1)	US20020058288A1 (de)
EP (1)	EP0850244B1 (de)
JP (1)	JP2000502244A (de)
KR (1)	KR19990044645A (de)
AT (1)	ATE221539T1 (de)
AU (1)	AU714841B2 (de)
CA (1)	CA2232012A1 (de)
DE (1)	DE69622728D1 (de)
WO (1)	WO1997010249A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8301395L (sv) *	1983-03-15	1984-09-16	Wallac Oy	Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler
AUPP589398A0 (en) *	1998-09-14	1998-10-08	Walter And Eliza Hall Institute Of Medical Research, The	Immunogenic compositions and uses thereof
CN1681529B (zh)	2002-07-26	2012-09-19	沃尔特及伊莱萨霍尔医学研究院	免疫组合物及其诊断和治疗用途
US20070099823A1 (en) *	2005-10-28	2007-05-03	Board Of Trustees Of The University Of Arkansas	Inhibitors of sporeforming pathogens and applications of the same
EP2690104A1 (de)	2012-07-24	2014-01-29	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.	Synthese unterschiedlicher Glycosylphosphatidylinositol-Glycane aus Toxoplasma gondii und deren Verwendung als Impfstoffe und Diagnosemittel
EP2690438A1 (de) *	2012-07-24	2014-01-29	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.	Synthese unterschiedlicher Glycosylphosphatidylinositol-Glycane und -Glycolipide aus Toxoplasma gondii und deren Verwendung als diagnostische Marker und Impfstoffe

1996
- 1996-09-12 AT AT96931804T patent/ATE221539T1/de not_active IP Right Cessation
- 1996-09-12 WO PCT/EP1996/004034 patent/WO1997010249A1/en not_active Application Discontinuation
- 1996-09-12 DE DE69622728T patent/DE69622728D1/de not_active Expired - Lifetime
- 1996-09-12 AU AU70852/96A patent/AU714841B2/en not_active Ceased
- 1996-09-12 JP JP9511671A patent/JP2000502244A/ja active Pending
- 1996-09-12 EP EP96931804A patent/EP0850244B1/de not_active Expired - Lifetime
- 1996-09-12 US US09/043,255 patent/US20020058288A1/en not_active Abandoned
- 1996-09-12 KR KR1019980701899A patent/KR19990044645A/ko not_active Application Discontinuation
- 1996-09-12 CA CA002232012A patent/CA2232012A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO1997010249A1 (en)	1997-03-20
AU7085296A (en)	1997-04-01
KR19990044645A (ko)	1999-06-25
EP0850244B1 (de)	2002-07-31
CA2232012A1 (en)	1997-03-20
ATE221539T1 (de)	2002-08-15
AU714841B2 (en)	2000-01-13
JP2000502244A (ja)	2000-02-29
EP0850244A1 (de)	1998-07-01
US20020058288A1 (en)	2002-05-16

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Legal Events

Date	Code	Title	Description
2003-03-27	8332	No legal effect for de