DE69600924D1 - Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen - Google Patents

Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen

Info

Publication number
DE69600924D1
DE69600924D1 DE69600924T DE69600924T DE69600924D1 DE 69600924 D1 DE69600924 D1 DE 69600924D1 DE 69600924 T DE69600924 T DE 69600924T DE 69600924 T DE69600924 T DE 69600924T DE 69600924 D1 DE69600924 D1 DE 69600924D1
Authority
DE
Germany
Prior art keywords
container
magnetic particles
magnetic
test medium
magnet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69600924T
Other languages
English (en)
Other versions
DE69600924T2 (de
Inventor
Iqbal W Dr Siddiqi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIGRIS RESEARCH, INC., BREA, CALIF., US
Original Assignee
Siddiqi Iqbal W
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siddiqi Iqbal W filed Critical Siddiqi Iqbal W
Publication of DE69600924D1 publication Critical patent/DE69600924D1/de
Application granted granted Critical
Publication of DE69600924T2 publication Critical patent/DE69600924T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/23Magnetic separation acting directly on the substance being separated with material carried by oscillating fields; with material carried by travelling fields, e.g. generated by stationary magnetic coils; Eddy-current separators, e.g. sliding ramp
    • B03C1/24Magnetic separation acting directly on the substance being separated with material carried by oscillating fields; with material carried by travelling fields, e.g. generated by stationary magnetic coils; Eddy-current separators, e.g. sliding ramp with material carried by travelling fields
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/451Magnetic mixers; Mixers with magnetically driven stirrers wherein the mixture is directly exposed to an electromagnetic field without use of a stirrer, e.g. for material comprising ferromagnetic particles or for molten metal
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/28Magnetic plugs and dipsticks
    • B03C1/288Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical applications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Processing Of Solid Wastes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
DE69600924T 1995-02-21 1996-02-16 Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen Expired - Lifetime DE69600924T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39114295A 1995-02-21 1995-02-21
PCT/US1996/002212 WO1996026011A1 (en) 1995-02-21 1996-02-16 Apparatus and method for mixing and separation employing magnetic particles

Publications (2)

Publication Number Publication Date
DE69600924D1 true DE69600924D1 (de) 1998-12-10
DE69600924T2 DE69600924T2 (de) 1999-06-10

Family

ID=23545436

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69600924T Expired - Lifetime DE69600924T2 (de) 1995-02-21 1996-02-16 Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen

Country Status (7)

Country Link
US (3) US6033574A (de)
EP (1) EP0810905B1 (de)
JP (1) JP3962789B2 (de)
AT (1) ATE172890T1 (de)
AU (1) AU4927496A (de)
DE (1) DE69600924T2 (de)
WO (1) WO1996026011A1 (de)

Families Citing this family (162)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030127396A1 (en) * 1995-02-21 2003-07-10 Siddiqi Iqbal Waheed Apparatus and method for processing magnetic particles
US6884357B2 (en) * 1995-02-21 2005-04-26 Iqbal Waheed Siddiqi Apparatus and method for processing magnetic particles
US6500343B2 (en) 1995-02-21 2002-12-31 Iqbal W. Siddiqi Method for mixing and separation employing magnetic particles
DE69600924T2 (de) 1995-02-21 1999-06-10 Siddiqi Iqbal W Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen
FR2758884B1 (fr) 1997-01-30 1999-04-02 Bio Merieux Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
US6616623B1 (en) * 1997-07-02 2003-09-09 Idializa Ltd. System for correction of a biological fluid
EP0905520B1 (de) * 1997-09-29 2008-03-26 F. Hoffmann-La Roche Ag Gerät zur Abscheidung magnetischer Teilchen
DE69839294T2 (de) * 1997-09-29 2009-04-09 F. Hoffmann-La Roche Ag Gerät zur Abscheidung magnetischer Teilchen
DK1614475T3 (da) 1998-05-01 2007-09-17 Gen Probe Inc Indretning til omröring af væskeindholdet i en beholder
US8337753B2 (en) * 1998-05-01 2012-12-25 Gen-Probe Incorporated Temperature-controlled incubator having a receptacle mixing mechanism
DE19823719B4 (de) * 1998-05-27 2011-12-15 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zum Aufkonzentrieren von Substanzen
US6776174B2 (en) * 1998-08-21 2004-08-17 Paul E. Nisson Apparatus for washing magnetic particles
US6551843B1 (en) 1999-01-29 2003-04-22 Immunivest Corporation Methods for enhancing binding interactions between members of specific binding pairs
US6357907B1 (en) * 1999-06-15 2002-03-19 V & P Scientific, Inc. Magnetic levitation stirring devices and machines for mixing in vessels
US6764859B1 (en) 1999-07-19 2004-07-20 Biomerieux, B.V. Device and method for mixing magnetic particles with a fluid
JP4651894B2 (ja) * 2000-01-04 2011-03-16 シディキ,イクバル,ダブリュー. 磁性粒子を利用した混合/分離装置及び方法
US6672458B2 (en) 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
WO2002016903A2 (en) * 2000-08-23 2002-02-28 Imego Ab Microfluidic device and method with trapping of sample in carities having lids that can be opened or closed
US6689615B1 (en) * 2000-10-04 2004-02-10 James Murto Methods and devices for processing blood samples
GB0029590D0 (en) * 2000-12-05 2001-01-17 Univ Heriot Watt Bio-strings
US6635181B2 (en) 2001-03-13 2003-10-21 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Continuous, hybrid field-gradient device for magnetic colloid based separations
CN1136923C (zh) * 2001-03-13 2004-02-04 张兴东 血磁机动磁场的充磁装置
DE10136060A1 (de) * 2001-07-25 2003-02-13 Roche Diagnostics Gmbh System zur Separation von magnetisch anziehbaren Partikeln
ATE309393T1 (de) * 2001-09-06 2005-11-15 Adnagen Ag Verfahren zum qualitativen und/oder quantitativen nachweis von zellen
DE10143775A1 (de) * 2001-09-06 2003-04-10 Adnagen Ag Verfahren und Kit zur Diagnostik oder Behandlungskontrolle von Darmkrebs
DE10143776A1 (de) * 2001-09-06 2003-04-03 Adnagen Ag Verfahren und Kit zur Diagnostik oder Behandlungskontrolle von Brustkrebs
FR2830204A1 (fr) * 2001-10-02 2003-04-04 Centre Nat Rech Scient Procede et dispositif de separation de particules marquees en suspension dans un milieu visqueux et son application aux processus microbiologiques
JP4089210B2 (ja) * 2001-11-16 2008-05-28 Jsr株式会社 磁気スタンド
DE10156790A1 (de) * 2001-11-19 2003-06-18 Chemagen Biopolymer Technologi Vorrichtung und Verfahren zum Behandeln von Magnetpartikeln
EP1448792A1 (de) * 2001-11-22 2004-08-25 Adnagen AG Diagnose-kit, dns-chip sowie verfahren zur diagnostik oder behandlungskontrolle bei hodenkrebs
US6954128B2 (en) * 2001-11-30 2005-10-11 The Regents Of The University Of California High performance hybrid magnetic structure for biotechnology applications
US7148778B2 (en) 2001-11-30 2006-12-12 The Regents Of The University Of California High performance hybrid magnetic structure for biotechnology applications
EP1487969A4 (de) * 2001-12-07 2008-07-09 Dyax Corp Verfahren und vorrichtung zum waschen von magnetisch reagierenden teilchen
US8367013B2 (en) * 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US20030119203A1 (en) * 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
WO2003073444A1 (en) * 2002-02-22 2003-09-04 Purdue Research Foundation Fe/au nanoparticles and methods
WO2003090897A1 (en) * 2002-04-26 2003-11-06 Abbott Laboratories Structure and method for handling magnetic particles in biological assays
CA2483694C (en) 2002-05-17 2016-04-19 Becton, Dickinson And Company Automated system for isolating, amplifying and detecting a target nucleic acid sequence
CA2491093A1 (en) * 2002-06-28 2004-01-08 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
US6988825B2 (en) * 2002-07-03 2006-01-24 Bio/Data Corporation Method and apparatus for using vertical magnetic stirring to produce turbulent and chaotic mixing in various states, without compromising components
US9435799B2 (en) * 2002-07-31 2016-09-06 Janssen Diagnostics, Inc. Methods and reagents for improved selection of biological materials
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7314763B2 (en) * 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7432105B2 (en) * 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7781172B2 (en) * 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US20040106190A1 (en) * 2002-12-03 2004-06-03 Kimberly-Clark Worldwide, Inc. Flow-through assay devices
US7247500B2 (en) * 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US7601491B2 (en) 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
US20040157219A1 (en) * 2003-02-06 2004-08-12 Jianrong Lou Chemical treatment of biological samples for nucleic acid extraction and kits therefor
JP4129864B2 (ja) * 2003-03-24 2008-08-06 農工大ティー・エル・オー株式会社 磁気微粒子の磁気分離装置
US20040197819A1 (en) * 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7851209B2 (en) * 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
EP1681570B1 (de) 2003-06-19 2008-11-05 Abbott Laboratories Vorrichtung und Verfahren zur Handhabung von Analyseflüssigkeiten
US8409528B2 (en) * 2003-06-19 2013-04-02 Abbott Laboratories Apparatus and method for handling fluids for analysis
CA2541241A1 (en) * 2003-08-26 2005-03-03 Danmarks Tekniske Universitet A continuous process for the assembly of macromolecular substances and the subsequent capture and isolation of a macromolecular assembly, and a system suitable for the process
FI20040159A0 (fi) 2003-10-20 2004-02-02 Bio Mobile Oy Magneettinen siirtomenetelmä, mikropartikkelien siirtolaite, ja reaktioyksikkö
JP4207754B2 (ja) * 2003-10-31 2009-01-14 和光純薬工業株式会社 磁性体を用いた免疫学的測定方法
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7943395B2 (en) * 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US20050136550A1 (en) * 2003-12-19 2005-06-23 Kimberly-Clark Worldwide, Inc. Flow control of electrochemical-based assay devices
US7943089B2 (en) * 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US20050266394A1 (en) * 2003-12-24 2005-12-01 Massachusette Institute Of Technology Magnetophoretic cell clarification
JP4732683B2 (ja) * 2003-12-29 2011-07-27 ユニバーサル・バイオ・リサーチ株式会社 標的物質の検出方法
US7572355B1 (en) 2004-01-07 2009-08-11 Board Of Trustees Of The University Of Arkansas Electrochemistry using permanent magnets with electrodes embedded therein
WO2005072855A1 (en) 2004-01-28 2005-08-11 Drexel University Magnetic fluid manipulators and methods for their use
US20050239091A1 (en) * 2004-04-23 2005-10-27 Collis Matthew P Extraction of nucleic acids using small diameter magnetically-responsive particles
CN101001945B (zh) * 2004-06-04 2012-02-08 艾克塞勒雷克斯公司 一次性生物反应器***及方法
US9790539B2 (en) * 2004-06-30 2017-10-17 Russell Biotech, Inc. Methods and reagents for improved selection of biological molecules
US7521226B2 (en) * 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US7094528B2 (en) * 2004-06-30 2006-08-22 Kimberly-Clark Worldwide, Inc. Magnetic enzyme detection techniques
US7906276B2 (en) * 2004-06-30 2011-03-15 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
CA2839092C (en) * 2004-08-03 2018-04-03 Becton, Dickinson And Company Use of magnetic material to direct isolation of compounds and fractionation of multipart samples
EP1773865A1 (de) * 2004-08-03 2007-04-18 Becton, Dickinson and Company Verwendung von magnetischem material zum fraktionieren von proben
US7699979B2 (en) * 2005-01-07 2010-04-20 Board Of Trustees Of The University Of Arkansas Separation system and efficient capture of contaminants using magnetic nanoparticles
US20060217893A1 (en) * 2005-01-07 2006-09-28 Yanbin Li Method for detecting an unknown contaminant concentration in a substance
AU2006223223B2 (en) * 2005-03-10 2012-04-12 Gen-Probe Incorporated Systems and methods to perform assays for detecting or quantifying analytes within samples
JP4422638B2 (ja) * 2005-03-23 2010-02-24 株式会社日立ハイテクノロジーズ 試料反応装置
EP1864141B1 (de) * 2005-03-28 2013-03-20 Becton, Dickinson & Company Verbessertes rührsystem und -verfahren für schwebstoffe in flüssigmedien
US20070036026A1 (en) * 2005-05-16 2007-02-15 Laibinis Paul E Magnetic Particle Systems and Methods
US20070020699A1 (en) * 2005-07-19 2007-01-25 Idexx Laboratories, Inc. Lateral flow assay and device using magnetic particles
US7564245B2 (en) 2005-08-31 2009-07-21 T2 Biosystems, Inc. NMR device for detection of analytes
US20070207272A1 (en) * 2006-03-03 2007-09-06 Puri Ishwar K Method and apparatus for magnetic mixing in micron size droplets
EP1839756A1 (de) * 2006-03-31 2007-10-03 F.Hoffmann-La Roche Ag Gerät zur Abscheidung magnetischer Teilchen aus teilchenhaltigen Flüssigkeiten, und einer Gruppe von Behältern zur Verwendung mit einem solchen Gerät
US8999732B2 (en) * 2006-06-21 2015-04-07 Spinomix, S.A. Method for manipulating magnetic particles in a liquid medium
US8870446B2 (en) 2006-06-21 2014-10-28 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
CN101522294B (zh) 2006-06-21 2012-05-16 斯彼诺米克斯公司 一种用于处理和混合液体介质中的磁性颗粒的设备和方法
US8585279B2 (en) * 2006-06-21 2013-11-19 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
EP2620771B1 (de) * 2006-07-24 2017-08-30 Becton Dickinson and Company Testpartikelkonzentrationsvorrichtung und -verfahren
US20100120016A1 (en) * 2006-09-01 2010-05-13 Yanbin Li Methods and systems for detection of contaminants
US8034245B1 (en) 2006-12-19 2011-10-11 The United States Of America As Represented By The United States Department Of Energy Method of driving liquid flow at or near the free surface using magnetic microparticles
US7883265B2 (en) * 2007-06-01 2011-02-08 Applied Biosystems, Llc Devices, systems, and methods for preparing emulsions
US20080309323A1 (en) * 2007-06-12 2008-12-18 Canon Kabushiki Kaisha Method for biochemical analysis
IL184183A0 (en) 2007-06-25 2007-10-31 Benjamin Alspector Bi directional transfer of an aliquot of fluid between compartments
AU2008273030B2 (en) * 2007-06-29 2013-01-17 Becton, Dickinson And Company Methods for extraction and purification of components of biological samples
EP2176669A1 (de) * 2007-07-25 2010-04-21 Abbott Laboratories Magnetmischer
TWI325337B (en) * 2007-07-26 2010-06-01 Ind Tech Res Inst Magnetic separation device
JP4586054B2 (ja) 2007-08-31 2010-11-24 株式会社日立ハイテクノロジーズ 自動分析装置
US7852470B2 (en) 2007-12-28 2010-12-14 Morpho Detection, Inc. System and method for improved biodetection
US20090169433A1 (en) * 2007-12-28 2009-07-02 Sankaran Kumar System for improved biodetection
US7847932B2 (en) 2007-12-28 2010-12-07 Morpho Detection, Inc. System and method for improved biodetection
US20090168592A1 (en) * 2007-12-28 2009-07-02 Michael Craig Burrell Agitator for portable substance identification system and method
JP2009222533A (ja) * 2008-03-17 2009-10-01 Hitachi High-Technologies Corp 自動分析装置
US20100077843A1 (en) * 2008-03-31 2010-04-01 Doraisamy Loganathan Substance identification apparatus and methods of using
US8689981B2 (en) 2009-04-10 2014-04-08 President And Fellows Of Harvard College Manipulation of particles in channels
EP2421654A1 (de) * 2009-04-22 2012-02-29 Clinical Genomics Pty Ltd Verfahren und vorrichtung zur isolierung einer biologischen zielentität aus einer biologische probe
DE102009021201A1 (de) * 2009-05-13 2010-11-25 Stratec Biomedical Systems Ag Stabanordnung und Verfahren zur Extraktion magnetisierbarer Partikel aus Lösungen
JP5775086B2 (ja) * 2009-10-16 2015-09-09 プロメガ・コーポレーション 加熱、加振、および磁化する装置、ならびにその装置を動作させる方法
EP2746777A3 (de) 2010-07-23 2014-08-27 Beckman Coulter, Inc. System oder Verfahren zur Aufnahme analytischer Einheiten
US9046507B2 (en) 2010-07-29 2015-06-02 Gen-Probe Incorporated Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure
WO2012019108A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Magnetic immunosensor with trench configuration and method of use
WO2012019107A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Magnetic immunosensor and method of use
US9329175B2 (en) 2010-08-05 2016-05-03 Abbott Point Of Care Inc. Oscillating immunoassay method and device
WO2012019104A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Immunoassay method and device with magnetically susceptible bead capture
EP2678664B1 (de) 2011-02-24 2019-08-07 Gen-Probe Incorporated Systeme und verfahren zur unterscheidung optischer signale mit verschiedenen modulationsfrequenzen bei einem optischen signaldetektor
WO2013009654A1 (en) 2011-07-08 2013-01-17 Life Technologies Corporation Method and apparatus for automated sample manipulation
WO2013070740A1 (en) 2011-11-07 2013-05-16 Beckman Coulter, Inc. Aliquotter system and workflow
KR20140091033A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 컨테이너 검출
BR112014011044A2 (pt) 2011-11-07 2017-04-25 Beckman Coulter Inc amortecimento magnético para sistema de transporte de espécime
ES2729283T3 (es) 2011-11-07 2019-10-31 Beckman Coulter Inc Sistema de centrífuga y flujo de trabajo
KR20140092378A (ko) 2011-11-07 2014-07-23 베크만 컬터, 인코포레이티드 샘플을 처리하기 위한 시스템 및 방법
EP2776845B1 (de) 2011-11-07 2020-11-04 Beckman Coulter, Inc. Roboterarm
US9446406B2 (en) 2012-06-29 2016-09-20 Biocontrol Systems, Inc. Sample collection and bioluminescent analysis system
JP2014093988A (ja) * 2012-11-12 2014-05-22 Seiko Epson Corp 固相担体の操作方法及び固相担体の操作装置
EP2972403B1 (de) 2013-03-15 2022-12-07 Abbott Laboratories Automatisierte diagnostische analysevorrichtungen mit vertikal angeordneten karussellen und zugehörige verfahren
EP3964839B1 (de) 2013-03-15 2024-04-10 Abbott Laboratories Automatisierte diagnostische analysatoren mit rückwärtig zugänglichen führungsspursystemen und zugehörige verfahren
EP2972402B1 (de) 2013-03-15 2023-12-20 Abbott Laboratories Diagnostische analysevorrichtung und vorbehandlungskarussells und zugehörige verfahren
DE102013009773B4 (de) * 2013-06-05 2016-02-11 Technische Universität Dresden Vorrichtung sowie Verfahren zur Steigerung der Anbindungseffizienz von zur Bindung befähigten Zielstrukturen
WO2014194947A1 (en) * 2013-06-06 2014-12-11 Tecan Trading Ag Magnetic coupling and mixing device, method and use
CN111362988B (zh) 2013-11-12 2024-03-15 生命科技公司 用于乳状液分解的***和方法
JP6350654B2 (ja) * 2014-05-23 2018-07-04 株式会社島津製作所 磁性体粒子の操作方法
WO2015191877A1 (en) 2014-06-11 2015-12-17 Life Technologies Corporation Systems and methods for substrate enrichment
WO2016002727A1 (ja) 2014-06-30 2016-01-07 パナソニックヘルスケアホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
US10539582B2 (en) 2014-06-30 2020-01-21 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and method for removing liquid from liquid that contains magnetic particles
US10520521B2 (en) 2014-06-30 2019-12-31 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
JP6548645B2 (ja) 2014-06-30 2019-07-24 Phcホールディングス株式会社 試料分析用基板および試料分析装置
US10539583B2 (en) 2014-12-12 2020-01-21 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
US20160291002A1 (en) * 2015-03-12 2016-10-06 Pathogen Systems, Inc. dba Crystal Diagnostics Ltd Sample Preparation and Specific Capture for Multiplex Detection of Target Analytes (i.e., Bacteria, Viruses, Etc.)
FR3038526A1 (fr) * 2015-07-06 2017-01-13 Provaine Systeme de fabrication d'une formulation
EP3349823B1 (de) 2015-09-14 2022-01-26 Medisieve Ltd Magnetfiltervorrichtung
WO2017093896A1 (en) 2015-11-30 2017-06-08 Dh Technologies Development Pte. Ltd. Electromagnetic assemblies for processing fluids
JP2019512208A (ja) 2016-01-21 2019-05-16 ティー2 バイオシステムズ,インコーポレーテッド 細菌を迅速に検出するnmr法及びシステム
AU2017304767A1 (en) 2016-07-28 2019-01-17 Medisieve Ltd. Magnetic mixer and method
US10590409B2 (en) * 2016-12-06 2020-03-17 Wisconsin Alumni Research Foundation Method and device for disaggregation via heterogeneous particles
US10427162B2 (en) 2016-12-21 2019-10-01 Quandx Inc. Systems and methods for molecular diagnostics
US11828691B2 (en) * 2017-01-27 2023-11-28 Dh Technologies Development Pte. Ltd. Electromagnetic assemblies for processing fluids
WO2018185672A1 (en) * 2017-04-06 2018-10-11 Magbiosense Inc. Bio-assay capture surfaces with bleached autofluorescence
US20200360879A1 (en) 2017-11-21 2020-11-19 Dh Technologies Development Pte. Ltd. 3-D Mixing and Particle Delivery Via Movable Electromagnets Assemblies
JP6782264B2 (ja) * 2018-02-20 2020-11-11 株式会社日立ハイテク 自動分析装置
JP7020308B2 (ja) * 2018-06-14 2022-02-16 株式会社島津製作所 磁性体粒子操作用装置
CN117138854A (zh) * 2018-07-20 2023-12-01 Dh科技发展私人贸易有限公司 用于处理流体的电磁线圈组件结构及其制造方法
KR102256776B1 (ko) 2018-07-26 2021-05-27 (주)바이오니아 자석봉 블록의 교체가 가능한 표적물질 추출장치
US10903184B2 (en) * 2018-08-22 2021-01-26 International Business Machines Corporation Filler particle position and density manipulation with applications in thermal interface materials
EP3887049B1 (de) * 2018-11-28 2023-07-12 V & P Scientific, Inc. Spinnbehältersysteme und verfahren zum mischen, suspendieren von partikeln, aliquotieren, waschen von magnetischen kügelchen und konzentrieren von analyten
US20220260481A1 (en) * 2019-07-02 2022-08-18 The Regents Of The University Of California Magnetically modulated computational cytometer and methods of use
WO2021097430A1 (en) * 2019-11-15 2021-05-20 Redbud Labs, Inc. Magnetic-based actuation mechanisms for actuating magnetically-responsive microposts in a reaction chamber
CN115052676A (zh) * 2019-11-27 2022-09-13 Jbs科学公司 在液体介质中混合磁性颗粒的方法和装置
KR102370210B1 (ko) * 2020-10-13 2022-03-04 한국전자기술연구원 나노입자의 극성 및 분산성 평가 장치 및 방법
CN113186098B (zh) * 2021-05-28 2024-03-26 宁波康程德诺生物医药有限公司 一种一体化下开口核酸快提试管、快提检测装置及方法
CN114602966B (zh) * 2022-02-24 2023-03-21 上海市园林工程有限公司 一种用于重金属污染土壤的修复方法
CN114713367B (zh) * 2022-03-16 2023-07-18 青岛瑞斯凯尔生物科技有限公司 一种用于流式前样本处理仪的振荡磁分离装置及其方法
CN115254834B (zh) * 2022-08-02 2023-10-27 宋世琦 用于免疫分析设备的磁微粒清洗装置及清洗方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985649A (en) 1974-11-25 1976-10-12 Eddelman Roy T Ferromagnetic separation process and material
US4230685A (en) * 1979-02-28 1980-10-28 Northwestern University Method of magnetic separation of cells and the like, and microspheres for use therein
US4390283A (en) * 1979-09-04 1983-06-28 Beckman Instruments, Inc. Magnetic strirrer for sample container
FR2466282A1 (fr) * 1979-10-02 1981-04-10 Commissariat Energie Atomique Procede d'elimination des elements metalliques lourds en suspension dans un liquide a l'aide d'un adjuvant ferromagnetique finement divise
JPS5753257A (en) 1980-09-16 1982-03-30 Tohoku Metal Ind Ltd Apparatus for separating magnetic particulate body
US4390233A (en) * 1981-04-21 1983-06-28 Sanders Jr David E B Battery cable connector
JPS58193A (ja) 1981-06-25 1983-01-05 日立化成工業株式会社 印刷配線板の製造法
JPS588562A (ja) * 1981-07-08 1983-01-18 Japan Atom Energy Res Inst 磁性粉粒体の分離装置
JPS58193687A (ja) * 1982-05-10 1983-11-11 Res Dev Corp Of Japan 微小物の撹拌分離方法
US4628037A (en) * 1983-05-12 1986-12-09 Advanced Magnetics, Inc. Binding assays employing magnetic particles
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
CH668919A5 (de) * 1984-05-07 1989-02-15 Dieter Alex Rufer Geraet zum ruehren oder pumpen eines mediums.
SU1245343A1 (ru) * 1985-02-08 1986-07-23 Институт Минеральных Ресурсов Министерства Геологии Усср Способ магнитной сепарации тонкоизмельченных сильномагнитных материалов
NO162946C (no) * 1987-08-21 1990-03-14 Otto Soerensen Anordning for magnetisk separasjon av celler.
US5238812A (en) * 1987-03-13 1993-08-24 Coulter Corporation Method and apparatus for rapid mixing of small volumes for enhancing biological reactions
US4895650A (en) * 1988-02-25 1990-01-23 Gen-Probe Incorporated Magnetic separation rack for diagnostic assays
EP0491858A1 (de) * 1989-09-14 1992-07-01 Baxter International Inc. Vorrichtung und verfahren zur herstellung von arzneimittelzubereitungen
GB8927744D0 (en) * 1989-12-07 1990-02-07 Diatec A S Process and apparatus
US5043063A (en) * 1990-03-21 1991-08-27 Eriez Manufacturing Company Magnetic trap and cleaning means therefor
US5628407A (en) * 1994-12-05 1997-05-13 Bolt Beranek And Newman, Inc. Method and apparatus for separation of magnetically responsive spheres
DE69600924T2 (de) 1995-02-21 1999-06-10 Siddiqi Iqbal W Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen

Also Published As

Publication number Publication date
JPH11500952A (ja) 1999-01-26
EP0810905B1 (de) 1998-11-04
US6228268B1 (en) 2001-05-08
US6033574A (en) 2000-03-07
EP0810905A1 (de) 1997-12-10
DE69600924T2 (de) 1999-06-10
ATE172890T1 (de) 1998-11-15
WO1996026011A1 (en) 1996-08-29
JP3962789B2 (ja) 2007-08-22
AU4927496A (en) 1996-09-11
US6231760B1 (en) 2001-05-15

Similar Documents

Publication Publication Date Title
DE69600924D1 (de) Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen
ATE306328T1 (de) Apparat und verfahren zum mischen und trennen unter benützung magnetischer teilchen
DE69401359D1 (de) Verfahren und vorrichtung zur bestimmung eines analyten in einer probe
DK159170C (da) Fremgangsmaade og apparat til bestemmelse af maengden af mineralsk og organisk kulstof i en sedimentproeve
DE60110256D1 (de) Verfahren zum konzentrieren von analyten in proben
DK0644426T3 (da) Analyseudstyr med en indretning til suspendering af partikler og en fremgangsmåde til udförelse af suspenderingen
AU2045692A (en) Process and magnetic device for immunological analysis of a solid phase
CA2103674A1 (en) Methods and apparatus for improved luminescence assays
DK541687D0 (da) Fremgangsmaade og apparat til ikke-destruktiv materialeafproevning og undersoegelse af magnetostrukturelle materialer
ATE9962T1 (de) Verfahren und vorrichtung zum durchfuehren von reaktionen in einem fluiden medium.
CA2124304A1 (en) Capsule chemistry sample liquid analysis system and method
DE69614205T2 (de) Verfahren und vorrichtung zur bestimmung eines analyten, insbesondere eines bakteriums, auf magnetischem wege
DK0658566T3 (da) Fremgangsmåde til fremstilling af polynukleotider på et fast underlag samt apparat til udførelse af fremgangsmåden
DE69329135T2 (de) Verfahren und Vorrichtung zur magnetischen Abscheidung
BE877044A (nl) Werkwijze en inrichting voor het door middel van gasbellen opdrijfbaar maken van in een vloeistof gesuspendeerde deeltjes
FI956135A (fi) Erotusmenetelmä
ATE116443T1 (de) Festphasenanalytische vorrichtung und verfahren zum gebrauch derselben.
ES2013228B3 (es) Separador para agregados y sistema empleado en tal aparato.
DE60206707D1 (de) Vorrichtung und Verfahren zum Rühren von Teilchen in Suspension in einem flüssigen Medium
EP0228473A4 (de) Vorrichtung zur zerstörungsfreien feststellung von rissen in metallischen materialien mit hilfe eines magnetischen feldes.
DE69019408D1 (de) Verfahren und Apparat zur Verminderung von Basisfeldveränderungen in einem magnetischen Resonanzgerät, verursacht durch gepulste magnetische Feldgradienten.
ATE76780T1 (de) Mischvorrichtung und verfahren.
FR2545009B1 (fr) Appareil et procede pour le tri de particules par agitation de gaz
EP0427089A3 (en) Laboratory apparatus for the separation of substances from gas samples
US20200231961A1 (en) Device For Facilitating The Isolation Of Targets From A Biological Sample

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SIGRIS RESEARCH, INC., BREA, CALIF., US

8381 Inventor (new situation)

Inventor name: SIDDIQI, IQBAL W., DR., BREA, CALIF., US

R082 Change of representative

Ref document number: 810905

Country of ref document: EP

Representative=s name: DF-MP, 80333 MUENCHEN, DE