DE69621459D1 - Reagens und verfahren zur differentiellen bestimmung von leukozyten im blut - Google Patents
Reagens und verfahren zur differentiellen bestimmung von leukozyten im blutInfo
- Publication number
- DE69621459D1 DE69621459D1 DE69621459T DE69621459T DE69621459D1 DE 69621459 D1 DE69621459 D1 DE 69621459D1 DE 69621459 T DE69621459 T DE 69621459T DE 69621459 T DE69621459 T DE 69621459T DE 69621459 D1 DE69621459 D1 DE 69621459D1
- Authority
- DE
- Germany
- Prior art keywords
- leucocytes
- reagents
- blood
- differential determination
- differential
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/573,768 US5817518A (en) | 1995-12-18 | 1995-12-18 | Reagent and method for differential determination of leukocytes in blood |
PCT/US1996/019560 WO1997022878A2 (en) | 1995-12-18 | 1996-12-12 | Reagent and method for differential determination of leukocytes in blood |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69621459D1 true DE69621459D1 (de) | 2002-07-04 |
DE69621459T2 DE69621459T2 (de) | 2003-01-09 |
Family
ID=24293323
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69621459T Expired - Fee Related DE69621459T2 (de) | 1995-12-18 | 1996-12-12 | Reagens und verfahren zur differentiellen bestimmung von leukozyten im blut |
Country Status (5)
Country | Link |
---|---|
US (1) | US5817518A (de) |
EP (1) | EP0874988B1 (de) |
JP (1) | JP3717939B2 (de) |
DE (1) | DE69621459T2 (de) |
WO (1) | WO1997022878A2 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6509192B1 (en) * | 1992-02-24 | 2003-01-21 | Coulter International Corp. | Quality control method |
US5843608A (en) * | 1995-06-08 | 1998-12-01 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
US5830701A (en) * | 1997-03-28 | 1998-11-03 | Tao Medical Electronics Co., Ltd. | Method of detecting hematopoietic progenitor cells |
US6210969B1 (en) | 1999-04-28 | 2001-04-03 | Coulter International Corp. | Composition and method for differentiation of basophil and eosinophil subpopulations of leukocytes in blood |
US6214625B1 (en) | 1999-04-28 | 2001-04-10 | Coulter International Corp. | Composition and method for differentiation of basophils and eosinophils in blood |
JP2005506525A (ja) | 2001-07-27 | 2005-03-03 | ベックマン コールター,インコーポレーテッド | 有核赤血球の計測法の方法 |
US6472215B1 (en) * | 2001-07-27 | 2002-10-29 | Coulter International Corp. | Method of analyzing nucleated red blood cells in a blood sample |
US6573102B2 (en) * | 2001-07-27 | 2003-06-03 | Coulter International Corp. | Lytic reagent composition for determination of nucleated blood cells |
CA2447586A1 (en) * | 2002-11-01 | 2004-05-01 | Streck Laboratories, Inc. | Improved hematology reagent and methods |
US6869798B2 (en) * | 2003-04-17 | 2005-03-22 | Clinical Diagnostics Solutions, Inc. | Lytic reagent composition for leukocyte differential analysis |
US7090882B2 (en) | 2003-06-12 | 2006-08-15 | Cargill, Incorporated | Antimicrobial salt solutions for food safety applications |
US7883732B2 (en) | 2003-06-12 | 2011-02-08 | Cargill, Incorporated | Antimicrobial salt solutions for cheese processing applications |
US7658959B2 (en) | 2003-06-12 | 2010-02-09 | Cargill, Incorporated | Antimicrobial salt solutions for food safety applications |
US7588696B2 (en) | 2003-06-12 | 2009-09-15 | Cargill, Incorporated | Antimicrobial water softener salt and solutions |
EP1500932A1 (de) * | 2003-07-21 | 2005-01-26 | Michael J. Sommer | Lysereagenz zur Analyse residualer wei er Blutkörperchen in leukozytenreduzierten Blutbankprodukte, geeignet zur Anwendung in einem automatischen, klinischen Analysegerät |
US8486472B2 (en) | 2006-01-18 | 2013-07-16 | Cargill, Incorporated | Antimicrobial salt solutions for food safety applications |
CN101078720B (zh) * | 2006-05-22 | 2010-12-01 | 深圳迈瑞生物医疗电子股份有限公司 | 一种改进的用于对白细胞进行分类的试剂及方法 |
CN101078721B (zh) * | 2006-05-23 | 2010-12-22 | 深圳迈瑞生物医疗电子股份有限公司 | 对白细胞进行分类的试剂及方法 |
JP5156738B2 (ja) | 2006-06-06 | 2013-03-06 | エフ.ホフマン−ラ ロシュ アーゲー | 全血試料の特異的溶血 |
ATE452336T1 (de) | 2006-06-06 | 2010-01-15 | Hoffmann La Roche | Gebrauchsfertiges sammelgefäss für vollblut |
US7449337B2 (en) * | 2007-01-24 | 2008-11-11 | Idexx Laboratories, Inc. | Lytic reagent and method for leukocytes differential in whole blood |
WO2008092272A1 (en) * | 2007-02-02 | 2008-08-07 | Canadian Blood Services | Method of detecting bacterial contamination using dynamic light scattering |
CN101349644B (zh) | 2007-07-20 | 2012-06-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种白细胞分类试剂和其使用方法 |
US8102161B2 (en) * | 2007-09-25 | 2012-01-24 | Tdk Corporation | Stable output in a switching power supply by smoothing the output of the secondary coil |
CN105440725A (zh) | 2008-01-04 | 2016-03-30 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类荧光染料,组合物及在生物样品染色中的用途 |
EP2280278A4 (de) * | 2008-05-09 | 2015-04-08 | Sysmex Corp | Blutanalysator, blutanalyseverfahren und hämolytikum |
CN101602762B (zh) | 2008-06-10 | 2013-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类化合物、其制备方法及应用 |
CN101726579B (zh) | 2008-10-17 | 2014-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 血液检测试剂和方法 |
US8367358B2 (en) | 2008-12-17 | 2013-02-05 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Reagent, kit and method for differentiating and counting leukocytes |
CN101988082B (zh) | 2009-07-31 | 2015-04-08 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法 |
WO2011143044A2 (en) * | 2010-05-10 | 2011-11-17 | Idexx Laboratories, Inc. | A lytic reagent system for flow cytometric analysis of leukocytes based on morphology or immunophenotypes |
US9091677B2 (en) | 2010-08-09 | 2015-07-28 | Beckman Coulter, Inc. | Isotonic buffered composition and method that enables counting of cells |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2656508A (en) * | 1949-08-27 | 1953-10-20 | Wallace H Coulter | Means for counting particles suspended in a fluid |
US4298836A (en) * | 1979-11-23 | 1981-11-03 | Coulter Electronics, Inc. | Particle shape determination |
DE3004611A1 (de) * | 1980-02-08 | 1981-08-13 | Hoechst Ag, 6000 Frankfurt | Hochkonzentrierte fuellstoffslurries |
US4485175A (en) * | 1983-01-03 | 1984-11-27 | Coulter Electronics, Inc. | Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes |
US4751179A (en) * | 1984-05-31 | 1988-06-14 | Coulter Electronics, Inc. | Method and reagents for differential determination of four populations of leukocytes in blood |
US5155044A (en) * | 1987-03-13 | 1992-10-13 | Coulter Electronics, Inc. | Lysing reagent system for isolation, identification and/or analysis of leukocytes from whole blood samples |
KR970007077B1 (ko) * | 1987-03-13 | 1997-05-02 | 코울터 일렉트로닉스 인커퍼레이티드 | 광산란 기술을 이용한 다중-부분식별 분석 방법 |
US5389549A (en) * | 1987-05-29 | 1995-02-14 | Toa Medical Electronics Co., Ltd. | Method for classifying leukocytes and a reagent used therefor |
JP2619900B2 (ja) * | 1988-01-27 | 1997-06-11 | 東亜医用電子株式会社 | 血液中の白血球およびヘモグロビンの測定用試薬および方法 |
CA2016699C (en) * | 1989-05-15 | 2003-11-18 | Paul N. Marshall | Lytic agents and uses thereof |
FR2654744B1 (fr) * | 1989-11-20 | 1992-03-13 | Abx Sa | Reactif et methode d'utilisation de celui-ci pour la determination automatique en cytometrie de flux d'au moins une sous-population leucocytaire a partir du sang total. |
FR2658300B1 (fr) * | 1990-02-13 | 1992-05-29 | Abx Sa | Reactif et methode d'utilisation de celui-ci pour la numeration automatique des leucocytes basophiles du sang en appareils de mesure par variation de resistivite. |
DE69327775T2 (de) * | 1992-11-19 | 2000-06-21 | Sysmex Corp., Kobe | Verfahren zur Vorbehandlung für Blutanalyse |
JP3467310B2 (ja) * | 1994-04-21 | 2003-11-17 | シスメックス株式会社 | 白血球分析用試薬及び白血球の分類方法 |
US5639630A (en) * | 1995-05-16 | 1997-06-17 | Bayer Corporation | Method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples, based on intrinsic peroxidase activity of leukocytes |
FR2735579B1 (fr) * | 1995-06-13 | 1997-09-19 | Hycel Groupe Lisabio | Procede de discrimination et d'isolement de sous-populations de leucocytes a partir d'echantillons sanguins par traitement par du polyoxyethylene 9-lauryl ether, et reactif pour sa mise en oeuvre |
-
1995
- 1995-12-18 US US08/573,768 patent/US5817518A/en not_active Expired - Fee Related
-
1996
- 1996-12-12 EP EP96942159A patent/EP0874988B1/de not_active Expired - Lifetime
- 1996-12-12 WO PCT/US1996/019560 patent/WO1997022878A2/en active IP Right Grant
- 1996-12-12 DE DE69621459T patent/DE69621459T2/de not_active Expired - Fee Related
- 1996-12-12 JP JP52286797A patent/JP3717939B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0874988A2 (de) | 1998-11-04 |
JP3717939B2 (ja) | 2005-11-16 |
WO1997022878A3 (en) | 1997-07-24 |
WO1997022878A2 (en) | 1997-06-26 |
US5817518A (en) | 1998-10-06 |
JP2000502187A (ja) | 2000-02-22 |
WO1997022878A8 (en) | 2002-10-10 |
DE69621459T2 (de) | 2003-01-09 |
EP0874988B1 (de) | 2002-05-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |