DE69621229D1 - Antivirale triazazyklododecane - Google Patents

Antivirale triazazyklododecane

Info

Publication number
DE69621229D1
DE69621229D1 DE69621229T DE69621229T DE69621229D1 DE 69621229 D1 DE69621229 D1 DE 69621229D1 DE 69621229 T DE69621229 T DE 69621229T DE 69621229 T DE69621229 T DE 69621229T DE 69621229 D1 DE69621229 D1 DE 69621229D1
Authority
DE
Germany
Prior art keywords
group
aromatic
independently
formula
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69621229T
Other languages
English (en)
Inventor
W Bell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Original Assignee
Research Foundation of State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of State University of New York filed Critical Research Foundation of State University of New York
Application granted granted Critical
Publication of DE69621229D1 publication Critical patent/DE69621229D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69621229T 1995-02-17 1996-02-16 Antivirale triazazyklododecane Expired - Lifetime DE69621229D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/392,550 US5663161A (en) 1995-02-17 1995-02-17 Anti-viral triaza compounds
PCT/US1996/002132 WO1996025167A1 (en) 1995-02-17 1996-02-16 Anti-viral triaza compounds

Publications (1)

Publication Number Publication Date
DE69621229D1 true DE69621229D1 (de) 2002-06-20

Family

ID=23551026

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69621229T Expired - Lifetime DE69621229D1 (de) 1995-02-17 1996-02-16 Antivirale triazazyklododecane

Country Status (10)

Country Link
US (3) US5663161A (de)
EP (1) EP0809504B1 (de)
JP (1) JPH11500130A (de)
CN (1) CN1181013A (de)
AT (1) ATE217529T1 (de)
AU (1) AU701783B2 (de)
CA (1) CA2211920A1 (de)
DE (1) DE69621229D1 (de)
MX (1) MX9706259A (de)
WO (1) WO1996025167A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874573A (en) 1995-06-26 1999-02-23 Concat, Inc. Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
US20050049242A1 (en) * 2000-12-21 2005-03-03 W. Edward Robinson Novel HIV integrase inhibitors and HIV therapy based on drug combinations including integrase inhibitors
AU2002303293A1 (en) * 2001-04-06 2002-10-21 University And Community College System Of Nevada On Behalf Of The University Of Nevada, Reno Triaza compound immunoregulatory agents
US6699465B2 (en) 2001-05-18 2004-03-02 Albany Medical College Covalent attachment of polymer to cell to prevent virus bonding to receptor
CN1656237A (zh) * 2002-04-22 2005-08-17 马里兰大学,巴尔的摩县 衣壳蛋白的抗病毒抑制
WO2006019955A2 (en) * 2004-07-14 2006-02-23 President And Fellows Of Harvard College Antiviral methods and compositions
US20110003393A1 (en) * 2007-10-25 2011-01-06 President And Fellows Of Harvard College Systems and methods for studying influenza
JP6421652B2 (ja) * 2015-03-06 2018-11-14 横浜ゴム株式会社 空気入りタイヤ
GB2539881B (en) * 2015-06-24 2018-07-25 Advanced Risc Mach Ltd An apparatus and method for processing floating point values
JP2021518337A (ja) * 2018-03-16 2021-08-02 ケザール ライフ サイエンシズＫｅｚａｒ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ トリアザシクロドデカンスルホンアミド（「ｔｃｄ」）ベースのタンパク質分泌阻害剤
CN112513065A (zh) 2018-03-29 2021-03-16 科智生命科学公司 Cdp蛋白分泌抑制剂

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001212A (en) * 1973-10-03 1977-01-04 E. I. Du Pont De Nemours And Company Macrocyclic polyamines
US5316757A (en) * 1984-10-18 1994-05-31 Board Of Regents, The University Of Texas System Synthesis of polyazamacrocycles with more than one type of side-chain chelating groups
US4994560A (en) * 1987-06-24 1991-02-19 The Dow Chemical Company Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies
GB8719041D0 (en) * 1987-08-12 1987-09-16 Parker D Conjugate compounds
US5021409A (en) * 1989-12-21 1991-06-04 Johnson Matthey Plc Antiviral cyclic polyamines
WO1991010669A1 (en) * 1990-01-19 1991-07-25 Cockbain, Julian, Roderick, Michaelson Chelating compounds
GB9126677D0 (en) * 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
JPH0827129A (ja) 1994-07-18 1996-01-30 Rikagaku Kenkyusho 環状ポリアミン化合物及びそれを有効成分とする抗ウィルス剤

Also Published As

Publication number Publication date
EP0809504A1 (de) 1997-12-03
AU5170496A (en) 1996-09-04
ATE217529T1 (de) 2002-06-15
EP0809504B1 (de) 2002-05-15
CA2211920A1 (en) 1996-08-22
US6342492B1 (en) 2002-01-29
WO1996025167A1 (en) 1996-08-22
US5663161A (en) 1997-09-02
MX9706259A (es) 1997-11-29
JPH11500130A (ja) 1999-01-06
EP0809504A4 (de) 1998-11-04
CN1181013A (zh) 1998-05-06
AU701783B2 (en) 1999-02-04
US20020019423A1 (en) 2002-02-14

Similar Documents

Publication Publication Date Title
ATE242260T1 (de) Sulfonatfreie cyaninfarbstoffe zur markierung von nukleosiden und nukleotiden
ATE217529T1 (de) Antivirale triazazyklododecane
FI102965B1 (fi) Kondensoituneet heterosykliset yhdisteet, niiden valmistus ja käyttö
IL110091A (en) POLYSUBSTITUTED IMIDAZO £4, 5-c| PYRIDIN-4-AMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FI955438A0 (fi) N-asyylisulfamidihappoesterit (tai -tioesterit), N-asyylisulfonamidit ja N-sulfonyylikarbamiinihappoesterit (tai -tioesterit) hyperkolesteroleemisina aineina
ATE246676T1 (de) Tetrahydrochinolinderivate mit selektive aktivität für retinoid x rezeptoren
KR880013937A (ko) 옥세타노신 유도체
DE69200394T2 (de) 3-Sulfonylamino-2-(1H)-Chinolinone und deren 7-Azaderivate als anregende Aminosäuren Antagonisten.
ES2000908A6 (es) Procedimiento para la fabricacion de nuevos derivados de alquilmercaptofenil-1,3,4-oxadiazol
ATE232732T1 (de) 2',5'-phosphorthioat/phosphodiester- oligoadenylate und ihre antiviralen verwendungen
DE69625795T2 (de) Thiazolidinedionderivate mit antidiabetischen, hypolipidämischen und antihypertensiven Eigenschaften, Verfahren zu deren Herstellung und pharmazeutischen Zusammenstellungen, die sie enthalten
DK0904270T3 (da) Dihydrobenzofuran og beslægtede forbindelser anvendelige som antiinflammatoriske midler
DE69319349D1 (de) Verwendung von aminen in ölzusammensetzungen
ES2170802T3 (es) Carboxamidas biciclicas como ligandos de los receptores 5-ht1a.
GB2341862A (en) Histamine H3 receptor ligands
BR9405907A (pt) Heterociclos de nitrogenio substituídos e seu uso como praguicidas
DE69810294D1 (de) Calixaren-röhren als kationenrezeptoren
DE69709747D1 (de) Polyglycidylether von sekundären alkoholen
TH18165EX (th) สารยับยั้งการเกิดคีโมแทกซิของอีโอซีโนฟีล
TH3875A (th) สารฆ่าวัชพืช n-(ฟอสฟอโนเมธิลไกลซิล) ซัลฟอนิแลมีน
ES8702877A1 (es) Un metodo para producir un derivado de acido benzoico.
TH22634A (th) " เบนซอกซาโซลิล และเบนโซไธอะโซลิลออกซาโซลิดิโนน "
TH18165A (th) สารยับยั้งการเกิดคีโมแทกซิของอีโอซีโนฟีล
TH5423EX (th) อัลฟา-เมทธิลซัลโนนิล-เบนซาลดอกซีมคาร์บาเมท
TH3875EX (th) สารฆ่าวัชพืช n-(ฟอสฟอโนเมธิลไกลซิล) ซัลฟอนิแลมีน

Legal Events

Date Code Title Description
8332 No legal effect for de